CN214142291U - Be used for capillary encapsulating device - Google Patents

Be used for capillary encapsulating device Download PDF

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Publication number
CN214142291U
CN214142291U CN202022659667.6U CN202022659667U CN214142291U CN 214142291 U CN214142291 U CN 214142291U CN 202022659667 U CN202022659667 U CN 202022659667U CN 214142291 U CN214142291 U CN 214142291U
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piston
capillary
assembly
communicated
screw rod
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CN202022659667.6U
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Chinese (zh)
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唐德军
黄积朋
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Nanjing Superyears Gene Technology Co ltd
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Nanjing Superyears Gene Technology Co ltd
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Abstract

The utility model discloses a be used for capillary encapsulating device inject the polymer separation in the storage bottle and glue, and in the time of lead screw subassembly return, through the pipe with the check valve, the polymer separation is glued and is inhaled push the piston in the piston chamber, work as the lead screw motor is in when the drive of encoder moves down, drive the piston post extrusion the piston chamber is pressed simultaneously the push rod is opened the gas switch subassembly makes gas drive in the jam bottle the gleitbretter blocks up the branch pipe, then closes the block switch, the polymer separation in the piston chamber is glued and can be under the high pressure, through the capillary passageway, stable, reliable entering capillary.

Description

Be used for capillary encapsulating device
Technical Field
The utility model relates to the technical field of medical equipment, especially, relate to a be used for capillary encapsulating device.
Background
The capillary channel is an electrophoresis channel for data acquisition of a first-generation sequencer, and how to safely and uniformly fill polymer separation gel into the capillary channel is the key for ensuring the stability and reliability of a sequencing result. The conventional method is to press the polymer separation glue into the capillary directly at the bundling end by extrusion. The pipeline is burst due to the over-high pressure, and the capillary tube bundling end is pushed and deformed; the too low pressure causes the polymer separation gel not to be injected in a short time due to the too small inner diameter of the capillary, and the polymer separation gel cannot be stably injected into the capillary.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a be used for capillary encapsulating device, stable pours into the polymer separation to the capillary into and glues.
In order to achieve the above object, the present invention provides a capillary tube potting device, which comprises a screw rod assembly, a pushing piston, a feeding assembly and a blocking switch, wherein the pushing piston is slidably connected with the screw rod assembly and is located on one side of the screw rod assembly, the pushing piston is provided with a piston cavity, a capillary channel and a branch pipe, the piston cavity penetrates through the pushing piston, the capillary channel is communicated with the piston cavity, the branch pipe is communicated with the capillary channel, the feeding assembly is communicated with the pushing piston and is located on one side away from the screw rod assembly, and the blocking switch is communicated with the branch pipe and is located on one side of the feeding assembly;
the feeding assembly comprises a storage bottle, a guide pipe and a one-way valve, the one-way valve is communicated with the pushing piston and is positioned far away from one side of the screw rod assembly, the guide pipe is communicated with the one-way valve and is positioned far away from one side of the pushing piston, and the storage bottle is communicated with the guide pipe and is positioned far away from one side of the one-way valve.
The screw rod assembly comprises a screw rod motor and a piston column, the piston column is connected with the pushing piston in a sliding mode and is located in the piston cavity, and the screw rod motor is fixedly connected with the piston column and is located on one side far away from the pushing piston.
The screw rod assembly further comprises an encoder, and the encoder is connected with the screw rod motor and located on one side far away from the piston column.
The blocking switch comprises a connecting pipe and a switch mechanism, the connecting pipe is communicated with the branch pipe and is positioned on one side of the branch pipe, and the switch mechanism is communicated with the connecting pipe and is positioned on one side far away from the pushing piston.
Wherein, on-off mechanism is including blockking up bottle, push rod, gas switch subassembly and gleitbretter, the gas switch subassembly with the connecting pipe intercommunication, and be located keep away from connecting pipe one side, the gleitbretter with the gas switch subassembly with connecting pipe sliding connection, and be located in the gas switch subassembly, the push rod with gas switch subassembly sliding connection, and be located in the gas switch subassembly, block up the bottle with the gas switch subassembly can dismantle the connection to be located around the gas switch subassembly.
The gas switch assembly comprises a fixing plate, a plurality of baffles and a conical tube, the fixing plate is in sliding connection with the blocking bottle and is located in the blocking bottle, the conical tube is communicated with the connecting tube and is located between the fixing plate and the connecting tube, and the baffles are rotationally connected with the fixing plate and are located between the fixing plate and the blocking bottle.
The utility model discloses a be used for capillary encapsulating device inject the polymer separation glue in the storage bottle, and in the time of lead screw subassembly return, through the pipe with the check valve, the polymer separation glue is inhaled push the piston in the piston chamber, work as the lead screw motor is in when the drive of encoder moves down, drive the piston post extrusion the piston chamber is pressed simultaneously the push rod is opened the gas switch subassembly makes gas drive in the jam bottle the gleitbretter blocks up the branch pipe, then closes the block switch, the polymer separation glue in the piston chamber can pass through capillary passageway, stable, reliable entering capillary.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a capillary glue pouring device provided by the present invention.
Fig. 2 is a cross-sectional view of the pushing piston provided by the present invention.
Fig. 3 is a schematic structural diagram of the blocking switch provided by the present invention.
1-screw rod component, 2-pushing piston, 3-feeding component, 4-blocking switch, 5-piston cavity, 6-capillary channel, 7-branch pipe, 8-storage bottle, 9-conduit, 10-one-way valve, 11-screw rod motor, 12-piston column, 13-encoder, 14-connecting pipe, 15-switching mechanism, 16-blocking bottle, 17-push rod, 18-gas switch component, 19-sliding sheet, 20-fixing plate, 21-baffle plate and 22-conical pipe.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary and intended to be used for explaining the present invention, and should not be construed as limiting the present invention.
In the description of the present invention, it is to be understood that the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on those shown in the drawings, and are merely for convenience of description and simplicity of description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention. In addition, in the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.
Referring to fig. 1 to 3, the present invention provides a capillary potting device, which includes a screw assembly 1, a pushing piston 2, a feeding assembly 3 and a blocking switch 4, wherein the pushing piston 2 is slidably connected to the screw assembly 1 and located at one side of the screw assembly 1, the pushing piston 2 has a piston cavity 5, a capillary passage 6 and a branch pipe 7, the piston cavity 5 penetrates through the pushing piston 2, the capillary passage 6 is communicated with the piston cavity 5, the branch pipe 7 is communicated with the capillary passage 6, the feeding assembly 3 is communicated with the pushing piston 2 and located at one side away from the screw assembly 1, and the blocking switch 4 is communicated with the branch pipe 7 and located at one side of the feeding assembly 3;
the feeding assembly 3 comprises a storage bottle 8, a conduit 9 and a one-way valve 10, the one-way valve 10 is communicated with the pushing piston 2 and is positioned far away from one side of the screw rod assembly 1, the conduit 9 is communicated with the one-way valve 10 and is positioned far away from one side of the pushing piston 2, the storage bottle 8 is communicated with the conduit 9 and is positioned far away from one side of the one-way valve 10.
In this embodiment, a polymer separation gel is injected into the storage bottle 8, and is sucked into the piston chamber 5 of the pushing piston 2 through the conduit 9 and the one-way valve 10 while the screw assembly 1 is returned, and when the screw assembly 1 is operated downwards, the piston chamber 5 is pressed, and the blocking switch 4 is actuated to block the branch pipe 7, so that the polymer separation gel in the piston chamber 5 can stably and reliably enter the capillary through the capillary passage 6 under high pressure.
After glue filling is finished, the blocking switch 4 can be opened again, the branch pipe 7 is opened, and cleaning liquid in the blocking switch 4 enters the piston cavity 5 to clean the piston cavity 5 and the capillary channel 6 by means of returning of the screw rod assembly 1.
Further, the screw rod assembly 1 comprises a screw rod motor 11 and a piston column 12, the piston column 12 is slidably connected with the pushing piston 2 and is located in the piston cavity 5, and the screw rod motor 11 is fixedly connected with the piston column 12 and is located at one side far away from the pushing piston 2.
In this embodiment, in order to make the polymer separation gel stably and reliably enter the capillary, the stable driving of the screw motor 11 drives the piston column 12 to stably extrude the piston cavity 5, so that the air pressure in the piston cavity 5 gradually rises, and the polymer separation gel stably and reliably enters the capillary.
Further, the screw rod assembly 1 further comprises an encoder 13, and the encoder 13 is connected with the screw rod motor 11 and is located on one side far away from the piston column 12.
In this embodiment, when the lead screw motor 11 performs a downward stepping motion, the magnitude of the torque is limited by the motor current, and when the torque requirement is higher than the motor current power, the lead screw motor 11 cannot move downward.
The relationship between the line pressure limit (P) and the motor current (a) is:
p is a constant coefficient of the asynchronous motor, K is K/S, and S is the displacement area of the displacement piston 2.
The control of the screw motor 11 is matched with the encoder 13, and whether the pipeline pressure exceeds a set value or not can be easily judged under the FPGA control program. The specific method comprises the following steps:
a. 5/200 circles of continuous step motor advance
b. The line encoder 13 is read 200 steps.
c. The number of the advancing steps is less than 5, which means that the resistance of the screw motor 11 is too large to exceed the set pressure limit value.
d. And stopping propelling the stepping motor after the pressure exceeds the limit, and continuing propelling after waiting for a set value.
e. And repeating the steps a, b, c and d until the vehicle correctly moves to the appointed position.
Further, the blocking switch 4 comprises a connecting pipe 14 and a switch mechanism 15, the connecting pipe 14 is communicated with the branch pipe 7 and is positioned on one side of the branch pipe 7, and the switch mechanism 15 is communicated with the connecting pipe 14 and is positioned on one side far away from the pushing piston 2.
In this embodiment, when the branch pipe 7 needs to be blocked, the opening and closing mechanism 15 is started to operate the opening and closing mechanism 15, the joint between the connecting pipe 14 and the pushing piston 2 is sealed and blocked, and when the sealing is not needed, the opening and closing mechanism 15 is started again to open the branch pipe, and the pushing piston 2 is cleaned.
Further, the switch mechanism 15 includes a blocking bottle 16, a push rod 17, a gas switch assembly 18 and a sliding piece 19, the gas switch assembly 18 is communicated with the connecting pipe 14 and is located far away from one side of the connecting pipe 14, the sliding piece 19 is slidably connected with the gas switch assembly 18 and the connecting pipe 14 and is located in the gas switch assembly 18, the push rod 17 is slidably connected with the gas switch assembly 18 and is located in the gas switch assembly 18, and the blocking bottle 16 is detachably connected with the gas switch assembly 18 and is located around the gas switch assembly 18.
In the embodiment, the blocking bottle 16 has a double-layer liner structure, the innermost layer is filled with high-pressure gas, the middle layer is cleaning liquid, when a branch needs to be blocked, the push rod 17 is pressed, the gas switch component 18 is opened, the high-pressure gas in the blocking bottle 16 drives the sliding piece 19 to slide in the connecting pipe 14 until the branch pipe 7 is sealed and blocked, and the gas switch component 18 is closed to keep the pressure of the high-pressure gas on the sliding piece 19 constant; when not needing to seal, press again push rod 17 opens gas switch subassembly 18, high-pressure gas fall back extremely in blockking up the bottle 16, when needs clean, order about piston post 12 upward movement, close check valve 10, then press push rod 17 makes gas switch subassembly 18 for it produces the displacement to block up bottle 16, make connecting pipe 14 with gas switch subassembly 18 disconnection, at this moment, the clean liquid in blockking up the bottle 16 is along with connecting pipe 14 gets into piston chamber 5 cleans, and the discharge of clean liquid after the cleanness is accomplished is unanimous with the operation that the capillary was filled to the polymer separation glue, and easy operation is convenient for clean the device, guarantees the effect of encapsulating.
Further, the gas switching assembly 18 includes a fixing plate 20, a plurality of baffles 21 and a tapered tube 22, wherein the fixing plate 20 is slidably connected to the stopper bottle 16 and is located in the stopper bottle 16, the tapered tube 22 is communicated with the connecting tube 14 and is located between the fixing plate 20 and the connecting tube 14, and the plurality of baffles 21 are rotatably connected to the fixing plate 20 and are located between the fixing plate 20 and the stopper bottle 16.
In the present embodiment, the tapered tube 22 is used to connect with the connection tube 14, and the tapered tube 22 is provided to facilitate sealing the connection tube 14 when the sliding piece 19 is returned, so as to avoid leakage of high-pressure gas, and to avoid liquid entering the high-pressure gas through the tapered tube 22 when the cleaning liquid is discharged; when the push rod 17 is pressed, the 4 pillars of the push rod 17 are used to open the baffle 21 around the fixed plate 20, and then the discharge and collection of high-pressure gas are realized.
The utility model discloses a be used for capillary encapsulating device inject the polymer separation glue in the storage bottle 8, and in the time of 1 return of lead screw subassembly, through pipe 9 with check valve 10, the polymer separation glue is inhaled push piston 2 in the piston chamber 5, work as lead screw motor 11 is in when the drive of encoder 13 moves down, drive piston post 12 extrudees piston chamber 5 presses simultaneously push rod 17 opens gas switch subassembly 18 makes the gaseous drive in the jam bottle 16 gleitbretter 19 blocks up branch pipe 7, then closes block up switch 4, the polymer separation glue in the piston chamber 5 can be under the high pressure, through capillary passageway 6, stable, reliable entering capillary.
While the invention has been described with reference to a preferred embodiment, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention.

Claims (6)

1. A glue pouring device for capillary tubes is characterized in that,
the capillary glue pouring device comprises a screw rod assembly, a pushing piston, a feeding assembly and a blocking switch, wherein the pushing piston is connected with the screw rod assembly in a sliding mode and is located on one side of the screw rod assembly, the pushing piston is provided with a piston cavity, a capillary channel and a branch pipe, the piston cavity penetrates through the pushing piston, the capillary channel is communicated with the piston cavity, the branch pipe is communicated with the capillary channel, the feeding assembly is communicated with the pushing piston and is located on one side away from the screw rod assembly, and the blocking switch is communicated with the branch pipe and is located on one side of the feeding assembly;
the feeding assembly comprises a storage bottle, a guide pipe and a one-way valve, the one-way valve is communicated with the pushing piston and is positioned far away from one side of the screw rod assembly, the guide pipe is communicated with the one-way valve and is positioned far away from one side of the pushing piston, and the storage bottle is communicated with the guide pipe and is positioned far away from one side of the one-way valve.
2. The capillary potting apparatus of claim 1,
the screw rod assembly comprises a screw rod motor and a piston column, the piston column is connected with the pushing piston in a sliding mode and is located in the piston cavity, and the screw rod motor is fixedly connected with the piston column and is located on one side away from the pushing piston.
3. The capillary potting apparatus of claim 2,
the screw rod assembly further comprises an encoder, and the encoder is connected with the screw rod motor and located on one side far away from the piston column.
4. The capillary potting apparatus of claim 1,
the blocking switch comprises a connecting pipe and a switch mechanism, the connecting pipe is communicated with the branch pipe and is positioned on one side of the branch pipe, and the switch mechanism is communicated with the connecting pipe and is positioned on one side far away from the pushing piston.
5. The capillary potting apparatus of claim 4,
the switch mechanism comprises a blocking bottle, a push rod, a gas switch assembly and a slip sheet, wherein the gas switch assembly is communicated with the connecting pipe and is located far away from one side of the connecting pipe, the slip sheet is connected with the gas switch assembly in a sliding mode and is located in the gas switch assembly, the push rod is connected with the gas switch assembly in a sliding mode and is located in the gas switch assembly, and the blocking bottle is connected with the gas switch assembly in a detachable mode and is located around the gas switch assembly.
6. The capillary potting apparatus of claim 5,
the gas switch subassembly includes fixed plate, a plurality of baffle and conical duct, the fixed plate with block up bottle sliding connection, and be located in blocking up the bottle, the conical duct with the connecting pipe intercommunication, and be located the fixed plate with between the connecting pipe, it is a plurality of the baffle with the fixed plate rotates to be connected, and is located the fixed plate with block up between the bottle.
CN202022659667.6U 2020-11-17 2020-11-17 Be used for capillary encapsulating device Active CN214142291U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202022659667.6U CN214142291U (en) 2020-11-17 2020-11-17 Be used for capillary encapsulating device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202022659667.6U CN214142291U (en) 2020-11-17 2020-11-17 Be used for capillary encapsulating device

Publications (1)

Publication Number Publication Date
CN214142291U true CN214142291U (en) 2021-09-07

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202022659667.6U Active CN214142291U (en) 2020-11-17 2020-11-17 Be used for capillary encapsulating device

Country Status (1)

Country Link
CN (1) CN214142291U (en)

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