CN214105992U

CN214105992U - Processing equipment is used in preparation of high-purity NAD

Info

Publication number: CN214105992U
Application number: CN202022972589.5U
Authority: CN
Inventors: 王国权; 冯波; 庄峰锋
Original assignee: Huahengjian Beijing Biotechnology Co ltd
Current assignee: Huahengjian Beijing Biotechnology Co ltd
Priority date: 2020-12-11
Filing date: 2020-12-11
Publication date: 2021-09-03
Anticipated expiration: 2030-12-11

Abstract

The utility model discloses a processing equipment is used in preparation of high-purity NAD, the power distribution box comprises a box body, the middle part of box inner wall is fixed hopper and the filter box of being equipped with respectively, the middle part of hopper is through the fixed intercommunication in middle part on first solenoid valve and filter box top, the both sides on hopper top and the both sides of box inner wall bottom fixed mounting respectively have two sets of electric rods, the top and the bottom of box inner wall are equipped with two stirring subassemblies respectively, the fixed first filter screen that is equipped with the slope in inside of filter box, one side fixed interlude of filter box is connected with row's miscellaneous pipe, fixed mounting has the second solenoid valve on the row's miscellaneous pipe, the beneficial effects of the utility model are that: can be two appearance chambeies with the internal partitioning of box through hopper and filter box cooperate, carry out the preliminary treatment to the crude solution of NAD through the top of hopper, the crude solution of NAD after rethread circulation reposition of redundant personnel subassembly will be handled is carried to the bottom of box inner wall and is reprocessed, then can accomplish the separation purification operation of the crude solution of NAD alone.

Description

Processing equipment is used in preparation of high-purity NAD

Technical Field

The utility model relates to a processing equipment, in particular to processing equipment is used in preparation of high-purity NAD belongs to the purification technical field of nucleotide coenzyme.

Background

NAD is a biological proper noun, the name of chinese: nicotinamide adenine dinucleotide, abbreviated as coenzyme I. At present, the preparation method of NAD is mainly divided into chemical synthesis method and biological catalysis method, wherein the biological catalysis method includes biological fermentation method and enzyme catalysis method, and the method is gradually the mainstream direction because it has the advantages of environmental protection and no pollution compared with the chemical synthesis method. The crude product solution (enzyme reaction solution or biological fermentation solution) obtained by preparing NAD by a biological catalysis method contains a large amount of impurities besides NAD, and the purity of NAD is only 20-40%, so that a relatively pure NAD product can be obtained by further separation and purification treatment.

At present, the NAD preparation is generally purified for multistep with the separation and purification mode, need filter repeatedly, adjust the temperature and adjust PH, and current processing equipment for NAD preparation can't accomplish the separation and purification operation alone, and the separation and purification is wasted time and energy, influences work efficiency, and can't accomplish continuous production.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a processing equipment is used in preparation of high-purity NAD to solve the problem that the separation purification operation can't be accomplished alone to the current processing equipment is used in NAD preparation that proposes in the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme: the processing equipment for preparing the high-purity NAD comprises a box body, wherein the middle part of the inner wall of the box body is respectively and fixedly provided with a hopper and a filter box, the middle part of the hopper is fixedly communicated with the middle part of the top end of the filter box through a first electromagnetic valve, two groups of electric heating rods are respectively and fixedly arranged on two sides of the top end of the hopper and two sides of the bottom end of the inner wall of the box body, the top and the bottom of the inner wall of the box body are respectively provided with two stirring components, an inclined first filter screen is fixedly arranged in the filter box, one side of the filter box is fixedly connected with a trash discharging pipe in an inserting way, a second electromagnetic valve is fixedly arranged on the trash discharging pipe, the other side of the box body is provided with a circulating flow-dividing assembly, the other side of the top end of the box body and the bottom of one side of the box body are fixedly connected with feed pipes in an inserting way, two sides of the bottom end of the box body are respectively fixedly and alternately connected with two discharging pipes, and a third electromagnetic valve is fixedly mounted on each discharging pipe.

As a preferred technical scheme of the utility model, two the stirring subassembly includes two motors and two pivots respectively, two the motor is fixed mounting respectively at the middle part on box top and the middle part of bottom, two the pivot is rotated respectively and is installed the top of box inner wall and the bottom of inner wall, two the one end of pivot respectively with the output shaft fixed connection of two motors, two fixed a plurality of stirring leaf that is equipped with respectively in the pivot.

As a preferred technical scheme of the utility model, circulation reposition of redundant personnel subassembly includes the circulating pump, circulating pump fixed mounting is at the middle part of box opposite side, the entrance point of circulating pump passes through the bottom mounting intercommunication of connecting pipe and filter box opposite side, the exit end fixed mounting of circulating pump has the three-way pipe, two exit ends of three-way pipe communicate with the top and the bottom of box opposite side respectively through two transfer lines, fixed mounting has electric three-way valve on the three-way pipe.

As a preferred technical scheme of the utility model, the top and the bottom of box inner wall are fixed interlude respectively and are connected with two water-cooled tubes, two the water-cooled tube all is the U type form and arranges, just two water-cooled tubes all distribute with stirring leaf is crisscross.

As an optimal technical scheme of the utility model, one side of box inner wall bottom is fixed and is equipped with the second filter screen, the position of second filter screen is corresponding with the position of arranging the material pipe wherein.

As a preferred technical proposal of the utility model, four corners of the bottom end of the box body are all fixedly provided with supporting legs, the top and the bottom of the side of the box body are respectively embedded with two transparent windows, the middle part of the side of the box body is fixedly provided with a switch panel, the surface of the switch panel is respectively provided with a first electromagnetic valve control switch, an electric heating rod control switch, a motor control switch, a second electromagnetic valve control switch, a circulating control switch, an electric three-way valve control switch and two third electromagnetic valve control switches, the first electromagnetic valve, the two groups of electric heating rods, the two motors, the second electromagnetic valve, the circulating pump, the electric three-way valve and the two third electromagnetic valves are respectively electrically connected with an external power supply through a first electromagnetic valve control switch, two electric heating rod control switches, two motor control switches, a second electromagnetic valve control switch, a circulating control switch, an electric three-way valve control switch and two third electromagnetic valve control switches.

Compared with the prior art, the beneficial effects of the utility model are that: the utility model relates to a processing equipment is used in preparation of high-purity NAD, cooperate through hopper and filter box and can be two appearance chambeies with the internal partitioning of box, top through the hopper carries out the preliminary treatment to the crude product solution of NAD, the crude product solution of NAD after the rethread circulation reposition of redundant personnel subassembly will be handled is carried to the bottom of box inner wall and is reprocessed, then can accomplish the separation purification operation of the crude product solution of NAD alone, time saving and labor saving, and accomplish continuous production's purpose, can improve the degree of consistency of mixed liquid through the stirring subassembly in the separation purification process simultaneously, cooperate through electric bar and water-cooling tube and can accurate control treatment temperature, and the treatment effect is improved.

Drawings

Fig. 1 is a schematic view of the overall structure of the present invention;

fig. 2 is a schematic sectional view of the present invention.

In the figure: 1. a box body; 2. a hopper; 3. a filter box; 4. a first solenoid valve; 5. an electric heating rod; 6. a stirring assembly; 61. a motor; 62. a rotating shaft; 63. stirring blades; 7. a first filter screen; 8. a trash removal pipe; 9. a second solenoid valve; 10. a circulating flow-splitting assembly; 101. a circulation pump; 102. a three-way pipe; 103. a transfusion tube; 104. An electric three-way valve; 11. a feed tube; 12. a discharge pipe; 13. a third electromagnetic valve; 14. a second filter screen; 15. supporting legs; 16. a transparent window; 17. a switch panel; 18. a water-cooled tube.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-2, the utility model provides a processing equipment for preparing high purity NAD, comprising a box body 1, wherein the middle part of the inner wall of the box body 1 is respectively fixedly provided with a hopper 2 and a filter box 3, the middle part of the hopper 2 is fixedly communicated with the middle part of the top end of the filter box 3 through a first electromagnetic valve 4, two groups of electric heating rods 5 are respectively and fixedly arranged on the two sides of the top end of the hopper 2 and the two sides of the bottom end of the inner wall of the box body 1, the top and the bottom of the inner wall of the box body 1 are respectively provided with two stirring components 6, the inside of the filter box 3 is fixedly provided with an inclined first filter screen 7, one side of the filter box 3 is fixedly and alternately connected with a impurity discharging pipe 8, a second electromagnetic valve 9 is fixedly arranged on the impurity discharging pipe 8, the other side of the box body 1 is provided with a circulating flow dividing component 10, the inside of the box body 1, the crude solution of NAD after will handling through circulation reposition of redundant personnel subassembly 10 is carried to the bottom of box 1 inner wall and is reprocessed again, then can accomplish the separation and purification operation of the crude solution of NAD alone, labour saving and time saving, the equal fixed interlude in the bottom of the opposite side on box 1 top and box 1 one side is connected with filling tube 11, the both sides of box 1 bottom fixed interlude respectively are connected with two and arrange material pipe 12, two are arranged equal fixed mounting on material pipe 12 and are had third solenoid valve 13.

Preferably, the two stirring assemblies 6 respectively comprise two motors 61 and two rotating shafts 62, the two motors 61 are respectively and fixedly installed at the middle part of the top end and the middle part of the bottom end of the box body 1, the two rotating shafts 62 are respectively and rotatably installed at the top part of the inner wall of the box body 1 and the bottom part of the inner wall of the box body 1, one ends of the two rotating shafts 62 are respectively and fixedly connected with output shafts of the two motors 61, a plurality of stirring blades 63 are respectively and fixedly arranged on the two rotating shafts 62, the stirring blades 63 on the rotating shafts 62 are driven by the motors 61 to rotate to stir and mix, the PH of crude liquid and the uniformity of the crude liquid mixed with the solution are convenient to adjust, the circulating flow distribution assembly 10 comprises a circulating pump 101, the circulating pump 101 is fixedly installed at the middle part of the other side of the box body 1, the inlet end of the circulating pump 101 is fixedly communicated with the bottom end of the other side An electric three-way valve 104 is fixedly installed on the three-way pipe 102, the electric three-way valve 104 is adjusted to be matched with the circulating pump 101 to perform circulating flow or flow division, namely crude liquid on the hopper 2 is subjected to circulating filtration, or the pretreated crude liquid is conveyed to the bottom of the inner wall of the box body 1 to be further separated and purified, two water-cooling pipes 18 are fixedly and penetratingly connected to the top and the bottom of the inner wall of the box body 1 respectively, the two water-cooling pipes 18 are arranged in a U shape, the two water-cooling pipes 18 are distributed with the stirring blades 63 in a staggered manner, cold water can be introduced through the water-cooling pipes 18 to perform heat exchange and temperature reduction so as to ensure the purification temperature, a second filter screen 14 is fixedly arranged on one side of the bottom end of the inner wall of the box body 1, the position of the second filter screen 14 corresponds to the position of one of the discharge pipe 12, crystals can be filtered through the second filter screen 14 and retained in the box body 1 so as to be separated and obtain crystal products, four corners of the bottom end of the box body 1 are all fixedly provided with supporting legs 15, the top and the bottom of the side of the box body 1 are respectively embedded with two transparent windows 16, the middle part of the side of the box body 1 is fixedly provided with a switch panel 17, the surface of the switch panel 17 is respectively provided with a first electromagnetic valve control switch, an electric heating rod control switch, a motor control switch, a second electromagnetic valve control switch, a circulation control switch, an electric three-way valve control switch and two third electromagnetic valve control switches, a first electromagnetic valve 4, two groups of electric heating rods 5, two motors 61, a second electromagnetic valve 9, a circulating pump 101, an electric three-way valve 104 and two third electromagnetic valves 13 are respectively and electrically connected with an external power supply through the first electromagnetic valve control switch, the two electric heating rod control switches, the two motor control switches, the second electromagnetic valve control switch, the circulation control switch, the electric, the transparent window 16 is convenient for observing the stirring condition, the switch panel 17 is convenient for controlling the whole equipment, and the operation is simple and convenient.

When the processing equipment is used specifically, the utility model relates to a high-purity NAD preparation is with processing equipment, at first add the crude solution of NAD to the top of hopper 2 through the filling tube 11 on box 1 top, then adjust the pH value and carry out the preliminary treatment to the crude solution of NAD, namely open first solenoid valve 4 and circulating pump 101 through switch panel 17, adjust electric three-way valve 104 to the transfer line 103 that is in the top and lead to the liquid simultaneously, the crude liquid at the top of hopper 2 flows into the inside of filter box 3 through first solenoid valve 4 at this moment and filters through first filter screen 7 after rethread circulating pump 101 can carry the crude liquid after preliminary treatment to the top of hopper 2 again, realize the purpose of circulating flow filtration, rethread switch panel 17 after getting rid of impurity adjusts electric three-way valve 104 to the transfer line 103 that is in the bottom and leads to the liquid, can carry the crude liquid after preliminary treatment to the top of box 1 inner wall through circulating pump 101 at this moment, then the solution to be mixed is added through the feeding pipe 11 on one side of the box body 1 for reprocessing, then the separation and purification operation of the crude NAD solution can be completed independently, time and labor are saved, and the purpose of continuous production can be achieved, meanwhile, the stirring blade 63 on the rotating shaft 62 is driven by the motor 61 of the stirring component 6 to rotate in the separation and purification process for stirring and mixing, the uniformity of the mixed solution and the accuracy of PH regulation can be improved, the treatment temperature can be accurately controlled through the matching of the two groups of electric heating rods 5 and the two water cooling pipes 18, the treatment effect is further improved, the two groups of electric heating rods 5 and the two water cooling pipes 18 can be connected with a temperature control switch for use, the purpose of automatic temperature control is achieved, the device is more practical, after the treatment is finished, the two third electromagnetic valves 13 are respectively controlled by the switch panel 17 to respectively open the two discharging pipes 12 for discharging respectively, namely, the liquid is discharged through one of the discharging pipes 12, the other discharging pipe 12 discharges the product, after the long-time use, the second electromagnetic valve 9 is opened through the switch panel 17, impurities are discharged in a concentrated mode through the impurity discharging pipe 8, and the normal use of the first filter screen 7 is ensured.

In the description of the present invention, it should be understood that the indicated orientation or positional relationship is based on the orientation or positional relationship shown in the drawings, and is only for convenience of description and simplification of description, and does not indicate or imply that the indicated device or element must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the present invention.

In the present invention, unless otherwise explicitly specified or limited, for example, it may be fixedly connected, detachably connected, or integrated; can be mechanically or electrically connected; they may be directly connected or indirectly connected through an intermediate medium, and may be connected through the inside of two elements or in an interaction relationship between two elements, unless otherwise specifically defined, and the specific meaning of the above terms in the present invention will be understood by those skilled in the art according to specific situations.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The processing equipment for preparing the high-purity NAD comprises a box body (1) and is characterized in that a hopper (2) and a filter box (3) are fixedly arranged in the middle of the inner wall of the box body (1) respectively, the middle of the hopper (2) is fixedly communicated with the middle of the top end of the filter box (3) through a first electromagnetic valve (4), two groups of electric heating rods (5) are fixedly arranged on two sides of the top end of the hopper (2) and two sides of the bottom end of the inner wall of the box body (1) respectively, two stirring assemblies (6) are arranged at the top and the bottom of the inner wall of the box body (1) respectively, an inclined first filter screen (7) is fixedly arranged in the filter box (3), one side of the filter box (3) is fixedly and alternately connected with a impurity discharging pipe (8), a second electromagnetic valve (9) is fixedly arranged on the impurity discharging pipe (8), and a circulating flow dividing assembly (10) is arranged on the other side of the box body (1), the equal fixed interlude in the opposite side on box (1) top and the bottom of box (1) one side is connected with filling tube (11), the both sides of box (1) bottom are fixed interlude respectively and are connected with two row material pipes (12), two it has third solenoid valve (13) to arrange equal fixed mounting on material pipe (12).

2. The processing equipment for high purity NAD production according to claim 1, characterized in that: two stirring subassembly (6) are including two motors (61) and two pivot (62), two respectively motor (61) fixed mounting is respectively at the middle part on box (1) top and the middle part of bottom, two pivot (62) rotate respectively and install the top at box (1) inner wall and the bottom of inner wall, two the one end of pivot (62) respectively with the output shaft fixed connection of two motors (61), two it is equipped with a plurality of stirring leaf (63) to fix respectively in pivot (62).

3. The processing equipment for high purity NAD production according to claim 2, characterized in that: circulation reposition of redundant personnel subassembly (10) is including circulating pump (101), circulating pump (101) fixed mounting is in the middle part of box (1) opposite side, the inlet end of circulating pump (101) passes through the bottom mounting intercommunication of connecting pipe with filter box (3) opposite side, the exit end fixed mounting of circulating pump (101) has three-way pipe (102), two exit ends of three-way pipe (102) communicate with the top and the bottom of box (1) opposite side respectively through two transfer lines (103), fixed mounting has electronic three-way valve (104) on three-way pipe (102).

4. The processing equipment for high purity NAD production according to claim 2, characterized in that: the top and the bottom of the inner wall of the box body (1) are respectively fixedly and alternately connected with two water-cooled tubes (18), the two water-cooled tubes (18) are arranged in a U shape, and the two water-cooled tubes (18) are distributed with the stirring blades (63) in a staggered manner.

5. The processing equipment for high purity NAD production according to claim 1, characterized in that: a second filter screen (14) is fixedly arranged on one side of the bottom end of the inner wall of the box body (1), and the position of the second filter screen (14) corresponds to the position of one of the discharge pipes (12).

6. The processing equipment for high purity NAD preparation according to claim 3, characterized in that: the four corners of box (1) bottom is all fixed and is equipped with supporting leg (15), the top and the bottom of box (1) avris inlay respectively and be equipped with two transparent windows (16), the middle part of box (1) avris is fixed and is equipped with flush mounting plate (17), flush mounting plate (17) surface is installed first solenoid valve control switch, electric heat bar control switch, motor control switch, second solenoid valve control switch, circulation control switch, electric tee valve control switch and two third solenoid valve control switches respectively, first solenoid valve (4), two sets of electric heat bar (5), two motors (61), second solenoid valve (9), circulating pump (101), electric tee valve (104) and two third solenoid valves (13) are respectively through first solenoid valve control switch, two electric heat bar control switches, two motor control switches, second solenoid valve control switch, The circulation control switch, the electric three-way valve control switch and the two third electromagnetic valve control switches are electrically connected with an external power supply.