CN213955778U - A intelligent drying cabinet for preparing reorganization fibronectin freeze-dried powder - Google Patents
A intelligent drying cabinet for preparing reorganization fibronectin freeze-dried powder Download PDFInfo
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- CN213955778U CN213955778U CN202022789640.9U CN202022789640U CN213955778U CN 213955778 U CN213955778 U CN 213955778U CN 202022789640 U CN202022789640 U CN 202022789640U CN 213955778 U CN213955778 U CN 213955778U
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Abstract
The utility model relates to a drying equipment technical field specifically relates to an intelligent drying cabinet for preparing reorganization fibronectin freeze-dried powder, including: the refrigerator comprises a box body, a first sealing box door is arranged at one end of the box body, a second sealing box door is arranged at the adjacent side of the box body, refrigerating plates are arranged in the box body and close to the two sides of the first sealing box door, and a first working pipe and a second working pipe which are communicated with a vacuum pump and a cold trap are respectively arranged at the top end of the box body; the visual detection mechanism is arranged inside the box body; the translation assembly is arranged at the bottom end in the box body and comprises a transparent placing plate, and placing openings are uniformly distributed in the transparent placing plate; the working end of the lower pressing device is vertically arranged in the box body in a penetrating mode, and a first magnet is arranged on the bottom face of the working end of the lower pressing device; the adjustable-spacing type placing rack is characterized in that second magnets which are mutually attracted with the first magnets are arranged on two sides of the top end of the placing rack; the temperature probe is arranged inside the box body, and the device can automatically adjust the temperature according to the freeze-drying condition of the albumen powder in the bottle.
Description
Technical Field
The utility model relates to a drying equipment technical field specifically relates to an intelligent drying cabinet for preparing restructural fibronectin freeze-dried powder.
Background
Vacuum freeze-drying (hereinafter, referred to as "lyophilization") refers to a method of freezing a water-containing substance into a solid state in advance, and then sublimating water therein from the solid state into a gaseous state under a vacuum state to remove water and preserve the substance. The solid matter after freeze-drying is in a porous structure, the volume of the solid matter during freezing is kept, and the solid matter is very easy to dissolve and recover after being added with water. The lyophilization process is performed under low temperature vacuum conditions and is therefore particularly useful for many heat sensitive, easily oxidized substances. The freeze-drying can remove 95-99% of water, so that the dried product can be stored for a long time.
Interferon is a broad-spectrum antiviral agent, and can inhibit virus replication by reacting with cell surface receptor to make cell produce antiviral protein; meanwhile, the activity of natural killer cells (NK cells), macrophages and T lymphocytes can be enhanced, so that the immune regulation effect is achieved, and the antiviral capacity is enhanced. The product has the problems of poor thermal stability of liquid dosage forms, difficult long-term storage and the like when being applied to the production practice of animal husbandry and veterinary medicine. The ideal solution is to freeze-dry the product, which not only prolongs the shelf life, but also facilitates transportation.
Chinese patent CN201310526180.2 discloses a freeze-drying method of recombinant porcine interferon alpha products, which comprises processes of pre-freezing, recrystallization, primary drying, secondary drying, sublimation and the like of rPoIFN alpha 1 stock solution.
A drying box is needed in the freeze-drying method, and the existing drying box is not suitable for the method and cannot be dried intelligently.
SUMMERY OF THE UTILITY MODEL
In order to solve the technical problems, the technical scheme solves the intelligent drying problem of the recombinant fibronectin freeze-dried powder.
In order to achieve the above purpose, the utility model adopts the technical scheme that:
an intelligent drying oven for preparing recombinant fibronectin freeze-dried powder, comprising: the refrigerator comprises a box body, a first sealing box door is arranged at one end of the box body, a second sealing box door is arranged at the adjacent side of the box body, refrigerating plates are arranged in the box body and close to the two sides of the first sealing box door, and a first working pipe and a second working pipe which are communicated with a vacuum pump and a cold trap machine are respectively arranged at the top end of the box body; the working end of the visual detection mechanism is arranged in the box body downwards and is positioned at the top of the refrigeration plate; the translation assembly is arranged at the bottom end in the box body and comprises a transparent placing plate capable of horizontally sliding, and placing openings with vertical axes and inner diameters not smaller than those of the bottle bodies are uniformly distributed in the transparent placing plate; the working end of the lower pressing device is vertically arranged in the box body in a penetrating mode, and first magnets are arranged on the bottom surface of the working end of the lower pressing device at equal intervals along two sides of the moving direction of the translation assembly; the adjustable-spacing type placing frame is provided with second magnets which attract the first magnets at two sides of the top end of the adjustable-spacing type placing frame, the adjustable-spacing type placing frame and the second sealing box door are in the same vertical plane, and the adjustable-spacing type placing frame is used for uniformly distributing bottle caps in the same distribution as the placing opening; and the working end of the temperature probe vertically penetrates through the first sealing box door and is arranged in the box body, and the temperature probe is electrically connected with the control circuit.
Preferably, the visual inspection mechanism comprises: the notch of the feeding type transparent partition plate is arranged at the top end in the box body towards the working end of the translation assembly; light filling lamp and camera, light filling lamp and camera all incline and place the board setting at the transparent baffle both sides top of feeding type towards transparent, the camera is connected with the controller electricity.
Preferably, the translation assembly further comprises: the guide rails are arranged at the bottom end inside the box body side by side; the fixed plate is horizontally arranged at the top end of the guide rail sliding block; the axes of the upright columns are vertically arranged at four corners of the top end of the fixed plate, and the transparent placing plate and the fixed plate are arranged at the top of the fixed plate in parallel through the upright columns; the roller chain assembly is arranged at the top end inside the box body along the sliding direction of the guide rail, and the top end of the roller chain assembly is fixedly connected with the bottom end of the fixing plate; the rotating shaft horizontally penetrates through the box body and is coaxially and fixedly connected with a chain wheel at one end of the roller chain assembly; and an output shaft of the servo motor is coaxially and fixedly connected with one end of the rotating shaft.
Preferably, the presser further comprises: the output shaft of the double-shaft cylinder penetrates through the top end of the box body and is arranged at the bottom end of the box body; the lower pressing plate is horizontally arranged at the bottom end of the output shaft of the double-shaft air cylinder, ladder edges convenient for installation of first magnets are arranged on the two sides, perpendicular to the moving direction, of the bottom end of the lower pressing plate, and the bottom end of each first magnet is flush with the bottom end of the lower pressing plate.
Preferably, adjustable interval formula rack is still including: the second magnets are arranged on two sides of the top end of the fixed frame at equal intervals; the sliding rods are arranged in the second magnet inner frame side by side; the clamping rod and the sliding rod vertically slide relative to each other and are arranged in the fixing frame at equal intervals, the sliding rod penetrates through the first clamping rod and is in sliding fit with the first clamping rod, and a first arc groove and a second arc groove are respectively and evenly distributed on the opposite sides of the first clamping rod and the second clamping plate at equal intervals; the nut and the sliding rod are coaxially arranged on two sides of the clamping plate respectively, and the nuts are coaxial; the lead screw, the lead screw rotates with the slide bar is coaxial and sets up on fixed frame, the lead screw with the coaxial normal running fit of nut, just the coaxial fixed screw thread that is provided with in lead screw both ends.
Preferably, adjustable interval formula rack is still including semicircle limiting plate, semicircle limiting plate coaxial setting first arc groove and second arc groove top, and semicircle limiting plate internal diameter is greater than arc groove internal diameter.
Compared with the prior art, the invention has the beneficial effects that:
the drying box can monitor the freeze-drying condition in real time, can perform capping in a vacuum environment, and specifically, before work, bottle caps are uniformly distributed between a first clamping rod and a second clamping plate, a lead screw is rotated to enable the first clamping rod and the second clamping plate to uniformly clamp the bottle caps, a second sealing box door is opened, an adjustable-spacing type placing frame provided with the bottle caps is arranged in a box body through the second sealing box door, a second magnet and a fixing frame are attracted with each other, so that the horizontal magnetic attraction of the adjustable-spacing type placing frame provided with the bottle caps is arranged at the bottom end of a working part of a depressor, and the second sealing box door is closed; opening the first sealing box door, inserting the bottle filled with the stock solution into the placing opening, starting the servo motor, enabling the rotating shaft to drive the roller chain assembly chain wheel to rotate, enabling the transparent placing plate to drive the bottle to slide in the box body, and closing the first sealing box door; the refrigeration plate is used for controlling the internal temperature of the box body, the temperature probe is used for monitoring the internal temperature of the box body in real time, the first working pipe and the second working pipe are respectively connected with the vacuum pump and work, the raw liquid is subjected to freeze-drying operation according to the freeze-drying method of the recombinant porcine interferon alpha product disclosed by the Chinese patent CN201310526180.2, and in the process, the position of a dry surface of protein powder in a bottle can be monitored in real time through the visual detection mechanism, so that accurate freeze-drying is facilitated; after the freeze-drying is finished, a gland is required to be pressed in the box body, a servo motor is started, the transparent placing plate drives the bottle to translate to the bottom of the drying end of the lower pressing device, the double-shaft cylinder is started, the working end of the double-shaft cylinder drives the adjustable-interval type placing frame to vertically press downwards, the bottle cap is pressed on the bottle opening, the pressing state of the double-shaft cylinder is kept, the working end of the translation assembly is reset, the first magnet and the double-shaft cylinder are enabled to be staggered and separated from each other, and the adjustable-interval type placing frame is located at the top of the transparent placing plate; the vacuum is released, the first sealing box door is opened, the second magnet is lifted, all the bottles are separated from the placing openings, the bottles filled with the protein powder in a sealing mode are taken down from the transparent placing plate, the lead screw is turned over and rotated, the distance between the first arc groove and the second arc groove is larger than the diameter of the bottle cap, the bottles can be separated from the adjustable-distance type placing frame, and therefore centralized processing is facilitated; compare current drying cabinet, this drying cabinet freeze-drying effect of more accurate observation is convenient for the closing cap under vacuum environment.
Drawings
FIG. 1 is a perspective view of the box body of the present invention in a perspective state;
fig. 2 is a front view of the present invention;
fig. 3 is a perspective view of the hold-down device of the present invention;
fig. 4 is a front view of the lower press of the present invention;
fig. 5 is a perspective view of the adjustable-pitch rack of the present invention;
fig. 6 is a partially enlarged view of fig. 5 at a.
The reference numbers in the figures are:
1-a box body; 1 a-a first sealed box door; 1 b-a second sealed box door; 1 c-a refrigeration plate; 1 d-a first working tube; 1 e-a second working tube;
2-a visual inspection mechanism; 2 a-a feeding type transparent partition plate; 2 b-a light supplement lamp; 2 c-a camera;
3-a translation assembly; 3 a-a transparent placing plate; 3a 1-place port; 3 b-a guide rail; 3 c-fixing the plate; 3 d-column; 3 e-a roller chain assembly; 3 f-a rotating shaft; 3 g-servo motor;
4-pressing down the device; 4 a-a first magnet; 4 b-a two-axis cylinder; 4 c-a lower platen; 4c 1-step edge;
5-adjustable spacing type placing rack; 5 a-a second magnet; 5 b-a fixed frame; 5 c-a slide bar; 5 d-a first clamping bar; 5d1 — first arc groove; 5 e-a second clamping plate; 5e1 — second arc groove; 5 f-first nut; 5 g-second thread; 5 h-screw mandrel; 5h 1-fixed threads; 5 i-a semicircular limiting plate;
6-temperature probe.
Detailed Description
The following description is presented to disclose the invention so as to enable any person skilled in the art to practice the invention. The preferred embodiments in the following description are given by way of example only, and other obvious variations will occur to those skilled in the art.
Referring to fig. 1, a smart dry box for preparing recombinant fibronectin lyophilized powder includes:
the refrigerator comprises a box body 1, wherein one end of the box body 1 is provided with a first sealed box door 1a, the adjacent side of the box body is also provided with a second sealed box door 1b, the inside of the box body 1, which is close to the two sides of the first sealed box door 1a, is provided with a refrigerating plate 1c, and the top end of the box body 1 is also respectively provided with a first working pipe 1d and a second working pipe 1e which are communicated with a vacuum pump and a cold trap machine;
the working end of the visual detection mechanism 2 is downwards arranged in the box body 1 and positioned at the top of the refrigerating plate 1 c;
the translation assembly 3 is arranged at the bottom end in the box body 1, the translation assembly 3 comprises a transparent placing plate 3a capable of horizontally sliding, and placing openings 3a1 with vertical axes and inner diameters not smaller than those of the bottles are uniformly distributed on the transparent placing plate 3 a;
the working end of the lower pressing device 4 is vertically arranged in the box body 1 in a penetrating mode, and first magnets 4a are arranged on the bottom surface of the working end of the lower pressing device 4 at equal intervals along two sides of the moving direction of the translation assembly 3;
the adjustable-spacing type placing frame 5 is characterized in that second magnets 5a which attract the first magnets 4a are arranged on two sides of the top end of the adjustable-spacing type placing frame 5, the adjustable-spacing type placing frame 5 and the second sealing box door 1b are in the same vertical plane, and bottle caps are uniformly distributed on the adjustable-spacing type placing frame 5 and are distributed at the same position as the placing opening 3a 1;
and the working end of the temperature probe 6 vertically penetrates through the first sealing box door 1a and is arranged inside the box body 1, and the temperature probe 6 is electrically connected with the control.
Before work, the bottle caps are uniformly distributed on the adjustable-spacing type placing frame 5, the second sealing box door 1b is opened, the adjustable-spacing type placing frame 5 provided with the bottle caps is arranged in the box body 1 through the second sealing box door 1b, so that the second magnet 5a and the fixing frame 5b are attracted with each other, the adjustable-spacing type placing frame 5 provided with the bottle caps is horizontally magnetically attracted to the bottom end of the working part of the lower pressure device 4, and the second sealing box door 1b is closed; opening the first sealing box door 1a, inserting the bottle filled with the stock solution into the placing port 3a1, so that the transparent placing plate 3a can drive the bottle to slide in the box body 1, and closing the first sealing box door 1 a;
the refrigeration plate 1c is used for controlling the internal temperature of the box body 1, the temperature probe 6 is used for monitoring the internal temperature of the box body 1 in real time, the first working pipe 1d and the second working pipe 1e are respectively connected with a vacuum pump and work, the raw liquid is subjected to freeze-drying operation according to a freeze-drying method of a recombinant porcine interferon alpha 1 product disclosed by Chinese patent CN201310526180.2, and in the process, the position of a dry surface of protein powder in a bottle can be monitored in real time through the visual detection mechanism 2, so that accurate freeze-drying is facilitated;
after the freeze-drying is finished, a gland needs to be pressed in the box body 1, the translation assembly 3 is started, the transparent placing plate 3a drives the bottle to translate to the bottom of the drying end of the lower pressing device 4, the lower pressing device 4 is started, the working end of the lower pressing device 4 drives the adjustable-interval type placing frame 5 to vertically press down, the bottle cap is pressed on the bottle mouth in a propping manner, the pressing state of the working end of the lower pressing device 4 is kept, the working end of the translation assembly 3 is reset, the first magnet 4a and the double-shaft cylinder 4b are staggered and separated from each other, and the adjustable-interval type placing frame 5 is located at the top of the transparent placing plate 3 a;
put the vacuum, open first sealed chamber door 1a, lift adjustable interval formula rack 5 for all bottles break away from and place mouthful 3a1, thereby the bottle that will seal and be equipped with albumen powder takes off from transparent board 3a of placing, readjusts the 5 work ends distances of adjustable interval formula rack, makes the bottle can break away from adjustable interval formula rack 5, thereby the centralized processing of being convenient for.
As shown in fig. 2, the visual inspection mechanism 2 includes:
the notch of the feeding type transparent partition plate 2a is arranged at the top end in the box body 1 towards the working end of the translation assembly 3;
In freeze-drying process, start light filling lamp 2b and can make 1 inside bottle of box visual, start camera 2c, can directly pass and feed type transparent baffle 2a and survey dry face in to the bottle, the intelligent control temperature of being convenient for, and feed type transparent baffle 2a and can prevent that the interior utmost point low temperature state of box 1 from damaging light filling lamp 2b and camera 2c, and because of feeding type transparent baffle 2a structural feature, make and feed type transparent baffle 2a slot part both sides and be difficult for the frost, thereby make to survey more accurate.
As shown in fig. 2, the translation assembly 3 further includes:
the guide rails 3b are arranged at the bottom end inside the box body 1 side by side;
the fixed plate 3c is horizontally arranged at the top end of the sliding block of the guide rail 3 b;
the vertical columns 3d are vertically arranged at four corners of the top end of the fixed plate 3c in an axial line mode, and the transparent placing plate 3a and the fixed plate 3c are arranged at the top of the fixed plate 3c in parallel through the vertical columns 3d 0;
the roller chain assembly 3e is arranged at the top end inside the box body 1 along the sliding direction of the guide rail 3b, and the top end of the roller chain assembly 3e is fixedly connected with the bottom end of the fixing plate 3 c;
the rotating shaft 3f horizontally penetrates through the box body 1 and is coaxially and fixedly connected with a chain wheel at one end of the roller chain assembly 3 e;
and an output shaft of the servo motor 3g is coaxially and fixedly connected with one end of the rotating shaft 3 f.
When needs carry out the gland, start servo motor 3g, make its output shaft drive roller chain subassembly 3e sprocket coaxial rotation through axis of rotation 3f, thereby make roller chain subassembly 3e roller chain drive fixed plate 3c slide on guide rail 3b, thereby make the grafting place on board 3a the bottle remove to 4 work end bottoms of depressor on the transparent board of placing, thereby be convenient for carry out the gland to it, and the transparent board 3a of placing sets up at fixed plate 3c top through stand 3d, thereby make the bottle be difficult for sliding on fixed plate 3c and be convenient for observe the dry face position through the transparent board 3a of placing.
As shown in fig. 3 and 4, the press 4 further includes:
an output shaft of the double-shaft cylinder 4b penetrates through the top end of the box body 1 and is arranged at the bottom end of the box body 1;
the lower pressing plate 4c, the lower pressing plate 4c level sets up in biax cylinder 4b output shaft bottom, just the lower pressing plate 4c bottom is provided with the ladder edge 4c1 of being convenient for install first magnet 4a with translation subassembly 3 moving direction vertically both sides, first magnet 4a bottom and lower pressing plate 4c bottom parallel and level.
During the gland, adjustable interval formula rack 5 passes through the absorption of second magnet 5a in holding down plate 4c bottom, thereby start biax cylinder 4b, make its output shaft drive holding down plate 4c and adjustable interval formula rack 5 push down, thereby support the bottle lid at the bottleneck, and keep holding down plate 4c output shaft for output state, 3 work ends of translation subassembly drive bottle and adjustable interval formula rack 5 together reset, and first magnet 4a bottom and holding down plate 4c bottom parallel and level, thereby make first magnet 4a and biax cylinder 4b crisscross relatively, thereby make adjustable interval formula rack 5 be located 3 work ends tops of translation subassembly, thereby realize the gland under vacuum environment.
As shown in fig. 5 and 6, the adjustable-pitch rack 5 further includes:
the fixed frame 5b, the second magnet 5a is set up in the both sides of top end of the fixed frame 5b with equal interval;
the sliding rods 5c are arranged in the inner frame of the second magnet 5a side by side;
the clamping device comprises a first clamping rod 5d and a second clamping plate 5e, wherein the clamping rod and a sliding rod 5c are vertically arranged in a fixed frame 5b in a relative sliding mode at equal intervals, the sliding rod 5c penetrates through the first clamping rod 5d to be in sliding fit with the first clamping rod 5d, and opposite sides of the first clamping rod 5d and the second clamping plate 5e are respectively and uniformly provided with a first arc groove 5d1 and a second arc groove 5e1 at equal intervals;
the clamping plate comprises a first nut 5f and a second thread 5g, wherein the nuts and a sliding rod 5c are coaxially arranged on two sides of the clamping plate respectively, and the nuts are coaxial;
5h of lead screw, 5h of lead screw and the coaxial rotation of slide bar 5c set up on fixed frame 5b, 5h of lead screw with the coaxial normal running fit of nut, just the coaxial fixed set screw thread 5h1 that is provided with in 5h both ends of lead screw.
Before the work, the fixed screw thread 5h1 is rotated, make the lead screw 5h relatively fixed frame 5b rotate, and first nut 5f and second screw thread 5g intermeshing, thereby make first clamping bar 5d and second clamping plate 5e relatively slide on slide bar 5c, thereby be convenient for adjust the distance between first arc groove 5d1 and the second arc groove 5e1, thereby make the bottle lid can be by the centre gripping between first arc groove 5d1 and second arc groove 5e1, adsorb fixed frame 5b in depressor 4 working end bottom through second magnet 5a again, thereby be convenient for once with the bottle lid pressure equipment on the bottleneck.
As shown in fig. 6, the adjustable-pitch rack 5 further comprises a semicircular limiting plate 5i, the semicircular limiting plate 5i is coaxially provided with a first arc groove 5d1 and a second arc groove 5e1, and the inner diameter of the semicircular limiting plate 5i is larger than the inner diameter of the arc groove.
The working principle of the invention is as follows:
the device realizes the functions of the invention through the following steps, thereby solving the technical problems provided by the invention:
firstly, before work, bottle caps are uniformly distributed between a first clamping rod 5d and a second clamping plate 5e, a screw rod 5h is rotated to uniformly clamp the bottle caps by the first clamping rod 5d and the second clamping plate 5e, a second sealing box door 1b is opened, an adjustable-interval type placing frame 5 provided with the bottle caps is arranged in a box body 1 through the second sealing box door 1b, a second magnet 5a and a fixing frame 5b are attracted with each other, so that the adjustable-interval type placing frame 5 provided with the bottle caps is horizontally attracted to the bottom end of a working part of a depressor 4, and the second sealing box door 1b is closed; the first sealing box door 1a is opened, the bottle filled with the stock solution is inserted into the placing opening 3a1,
step two, starting the servo motor 3g, so that the rotating shaft 3f drives the roller chain component 3e to rotate by a chain wheel, and the transparent placing plate 3a can drive the bottles to slide in the box body 1, and closing the first sealing box door 1 a;
step three, the refrigeration plate 1c is used for controlling the internal temperature of the box body 1, the temperature probe 6 is used for monitoring the internal temperature of the box body 1 in real time, the first working pipe 1d and the second working pipe 1e are respectively connected with a vacuum pump and work, the raw liquid is subjected to freeze-drying operation according to a freeze-drying method of a recombinant porcine interferon alpha 1 product disclosed by Chinese patent CN201310526180.2, and in the process, the position of a dry surface of protein powder in a bottle can be monitored in real time through the visual detection mechanism 2, so that accurate freeze-drying is facilitated;
step four, after freeze-drying, pressing the cover in the box body 1, starting a servo motor 3g, enabling a transparent placing plate 3a to drive the bottle to move horizontally to the bottom of the drying end of a lower pressing device 4, starting a double-shaft cylinder 4b, enabling the working end of the double-shaft cylinder 4b to drive an adjustable-interval type placing frame 5 to vertically press downwards, enabling the bottle cover to be pressed on a bottle opening, meanwhile keeping the pressing state of the double-shaft cylinder 4b, driving the working end of a translation assembly 3 to reset, enabling a first magnet 4a and the double-shaft cylinder 4b to be mutually staggered and separated, and enabling the adjustable-interval type placing frame 5 to be located at the top of the transparent placing plate 3 a;
step five, putting off the vacuum, opening first seal chamber door 1a, lifting second magnet 5a to make all bottles break away from and place mouth 3a1, thereby will seal the bottle that is equipped with albumen powder and take off from transparent board 3a of placing, the lead screw 5h is rotated in the upset, make the interval between first arc groove 5d1 and the second arc groove 5e1 be greater than the bottle lid diameter, make the bottle can break away from adjustable interval formula rack 5, thereby be convenient for centralized processing.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the principles of the present invention may be applied to any other embodiment without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (6)
1. An intelligent drying oven for preparing recombinant fibronectin freeze-dried powder is characterized by comprising:
the refrigerator comprises a box body (1), wherein one end of the box body (1) is provided with a first sealing box door (1a), the adjacent side of the box body is also provided with a second sealing box door (1b), the inside of the box body (1) close to the two sides of the first sealing box door (1a) is provided with a refrigerating plate (1c), and the top end of the box body (1) is also respectively provided with a first working pipe (1d) and a second working pipe (1e) which are communicated with a vacuum pump and a cold trap machine;
the working end of the visual detection mechanism (2) is downwards arranged in the box body (1) and is positioned at the top of the refrigerating plate (1 c);
the bottle body placing device comprises a translation assembly (3), wherein the translation assembly (3) is arranged at the bottom end in the box body (1), the translation assembly (3) comprises a transparent placing plate (3a) capable of horizontally sliding, and placing openings (3a1) which are vertical in axis and not smaller than the bottle body in inner diameter are uniformly distributed in the transparent placing plate (3 a);
the working end of the lower pressing device (4) is vertically arranged in the box body (1) in a penetrating mode, and first magnets (4a) are arranged on the bottom surface of the working end of the lower pressing device (4) at equal intervals along two sides of the moving direction of the translation assembly (3);
the adjustable-spacing type placing frame (5) is characterized in that second magnets (5a) which attract the first magnets (4a) are arranged on two sides of the top end of the adjustable-spacing type placing frame (5), the adjustable-spacing type placing frame (5) and the second sealing box door (1b) are in the same vertical plane, and bottle caps are uniformly distributed on the adjustable-spacing type placing frame (5) and the placing opening (3a1) in the same distribution;
the temperature probe (6), temperature probe (6) work end runs through first sealed chamber door (1a) perpendicularly and sets up inside box (1), temperature probe (6) are connected with the control electricity.
2. The intelligent drying oven for preparing recombinant fibronectin lyophilized powder of claim 1, wherein the visual inspection mechanism (2) comprises:
the notch of the feeding type transparent partition plate (2a) is arranged at the top end in the box body (1) towards the working end of the translation assembly (3);
light filling lamp (2b) and camera (2c), light filling lamp (2b) and camera (2c) all incline and place board (3a) setting at feeding type transparent baffle (2a) both sides top towards transparent, camera (2c) are connected with the controller electricity.
3. The intelligent drying cabinet for preparing recombinant fibronectin lyophilized powder of claim 1, wherein the translation assembly (3) further comprises:
the guide rails (3b) are arranged at the bottom end inside the box body (1) side by side;
the fixing plate (3c) is horizontally arranged at the top end of the sliding block of the guide rail (3 b);
the vertical columns (3d) are vertically arranged at four corners of the top end of the fixing plate (3c), and the transparent placing plate (3a) and the fixing plate (3c) are arranged at the top of the fixing plate (3c) in parallel through the vertical columns (3d) 0;
the roller chain component (3e) is arranged at the top end of the interior of the box body (1) along the sliding direction of the guide rail (3b), and the top end of the roller chain component (3e) is fixedly connected with the bottom end of the fixing plate (3 c);
the rotating shaft (3f) horizontally penetrates through the box body (1) and is coaxially and fixedly connected with a chain wheel at one end of the roller chain assembly (3 e);
the output shaft of the servo motor (3g) is coaxially and fixedly connected with one end of the rotating shaft (3 f).
4. The intelligent drying box for preparing the recombinant fibronectin lyophilized powder as claimed in claim 1, wherein the depressor (4) further comprises:
the output shaft of the double-shaft cylinder (4b) penetrates through the top end of the box body (1) and is arranged at the bottom end of the box body (1);
lower plate (4c), lower plate (4c) level sets up in biax cylinder (4b) output shaft bottom, just lower plate (4c) bottom and translation subassembly (3) moving direction vertically both sides are provided with the ladder edge (4c1) of being convenient for install first magnet (4a), first magnet (4a) bottom and lower plate (4c) bottom parallel and level.
5. The intelligent drying oven for preparing recombinant fibronectin lyophilized powder of claim 1, wherein the adjustable-pitch rack (5) further comprises:
the fixed frame (5b), the second magnet (5a) is set up on both sides of top of the fixed frame (5b) with equal interval;
the sliding rods (5c) are arranged in the inner frame of the second magnet (5a) side by side;
the clamping device comprises a first clamping rod (5d) and a second clamping plate (5e), wherein the clamping rod and a sliding rod (5c) are vertically arranged in a fixed frame (5b) in a relative sliding mode at equal intervals, the sliding rod (5c) penetrates through the first clamping rod (5d) to be in sliding fit with the first clamping rod, and a first arc groove (5d1) and a second arc groove (5e1) are uniformly distributed on the opposite sides of the first clamping rod (5d) and the second clamping plate (5e) at equal intervals;
the clamping plate comprises a first nut (5f) and a second thread (5g), wherein the nuts and a sliding rod (5c) are coaxially arranged on two sides of the clamping plate respectively, and the nuts are coaxial;
lead screw (5h), lead screw (5h) and slide bar (5c) rotate with the axial and set up on fixed frame (5b), lead screw (5h) with the coaxial normal running fit of nut, just the coaxial fixed screw thread (5h1) that is provided with in lead screw (5h) both ends.
6. The intelligent drying oven for preparing the recombinant fibronectin freeze-dried powder is characterized in that the adjustable-pitch placing rack (5) further comprises a semicircular limiting plate (5i), the semicircular limiting plate (5i) is coaxially provided with the top ends of the first arc groove (5d1) and the second arc groove (5e1), and the inner diameter of the semicircular limiting plate (5i) is larger than that of the arc grooves.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022789640.9U CN213955778U (en) | 2020-11-26 | 2020-11-26 | A intelligent drying cabinet for preparing reorganization fibronectin freeze-dried powder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022789640.9U CN213955778U (en) | 2020-11-26 | 2020-11-26 | A intelligent drying cabinet for preparing reorganization fibronectin freeze-dried powder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213955778U true CN213955778U (en) | 2021-08-13 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113866364A (en) * | 2021-10-10 | 2021-12-31 | 威世药业（如皋）有限公司 | Seed of poison freeze-dried powder experimental apparatus |
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