CN214234094U

CN214234094U - Nanofluidic devices

Info

Publication number: CN214234094U
Application number: CN202023344296.9U
Authority: CN
Inventors: 廖洪钢; 林国林
Original assignee: Xiamen Super New Core Technology Co ltd
Current assignee: Xiamen Super New Core Technology Co ltd
Priority date: 2020-12-31
Filing date: 2020-12-31
Publication date: 2021-09-21
Anticipated expiration: 2030-12-31

Abstract

The utility model belongs to the technical field of in-situ experimental apparatus, in particular to a nanofluidic device, which comprises a shell, wherein a fluid control component and a controller are arranged in the shell, and the output end of the controller is connected with the control input end of the fluid control component; the fluid control assembly is provided with a flow passage switching valve, an injector and a plurality of internal flow passage interfaces, and the flow passage switching valve is used for switching the internal flow passage interfaces communicated with the injector; the shell is provided with a plurality of external flow passage interfaces, and different internal flow passage interfaces are respectively connected with different external flow passage interfaces. Different external flow passage interfaces can be used for receiving different fluid materials, and the different fluid materials are switched through the fluid control assembly; the fluid control assembly can suck and discharge fluid to make the fluid reciprocate in the chip. The control of the fluid flow, the switching of the materials and the reciprocating motion of the fluid in the chip are automatically completed by the fluid control assembly under the control of the controller, and the complicated manual operation of an operator is not needed.

Description

Nanofluidic devices

Technical Field

The utility model belongs to the technical field of normal position experimental apparatus, concretely relates to receive flow control device.

Background

In-situ fluid chips are used for experiments in which a fluid (gas or liquid) is introduced into the chip in real time to observe real-time physical or chemical changes. Since the space inside the fluid chip needs to be very thin to form a very thin fluid layer, and the electron transmission electron microscope can observe the fluid layer (too thick fluid layer can block the penetration of electron beams), the flow rate of the fluid needs to be very small (reaching nanoliter level).

Experimental procedures often require switching between multiple fluid materials. Certain experiments require that fluids be able to shuttle inside the chip, depending on the chip usage. At present, the control of fluid flow, the switching of materials and the reciprocating motion of fluid in a chip require complicated manual operation, switching and the like of an operator, which is very inconvenient.

SUMMERY OF THE UTILITY MODEL

In order to solve the above problems, the present invention provides a nanofluidic device capable of automatically controlling fluid flow, switching materials and controlling fluid movement direction.

Specifically, the technical scheme of the utility model is:

a nano-flow control device comprises a shell, wherein a fluid control assembly and a controller are arranged in the shell, and the output end of the controller is connected with the control input end of the fluid control assembly; the fluid control assembly is provided with a flow passage switching valve, an injector and a plurality of internal flow passage interfaces, and the flow passage switching valve is used for switching the internal flow passage interfaces communicated with the injector; the shell is provided with a plurality of external flow passage interfaces, and different internal flow passage interfaces are respectively connected with different external flow passage interfaces.

Preferably, the fluid control assembly further comprises a driving mechanism, the injector comprises a fluid container and a piston push rod, the control input ends of the piston push rod and the flow passage switching valve are connected with the output end of the driving mechanism, and the driving mechanism is connected with the control output end of the controller.

Preferably, the driving mechanism comprises a flow channel switching servo motor, a linear module, a planetary reducer and a linear module servo motor; the runner switching servo motor is connected with the runner switching valve and used for driving the runner switching valve to switch runners; the piston push rod is connected with the linear module servo motor through the linear module and the planetary reducer in sequence.

Preferably, the fluid container is a cylindrical glass tube.

Preferably, a touch screen assembly is arranged on the shell and connected with the controller.

Preferably, the number of the external runner interfaces and the internal runner interfaces is 6; of the 6 external flow joints, 1 was used as a waste outlet and the remaining 5 were used to connect experimental fluids or fluid rods, respectively.

Preferably, the top surface outside of shell is equipped with the fixed part, and the fixed part is used for connecting the cantilever beam.

Preferably, a handle is arranged on the outer side of the bottom surface of the shell.

Preferably, the external flow passage port is provided on an outer side surface of the housing.

Preferably, the inner flow passage interface is connected to the outer flow passage interface through a teflon pipe.

After adopting above-mentioned scheme, beneficial effect is:

under the control of the fluid control assembly, the fluid is output through the external flow channel interface according to the flow and the speed indicated by the control signal provided by the controller, reaches the fluid rod and enters the chip; different external flow passage interfaces can be used for receiving different fluid materials, and the different fluid materials are switched through the fluid control assembly; the fluid control assembly can suck and discharge fluid to make the fluid reciprocate in the chip. The control of fluid flow, the switching of materials and the round-trip action of fluid in the chip are automatically completed under the control of the controller by the fluid control assembly, an operator is not required to perform complicated manual operation, the use is more convenient and faster, the efficiency is higher, and the user experience is improved.

Drawings

Fig. 1 is a perspective structural view of a first embodiment of the present invention;

fig. 2 is an exploded structural view of a first embodiment of the present invention;

FIG. 3 is a diagram of a core portion of an embodiment of the present invention;

FIG. 4 is a block diagram of a fluid control assembly according to an embodiment of the present invention;

fig. 5 is a structural diagram of another view angle of a fluid control assembly according to an embodiment of the present invention.

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.

The first embodiment is as follows:

as shown in fig. 1 to 5, a nanofluidic device includes a housing 1, a fluid control module 2 and a controller 3 are disposed in the housing 1, and an output of the controller 3 is connected to a control input of the fluid control module 2. The Controller 3 may be an existing PLC (Programmable Logic Controller).

The fluid control assembly 2 has a flow switching valve 23, an injector 22 and a plurality of internal flow interfaces 21. The flow passage switching valve 23 is used to switch the internal flow passage interface 21 communicating with the syringe 22: the internal rotational switching action of the flow switching valve 23 is controlled by a control signal provided by the controller 3 to cause fluid to flow into or out of a particular internal flow port 21.

The housing 1 is provided with a plurality of external flow channel connectors 11, and different internal flow channel connectors 21 are respectively connected with different external flow channel connectors 11.

Further, in the present embodiment, the number of the outer fluid passage ports 11 and the number of the inner fluid passage ports 21 are both 6. Of the 6 external

flow passage interfaces

11, 1 external flow passage interface 11 is used as a waste discharge port and can be externally connected with a waste container to collect experimental waste; the other 5 external flow channel interfaces 11 are respectively used for connecting an experimental fluid (gas or liquid) or a fluid rod (the fluid reaches the chip through the fluid rod to participate in the experiment) to the outside, and taking gas as an example, 4 external flow channel interfaces can be used for air intake, 1 external flow channel interface can be used for air exhaust, or 3 internal flow channels can be used for air exhaust, or 2 internal flow channels can be used for air exhaust, or 3 internal flow channels can be used for air exhaust, or 1 internal flow channel interface can be used for 4 external flow channel interfaces according to actual needs.

The outer flow channel connection 11 is used internally for connecting the inner flow channel connections 21, and any outer flow channel connection 11 can be connected with any inner flow channel connection 21. The internal flow passage interface 21 may be used for discharging fluid and also for sucking fluid. In other embodiments, the number of the outer fluid passage ports 11 and the inner fluid passage ports 21 may be different from that of the present embodiment.

Further, the fluid control assembly 2 further comprises a driving mechanism, the injector 22 comprises a fluid container 221 and a piston push rod 222, control input ends of the piston push rod 222 and the flow passage switching valve 23 are connected with an output end of the driving mechanism, and the driving mechanism is connected with a control output end of the controller 3. In other embodiments, a person skilled in the art may select another configuration of syringe 22 as desired for the experiment.

The driving mechanism is controlled by the controller 3, and the syringe 22 can discharge the fluid in the fluid container 221 and suck the fluid into the fluid container 221 under the action of the driving mechanism. The controller 3 can control the movement speed of the piston push rod 222 to be faster or slower through the driving mechanism, so that the fluid flow is increased or decreased.

Further, the driving mechanism includes a flow channel switching servo motor 241, a linear module 242, a planetary reducer 243 and a linear module servo motor 244; the flow channel switching servo motor 241 is connected with the flow channel switching valve 23 and is used for driving the flow channel switching valve 23 to switch the flow channel; the piston push rod 222 is connected with a linear module servo motor 244 through a linear module 242 and a planetary reducer 243 in sequence.

The linear module servo motor 244 controls the linear module 242 to move back and forth according to the control signal provided by the controller 3, so as to push the piston head of the piston rod 222 to move in the fluid container 221, and thus positive pressure can be generated to discharge fluid or negative pressure can be generated to suck fluid. Because the servo motor is used together with an actuating mechanism of a planetary reducer, the piston push rod 222 can start or stop moving at any time, the moving speed can be very low, the moving precision can be very high, the flow of fluid can be well controlled, and the fluid control precision can be upgraded by being matched with the fluid container 221 with a small inner diameter and the piston head with a small diameter.

Further, a touch screen assembly 12 is arranged on the housing 1, and an output end of the touch screen assembly 12 is connected with the controller 3. The operator provides commands to the controller 3 via the touch screen assembly 12, causing the controller 3 to control the action of the fluid control assembly 2 according to the set steps and parameters to control the flow and direction of the fluid and to time the fluid back and forth in the pipe.

Further, the inner fluid passage port 21 is connected to the outer fluid passage port 11 via a teflon pipe (not shown). In other embodiments, one skilled in the art can select pipes of other materials as needed for experiments.

Further, the fluid container 221 is a cylindrical glass tube. In other embodiments, one skilled in the art may select other materials and/or shapes for the fluid container 221 according to the experimental needs.

Further, the top surface of the housing 1 is provided with a fixing portion 13, and the fixing portion 13 is used for connecting a cantilever. In other embodiments, the fixing portion 13 may not be provided.

Further, the bottom surface of the housing 1 is provided with a handle 14, which is convenient for an operator to move the nanofluidic device in all directions. In other embodiments, the handle 14 may not be provided.

Further, the external flow channel interface 11 is arranged on the outer side surface of the shell 1, so that the use is more convenient, and the pipeline for connecting the experimental fluid (or the fluid rod) is shorter. In other embodiments, the internal flow channel port 21 may be directly connected to the experimental fluid (or fluid rod) by a pipe, the external flow channel port 11 may be disposed at the top of the housing 1, the external flow channel port 11 may be connected to the experimental fluid (or fluid rod) by a pipe, the top surface of the housing 1 is provided with the offset hole 15, and the pipe passes through the offset hole 15.

A switching power supply 4 and a fan 5 are further arranged in the housing 1 and are respectively used for supplying power to the nanofluidic device and dissipating heat.

The working process is as follows:

among the 6 external

flow passage ports

11, 1 is connected with a waste container, 1 is connected with a fluid rod, and 4 are respectively connected with 4 different experimental fluids; the 6 external flow connections 11 are each connected to 6 internal flow connections 21. The operator sets the fluid flow direction and flow parameters by selecting the external flow channel interface 11 corresponding to the desired fluid material through the touch screen assembly 12.

According to the parameters set by the operator, the controller 3 sends control signals to the fluid control assembly 2, causing the fluid control assembly 2 to perform the corresponding actions: controlling the flow channel switching valve 23 to switch the flow channel, so that the corresponding internal flow channel interface 21 is in butt joint with the injector 22; the syringe 22 is controlled to discharge or draw fluid into the container of the syringe 22 depending on the set flow direction.

Further, before starting the experiment, or after completing the experiment, the fluid control assembly 2 interfaces the internal flow passage interface 21 connected to the waste container with the syringe 22, and controls the syringe 22 to drain the fluid in the container of the syringe 22.

The foregoing is only a preferred embodiment of the present invention, and is not intended to limit the scope of the invention. It should be understood that any modification, equivalent replacement, or improvement made by those skilled in the art after reading the present specification shall fall within the scope of the present invention.

Claims

1. A nanofluidic device, comprising: the device comprises a shell, wherein a fluid control assembly and a controller are arranged in the shell, and the output end of the controller is connected with the control input end of the fluid control assembly; the fluid control assembly is provided with a flow passage switching valve, an injector and a plurality of internal flow passage interfaces, and the flow passage switching valve is used for switching the internal flow passage interfaces communicated with the injector; the shell is provided with a plurality of external flow passage interfaces, and different internal flow passage interfaces are respectively connected with different external flow passage interfaces.

2. The nanofluidic device of claim 1, wherein: the fluid control assembly further comprises a driving mechanism, the injector comprises a fluid container and a piston push rod, the control input ends of the piston push rod and the flow channel switching valve are connected with the output end of the driving mechanism, and the driving mechanism is connected with the control output end of the controller.

3. The nanofluidic device of claim 2, wherein: the driving mechanism comprises a runner switching servo motor, a linear module, a planetary reducer and a linear module servo motor; the runner switching servo motor is connected with the runner switching valve and used for driving the runner switching valve to switch runners; the piston push rod is connected with the linear module servo motor through the linear module and the planetary reducer in sequence.

4. The nanofluidic device of claim 2, wherein: the fluid container is a cylindrical glass tube.

5. The nanofluidic device of claim 1, wherein: the shell is provided with a touch screen assembly, and the touch screen assembly is connected with the controller.

6. The nanofluidic device of claim 1, wherein: the number of the external flow passage interfaces and the number of the internal flow passage interfaces are both 6; of the 6 external flow joints, 1 was used as a waste outlet and the remaining 5 were used to connect experimental fluids or fluid rods, respectively.

7. The nanofluidic device of claim 1, wherein: the top surface outside of shell is equipped with the fixed part, and the fixed part is used for connecting the cantilever beam.

8. The nanofluidic device of claim 7, wherein: the handle is arranged on the outer side of the bottom surface of the shell.

9. The nanofluidic device of claim 1, wherein: the external flow passage interface is arranged on the outer side surface of the shell.

10. The nanofluidic device of claim 1, wherein: the inner runner joint is connected with the outer runner joint through a polytetrafluoroethylene pipeline.