CN214049208U - Mouse brain irradiation fixing device with air bag and motion monitoring function - Google Patents
Mouse brain irradiation fixing device with air bag and motion monitoring function Download PDFInfo
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- CN214049208U CN214049208U CN202022615762.6U CN202022615762U CN214049208U CN 214049208 U CN214049208 U CN 214049208U CN 202022615762 U CN202022615762 U CN 202022615762U CN 214049208 U CN214049208 U CN 214049208U
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- side wall
- fixing device
- blocking block
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Abstract
The utility model discloses a mouse brain irradiation fixing device with an air bag and motion monitoring, which comprises a U-shaped accommodating bin and baffles arranged at two ends, wherein the left side wall and the right side wall of the U-shaped accommodating bin are symmetrical; a second sliding groove and a third sliding groove are sequentially arranged above the inner side surface of the side wall from top to bottom; a first lead blocking block is arranged in each of the second sliding chute and the third sliding chute in a sliding manner, and two sides of the first lead blocking block are connected with the left side wall and the right side wall in a sliding manner; one end of the first lead blocking block is provided with a notch; an air bag is arranged below the inner side of the side wall; the air bag is connected with the inflation and deflation device. The utility model discloses a setting up of gasbag makes the fixed simple more swift of mouse, realizes that the large tracts of land of mouse side is fixed, and is fixed effectual, can also control inflation pressure through filling and deflating device, guarantees the effect uniformity when repeated fixing.
Description
Technical Field
The utility model relates to a medical science mouse experimental facilities technical field especially involves a take gasbag and motion monitoring's mouse brain to shine fixing device.
Background
Tumor radiotherapy is a local treatment for tumors using radiation. About 70% of cancer patients require radiation therapy in the course of cancer treatment, and about 40% of cancers can be cured by radiation therapy. To investigate the effects of radiation on tumor or normal tissues and organisms, animal models are usually created and further irradiation is performed for study purposes, including live imaging of small animals and follow-up experiments.
With the development of minimally invasive medicine, precise radiotherapy is gradually regarded as one of three treatment modes, and especially, head and neck tumors such as glioma, nasopharyngeal carcinoma, brain metastasis tumor and the like have wide application and good effect. The radioactive brain injury is a common and serious complication of head and neck radiotherapy, and in order to better research the occurrence mechanism of the radioactive brain injury, animal experiments cannot be deleted, and mice are common experimental animals. However, because the mouse is small in size and difficult to fix, the mouse is often placed simply, so that the experimental precision is not high, and the effect of accurate radiotherapy cannot be achieved. In addition, the method of single or few large dose divided treatments developed in recent years requires a long irradiation time for the mouse in the mouse experiment.
Mice are one of the most commonly used experimental animals and have gained importance in studies related to tumor radiotherapy. Generally, a mouse needs to be anesthetized, and then a specific part is irradiated according to a research purpose, the anesthetized mouse is easy to translocate due to the fact that the body is soft and difficult to fix, accurate irradiation of a certain body part is difficult, inaccurate irradiation causes inaccurate results of experiments, and translocation in an imaging process causes unsuccessful image acquisition. Meanwhile, if the time is long, the activity of the mouse can influence the irradiation effect after the anesthesia is invalid.
Mice are commonly used experimental animals in radioactive brain injury animal experiments. The conventional method is to place the device in a fixture for irradiation after anesthesia. There are problems in that the body of the mouse is soft after anesthesia, it is difficult to fix, and the mouse is easily waken up. The existing fixing device cannot be completely suitable for the size of a mouse and has gaps. The mouse may wake up in the long-time irradiation process, and if the mouse is not found to be awake in time, the irradiation failure and the time waste can be caused. For example, a dose of 70G requires 66 minutes on an animal irradiation device, during which the mouse may wake up, which affects the accuracy of irradiation and fails to achieve the desired result. In addition, on the exposure mode of the mouse irradiation field, the current common mode of manually placing the lead block exists, the conditions of easy sliding and inaccurate positioning exist, and the improvement is needed.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to overcome the weak point among the above-mentioned prior art and provide a simple structure, it is fixed firm, can monitor mouse activity take gasbag and motion monitoring's mouse brain to shine fixing device.
The utility model discloses a realize through following mode:
the utility model provides a take gasbag and motion monitoring's mouse brain to shine fixing device, holds the baffle that storehouse and both ends set up including the U-shaped, its characterized in that: the left side wall and the right side wall of the U-shaped accommodating bin are symmetrical; a second sliding groove and a third sliding groove are sequentially arranged above the inner side surface of the side wall from top to bottom; a first lead blocking block is arranged in each of the second sliding chute and the third sliding chute in a sliding manner, and two sides of the first lead blocking block are connected with the left side wall and the right side wall in a sliding manner; one end of the first lead blocking block is provided with a notch; an air bag is arranged below the inner side of the side wall; the air bag is connected with the inflation and deflation device.
Furthermore, the baffle is provided with air holes.
Furthermore, the middle part of the baffle is provided with an elongated slot.
Furthermore, a first sliding groove is formed in the top of the side wall; a second lead block is connected in the first sliding chute in a sliding manner; the width of the second lead blocking block is smaller than half of the width of the U-shaped containing bin.
Further, the first sliding groove is a T-shaped groove.
Further, the length of the second lead blocking block is more than or equal to two times of the maximum value of the U-shaped accommodating bin in the length direction.
Furthermore, the shape of the gap is an isosceles right triangle; and scale indicating lines are arranged on two side edges of the notch.
Furthermore, the notches of the first lead blocking blocks in the second sliding groove and the third sliding groove are arranged oppositely.
Further, a motion detection camera is arranged on the lower surface of a first lead blocking block arranged in the third sliding chute; the motion detection camera is arranged near the notch; the motion detection camera is connected with an alarm.
Furthermore, arc-shaped elastic metal sheets are arranged on two side edges of the first lead blocking block.
The beneficial effects of the utility model reside in that:
1. the position and the size that the control mouse that can be random shines through the setting of first fender lead pig, the structure of arc elastic metal piece makes first fender lead pig can be fixed in optional position when sliding in second spout or third spout simultaneously, convenient operation.
2. The setting up of gasbag makes the fixed simple more swift of mouse, realizes that the large tracts of land of mouse side is fixed, and is fixed effectual, can also control inflation pressure through inflating and deflating the device, guarantees the effect uniformity when repeated fixing.
3. After the motion detection camera arranged below the first lead blocking block is connected with the alarm, the movement of a mouse can be detected, the alarm is given, and the special condition can be quickly responded.
4. The scale indication lines arranged on the gaps and the shapes of the gaps can quickly calculate the area of the irradiation area.
5. The second lead blocking block can be matched with the first lead blocking block, the irradiation area is adjusted for the second time, and more irradiation requirements are met.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
Fig. 1 is a schematic view of the U-shaped storage bin of the present invention.
Fig. 2 is a perspective view of the U-shaped storage chamber of the present invention.
Fig. 3 is a schematic structural view of embodiment 1 of the present invention.
Fig. 4 is a schematic structural view of embodiment 2 of the present invention.
Fig. 5 is a schematic structural view of embodiment 3 of the present invention.
Fig. 6 is a schematic structural view of embodiment 4 of the present invention.
Fig. 7 is a schematic structural view of a U-shaped accommodating chamber in embodiment 4 of the present invention.
Fig. 8 is a schematic structural view of the first lead blocking block of the present invention.
Detailed Description
To make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the drawings of the embodiments of the present invention are combined to clearly and completely describe the technical solutions of the embodiments of the present invention, and obviously, the described embodiments are some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention. Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "both ends", "one end", "the other end" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element to which the reference is made must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "provided," "connected," and the like are to be construed broadly, and for example, "connected" may be either fixedly connected or detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
The first embodiment is as follows:
as shown in fig. 1-3, a mouse brain irradiation fixing device with an air bag and motion monitoring comprises a U-shaped accommodating chamber 1 and baffles 2 arranged at two ends, and is characterized in that: the left side wall 3 and the right side wall 3 of the U-shaped accommodating bin 1 are symmetrical; a second sliding groove 5 and a third sliding groove 6 are sequentially arranged above the inner side surface of the side wall 3 from top to bottom; a first lead blocking block 7 is arranged in each of the second sliding chute 5 and the third sliding chute 6 in a sliding manner, and two sides of the first lead blocking block 7 are connected with the left side wall 3 and the right side wall 3 in a sliding manner; a notch 71 is formed at one end of the first lead blocking block 7; an air bag 9 is arranged below the inner side of the side wall 3; the air bag 9 is connected with an air charging and discharging device.
As shown in fig. 8, two sides of the first lead blocking block 7 are provided with arc-shaped elastic metal sheets 72; the shape of the gap 71 is an isosceles right triangle; and scale indicating lines are arranged on two side edges of the notch 71.
Furthermore, the second sliding chute 5 and the notch 71 of the first lead blocking block 7 in the third sliding chute 6 are arranged oppositely.
Further, a motion detection camera is arranged on the lower surface of a first lead block 7 arranged in the third sliding chute 6; the motion detection camera is arranged near the gap 71; the motion detection camera is connected with an alarm.
The irradiation area is square in the embodiment, local irradiation of a certain section of the whole body of the mouse can be carried out on the mouse according to requirements, and the irradiation area can be fixed and moved quickly. The arc-shaped elastic metal sheet 72 is a semicircular elastic sheet and can be fixed on the side of the first lead block 7 through a strip-shaped clamping groove or a fixing piece. The setting of arc elastic metal piece 72 makes first fender lead 7 remove in second spout 5, third spout 6 when, very big increase the frictional force between side and the lateral wall 3, and arc elastic metal piece 72 is in the extrusion deformation state when using always, therefore both sides exert pressure to lateral wall 3 always, can fix when not exerting external force push-and-pull, convenient and fast's realization optional position fixed. The motion detection camera is arranged by a conventional means in the prior art, and only needs to alarm after detecting the movement of the mouse, so that the shooting distance is not long, the requirement on equipment is not high, and technicians in the field can have many choices, and the working principle of the motion detection camera is well known in the field, so the specific structure of the motion detection camera is not described in detail.
Example two:
as shown in fig. 4, a take gasbag and motion monitoring's mouse brain to shine fixing device, including the baffle 2 that U-shaped holds storehouse 1 and both ends setting, its characterized in that: the left side wall 3 and the right side wall 3 of the U-shaped accommodating bin 1 are symmetrical; a second sliding groove 5 and a third sliding groove 6 are sequentially arranged above the inner side surface of the side wall 3 from top to bottom; a first lead blocking block 7 is arranged in each of the second sliding chute 5 and the third sliding chute 6 in a sliding manner, and two sides of the first lead blocking block 7 are connected with the left side wall 3 and the right side wall 3 in a sliding manner; the notches 71 of the first lead blocking blocks 7 in the second sliding chute 5 and the third sliding chute 6 are oppositely arranged; a motion detection camera is arranged on the lower surface of the first lead blocking block 7 arranged in the third sliding chute 6; the motion detection camera is arranged near the gap 71; the motion detection camera is connected with an alarm; a notch 71 is formed at one end of the first lead blocking block 7; an air bag 9 is arranged below the inner side of the side wall 3; the air bag 9 is connected with an air charging and discharging device.
Further, a first sliding groove 4 is formed in the top of the side wall 3; the first sliding groove 4 is a T-shaped groove; a second lead block 8 is connected in the first sliding chute 4 in a sliding manner; the width of the second lead blocking block 8 is less than half of the width of the U-shaped containing bin 1; the length of the second lead blocking block 8 is more than or equal to twice of the maximum value of the U-shaped containing bin 1 in the length direction.
As shown in fig. 8, two sides of the first lead blocking block 7 are provided with arc-shaped elastic metal sheets 72; the shape of the gap 71 is an isosceles right triangle; scale indicating lines are arranged on two side edges of the notch 71;
the difference between this embodiment and embodiment 1 is that the sidewall 3 is connected with a second lead stopper 8 through the first sliding groove 4, and after being matched with the first lead stopper 7, more accurate irradiation can be realized. Generally, the irradiation to the brain of the mouse is used, the left half brain or the right half brain of the mouse can be shielded by the second lead blocking block 8 during irradiation, so that the brain is accurately irradiated in a subarea manner, and the irradiation precision and the irradiation effect can be improved.
Example three:
as shown in fig. 5 and 7, in this embodiment, the baffle 2 is provided with an air hole 10, and the middle of the other baffle 2 on the opposite side is provided with an elongated slot 11; the top of the side wall 3 is provided with a first sliding chute 4; the first sliding groove 4 is a T-shaped groove; a second lead block 8 is connected in the first sliding chute 4 in a sliding manner; the width of the second lead blocking block 8 is less than half of the width of the U-shaped containing bin 1; the length of the second lead blocking block 8 is more than or equal to twice of the maximum value of the U-shaped containing bin 1 in the length direction.
As shown in fig. 8, two sides of the first lead blocking block 7 are provided with arc-shaped elastic metal sheets 72; the shape of the gap 71 is an isosceles right triangle; and scale indicating lines are arranged on two side edges of the notch 71.
Further, the notches 71 of the first lead blocking blocks 7 in the second sliding chute 5 and the third sliding chute 6 are oppositely arranged; a motion detection camera is arranged on the lower surface of the first lead blocking block 7 arranged in the third sliding chute 6; the motion detection camera is arranged near the gap 71; the motion detection camera is connected with an alarm.
The difference between the embodiment and the embodiment 3 is that the baffle 2 is provided with an air hole or a long groove 11; the long groove 11 can facilitate the tail placement of a mouse and the irradiation of a larger mouse.
Example four:
as shown in fig. 6-8, in this embodiment, the baffle 2 is provided with an air hole 10, and the middle of the other baffle 2 on the opposite side is provided with an elongated slot 11; the top of the side wall 3 is provided with a first sliding chute 4; the first sliding groove 4 is a T-shaped groove; a second lead block 8 is connected in the first sliding chute 4 in a sliding manner; the width of the second lead blocking block 8 is less than half of the width of the U-shaped containing bin 1; the length of the second lead blocking block 8 is more than or equal to twice of the maximum value of the U-shaped accommodating bin 1 in the length direction; two sides of the first lead blocking block 7 are provided with arc-shaped elastic metal sheets 72; the shape of the gap 71 is an isosceles right triangle; scale indicating lines are arranged on two side edges of the notch 71; a motion detection camera is arranged on the lower surface of the first lead blocking block 7 arranged in the third sliding chute 6; the motion detection camera is arranged near the gap 71; the motion detection camera is connected with an alarm.
In this embodiment, two first lead blocking blocks are arranged in the same direction, and the irradiation area is triangular, so that the requirements of some special cases can be met.
In an embodiment of the present invention, the shape of the notch 71 may be a shape that can satisfy the irradiation requirement, such as a semi-arc shape, an arc shape, or a square shape.
The utility model discloses an in the embodiment, the length direction of second fender lead 8 indicates the upper and lower direction in the drawing, and the length of second fender lead 8 also can set up according to the demand. The second lead blocking block 8 is mainly used for secondary shielding, and an arc-shaped elastic metal sheet can be arranged in a sliding block at the bottom of the second lead blocking block 8 to fix any position.
The utility model discloses an in the embodiment, the slight prominence that shape one end of gasbag 9 set up to the head shape of better cooperation mouse side, fixed effect is better.
The utility model discloses a position and size that the control mouse that setting up of first fender lead block can be random shines, and arc elastic metal piece's structure makes first fender lead block can be fixed at optional position when sliding in second spout or third spout simultaneously, convenient operation. The setting up of gasbag makes the fixed simple more swift of mouse, realizes that the large tracts of land of mouse side is fixed, and is fixed effectual, can also control inflation pressure through inflating and deflating the device, guarantees the effect uniformity when repeated fixing. After the motion detection camera arranged below the first lead blocking block is connected with the alarm, the movement of a mouse can be detected, the alarm is given, and the special condition can be quickly responded. The scale indication lines arranged on the gaps and the shapes of the gaps can quickly calculate the area of the irradiation area. The second lead blocking block can be matched with the first lead blocking block, the irradiation area is adjusted for the second time, and more irradiation requirements are met.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. The utility model provides a take gasbag and motion monitoring's mouse brain to shine fixing device, holds baffle (2) that storehouse (1) and both ends set up including the U-shaped, its characterized in that: the left side wall and the right side wall (3) of the U-shaped containing bin (1) are mutually symmetrical; a second sliding chute (5) and a third sliding chute (6) are sequentially arranged above the inner side surface of the side wall (3) from top to bottom; a first lead blocking block (7) is arranged in each of the second sliding chute (5) and the third sliding chute (6) in a sliding manner, and two sides of the first lead blocking block (7) are connected with the left side wall and the right side wall (3) in a sliding manner; one end of the first lead blocking block (7) is provided with a notch (71); an air bag (9) is arranged below the inner side of the side wall (3); the air bag (9) is connected with an air charging and discharging device.
2. The mouse brain irradiation fixing device with the air bag and the movement monitoring function according to claim 1, wherein: the baffle (2) is provided with air holes (10).
3. The mouse brain irradiation fixing device with the air bag and the movement monitoring function according to claim 1, wherein: the middle part of the baffle (2) is provided with a long groove (11).
4. The mouse brain irradiation fixing device with the air bag and the movement monitoring function according to claim 1, wherein: the top of the side wall (3) is provided with a first sliding chute (4); a second lead block (8) is connected in the first sliding chute (4) in a sliding manner; the width of the second lead blocking block (8) is less than half of the width of the U-shaped accommodating bin (1).
5. The mouse brain irradiation fixing device with the air bag and the movement monitoring function according to claim 4, wherein: the length of the second lead blocking block (8) is more than or equal to twice of the maximum value of the U-shaped containing bin (1) in the length direction.
6. The mouse brain irradiation fixing device with the air bag and the movement monitoring function according to claim 4, wherein: the first sliding groove (4) is a T-shaped groove.
7. The mouse brain irradiation fixing device with the air bag and the movement monitoring function according to claim 1, wherein: the shape of the gap (71) is an isosceles right triangle; and scale indicating lines are arranged on two side edges of the notch (71).
8. The mouse brain irradiation fixing device with the air bag and the movement monitoring function according to claim 1, wherein: the second sliding groove (5) and the notch (71) of the first lead blocking block (7) in the third sliding groove (6) are arranged oppositely.
9. The mouse brain irradiation fixing device with the air bag and the movement monitoring function according to claim 1, wherein: a motion detection camera is arranged on the lower surface of a first lead block (7) arranged in the third sliding chute (6); the motion detection camera is arranged near the gap (71); the motion detection camera is connected with an alarm.
10. The mouse brain irradiation fixing device with the air bag and the movement monitoring function according to claim 1, wherein: and arc-shaped elastic metal sheets (72) are arranged on two side edges of the first lead blocking block (7).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022615762.6U CN214049208U (en) | 2020-11-12 | 2020-11-12 | Mouse brain irradiation fixing device with air bag and motion monitoring function |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022615762.6U CN214049208U (en) | 2020-11-12 | 2020-11-12 | Mouse brain irradiation fixing device with air bag and motion monitoring function |
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| Publication Number | Publication Date |
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| CN214049208U true CN214049208U (en) | 2021-08-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202022615762.6U Active CN214049208U (en) | 2020-11-12 | 2020-11-12 | Mouse brain irradiation fixing device with air bag and motion monitoring function |
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