CN214299956U - Membrane processing method chick embryo antigen concentrator - Google Patents
Membrane processing method chick embryo antigen concentrator Download PDFInfo
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- CN214299956U CN214299956U CN202023063903.4U CN202023063903U CN214299956U CN 214299956 U CN214299956 U CN 214299956U CN 202023063903 U CN202023063903 U CN 202023063903U CN 214299956 U CN214299956 U CN 214299956U
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- chamber
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- mounting
- concentrator
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- 239000012528 membrane Substances 0.000 title claims abstract description 27
- 239000000427 antigen Substances 0.000 title claims abstract description 22
- 102000036639 antigens Human genes 0.000 title claims abstract description 22
- 108091007433 antigens Proteins 0.000 title claims abstract description 22
- 238000003672 processing method Methods 0.000 title claims abstract description 9
- 210000003837 chick embryo Anatomy 0.000 title abstract description 8
- 238000001914 filtration Methods 0.000 claims abstract description 16
- 239000007788 liquid Substances 0.000 claims description 20
- 238000000605 extraction Methods 0.000 claims description 18
- 241000287828 Gallus gallus Species 0.000 claims 4
- 210000001161 mammalian embryo Anatomy 0.000 claims 4
- 239000012535 impurity Substances 0.000 abstract description 12
- 238000005119 centrifugation Methods 0.000 abstract description 3
- 230000000694 effects Effects 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract description 2
- 239000000126 substance Substances 0.000 description 6
- 238000000746 purification Methods 0.000 description 5
- 238000007789 sealing Methods 0.000 description 5
- 210000001744 T-lymphocyte Anatomy 0.000 description 3
- 210000003719 b-lymphocyte Anatomy 0.000 description 3
- 230000028993 immune response Effects 0.000 description 3
- 230000005847 immunogenicity Effects 0.000 description 3
- 210000004698 lymphocyte Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- QCVGEOXPDFCNHA-UHFFFAOYSA-N 5,5-dimethyl-2,4-dioxo-1,3-oxazolidine-3-carboxamide Chemical compound CC1(C)OC(=O)N(C(N)=O)C1=O QCVGEOXPDFCNHA-UHFFFAOYSA-N 0.000 description 1
- 102000006306 Antigen Receptors Human genes 0.000 description 1
- 108010083359 Antigen Receptors Proteins 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000009739 binding Methods 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 235000014103 egg white Nutrition 0.000 description 1
- 210000000969 egg white Anatomy 0.000 description 1
- 210000002969 egg yolk Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000012642 immune effector Substances 0.000 description 1
- 229940121354 immunomodulator Drugs 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Images
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model relates to a relevant technical field of bacterin cultivation, specifically be a membrane processing method chick embryo antigen concentrator, including drawing the chamber and setting up the pressurized cavity at drawing the chamber upside, it draws the chamber for fixed mounting on the lower side cradling piece of support, fixed mounting has hydraulic assembly on the upper side cradling piece of support, there is a mounting panel through connecting piece fixed mounting on its hydraulic assembly's the telescopic link, the downside of mounting panel is provided with the connecting rod, the connecting rod is L-shaped pole body, and its body of rod is provided with four altogether, and the lower extreme fixed connection of its body of rod is on the cavity lateral wall of pressurized cavity, the central point of mounting panel lower surface puts fixed mounting has flexible electric jar, be provided with the piston in the inner chamber of pressurized cavity; through setting up tubular structure draw chamber and pressure boost chamber to set up filtration membrane in drawing the inner chamber in chamber, thereby filter the impurity in the stoste through filtration membrane's effect, thereby avoid material mass fraction to be close with impurity mass fraction and adopt the centrifugation to get rid of the emergence of impurity failure.
Description
Technical Field
The utility model relates to a relevant technical field of bacterin cultivation specifically is a membrane processing method chick embryo antigen concentrator.
Background
Antigen (Ag) refers to all substances that induce an immune response in the body. Namely, a substance which can be specifically recognized and bound by an antigen receptor (TCR/BCR) on the surface of a T/B lymphocyte, activates the T/B lymphocyte, proliferates and differentiates the T/B lymphocyte, generates an immune response product (sensitized lymphocyte or antibody), and can be specifically bound with the corresponding product in vitro and in vivo. Thus, antigenic substances possess two important properties: immunogenicity (immunogenicity) and immunoreactivity (immunoreactivity). Immunogenicity refers to the ability of an antigen to induce an organism to generate a specific immune response, produce antibodies and/or sensitize lymphocytes; immunoreactivity refers to the ability to undergo specific binding reactions with corresponding immune effector substances (antibodies or sensitized lymphocytes) in vitro and in vivo; however, the antigen liquid after the antigen is harvested contains a certain amount of yolk liquid and egg white liquid, so that the concentration and purification are required, but the traditional purification device adopts centrifugation to remove impurities, and the centrifugation sometimes fails to remove the impurities because the mass fraction of substances is similar to that of the impurities; therefore, the utility model provides a membrane processing method chick embryo antigen concentrator is used for solving above-mentioned problem.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a membrane processing method chick embryo antigen concentrator to solve the problem that proposes in the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme: a membrane processing method chick embryo antigen concentrator comprises an extraction cavity and a pressurizing cavity arranged on the upper side of the extraction cavity, wherein the extraction cavity is fixedly arranged on a lower side bracket rod of a bracket, a hydraulic assembly is fixedly arranged on an upper side bracket rod of the bracket, a mounting plate is fixedly arranged on a telescopic rod of the hydraulic assembly through a connecting piece, a connecting rod is arranged on the lower side surface of the mounting plate, the connecting rod is an L-shaped rod body, four rod bodies are arranged on the rod body, the lower end of the rod body is fixedly connected to the side wall of the cavity of the pressurizing cavity, a telescopic electric cylinder is fixedly arranged at the central position of the lower surface of the mounting plate, a piston is arranged in the inner cavity of the pressurizing cavity, a connecting plate is fixedly connected to the upper surface of the piston, the upper surface of the connecting plate is connected with the telescopic rod of the telescopic electric cylinder through the connecting piece, the extraction cavity is a round tube, and the size of the extraction cavity is identical to that of the pressurizing cavity, and seted up the mounting groove on its lower extreme inner chamber lateral wall, and seted up on the lateral wall of its mounting groove and have the internal thread structure, and have filtration membrane through mounting fixed mounting in its notch, it is provided with the inlet fluid pipeline on the lateral wall to draw the chamber upper end, and connects on its pipeline and install solenoid valve for liquid, be provided with the admission line on the lower extreme lateral wall in pressure boost chamber, and connect on its pipeline and install solenoid valve for gas.
Preferably, the mounting is a round pipe, the outer diameter of the pipe body of the mounting is identical to the diameter of the mounting groove in the extraction cavity, external threads are formed in the outer side wall of the pipe body of the mounting, the pipe body of the mounting is fixed and screwed on internal threads on the side wall of the mounting groove through the external threads, a rubber gasket is arranged at the uppermost end of the mounting, and the filtering membrane is fixedly clamped between the mounting groove and the rubber gasket.
Preferably, the side is gone up to the body that draws the chamber fixed mounting has first seal ring, fixed mounting has second seal ring on the body downside of pressure boost chamber, first seal ring, second seal ring are corresponding setting.
Preferably, when the telescopic electric cylinder moves up and down, the moving range of the piston is positioned between the upper side of the air inlet pipeline and the upper end surface of the pressurizing cavity, and the liquid level of the antigen liquid to be extracted in the extracting cavity is lower than that of the liquid inlet pipeline.
Compared with the prior art, the beneficial effects of the utility model are that:
1. the extraction cavity and the pressurization cavity which are of tubular structures are arranged, and the filtering membrane is arranged in the inner cavity of the extraction cavity, so that impurities in the stock solution are filtered under the action of the filtering membrane, and the failure of removing the impurities by adopting a centrifugal method due to the fact that the mass fraction of the substances is close to that of the impurities is avoided;
2. the air inlet pipeline is arranged on the pressurizing cavity, so that the pressurizing cavity is pressurized through the air inlet pipeline, the piston is arranged in the inner cavity of the pressurizing cavity, and the piston is continuously driven up and down through the telescopic electric cylinder, so that the pressure in the extracting cavity and the pressurizing cavity is continuously changed, and the aim of improving the purification efficiency of the extracting cavity and the pressurizing cavity is fulfilled.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a semi-sectional view of the extraction chamber and the pressurizing chamber of the present invention;
FIG. 3 is an enlarged view of the structure at A in FIG. 2;
FIG. 4 is an enlarged view of the structure at B in FIG. 2;
fig. 5 is an enlarged view of the structure at C in fig. 2.
In the figure: draw chamber 1, pressure boost chamber 2, support 3, hydraulic assembly 4, mounting panel 5, connecting rod 6, flexible electric jar 7, piston 8, connecting plate 9, mounting 10, rubber packing ring 11, filtration membrane 12, inlet pipe 13, inlet pipe 14, first seal ring 15, second seal ring 16.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1-5, the present invention provides a technical solution: a membrane processing method chick embryo antigen concentrator comprises an extraction cavity 1 and a pressurizing cavity 2 arranged on the upper side of the extraction cavity 1, wherein the extraction cavity 1 is fixedly arranged on a bracket rod on the lower side of a bracket 3, a hydraulic component 4 is fixedly arranged on the bracket rod on the upper side of the bracket 3, a mounting plate 5 is fixedly arranged on a telescopic rod of the hydraulic component through a connecting piece, a connecting rod 6 is arranged on the lower side surface of the mounting plate 5, the connecting rod 6 is an L-shaped rod body, four rod bodies are arranged on the upper side of the bracket rod body, the lower end of the rod body is fixedly connected to the side wall of a cavity body of the pressurizing cavity 2, a telescopic electric cylinder 7 is fixedly arranged at the central position of the lower surface of the mounting plate 5, a piston 8 is arranged in the inner cavity of the pressurizing cavity 2, a connecting plate 9 is fixedly connected to the upper surface of the piston 8, the upper surface of the connecting plate 9 is connected with the telescopic rod of the telescopic electric cylinder 7 through the connecting piece, the extraction cavity 1 is a round pipe, and the size of the extraction cavity 1 is matched with the size of the pressurizing cavity 2, and set up the mounting groove on its lower extreme inner chamber lateral wall, and set up the internal thread structure on the lateral wall of its mounting groove, and there is filtration membrane 12 through mounting 10 fixed mounting in its notch, it is provided with inlet channel 13 on the lateral wall of the upper end of drawing chamber 1, and connect on its pipeline and install the solenoid valve for liquid, be provided with admission line 14 on the lower extreme lateral wall of pressure boost chamber 2, and connect on its pipeline and install the solenoid valve for gas, draw chamber 1 and pressure boost chamber 2 through setting up the tubular structure, and set up filtration membrane 12 in drawing the inner chamber of chamber 1, thereby filter the impurity in the stoste through the effect of filtration membrane 12, thereby avoid the material mass fraction to be close with the impurity mass fraction and adopt the emergence that the centrifugal process got rid of impurity failure.
Further, the fixing member 10 is a circular tube, the outer diameter of the tube body is matched with the diameter of the mounting groove on the extraction cavity 1, the outer side wall of the tube body of the fixing member 10 is provided with an external thread, the tube body is fixedly screwed on the internal thread on the side wall of the mounting groove through the external thread, the uppermost end of the fixing member 10 is provided with a rubber gasket 11, and the filtering membrane 12 is fixedly clamped between the mounting groove and the rubber gasket 11;
furthermore, a first sealing washer 15 is fixedly arranged on the upper side surface of the tube body of the extraction cavity 1, a second sealing washer 16 is fixedly arranged on the lower side surface of the tube body of the pressurization cavity 2, the first sealing washer 15 and the second sealing washer 16 are arranged correspondingly to ensure the sealing property between the extraction cavity 1 and the pressurization cavity 2, and a barometer is arranged close to the lower side of the cavity body of the pressurization cavity 2 and is in electric signal connection with the PLC control module;
further, when the telescopic electric cylinder 7 moves up and down, the moving range of the piston 8 is positioned between the upper side of the air inlet pipeline 14 and the upper end surface of the pressurizing cavity 2, the liquid level of the antigen liquid to be extracted in the extracting cavity 1 is lower than that of the liquid inlet pipeline 13, the air inlet pipeline 14 is arranged on the pressurizing cavity 2, so that the pressurizing cavity 2 is pressurized through the air inlet pipeline 14, the piston 8 is arranged in the inner cavity of the pressurizing cavity 2, and the piston is continuously driven up and down through the telescopic electric cylinder 7, so that the pressure in the extracting cavity 1 and the pressurizing cavity 2 is continuously changed, and the purpose of improving the purification efficiency of the extracting cavity is achieved;
the working principle is as follows: when the device is actually used, a worker unloads the fixing piece 10 and the filtering membrane 12, then washes the extracting cavity 1, washes the fixing piece 10, replaces the filtering membrane 12, then installs the filtering piece, then drives the hydraulic component 4 to move in a process, so as to drive the pressurizing cavity 2 to press downwards, so that the pressurizing cavity 2 and the extracting cavity 1 are combined into a cavity structure, then the worker opens the electromagnetic valve for liquid, adds a proper amount of antigen liquid into the extracting cavity 1 through the liquid inlet pipeline 13, then closes the electromagnetic valve for liquid, then fills a proper amount of clean air into the pressurizing cavity 2 through opening the electromagnetic valve for gas, when the air pressure in the pressurizing cavity 2 reaches a proper value, closes the electromagnetic valve for gas, then drives the telescopic electric cylinder 7 to move in a continuous process and a continuous return stroke, so as to continuously pressurize the antigen liquid in the extracting cavity 1, thereby effectively improving the purification efficiency of the antigen liquid.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (4)
1. The utility model provides a membrane processing method chicken embryo antigen concentrator, is drawing chamber (1) and setting up pressure boost chamber (2) of drawing chamber (1) upside including drawing, and it draws chamber (1) for fixed mounting on the downside cradling piece of support (3), its characterized in that: the hydraulic support is characterized in that a hydraulic component (4) is fixedly mounted on an upper side support rod of the support (3), a mounting plate (5) is fixedly mounted on a telescopic rod of the hydraulic component through a connecting piece, a connecting rod (6) is arranged on the lower side surface of the mounting plate (5), the connecting rod (6) is an L-shaped rod body, four rod bodies are arranged on the telescopic rod of the hydraulic component, the lower end of each rod body is fixedly connected to the side wall of the cavity of the pressurizing cavity (2), a telescopic electric cylinder (7) is fixedly mounted at the central position of the lower surface of the mounting plate (5), a piston (8) is arranged in the inner cavity of the pressurizing cavity (2), a connecting plate (9) is fixedly connected to the upper surface of the piston (8), the upper surface of the connecting plate (9) is connected with the telescopic rod of the telescopic electric cylinder (7) through the connecting piece, the extracting cavity (1) is a section of a circular tube, and the size of the extracting cavity (1) is identical to that of the pressurizing cavity (2), and seted up the mounting groove on its lower extreme inner chamber lateral wall, and seted up on the lateral wall of its mounting groove and had internal thread structure, and there is filtration membrane (12) through mounting (10) fixed mounting in its notch, it is provided with inlet channel (13) on the lateral wall of chamber (1) upper end to draw, and connects on its pipeline and install solenoid valve for liquid, be provided with admission line (14) on the lower extreme lateral wall of pressure boost chamber (2), and connect on its pipeline and install solenoid valve for gas.
2. The membrane treatment chicken embryo antigen concentrator of claim 1, wherein: the fixing piece (10) is a round pipe, the outer diameter of the pipe body of the fixing piece is matched with the diameter of the mounting groove in the extraction cavity (1), external threads are arranged on the outer side wall of the pipe body of the fixing piece (10), the pipe body of the fixing piece is fixed and screwed on internal threads on the side wall of the mounting groove through the external threads, the rubber gasket (11) is arranged at the uppermost end of the fixing piece (10), and the filtering membrane (12) is fixedly clamped between the mounting groove and the rubber gasket (11).
3. The membrane treatment chicken embryo antigen concentrator of claim 1, wherein: draw on the body of chamber (1) fixed mounting have first seal ring (15) on the side, fixed mounting has second seal ring (16) on the body downside of pressure boost chamber (2), first seal ring (15), second seal ring (16) are corresponding setting.
4. The membrane treatment chicken embryo antigen concentrator of claim 1, wherein: when flexible electric jar (7) reciprocated, the moving range of piston (8) is located between admission line (14) upside and booster chamber (2) up end, and draws the liquid level height that waits to draw antigen liquid in chamber (1) and is less than inlet channel (13).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023063903.4U CN214299956U (en) | 2020-12-18 | 2020-12-18 | Membrane processing method chick embryo antigen concentrator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202023063903.4U CN214299956U (en) | 2020-12-18 | 2020-12-18 | Membrane processing method chick embryo antigen concentrator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN214299956U true CN214299956U (en) | 2021-09-28 |
Family
ID=77858596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202023063903.4U Active CN214299956U (en) | 2020-12-18 | 2020-12-18 | Membrane processing method chick embryo antigen concentrator |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN214299956U (en) |
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2020
- 2020-12-18 CN CN202023063903.4U patent/CN214299956U/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address |
Address after: No. 85 Keyun Road, High tech Zone, Qingdao, Shandong Province, 266000 Patentee after: Qingdao Blue Animal Health Group Co.,Ltd. Address before: 266000 north section of MaoYuan Road, high tech Zone, Qingdao, Shandong Patentee before: QINGDAO VLAND BIOTECH GROUP CO.,LTD. |
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| CP03 | Change of name, title or address |