CN214422655U - CIK cell culture device with buffer protection - Google Patents

Abstract

The utility model discloses a CIK cell culture device with buffering protection, including incubator, mark structure, mark piece, mark lid, glass board, head rod, slider, push rod, rotary rod, bracing piece, first spring, fixed knot construct and clamping structure. The utility model has the advantages that: the bottom end of the mark cover is fixed with a first spring, and the other end of the first spring and the mark cover are fixedly connected, so that the mark cover can be pulled back, the mark can not drop due to jolting in the transportation process, a plurality of fixing structures are arranged on the top of the incubator, the automatic adjustment inlet of the culture test tubes can be adjusted according to different sizes, the culture test tubes can be fixed, a plurality of clamping structures are arranged inside the incubator, the culture test tubes can be clamped, and the bottom end of the incubator is prevented from colliding with the inside of the incubator.

Description

CIK cell culture device with buffer protection

Technical Field

The utility model relates to a culture apparatus specifically is a CIK cell culture device with buffering protection, belongs to cell culture technical field.

Background

In recent years, research, development and application of CIK cells are deepened, mature CIK cell induction and culture methods are formed, but in the culture process of the CIK cells, more reagents are adopted, the standards are inconsistent, the workload in the culture process is large, the culture time is long, the risk of contamination is large, and a plurality of researchers, particularly workers in hospitals at all levels, are difficult to culture the CIK cells with uniform quality in a short time.

In the cultivation process of incubator, generally can remove the incubator at the cultivation in-process, but the mark can often oneself long-time oxidation lead to bonding insecure for do not know corresponding cultivation test tube usually when taking out the cultivation test tube, consequently, get back when taking out the cultivation test tube and lead to getting the mistake, cause very big loss.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a CIK cell culture device with buffering protection just for solving above-mentioned problem, protection mark that can be good can not take place to drop in mark structure, and fixed knot constructs and clamping structure can place and avoid cultivateing test tube bottom and incubator inside the collision of giving birth to according to the not cultivation test tube of equidimension.

The utility model realizes the above purpose by the following technical proposal, a CIK cell culture device with buffer protection comprises an incubator and a plurality of marking structures arranged at one end of the incubator, wherein the plurality of marking structures comprise marking blocks, marking covers, glass plates, first connecting rods, sliders, push rods, rotary rods, support rods and first springs, one end of the incubator is provided with a plurality of marking blocks, the marking blocks are in parallel symmetrical relation, the marking covers are arranged at the top ends of the marking blocks, the glass plates are arranged inside the marking blocks, two first connecting rods are arranged inside the marking blocks, the two first connecting rods are in symmetrical relation, the sliders are connected with the outsides of the two first connecting rods in a sliding way, and one ends of the two sliders are provided with the push rods, the two push rods are in a symmetrical relation, one end of each of the two sliding blocks is rotatably connected with the rotating rod, the two support rods are slidably connected inside the plurality of marking blocks and are symmetrically distributed, the two support rods are respectively rotatably connected with the two rotating rods, the other ends of the two support rods are fixed on the marking cover, the two first springs are arranged inside the plurality of marking blocks and are in a symmetrical relation; the top of incubator is equipped with a plurality of fixed knot and constructs the inside of incubator is equipped with a plurality of clamping structure.

Preferably, in order to facilitate the movement and positioning of the incubator, a plurality of rollers are arranged at the bottom end of the incubator, and the rollers are symmetrically distributed in pairs.

Preferably, in order to facilitate transportation and movement of the incubator, a push-pull structure is arranged at one end of the incubator, the push-pull structure comprises a fixed sleeve, a first push-pull rod, a second push-pull rod, a push handle, a clamping sleeve, a protrusion and a groove, the fixed sleeve is fixed at one end of the incubator, the first push-pull rod is rotatably connected to one end of the fixed sleeve, the second push-pull rod is slidably connected to the inside of the first push-pull rod, the groove is arranged on the outside of the first push-pull rod, the clamping sleeve is fixed at one end of the incubator, which is close to the fixed sleeve, and the arc-shaped protrusion is fixed inside the clamping sleeve.

Preferably, in order to ensure that the second push-pull rod cannot completely slide out of the first push-pull rod, the push-pull structure further comprises a waist-shaped groove and a fixing column, the waist-shaped groove is formed in the first push-pull rod, the fixing column of the cylindrical structure is fixed on the outer portion of the second push-pull rod, and the fixing column is connected with the first push-pull rod in a sliding mode through the waist-shaped groove.

Preferably, in order to conveniently put culture test tubes with different sizes and fix the culture test tubes, the fixing structure comprises a fixing block, a cover plate, a positioning block, a connecting block, a second connecting rod and a second spring, the top end of the incubator is provided with a plurality of fixed blocks, the top ends of the fixed blocks are connected with a plurality of cover plates in a sliding way, the cover plates are symmetrical in pairs, the positioning blocks are arranged at the bottom ends of the cover plates, the positioning blocks are in pairwise symmetrical relation, one end of each positioning block is provided with the connecting block, the plurality of connecting blocks are in pairwise symmetrical relation, one end of each connecting block is provided with the second connecting rod, and a plurality of the second connecting rods are all connected with the fixed block in a sliding manner, two second springs are arranged at one ends of the connecting blocks, and the second springs are in pairwise symmetry.

Preferably, the incubator moves when the transportation, in order to avoid the collision of the culture test tube with the inside of the incubator, clamping structure includes clamp splice, rubber block, third connecting rod and third spring the inside sliding connection of incubator has a plurality of the clamp splice, and per two are symmetrical relation, and are a plurality of the one end of clamp splice all is equipped with the rubber block, and is a plurality of the equal sliding connection of clamp splice has the third connecting rod, and is a plurality of the other end of third connecting rod all with incubator fixed connection, it is a plurality of the one end of clamp splice all is equipped with two the third spring, and is a plurality of the third spring all with incubator fixed connection.

The utility model has the advantages that: the utility model discloses a through set up a plurality of mark structures in the one end of incubator to carry out the mark to the cell of cultivateing, incubator one end is equipped with a plurality of mark pieces, and a plurality of mark pieces are parallel symmetry relation, the mark lid has all been placed on the top of a plurality of mark pieces, the inside of a plurality of mark pieces all is equipped with the glass board, the inside of a plurality of mark pieces all is equipped with two head rods, and two head rods are symmetry relation, two head rods outside all sliding connection have the slider, two slider bottom all are equipped with the push rod, and two push rods are symmetry relation, two slider one end all rotating connection have the rotary rod, the inside of a plurality of mark pieces all sliding connection have two bracing pieces, and two bracing pieces are symmetrical distribution, two bracing pieces respectively rotating connection with two rotary rods, and the other end of two bracing pieces is fixed in the mark lid, the inside of a plurality of mark pieces all is equipped with two first springs, the two first springs are in a symmetrical relation, the push rods drive the sliding block by pushing the two push rods, the sliding block is in sliding connection with the first connecting rod, so that the sliding block is driven to slide back and forth on the first connecting rod, the sliding block drives the rotating rod fixed at one end of the sliding block in a sliding way, the other end of the rotating rod is in rotating connection with the supporting rod, so that the supporting rod is driven to move up and down, the marking cover is driven to move up and down, the first springs are fixed at the bottom end of the marking cover, and the other end of the first springs are fixedly connected with the marking block, so that the marking cannot fall off due to bumping during transportation, a plurality of fixing structures are arranged at the top end of the incubator, the inlet can be automatically adjusted according to the culture test tubes with different sizes, the culture test tubes can be fixed, a plurality of clamping structures are arranged inside the incubator, and the placed culture test tubes can be clamped, so that the bottom end of the incubator can avoid collision with the inside of the incubator.

Drawings

Fig. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a schematic structural diagram of the marking structure shown in FIG. 1;

FIG. 3 is a schematic structural view of the fastening structure shown in FIG. 1;

FIG. 4 is a schematic view showing a coupling structure of the cultivation box and the holding structure shown in FIG. 1;

FIG. 5 is a schematic structural view of the push-pull configuration shown in FIG. 1;

FIG. 6 is an enlarged view of portion A of FIG. 2;

in the figure: 1. the incubator comprises an incubator, 2, a marking structure, 21, a marking block, 22, a marking cover, 23, a glass plate, 24, a first connecting rod, 25, a sliding block, 26, a push rod, 27, a rotating rod, 28, a support rod, 29, a first spring, 3, a push-pull structure, 31, a fixing sleeve, 32, a first push-pull rod, 33, a second push-pull rod, 34, a push handle, 35, a jacket, 36, a protrusion, 37, a groove, 38, a waist-shaped groove, 39, a fixing column, 4, a pulley, 5, a fixing structure, 51, a fixing block, 52, a cover plate, 53, a positioning block, 54, a connecting block, 55, a second connecting rod, 56, a second spring, 6, a clamping structure, 61, a clamping block, 62, a rubber block, 63, a third connecting rod, 64 and a third spring.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-6, a CIK cell culture apparatus with buffer protection includes an incubator 1 and a plurality of marker structures 2 disposed at one end of the incubator 1, each of the marker structures 2 includes a marker block 21, a marker cover 22, a glass plate 23, a first connecting rod 24, a slider 25, a push rod 26, a rotating rod 27, a support rod 28, and a first spring 29, the marker blocks 21 are disposed at one end of the incubator 1, the marker blocks 21 are in parallel symmetry, the marker covers 22 are disposed at top ends of the marker blocks 21, the glass plate 23 is disposed inside the marker blocks 21, two first connecting rods 24 are disposed inside the marker blocks 21, the two first connecting rods 24 are in symmetry, the slider 25 is slidably connected to outer portions of the two first connecting rods 24, the push rods 26 are arranged at one ends of the two slide blocks 25, the two push rods 26 are in a symmetrical relation, one ends of the two slide blocks 25 are rotatably connected with the rotating rods 27, the two support rods 28 are slidably connected inside the plurality of mark blocks 21 and are symmetrically distributed, the two support rods 28 are respectively rotatably connected with the two rotating rods 27, the other ends of the two support rods 28 are fixed on the mark cover 22, the two first springs 29 are arranged inside the plurality of mark blocks 21, and the two first springs 29 are in a symmetrical relation; the top end of the incubator 1 is provided with a plurality of fixing structures 5, and the inside of the incubator 1 is provided with a plurality of clamping structures 6.

As a technical optimization scheme of the utility model, the bottom of stating incubator 1 is equipped with a plurality of gyro wheels 4, and is a plurality of gyro wheel 4 is two bisymmetry distributions.

As a technical optimization scheme of the utility model, the one end of incubator 1 is equipped with push-and-pull structure 3, push-and-pull structure 3 is including fixed cover 31, first push-and-pull rod 32, second push-and-pull rod 33, pushing hands 34, clamp cover 35, arch 36 and recess 37 the one end of incubator 1 is fixed cover 31 the one end of fixed cover 31 is rotated and is connected with first push-and-pull rod 32 the inside sliding connection of first push-and-pull rod 32 has second push-and-pull rod 33 the outside of first push-and-pull rod 32 is equipped with recess 37 incubator 1 is close to the one end of fixed cover 31 is fixed clamp cover 35 the fixed arc of inside that presss from both sides cover 35 arch 36.

As a technical optimization scheme of the present invention, the push-pull structure 3 further includes a waist-shaped groove 38 and a fixing column 39, the waist-shaped groove 38 is disposed on the first push-pull rod 32, the cylinder structure is fixed outside the second push-pull rod 33, the fixing column 39 is fixed outside the second push-pull rod 33, and the fixing column 39 passes through the waist-shaped groove 38 and the first push-pull rod 32 are slidably connected.

As a technical optimization scheme of the present invention, the fixing structure 5 includes a fixing block 51, a cover plate 52, a plurality of fixing blocks 53, a connecting block 54, a second connecting rod 55 and a second spring 56, the top end of the incubator 1 is provided with a plurality of fixing blocks 51, a plurality of fixing blocks 51 are all slidably connected to a plurality of cover plates 52, and a plurality of cover plates 52 are in two-two symmetry relationship, a plurality of cover plates 52 are all provided with the positioning blocks 53, a plurality of positioning blocks 53 are in two-two symmetry relationship, one end of the plurality of positioning blocks 53 is provided with the connecting block 54, a plurality of connecting blocks 54 are in two-two symmetry relationship, one end of each connecting block 54 is provided with the second connecting rod 55, and a plurality of second connecting rods 55 are all slidably connected to the fixing blocks 51, and one end of each connecting block 54 is provided with two second springs 56, and a plurality of the second springs 56 are in a pairwise symmetrical relationship.

As a technical optimization scheme of the utility model, clamping structure 6 includes clamp splice 61, block rubber 62, third connecting rod 63 and third spring 64 incubator 1's inside sliding connection has a plurality ofly clamp splice 61, and per two are symmetrical relation, and is a plurality of clamp splice 61's one end all is equipped with block rubber 62, and is a plurality of clamp splice 61 equal sliding connection has third connecting rod 63, and is a plurality of the other end of third connecting rod 63 all with incubator 1 fixed connection, it is a plurality of clamp splice 61's one end all is equipped with two third spring 64, and a plurality of third spring 64 all with incubator 1 fixed connection.

When the utility model is used, firstly, the incubator 1 is pushed to a place to be placed through the roller 4 and is fixed through the matching of the groove 37 on the first push-pull rod 32 and the protrusion 36 on the jacket 35, the first push-pull rod 32 can be clamped and limited, the first push-pull rod 32 is prevented from falling off when the first push-pull rod 32 is not used, and the second push-pull rod 33 is slidably connected in the first push-pull rod 32, so that the incubator 1 can be conveniently pushed and pulled, the second push-pull rod 33 can be conveniently stored, the incubator can not occupy space when not used, then the culture test tube is slowly put into the incubator 1 through the fixing structure 5, the top end of the incubator 1 is provided with the fixing block 51, the top end of the fixing block 51 is all slidably connected with the cover plate 52, the bottom end of the cover plate 51 is all provided with the positioning block 53, one end of the positioning block 53 is all provided with the connecting block 54, one end of the connecting block 54 is all provided with the second connecting rod 55, the second connecting rod 55 is slidably connected with the fixed block 51, one end of the connecting block 54 is provided with two second springs 56, the two second springs 56 are in a symmetrical relation, the culture test tube is placed in the incubator 1, the bottom end of the culture test tube is clamped through the clamping structure 6 in the incubator 1, the inside of the incubator 1 is slidably connected with the clamping block 61, one end of the clamping block 61 is provided with the rubber block 62, the clamping block 61 is slidably connected with the third connecting rod 63, the other end of the third connecting rod 63 is fixedly connected with the incubator 1, one end of the clamping block 61 is provided with two third springs 64, the plurality of third springs 64 are fixedly connected with the incubator 1, the cover plate 5 is pushed by slowly inserting the culture test tube, the cover plate 52 is slidably connected with the fixed block 51, the bottom end of the cover plate 52 is connected with the positioning block 53, as the positioning block 53 cannot be displaced, the second springs 56 are connected between the positioning block 53 and the fixed block 51, therefore, a culture test tube can be fixed, after the culture test tube is inserted, the clamping block 61 is slowly pushed, one end of the clamping block 61 is provided with the rubber block 62, so that the abrasion of the culture test tube cannot be caused, the clamping block 61 is slidably connected with the incubator 1 through the third connecting rod 63, the third spring 64 is connected between the clamping block 61 and the incubator 1, so that the clamping block 61 cannot be scratched by the third connecting rod 63, the bottom end of the culture test tube inserted is fixed through the clamping structure 6, the collision between the bottom of the culture test tube and the inside of the incubator 1 is avoided, one end of the incubator 1 is provided with the plurality of marking structures 2, so that cultured cells are marked, one end of the incubator 1 is provided with the plurality of marking blocks 21, the plurality of marking blocks 21 are in parallel symmetry, the marking covers 22 are placed at the top ends of the plurality of marking blocks 21, the glass plates 23 are arranged inside the plurality of marking blocks 21, two first connecting rods 24 are arranged inside the plurality of marking blocks 21, the two first connecting rods 24 are in a symmetrical relationship, the sliding blocks 25 are slidably connected to the outer portions of the two first connecting rods 24, the bottom ends of the two sliding blocks 25 are respectively provided with a push rod 26, the two push rods 26 are in a symmetrical relationship, one end of each of the two sliding blocks 25 is rotatably connected with a rotating rod 27, the inner portions of the marking blocks 21 are respectively slidably connected with two supporting rods 28, the two supporting rods 28 are symmetrically distributed, the two supporting rods 28 are respectively rotatably connected with the two rotating rods 27, the other ends of the two supporting rods 28 are fixed on the marking cover 22, the inner portions of the marking blocks 21 are respectively provided with two first springs 29, the two first springs 29 are in a symmetrical relationship, the push rods 26 are pushed to drive the sliding blocks 25, the sliding blocks 25 are slidably connected with the first connecting rods 24, the sliding blocks 25 are driven to slide back and forth on the first connecting rods 24, and the sliding blocks 25 slidably drive the rotating rods 27 fixed at one ends of the sliding blocks 25, the other end of the rotating rod 27 is rotatably connected with a supporting rod 28, so that the supporting rod 28 is driven to move up and down, the marking cover 22 moves up and down, a first spring 29 is fixed at the bottom end of the marking cover 22, and the other end of the first spring 29 is fixedly connected with the marking block 21, so that the marking cover 22 can be pulled back by itself, and the marking cannot fall off due to bumping during transportation.

It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (6)

1. The utility model provides a CIK cell culture device with buffering protection, includes incubator (1) and locates a plurality of mark structure (2) of incubator (1) one end, its characterized in that: a plurality of the mark structures (2) comprise mark blocks (21), mark covers (22), glass plates (23), first connecting rods (24), sliding blocks (25), push rods (26), rotating rods (27), supporting rods (28) and first springs (29), one end of the incubator (1) is provided with a plurality of the mark blocks (21), the mark blocks (21) are in parallel symmetrical relation, the mark covers (22) are placed at the top ends of the mark blocks (21), the glass plates (23) are arranged inside the mark blocks (21), two first connecting rods (24) are arranged inside the mark blocks (21), the two first connecting rods (24) are in symmetrical relation, the sliding blocks (25) are connected outside the first connecting rods (24) in a sliding way, the push rods (26) are arranged at one end of each sliding block (25), the two push rods (26) are in a symmetrical relation, one end of each of the two sliding blocks (25) is rotatably connected with the corresponding rotating rod (27), the two supporting rods (28) are slidably connected inside the corresponding marking blocks (21) and are symmetrically distributed, the two supporting rods (28) are respectively rotatably connected with the two rotating rods (27), the other ends of the two supporting rods (28) are fixed on the corresponding marking cover (22), the two first springs (29) are arranged inside the corresponding marking blocks (21), and the two first springs (29) are in a symmetrical relation; the top of incubator (1) is equipped with a plurality of fixed knot structure (5), is equipped with a plurality of clamping structure (6) in the inside of incubator (1).

2. The CIK cell culture device with buffer protection as claimed in claim 1, wherein: the bottom of incubator (1) is equipped with a plurality of gyro wheels (4), and is a plurality of gyro wheel (4) are two liang of symmetric distribution.

3. The CIK cell culture device with buffer protection as claimed in claim 1, wherein: the novel incubator is characterized in that one end of the incubator (1) is provided with a push-pull structure (3), the push-pull structure (3) comprises a fixed sleeve (31), a first push-pull rod (32), a second push-pull rod (33), a push handle (34), a jacket (35), a protrusion (36) and a groove (37), the fixed sleeve (31) is fixed at one end of the incubator (1), the first push-pull rod (32) is rotatably connected at one end of the fixed sleeve (31), the second push-pull rod (33) is slidably connected inside the first push-pull rod (32), the groove (37) is arranged outside the first push-pull rod (32), the jacket (35) is fixed at one end, close to the fixed sleeve (31), of the incubator (1), and the arc-shaped protrusion (36) is fixed inside the jacket (35).

4. The CIK cell culture device with buffer protection as claimed in claim 3, wherein: the push-pull structure (3) further comprises a waist-shaped groove (38) and a fixing column (39), the waist-shaped groove (38) is formed in the first push-pull rod (32), the fixing column (39) of the cylindrical structure is fixed to the outer portion of the second push-pull rod (33), and the fixing column (39) is connected with the first push-pull rod (32) in a sliding mode through the waist-shaped groove (38).

5. The CIK cell culture device with buffer protection as claimed in claim 1, wherein: the fixing structure (5) comprises fixing blocks (51), cover plates (52), positioning blocks (53), connecting blocks (54), second connecting rods (55) and second springs (56), the top end of the incubator (1) is provided with a plurality of the fixing blocks (51), the top ends of the fixing blocks (51) are all in sliding connection with the cover plates (52), the cover plates (52) are in pairwise symmetry, the bottom ends of the cover plates (52) are provided with the positioning blocks (53), the positioning blocks (53) are in pairwise symmetry, one ends of the positioning blocks (53) are provided with the connecting blocks (54), the connecting blocks (54) are in pairwise symmetry, one ends of the connecting blocks (54) are provided with the second connecting rods (55), and the second connecting rods (55) are all in sliding connection with the fixing blocks (51), one end of each of the connecting blocks (54) is provided with two second springs (56), and the second springs (56) are in pairwise symmetry.

6. The CIK cell culture device with buffer protection as claimed in claim 1, wherein: clamping structure (6) are including clamp splice (61), block rubber (62), third connecting rod (63) and third spring (64) the inside sliding connection of incubator (1) is a plurality of clamp splice (61), and every two are symmetrical relation, and is a plurality of the one end of clamp splice (61) all is equipped with block rubber (62), and is a plurality of the equal sliding connection of clamp splice (61) has third connecting rod (63), and is a plurality of the other end of third connecting rod (63) all with incubator (1) fixed connection, it is a plurality of the one end of clamp splice (61) all is equipped with two third spring (64), and a plurality of third spring (64) all with incubator (1) fixed connection.

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