CN214371438U

CN214371438U - Fmoc amino acid drying device

Info

Publication number: CN214371438U
Application number: CN202023234883.2U
Authority: CN
Inventors: 徐洪岩; 朱小兴; 范成龙; 吕强军; 徐钊; 林崔建; 杨明
Original assignee: Nanjing Peptide Biotechnology Co ltd
Current assignee: Nanjing Peptide Biotechnology Co ltd
Priority date: 2020-12-29
Filing date: 2020-12-29
Publication date: 2021-10-08
Anticipated expiration: 2030-12-29

Abstract

The utility model provides an Fmoc amino acid drying device, which comprises a drying support frame seat, wherein a drying bin is arranged on the drying support frame seat; the drying bin is provided with a sealing door, and the bottom of the drying bin is fixedly connected with the air heater through a telescopic air inlet hose; wherein the air inlet of the air heater is connected with a gas dust removal filter device; wherein the flexible soft air inlet pipe is fixedly connected with the air distributor in the drying bin; wherein, two ends of the inner bin of the drying bin are provided with rotating frames; each rotating frame is fixedly connected with an output shaft of a fixed positive and negative rotating motor; limiting plates are arranged at the front end and the rear end of the output shaft; wherein the drying bin is provided with a limit switch matched with the limit plate; the two ends of the bearing box are fixed at the bottom in the rotating frame in a sliding way, and a plurality of air inlets are arranged at the bottom in the rotating frame; wherein the top of the drying bin is provided with an air outlet pipe. The Fmoc detection kit is thorough in drying, convenient to clean and capable of ensuring clean washing when being used for detecting that no Fmoc residue exists.

Description

Fmoc amino acid drying device

Technical Field

The utility model relates to an amino acid drying process field especially relates to a Fmoc amino acid drying device.

Background

Protecting groups are groups which are protected before the reaction and which are recovered after the reaction is completed, in order to allow the reaction to take place only at the desired group and to avoid the influence of other groups when the reaction of the organic compound with a multifunctional group is carried out. An agent capable of protecting a certain group is referred to as a protecting group of the group. The use of protecting groups in organic reactions is common, and the protecting groups are commonly used for protecting groups such as hydroxyl, amino and the like; many biologically active molecules contain amino groups, and therefore protection of the amino group is important in drug synthesis. At present, the Fmoc amino acid drying device is unreasonable in design, incomplete in drying and difficult to detect whether the Fmoc amino acid drying device is thoroughly cleaned or not.

Disclosure of Invention

In order to solve the problems, the invention discloses an Fmoc amino acid drying device which comprises a drying support frame seat, wherein a drying bin is arranged on the drying support frame seat; the drying bin is provided with a sealing door, and the bottom of the drying bin is fixedly connected with the air heater through a telescopic air inlet hose; wherein the air inlet of the air heater is connected with a gas dust removal filter device; wherein the flexible soft air inlet pipe is fixedly connected with the air distributor in the drying bin; wherein, two ends of the inner bin of the drying bin are provided with rotating frames; each rotating frame is fixedly connected with an output shaft of a fixed positive and negative rotating motor; limiting plates are arranged at the front end and the rear end of the output shaft; wherein the drying bin is provided with a limit switch matched with the limit plate; the two ends of the bearing box are fixed at the bottom in the rotating frame in a sliding way, and a plurality of air inlets are arranged at the bottom in the rotating frame; wherein the top of the drying bin is provided with an air outlet pipe.

The utility model discloses the further improvement lies in: the air outlet pipe is fixedly connected with the bag-type dust remover and can filter the gas in the drying bin, and the filtered dry substances are filtered by the bag of the bag-type dust remover and finally collected through the discharge port of the bag-type dust remover.

The utility model discloses the further improvement lies in: and the air outlet pipe is provided with a flow regulating valve for controlling the flow of the air outlet.

The utility model discloses the further improvement lies in: wherein the top of the drying bin is provided with a water tank; wherein, the water outlet of the water tank is fixedly connected with a cleaning pipe in the drying bin, and a plurality of water outlets are arranged on the cleaning pipe; a water outlet valve is arranged at the bottom of the drying bin; and an ultraviolet detector is arranged on the inner wall of the drying bin.

The utility model discloses the further improvement lies in: the front end and the rear end of the rotating frame are rotatably provided with baffles, so that the bearing box is limited and prevented from sliding off.

The utility model discloses the during operation: 1. firstly, opening a sealing door, putting materials into a bearing box, then closing the sealing door, filtering dust and impurities in heated gas through a dust removal filtering device, heating the gas through a hot air blower, and finally sending the heated gas into a drying bin through a telescopic air inlet hose; the gas distributor can ensure that the heated and dried gas is uniformly delivered into the drying bin and the product in the bearing box is dried through the gas inlet;

2. meanwhile, the limiting plate is matched with the limiting switch, so that the forward and reverse rotating motor drives the rotating frame to swing back and forth in a small amplitude, and thorough and uniform drying is guaranteed.

3. After the drying is finished, the sealing door is opened, the bearing box is slidably discharged, dried products are collected, the bearing box is conveyed into the rotating frame after the collection is finished, the bearing box is blocked by the baffle plate, the sealing door is closed again, cleaning water is conveyed into the cleaning pipe by the water in the water tank, the drying bin is cleaned, the water outlet valve is opened at last to discharge the wastewater, the water outlet valve is opened at last to discharge, and due to the fact that the ultraviolet absorption detector is arranged, due to the fact that Fmoc has strong ultraviolet absorption, the Fmoc residue is detected, the cleaning is convenient, and the cleaning is guaranteed.

Drawings

FIG. 1 is a schematic structural view of the present invention;

fig. 2, a perspective view of the present invention;

list of reference numerals:

wherein 1-drying the supporting seat; 2-drying the bin; 3-sealing the door; 4-telescopic air inlet hose; 5-a hot air blower; 6-a dust removal filter device; 7-a gas distributor; 8-rotating the frame; 9-a positive and negative rotation motor; 10-a limiting plate; 11-limit switches; 12-a carrying case; 13-an air intake; 14-an air outlet pipe; 15-bag dust collector; 16-a flow regulating valve; 17-a water tank; 18-a cleaning tube; 19-a water outlet valve; 20-an ultraviolet detector; 21-baffle.

Detailed Description

The present invention will be further illustrated with reference to the accompanying drawings and specific embodiments, which are to be understood as merely illustrative of the invention and not as limiting the scope of the invention. It should be noted that the terms "front," "back," "left," "right," "upper" and "lower" used in the following description refer to directions in the drawings, and the terms "inner" and "outer" refer to directions toward and away from, respectively, the geometric center of a particular component.

As shown in fig. 1-2, the Fmoc amino acid drying device of this embodiment includes a drying support base 1, wherein a drying bin 2 is disposed on the drying support base 1; a sealing door 3 is arranged on the drying bin 2, and the bottom of the drying bin is connected and fixed with an air heater 5 through a telescopic air inlet hose 4; wherein the air inlet of the air heater 5 is connected with an air dust removal filter device 6; wherein the flexible soft air inlet pipe 4 is fixedly connected with the air distributor 7 in the drying bin 2; wherein, two ends of the inner bin of the drying bin 2 are provided with rotating frames 8; each rotating frame 8 is fixedly connected with an output shaft of a fixed positive and negative rotating motor 9; wherein, the front end and the rear end of the output shaft are provided with limit plates 10; the drying bin 2 is provided with a limit switch 11 matched with the limit plate 10; the bottom of the two ends of the bearing box 12 fixed in the rotating frame 8 in a sliding way is provided with a plurality of air inlet holes 13; the front end and the rear end of the rotating frame 8 are rotatably provided with baffles 21.

Wherein the top of the drying bin 2 is provided with an air outlet pipe 14; and the air outlet pipe 14 is provided with a flow regulating valve 16 and is fixedly connected with a bag-type dust collector 15.

Firstly, opening a sealing door 3, putting materials into a bearing box 12, then closing the sealing door 3, filtering dust and impurities in heated gas through a dust removal filtering device 6, and then heating through a hot air blower 5; finally, the mixture is sent into a drying bin through a telescopic air inlet hose 4; the gas distributor 7 can ensure that the heated and dried gas is uniformly delivered into the drying bin 2 and the product in the bearing box 12 is dried through the gas inlet; meanwhile, the limiting plate 10 and the limiting switch 11 are matched with each other, so that the forward and reverse rotating motor 9 drives the rotating frame 8 to swing back and forth in a small amplitude, and thorough and uniform drying is guaranteed.

Wherein the top of the drying bin 2 is provided with a water tank 17; wherein, the water outlet of the water tank 17 is fixedly connected with a cleaning pipe 18 in the drying bin 2, and a plurality of water outlets are arranged on the cleaning pipe 18; a water outlet valve 19 is arranged at the bottom of the drying bin 2; an ultraviolet detector 20 is arranged on the inner wall of the drying bin 2; after the drying is finished, the sealing door 3 is opened, the bearing box 12 is discharged in a sliding mode, dried products are collected, after the collection is finished, the bearing box 12 is sent into the rotating frame 8, the baffle is used for blocking, the sealing door 3 is closed again, water in the water tank 17 is used for sending cleaning water into the cleaning pipe 18, the drying bin 2 is cleaned, the water outlet valve 19 is opened finally to discharge waste water, the water outlet valve 19 is opened finally to discharge the waste water, and due to the fact that the ultraviolet absorption detector 20 is arranged, due to the fact that Fmoc has strong ultraviolet absorption, the Fmoc detection device is used for detecting that no Fmoc residue exists, cleaning is convenient, and cleaning is guaranteed to be clean.

The technical means disclosed in the invention scheme are not limited to the technical means disclosed in the above embodiments, but also include the technical scheme formed by any combination of the above technical features.

Claims

1. The Fmoc amino acid drying device is characterized in that: the drying device comprises a drying support frame seat (1), wherein a drying bin (2) is arranged on the drying support frame seat (1); a sealing door (3) is arranged on the drying bin (2), and the bottom of the drying bin is fixedly connected with an air heater (5) through a telescopic air inlet hose (4); wherein the air inlet of the hot air blower (5) is connected with an air dust removal filtering device (6); wherein the telescopic air inlet hose (4) is fixedly connected with an air distributor (7) in the drying bin (2); wherein, two ends of the inner chamber of the drying chamber (2) are provided with rotating frames (8); each rotating frame (8) is fixedly connected with an output shaft of a fixed positive and negative rotating motor (9); wherein, the front end and the rear end of the output shaft are provided with limit plates (10); wherein the drying bin (2) is provided with a limit switch (11) matched with the limit plate (10); the two ends of the bearing box (12) are fixed at the bottom in the rotating frame (8) in a sliding way, and a plurality of air inlets (13) are arranged at the bottom; wherein the top of the drying bin (2) is provided with an air outlet pipe (14).

2. The Fmoc amino acid drying device of claim 1, wherein: the air outlet pipe (14) is fixedly connected with the bag-type dust collector (15).

3. The Fmoc amino acid drying device of claim 1, wherein: and a flow regulating valve (16) is arranged on the air outlet pipe (14).

4. The Fmoc amino acid drying device of claim 1, wherein: wherein the top of the drying bin (2) is provided with a water tank (17); wherein the water outlet of the water tank (17) is fixedly connected with a cleaning pipe (18) in the drying bin (2), and a plurality of water outlets are arranged on the cleaning pipe (18); a water outlet valve (19) is arranged at the bottom of the drying bin (2); and an ultraviolet detector (20) is arranged on the inner wall of the drying bin (2).

5. The Fmoc amino acid drying device of claim 1, wherein: the front end and the rear end of the rotating frame (8) are rotatably provided with baffles (21).