CN214419671U - Heparin sodium apparatus for producing that dehydration rate is high - Google Patents
Heparin sodium apparatus for producing that dehydration rate is high Download PDFInfo
- Publication number
- CN214419671U CN214419671U CN202023005874.6U CN202023005874U CN214419671U CN 214419671 U CN214419671 U CN 214419671U CN 202023005874 U CN202023005874 U CN 202023005874U CN 214419671 U CN214419671 U CN 214419671U
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- China
- Prior art keywords
- extrusion
- heparin sodium
- storehouse
- fixedly connected
- dehydration rate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229920000669 heparin Polymers 0.000 title claims abstract description 66
- ZFGMDIBRIDKWMY-PASTXAENSA-N heparin Chemical compound CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 title claims abstract description 66
- 229960001008 heparin sodium Drugs 0.000 title claims abstract description 66
- 230000018044 dehydration Effects 0.000 title claims abstract description 33
- 238000006297 dehydration reaction Methods 0.000 title claims abstract description 33
- 238000001125 extrusion Methods 0.000 claims abstract description 87
- 238000001914 filtration Methods 0.000 claims abstract description 20
- 238000004519 manufacturing process Methods 0.000 claims abstract description 19
- 230000006978 adaptation Effects 0.000 claims abstract description 3
- 208000005156 Dehydration Diseases 0.000 claims description 29
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 16
- 230000000694 effects Effects 0.000 abstract description 7
- 238000000746 purification Methods 0.000 abstract description 7
- 238000011084 recovery Methods 0.000 abstract description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 239000012466 permeate Substances 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000012043 crude product Substances 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010612 desalination reaction Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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- External Artificial Organs (AREA)
- Filtration Of Liquid (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
The utility model discloses a heparin sodium apparatus for producing that dehydration rate is high relates to heparin sodium production technical field. This heparin sodium apparatus for producing that dehydration rate is high, including the extrusion storehouse, be equipped with extrusion dewatering device in the extrusion storehouse, extrusion dewatering device includes the pan feeding pipe, the lower fixed surface of pan feeding pipe is connected with the stripper plate, the groove with pan feeding pipe size looks adaptation is seted up to the upper surface of stripper plate, stripper plate swing joint has the extrusion groove, the extrusion groove has been seted up to the upper surface in extrusion storehouse, this heparin sodium apparatus for producing that dehydration rate is high, and water after through the extrusion gets into through the screw thread hollow tube after through the filtration of filter layer and collects the storehouse, accomplishes the back, twists and collects the storehouse, and the twisting that collects the storehouse drives the rotation of screw thread hollow tube, lets the screw thread hollow tube leave from the filter layer in, realizes the recovery to the water after breaking away from, and person's reutilization through secondary filter, has improved heparin sodium's purification effect greatly.
Description
Technical Field
The utility model relates to a heparin sodium production technical field specifically is a heparin sodium apparatus for producing that dehydration rate is high.
Background
The production of heparin sodium is carried out by a series of processes of enzymolysis, adsorption, washing, elution, precipitation, dehydration, desalination, drying and the like, wherein in order to improve the dehydration rate of the heparin sodium during dehydration, an ethanol solution with the mass percentage concentration of 95% is generally adopted, namely, the heparin sodium crude product is soaked and filtered for many times by using alcohol, and the water contained in the heparin sodium crude product is removed by utilizing the characteristic that the alcohol is mutually soluble with water and is insoluble with the heparin sodium.
Soaking and the general components of a whole that can function independently of filtration go on, have the leakproofness problem, not only can have volatilizing of alcohol, be unfavorable for the later stage to the recovery of alcohol, and the quality of heparin sodium is influenced in the entering of external impurity that also may have.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a heparin sodium apparatus for producing that dehydration rate is high to solve the problem that proposes in the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme: a heparin sodium production device with high dehydration rate comprises an extrusion bin, wherein an extrusion dehydration device is arranged in the extrusion bin, the extrusion dehydration device comprises a feeding pipe, the lower surface of the feeding pipe is fixedly connected with an extrusion plate, the upper surface of the extrusion plate is provided with a groove matched with the feeding pipe in size, the extrusion plate is movably connected with an extrusion groove, the upper surface of the extrusion bin is provided with an extrusion groove, the upper surface of the feeding pipe is provided with a feeding port, the feeding port is movably connected with a clamping column, and a movable cap is fixedly connected to the upper surface of the clamping column; a secondary dehydration device is arranged outside the extrusion bin; and a collecting device is arranged in the extrusion bin.
Preferably, the secondary dewatering device comprises a connecting pipe, the connecting pipe is fixedly connected to the lower surface of the extrusion bin, the extrusion bin is fixedly connected to the lower surface of the connecting pipe, the filter layer is fixedly connected to the lower surface of the extrusion bin, the threaded hollow pipe is movably connected to the lower surface of the filter layer, a groove matched with the threaded hollow pipe is formed in the lower surface of the filter layer, and the collection bin is fixedly connected to the lower surface of the threaded hollow pipe.
Preferably, collection device includes the pulling handle, the fixed frame of the back fixedly connected with of pulling handle, the following fixedly connected with filter screen of fixed frame, fixed frame swing joint has the shifting chute, the shifting chute has been seted up in the front in extrusion storehouse, fixed frame and shifting chute size looks adaptation.
Compared with the prior art, the beneficial effects of the utility model are that:
(1) the heparin sodium production device with high dehydration rate has the advantages that the movable cap moves upwards, the movable cap drives the clamping column to move, the clamping column moves upwards to enable the clamping column to leave from the feeding port, at this time, heparin sodium to be dehydrated is guided into the feeding pipe through the feeding port, the heparin sodium entering the feeding pipe enters the extrusion groove, at this time, the movable cap moves downwards to enable the clamping column to enter the feeding port newly, sealing of the heparin sodium production device is achieved, the heparin sodium production quality is prevented from being affected by the entering of other substances during dehydration, at this time, the feeding pipe moves downwards, the downward movement of the feeding pipe drives the extrusion plate to move downwards, the downward movement of the extrusion plate in the extrusion groove can generate pressure on the heparin sodium in the extrusion chamber, the heparin sodium moves downwards to be filtered through the filter screen, and water in the filter screen can move downwards, and heparin sodium can stay on the surface of filter screen, the result after being filtered can leave from the extrusion storehouse at this time, the result after leaving passes through in the connecting pipe gets into the extrusion bucket, the storehouse is collected in the rebound this time, the rebound in collection storehouse drives the rebound of filter layer, the rebound of filter layer extrudees the result in the extrusion bucket, water in the heparin sodium can be extruded once more, water after the extrusion passes through the filtration of filter layer after getting into the collection storehouse through the screw thread hollow tube, after the completion, the storehouse is collected in the wrench movement, the wrench movement in collection storehouse drives the rotation of screw thread hollow tube, let the screw thread hollow tube leave from the filter layer, realize the recovery to the water after breaking away from, person's of facilitating the use's reutilization, through secondary filtration, heparin sodium's purification effect has been improved greatly.
(2) This heparin sodium apparatus for producing that dehydration rate is high, through outside pulling handle, the removal of pulling handle drives the removal of fixed frame, fixed frame removes in the shifting chute, and when the pulling handle can prevent to dewater, the heparin sodium in the extrusion storehouse permeates out, improve the effect of purification, and the pulling handle leaves the back completely, draw out the heparin sodium on filter screen surface, realize the collection to heparin sodium, this device is through can removing the collection device, the person of facilitating the use is to the collection of heparin sodium, the collection speed of apparatus for producing has been improved.
Drawings
FIG. 1 is a schematic structural view of a heparin sodium production device with high dehydration rate;
FIG. 2 is an exploded view of the squeezing and dewatering device of the present invention;
FIG. 3 is an exploded view of the secondary dewatering device of the present invention;
fig. 4 is an exploded view of the collecting device of the present invention.
In the figure: 1 extrusion storehouse, 2 extrusion groove, 11 removal cap, 12 block post, 13 pan feeding mouths, 14 pan feeding pipes, 15 stripper plates, 21 connecting pipes, 22 extrusion bucket, 23 filter layer, 24 collection storehouse, 25 screw thread hollow tubes, 31 pulling handle, 32 moving groove, 33 fixed frame, 34 filter screen.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1-4, the present invention provides a technical solution: a heparin sodium production device with high dehydration rate comprises an extrusion bin 1, an extrusion dehydration device is arranged in the extrusion bin 1 and comprises a feeding pipe 14, the lower surface of the feeding pipe 14 is fixedly connected with an extrusion plate 15, the upper surface of the extrusion plate 15 is provided with a groove matched with the feeding pipe 14 in size, the extrusion plate 15 is movably connected with an extrusion groove 2, the upper surface of the extrusion bin 1 is provided with the extrusion groove 2, the upper surface of the feeding pipe 14 is provided with a feeding port 13, the feeding port 13 is internally movably connected with a clamping column 12, the upper surface of the clamping column 12 is fixedly connected with a movable cap 11, a secondary dehydration device is arranged outside the extrusion bin 1 and comprises a connecting pipe 21, the lower surface of the extrusion bin 1 is fixedly connected with a connecting pipe 21, the lower surface of the connecting pipe 21 is fixedly connected with an extrusion barrel 22, the lower surface of the extrusion barrel 22 is fixedly connected with a filter layer 23, the lower surface of the filter layer 23 is movably connected with a threaded hollow pipe 25, a groove matched with the threaded hollow tube 25 is formed below the filter layer 23, a collection bin 24 is fixedly connected below the threaded hollow tube 25, the moving cap 11 moves upwards, the moving cap 11 moves the clamping column 12, the clamping column 12 moves upwards to enable the clamping column 12 to leave from the feeding port 13, at this time, heparin sodium to be dehydrated is guided into the feeding tube 14 through the feeding port 13, the heparin sodium entering the feeding tube 14 enters the extrusion tank 2, at this time, the moving cap 11 moves downwards to enable the clamping column 12 to newly enter the feeding port 13, sealing of a heparin sodium production device is achieved, the heparin sodium production quality is prevented from being affected due to the entering of other substances during dehydration, at this time, the feeding tube 14 moves downwards, the downward movement of the feeding tube 14 drives the downward movement of the extrusion plate 15, the downward movement of the extrusion plate 15 in the extrusion tank 2 generates pressure on the heparin sodium in the extrusion bin 1, heparin sodium moves downwards to pass through the filtering of the filtering net 34, water in the filtering net 34 moves downwards, the heparin sodium remains on the surface of the filtering net 34, a filtered product leaves from the extrusion bin 1 at this time, the product after leaving enters the extrusion bin 22 through the connecting pipe 21, the collection bin 24 moves upwards at this time, the upward movement of the collection bin 24 drives the filtering layer 23 to move upwards, the upward movement of the filtering layer 23 extrudes the product in the extrusion bin 22, water in the heparin sodium is extruded again, the extruded water enters the collection bin 24 through the threaded hollow pipe 25 after being filtered by the filtering layer 23, after the completion, the collection bin 24 is twisted, the twisting of the collection bin 24 drives the threaded hollow pipe 25 to rotate, the threaded hollow pipe 25 leaves from the filtering layer 23, the recovery of the water after being separated is realized, and the secondary utilization of a user is facilitated, through secondary filtration, the purification effect of heparin sodium is greatly improved, a collecting device is arranged in the extrusion bin 1, the collecting device comprises a pulling handle 31, a fixed frame 33 is fixedly connected to the back of the pulling handle 31, a filter screen 34 is fixedly connected to the lower surface of the fixed frame 33, the fixed frame 33 is movably connected with a moving groove 32, the moving groove 32 is formed in the front surface of the extrusion bin 1, the fixed frame 33 is matched with the moving groove 32 in size, the pulling handle 31 is pulled outwards, the moving of the pulling handle 31 drives the fixed frame 33 to move, the fixed frame 33 moves in the moving groove 32, the pulling handle 31 can prevent dehydration, the heparin sodium in the extrusion bin 1 permeates out, the purification effect is improved, after the pulling handle 31 is completely separated, the heparin sodium on the surface of the filter screen 34 is extracted, the collection of the heparin sodium is realized, the collecting device can move, the convenience of a user collects the heparin sodium, and the collection speed of the production device is improved.
The working principle is as follows:
the first step is as follows: by moving the moving cap 11 upwards, the moving of the moving cap 11 drives the moving of the clamping column 12, the moving of the clamping column 12 causes the clamping column 12 to leave from the feeding port 13, at this time, heparin sodium to be dehydrated is guided into the feeding pipe 14 through the feeding port 13, the heparin sodium entering into the feeding pipe 14 enters into the extrusion tank 2, at this time, the moving cap 11 moves downwards, the clamping column 12 enters into the feeding port 13 newly, sealing of the heparin sodium production device is realized, the entering of other substances is prevented from influencing the production quality of the heparin sodium when dehydration is carried out, at this time, the feeding pipe 14 moves downwards, the downward movement of the feeding pipe 14 drives the downward movement of the extrusion plate 15, the downward movement of the extrusion plate 15 in the extrusion tank 2 generates pressure on the heparin sodium in the extrusion bin 1, the heparin sodium moves downwards to pass through the filtering of the filtering net 34, and the water in the filtering net 34 moves downwards, and heparin sodium can stay on the surface of filter screen 34, the product after being filtered can leave from extrusion storehouse 1 at this time, the product after leaving passes through connecting pipe 21 and gets into extrusion bucket 22 in, at this time upward movement collects storehouse 24, the upward movement of collecting storehouse 24 drives the upward movement of filter layer 23, the upward movement of filter layer 23 extrudees the product in extrusion bucket 22, water in the heparin sodium can be extruded once more, water after the extrusion passes through filter layer 23 and filters the back and gets into collection storehouse 24 through screw thread hollow tube 25, after the completion, twist and collect storehouse 24, the twist of collecting storehouse 24 drives the rotation of screw thread hollow tube 25, let screw thread hollow tube 25 leave from filter layer 23, realize the recovery of the water after breaking away from, convenience of customers's reutilization, through secondary filtration, heparin sodium's purification effect has been improved greatly.
The second step is that: through outside pulling handle 31, the removal of pulling handle 31 drives the removal of fixed frame 33, fixed frame 33 removes in shifting chute 32, and pulling handle 31 when can preventing the dehydration, the heparin sodium in the extrusion storehouse 1 permeates out, improve the effect of purification, and pulling handle 31 leaves the back completely, draw out the heparin sodium on filter screen 34 surface, realize the collection to heparin sodium, this device is through can removing the collection device, the person of facilitating the use is to the collection of heparin sodium, the collection speed of apparatus for producing has been improved.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. The utility model provides a heparin sodium apparatus for producing that dehydration rate is high, includes extrusion storehouse (1), be equipped with extrusion dewatering device in extrusion storehouse (1), its characterized in that: the extrusion dehydration device comprises a feeding pipe (14), wherein an extrusion plate (15) is fixedly connected to the lower surface of the feeding pipe (14), a groove matched with the feeding pipe (14) in size is formed in the upper surface of the extrusion plate (15), the extrusion plate (15) is movably connected with an extrusion groove (2), the extrusion groove (2) is formed in the upper surface of an extrusion bin (1), a feeding hole (13) is formed in the upper surface of the feeding pipe (14), a clamping column (12) is movably connected in the feeding hole (13), and a moving cap (11) is fixedly connected to the upper surface of the clamping column (12);
a secondary dehydration device is arranged outside the extrusion bin (1);
a collecting device is arranged in the extrusion bin (1).
2. The heparin sodium production device with high dehydration rate according to claim 1, which is characterized in that: the secondary dewatering device comprises a connecting pipe (21), and the connecting pipe (21) is fixedly connected below the extrusion bin (1).
3. The heparin sodium production device with high dehydration rate according to claim 2, which is characterized in that: the extrusion barrel (22) is fixedly connected below the connecting pipe (21), and the filtering layer (23) is fixedly connected below the extrusion barrel (22).
4. The heparin sodium production device with high dehydration rate according to claim 3, which is characterized in that: the lower part of the filtering layer (23) is movably connected with a threaded hollow pipe (25), a groove matched with the threaded hollow pipe (25) is formed in the lower part of the filtering layer (23), and a collecting bin (24) is fixedly connected to the lower part of the threaded hollow pipe (25).
5. The heparin sodium production device with high dehydration rate according to claim 1, which is characterized in that: the collecting device comprises a pulling handle (31), a fixed frame (33) is fixedly connected to the back of the pulling handle (31), and a filter screen (34) is fixedly connected to the lower face of the fixed frame (33).
6. The heparin sodium production device with high dehydration rate according to claim 5, which is characterized in that: fixed frame (33) swing joint has shifting chute (32), shifting chute (32) have been seted up in the front in extrusion storehouse (1), fixed frame (33) and shifting chute (32) size looks adaptation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023005874.6U CN214419671U (en) | 2020-12-11 | 2020-12-11 | Heparin sodium apparatus for producing that dehydration rate is high |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023005874.6U CN214419671U (en) | 2020-12-11 | 2020-12-11 | Heparin sodium apparatus for producing that dehydration rate is high |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214419671U true CN214419671U (en) | 2021-10-19 |
Family
ID=78051158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202023005874.6U Expired - Fee Related CN214419671U (en) | 2020-12-11 | 2020-12-11 | Heparin sodium apparatus for producing that dehydration rate is high |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214419671U (en) |
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2020
- 2020-12-11 CN CN202023005874.6U patent/CN214419671U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20211019 |