CN214201962U - Structure of hard oxygen permeable contact lens - Google Patents

Abstract

The utility model provides a hard oxygen permeation contact lens structure, the composition of this lens is for including the hexafluoroisopropyl methacrylate of predetermineeing weight ratio constitution, 3- (methacryloyloxy) propyl tris (trimethylsiloxane) silane, neopentyl glycol dimethacrylate, methacrylic acid, the cross-linking agent, 2, 5-dimethyl-2, 5-two (2-ethylhexanoic acid peroxide) hexane and 2,2 ' -dihydroxy-4, 4 ' -dimethoxy benzophenone, the polymer condensate that can form through the polymerization of these plural number monomers can have good oxygen permeation, and also have higher hardness and mechanical strength, so that can promote user's comfort level when wearing hard oxygen permeation contact lens, and reduce the corneal pathological change.

Description

Structure of hard oxygen permeable contact lens

Technical Field

The utility model relates to a hard oxygen permeation contact lens structure, in particular to a lens formed by polymerizing a plurality of monomers, which has excellent oxygen permeation and higher hardness and mechanical strength, so that the comfort of a user can be improved when wearing the hard oxygen permeation contact lens, and the pathological changes of the cornea can be reduced.

Background

Along with research, development and innovation of various electronic and electrical products, people are convenient and fast in daily life and work, and especially, the popularization of application of electronic products in communication and internet is caused, so that many people are immersed in the use field of electronic products, the coverage range of the electronic products is quite wide for a long time, no matter office workers, student groups, middle-aged and old people and the like, the phenomenon of low head is derived, the conditions of eye vision loss, injury and the like of many people are serious day by day, and the shortsightedness population is relatively improved.

Furthermore, people can have myopia due to the fact that the light bending ability of the eyes is not matched with the length of the eyes, the eye axis is overlong or the arc of the cornea is too steep, so that an imaging point of a visual object falls in front of the retina, and the visual object is blurred during imaging, therefore, the light bending ability of the eyes needs to be reduced for correcting the myopia, and the light bending ability of the cornea accounts for about 80% of the whole eyes, so that the myopia correcting effect can be achieved by only reducing the refractive power of the cornea.

At present, there are several methods for correcting ametropia, such as wearing a spectacle, wearing a contact lens, performing corneal myopia surgery or wearing a corneal plastic-molded plate, however, the common contact lenses include both soft type and hard type, the material of the hard oxygen permeable contact lens in the past is polymethyl methacrylate (PMMA), which has good optical properties, such as high transparency, low price and easy processing, but the polymethyl methacrylate, although having good oxygen permeability, is quite hydrophobic, and is liable to generate deposits on the lens surface, thereby affecting comfort and safety of the wearer.

Therefore, in order to improve the problem of hydrophobicity, the raw material for manufacturing contact lenses has been developed to use 2-Hydroxyethylmethacrylate (HEMA) which contains an-OH functional group in its structure, and the-OH functional group can generate hydrogen bond with water, so that the problem of hydrophobicity can be improved, and the Hydroxyethyl Methacrylate has the advantage of high oxygen permeability coefficient (DK value) to improve wearing comfort, however, the mechanical strength is increasingly poor although the oxygen permeability coefficient is higher, most obviously, the disadvantage of low hardness, as shown in fig. 5, the hardness of the Hydroxyethyl Methacrylate is as high as 70duro, and the material with low hardness is not suitable for manufacturing hard contact lenses.

Therefore, how to try to solve the above-mentioned existing drawbacks and inconveniences is a direction that those skilled in the art are eagerly looking to research and improve.

SUMMERY OF THE UTILITY MODEL

Therefore, in view of the above-mentioned shortcomings, the present inventors have collected relevant information, evaluated and considered in many ways, and tried and modified continuously with years of experience accumulated in the industry, and designed a new patent for the polymer material structure of the hard oxygen permeable contact lens.

In order to achieve the above object, the utility model adopts the following technical scheme:

a hard oxygen permeable contact lens structure characterized by: one side of the lens is formed with an inner surface attached to the corneal surface of the eyeball, the other side of the lens is formed with an outer surface contacted with the eyelid, the lens is made of hexafluoroisopropyl methacrylate, two sides of the inner surface of the lens are provided with inclined plane sections which incline outwards, and the two inclined plane sections are respectively provided with an arc section which extends to the outer surface outwards.

The hard oxygen permeable contact lens structure wherein: the cross-linking agent is polydimethylsiloxane methacrylate or polydimethylsiloxane methyl crotonate.

The utility model has the main advantages that the polymer condensate formed by polymerizing the plurality of monomers has excellent oxygen permeability and higher hardness and mechanical strength, so that the comfort level of a user can be improved when the user wears the hard oxygen permeable contact lens, and the purpose of reducing the pathological changes of the cornea is achieved.

Another advantage of the present invention is that the plurality of monomers of the lens include poly (ethylene glycol) methacrylate, N-vinyl pyrrolidone, or acrylamide, thereby increasing the overall hydrophilicity.

Drawings

Figure 1 is a side view of the lens of the present invention.

Fig. 2 is a flow chart of the present invention.

FIG. 3 is a graph showing the oxygen permeability test of the present invention.

Fig. 4 is a hardness test chart of the present invention.

Fig. 5 is a hardness test chart of the conventional HEMA.

Description of reference numerals: 1-a lens; 11-an inner surface; 12-an outer surface; 111-a ramp section; 112-circular arc segment.

Detailed Description

To achieve the above objects and advantages, the preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings.

Referring to fig. 1, which is a side view of the lens of the present invention, it can be clearly seen from the figure that the lens 1 is a hard contact lens (e.g. a plastic cornea lens or a scleral lens) which can be worn on an eyeball, and is made of a material with high oxygen permeability, one side of the lens 1 is formed with an inner surface 11 which is attached to the corneal surface of the eyeball, and the other side of the lens 1 is formed with an outer surface 12 which is contacted with the eyelid, and the lens 1 is made of a fluoropolymer material which is a conventional material, and comprises: hexafluoroisopropyl methacrylate, 3- (methacryloxy) propyltris (trimethylsiloxane) silane, neopentyl glycol dimethacrylate, methacrylic acid, polydimethylsiloxane methacrylate, 2, 5-dimethyl-2, 5-bis (2-ethylhexanoic acid peroxy) hexane, 2 '-dihydroxy-4, 4' -dimethoxybenzophenone, poly (ethylene glycol) methacrylate, N-vinylpyrrolidone and acrylamide, the inner surface 11 of the lens 1 has inclined sections 111 inclined outward on both sides, and the two inclined sections 111 are connected with circular arc sections 112 extending to the outer surface 12.

The weight proportion of the hexafluoroisopropyl methacrylate is between 1 and 50 percent, the weight proportion of the 3- (methacryloyloxy) propyl tris (trimethylsiloxane) silane is between 1 and 40 percent, the weight proportion of the neopentyl glycol dimethacrylate is between 1 and 15 percent, the weight proportion of the methacrylic acid is between 1 and 20 percent, the weight proportion of the polydimethylsiloxane methacrylate is between 1 and 10 percent, the weight proportion of the 2, 5-dimethyl-2, 5-bis (2-ethylhexanoic acid peroxide) hexane is between 0.1 and 1 percent, the weight proportion of the 2,2 '-dihydroxy-4, 4' -dimethoxybenzophenone is between 0.1 and 1 percent, the weight proportion of the poly (ethylene glycol) methacrylate is between 0.1 and 1 percent, the weight proportion of the N-vinyl pyrrolidone is 0.1-1%, and the weight proportion of the acrylamide is 0.1-1%.

Preferably, the weight proportion of hexafluoroisopropyl methacrylate is 40%, the weight proportion of 3- (methacryloyloxy) propyl tris (trimethylsiloxane) silane is 25%, the weight proportion of neopentyl glycol dimethacrylate is 9%, the weight proportion of methacrylic acid is 15%, the weight proportion of polydimethylsiloxane methacrylate is 8%, the weight proportion of 2, 5-dimethyl-2, 5-bis (2-ethylhexanoic acid peroxy) hexane is 1%, the weight proportion of 2,2 '-dihydroxy-4, 4' -dimethoxybenzophenone is 0.5%, the weight proportion of poly (ethylene glycol) methacrylate is 0.5%, the weight proportion of N-vinylpyrrolidone is 0.5%, and the weight proportion of acrylamide is 0.5%.

Referring to fig. 2, fig. 3 and fig. 4, the flow chart, the oxygen permeability test chart and the hardness test chart of the present invention are shown, as can be clearly seen from the drawings, the manufacturing method of the lens 1 raw material of the present invention comprises the following steps:

(A) a plurality of monomers comprising hexafluoroisopropyl methacrylate, 3- (methacryloyloxy) propyl tris (trimethylsiloxane) silane, neopentyl glycol dimethacrylate, methacrylic acid, a cross-linking agent, 2, 5-dimethyl-2, 5-bis (2-ethylhexanoate peroxy) hexane, and 2,2 '-dihydroxy-4, 4' -dimethoxybenzophenone in a predetermined weight ratio can be added into a container (such as a beaker or a batch heating stirrer) to contain a solution containing the plurality of monomers, and the solution is heated to a predetermined temperature by a heating device to cause the plurality of monomers contained in the solution to undergo a polymerization reaction and to be cured to form a polymer cured product.

(B) Pouring the solution in the container into a vessel (such as a rod-shaped mold), and placing the vessel in an oven to perform thermosetting operation for a preset time at a preset temperature so as to purify a plurality of monomers contained in the solution, thereby forming a high polymer cured product without monomers inside.

(C) Then the polymer condensate without monomer inside is placed in an annealing device (such as an annealing furnace) to anneal the polymer condensate without monomer inside, and the polymer condensate after annealing treatment can become the raw material of the lens 1, thus completing the manufacturing operation of the utility model.

The container in the step (a) may be filled with a solvent, and the solvent may be ethylene dioxide (anhydrous dioxane).

The cross-linking agent in the step (A) may be polydimethylsiloxane methacrylate or polydimethylsiloxane methyl crotonate.

In addition, the plural monomers in the container in the step (A) can be further added with poly (ethylene glycol) methacrylate, N-vinyl pyrrolidone or acrylamide, and the material of the lens 1 is added with poly (ethylene glycol) methacrylate, N-vinyl pyrrolidone or acrylamide, so that the whole hydrophilicity can be improved.

Furthermore, the heating device in the step (a) may be a heating plate, an alcohol lamp or other devices capable of providing heat energy, and the preset temperature heated by the heating device may be 100 ℃, and during the heating process by the heating device, the stirring device may be further used for stirring.

And if the container in the step (A) is a batch heating stirrer, the container can be matched with a peristaltic pump for use, so that the solution in the container can be poured into a vessel through the peristaltic pump.

However, when the vessel in the step (B) is placed in an oven for thermal curing, the vessel is placed in an oven at 65 ℃ for at least 68 hours for thermal curing, and then heated to a temperature greater than 100 ℃ to re-cure the monomers in the vessel, and then heated to 220 ℃ to break the bonds between the silicon and fluorine bonds, thereby rearranging the molecules of the solution to generate a purification reaction, and further forming a polymer cured product.

In addition, step (B) is carried out before adding reversible addition-fragmentation polymerization (RAFT) reagent to make the polymerization reaction reversible addition-fragmentation chain transfer polymerization, the reversible addition fragmentation chain transfer polymerization reaction can polymerize the-OH group containing hydrophilic units and the monomer containing long carbon chains, and the polymerization speed can be slower through the reversible addition fragmentation chain transfer polymerization reaction, further, various monomers in the solution are effectively contacted, so that a high molecular polymer with high molecular weight, high dispersibility and stability is formed, thus, the hydrophilicity of the material can be improved, and the reversible polyaddition fragmentation chain transfer polymerization reagent can be dithiobenzoate (Dithiobenzoates), Trithiocarbonates (Trithiocarbonates), Dithiocarbamates (Dithiocarbamates), Xanthates (Xanthates) or the like.

The purification reaction in step (B) is preferably a reversible addition fragmentation chain transfer polymerization, but in practice, it may be a polymerization reaction such as a free radical polymerization (free radial polymerization), an ionic polymerization (ionic polymerization), a condensation polymerization (condensation polymerization), a stepwise addition polymerization (stepwise addition polymerization) or an addition condensation polymerization (addition polymerization).

After the polymerization reaction in the step (B) is performed, the polymer cured product can be irradiated with gamma rays to ensure that the unpolymerized plural monomers are polymerized again, thereby increasing the polymerization rate.

The oxygen permeability (DK value) of the lens 1 raw material in the step (C) is between 170-200 barrers, and the hardness is between 76-81 duro, and refer to fig. 3 and 4, which are the oxygen permeability test chart and the hardness test chart of the present invention, as can be clearly seen from the chart, the average value after the oxygen permeability test of the lens 1 raw material is 189 barrers, and the average value after the hardness test of the lens 1 raw material is 77 duro.

The utility model discloses a can add the container with a plurality of kinds of monomers earlier, and heat to predetermineeing the temperature through heating device, so that a plurality of kinds of monomers produce polymerization, and then the solidification forms the polymer cured object, at this moment, solution in the container is for being thick form, and pour the solution into the household utensils in, place the household utensils in the oven thermosetting operation again, so that a plurality of monomers in the solution produce purification reaction, and then rearrange and form inside no free polymer cured object, place the polymer cured object in annealing device again, in order to carry out annealing treatment to the polymer cured object, and via the polymer cured object after annealing treatment alright become the raw materials of lens 1, it is because of a plurality of kinds of monomers for including methacrylic acid hexafluoroisopropyl ester that predetermine the weight ratio and constitute, 3- (methacryloyloxy) propyl tri (trimethylsiloxane) silane, neopentyl glycol dimethacrylate, Methacrylic acid, a cross-linking agent, 2, 5-dimethyl-2, 5-bis (2-ethylhexanoic acid per-oxidation) hexane and 2,2 '-dihydroxy-4, 4' -dimethoxybenzophenone, so that a polymer cured product obtained by polymerizing the plurality of monomers has excellent oxygen permeability and higher hardness and mechanical strength, so that the comfort of a user can be improved when wearing the lens 1, and the corneal lesion can be reduced.

The lens 1 can be manufactured by multi-section heating in the steps (A) and (B), and the heating temperature in the step (B) is higher than that in the step (A), so that the condition that the surface structure of the lens 1 is damaged due to one-time high-temperature heating can be avoided by utilizing the multi-section heating, and the product yield can be further improved.

The foregoing description is intended to be illustrative rather than limiting, and it will be appreciated by those skilled in the art that many modifications, variations or equivalents may be made without departing from the spirit and scope of the invention as defined in the appended claims.

Claims (2)

1. A hard oxygen permeable contact lens structure characterized by: one side of the lens is formed with an inner surface attached to the corneal surface of the eyeball, the other side of the lens is formed with an outer surface contacted with the eyelid, the lens is made of hexafluoroisopropyl methacrylate, two sides of the inner surface of the lens are provided with inclined plane sections which incline outwards, and the two inclined plane sections are respectively provided with an arc section which extends to the outer surface outwards.

2. The hard oxygen permeable contact lens structure of claim 1, wherein: the cross-linking agent is polydimethylsiloxane methacrylate or polydimethylsiloxane methyl crotonate.

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