CN213924849U - Special water bath of cell pharmaceutical preparation bag of clinical use - Google Patents

Abstract

The utility model discloses a special water bath for clinically used cell drug preparation bags, which belongs to the technical field of cell drug preparations, and comprises a heat preservation shell, a water bath water tank matched with the heat preservation shell is arranged inside the heat preservation shell, a heating device is arranged inside the water bath water tank, a water bath pot body is also arranged on the upper side of the heat preservation shell, the heat preservation shell is hinged with one end of the water bath pot body, a plurality of shelves are arranged on the inner wall of the heat preservation shell and positioned on the upper side of the water bath water tank, an aluminum top cover is supported on the shelves, a rectangular gap for stably placing preparation bags with different dosages is arranged on the aluminum top cover, compared with the existing water bath pot, the utility model solves the problem that the bacterial contamination rate outside the preparation bags is reduced to the lowest as much as possible when the water bath is clinically used for recovering frozen preparations in the future, so as to prevent accidents which cause serious injury to patients when the infectious agents are clinically used.

Description

Special water bath of cell pharmaceutical preparation bag of clinical use

Technical Field

The utility model relates to a cell pharmaceutical preparation technical field, more specifically say, relate to a special water bath of cell pharmaceutical preparation bag of clinical use.

Background

MSCs (mesenchymalstemcells, MSCs) are a class of primitive undifferentiated cells with multipotentiality and self-replicating ability, have the ability to differentiate into various types of cells, and can differentiate into various cells such as nerve, heart, liver, bone, cartilage, tendon, fat, epithelium, and the like. The rapid development of umbilical cord mesenchymal stem cell therapy technology is expected to fundamentally solve the above problems. Stem cell drugs are receiving great attention from all humans as a new generation of therapeutic drugs under the emerging industrial revolution. The worldwide market size is expected to break through $ 2000 billion by 2024. At present, 14 stem cell medicines or therapies which are approved to be on the market globally mainly take the U.S., korea and europe, and the indications are mainly knee joint cartilage defect, acute myocardial infarction, sugar ulcerative colitis, graft-versus-host disease and the like.

By 5 months in 2019, 7 new stem cell medicines are officially accepted by CFDA in China, wherein 3 new stem cell medicines IND are approved by clinical implication. The injection is prepared from placenta mesenchymal stem cell gel (indication: diabetes foot ulcer) of Beijing Han's combined biotechnology limited company, CBM-ALAM human-derived adipose-derived mesenchymal progenitor cell injection (indication: osteoarthritis) of Wuxi Saiman biotechnology limited company and Xibiman biotechnology (Shanghai) limited company, and umbilical cord mesenchymal stem cell injection (indication: knee osteoarthritis) of Shanghai Isaier biotechnology limited company.

At present, in the clinical use process of domestic cell medicines, cell preparations refrigerated and transported from laboratories or manufacturers are mostly used. In the cell medicine, various cells such as stem cells and immune cells are used, and because the problems of activity of the cells, quality of the preparation, safety and the like are considered, strict timeliness is required to be followed from cell culture preparation to delivery to relevant medical institutions for patients, so that the cells are mostly used in the same day, and the cells are prepared in the same day and belong to fresh cell preparations. However, in the state of the fresh cell preparation, the time span from cell recovery to clinical use is not long, otherwise, the cell activity is lost, thereby affecting the effect of clinical treatment, so that the use of the fresh cell preparation in a remote medical institution is greatly limited by factors such as regions and the like. Therefore, if the cellular drug is eventually brought to the clinic on a large scale, the above problems must be overcome. In summary, most of the new stem cell drugs submitted for CFDA at present are frozen preparations as basic conditions, are convenient to store and are beneficial to large-scale preparation. The frozen formulation has the advantage of avoiding the problems of time-efficiency and the like which must be strictly observed in normal temperature formulations,

in the future, in clinical practice, the process of using the cell pharmaceutical preparation is to deliver the frozen preparation to a medical institution in a refrigeration form from a production enterprise, and after receiving the preparation, clinical medical care personnel heat the preparation by relevant people so as to resuscitate cells in the preparation, and then use the resuscitated cells for patients.

A key step in the process of recovering the frozen preparation and the like is to recover the cells by using a water bath kettle. The water bath is heating equipment which is used in a large amount in medical institutions and experimental institutions at present, but the water bath can only be applied to conventional operation at present. Because the cell medicine belongs to a new medicine at the front, the large-scale clinical use experience is not enough, and the problems of using a large amount of cell preparations and the like are not considered at present. When in clinical resuscitation, only a common water bath kettle can be adopted for resuscitation operation. Many problems are encountered when the ordinary water bath is used for cell recovery. The common water bath is frequently operated and exposed in the air, and although a plurality of preventive measures are taken, the water body in the water tank is often seriously polluted. Before clinical use, before the cell preparation bag is heated, the outside of the preparation bag can be seriously polluted, and the safety of the cell preparation bag in later clinical use is influenced. Because the recipient is the patient, the secondary contamination problem caused by the resuscitation condition is not allowed to occur, and the cleanness of the water bath kettle body is ensured. The preparation used by clinical specialties is used for reviving the desire of the water bath kettle.

SUMMERY OF THE UTILITY MODEL

1. Technical problem to be solved

To the problem that exists among the prior art, the utility model aims to provide a special water bath of cell pharmaceutical preparation bag of clinical use, compare with current water bath, the utility model provides a will be prepared when water bath resuscitation freezes the preparation clinically in the future, will prepare the contamination rate in the bag outside and fall to minimum as far as to prevent to take place to cause the accident of major injury to the patient when clinical use contamination preparation.

2. Technical scheme

In order to solve the above problems, the utility model adopts the following technical proposal.

The utility model provides a special water bath of cell pharmaceutical preparation bag of clinical use, includes the lagging casing, the inside water bath basin that is equipped with and lagging casing assorted of lagging casing, the inside heating device that is equipped with in water bath basin, the upside of lagging casing still is equipped with the water bath pot body, the lagging casing is connected with the one end of the water bath pot body is articulated, the upside that lies in the water bath basin on the inner wall of lagging casing is equipped with a plurality of shelves, and is a plurality of it has the aluminium top cap to support on the shelf, be equipped with the rectangle gap that is used for stably putting different dosage preparation bags on the aluminium top cap. When using the water bath, place the cell preparation bag in the rectangle gap on aluminium system top cap after opening the water bath pot body, close the water bath pot body after opening heating device, can carry out water bath heating to the cell preparation bag, compare with current water bath, the utility model provides a future when using water bath pot recovery freezing preparation clinically, will prepare the contamination rate in the bag outside and fall to minimum as far as to prevent to take place to cause the accident of major injury to the patient when clinical use contamination preparation.

The aluminium system top cap includes the aluminium plate body, the circular through-hole in a plurality of different apertures has been seted up on the aluminium plate body, still support in the circular through-hole with circular through-hole assorted circular apron, all seted up a rectangle through-hole on every circular apron, and a plurality of rectangle through-holes's all inequality. Set up the circular through-hole in a plurality of different apertures and take off circular household utensils such as beaker or test tube can be placed with circular apron, and the rectangular through-hole of a plurality of sizes differences that set up simultaneously can conveniently place the cell preparation bag, and the rectangular through-hole of square structure can effectively stabilize the cell preparation bag.

A closed protective cover is fixed on the inner wall of the water bath kettle body, an ultraviolet lamp is arranged inside the closed protective cover, and water and a water bath kettle inner container operation area can be disinfected at regular time according to actual use frequency of the water bath kettle or a user according to needs.

Be equipped with control panel on the front side outer wall of lagging casing, control panel is last to install the ultraviolet lamp switch that is used for switching on and off ultraviolet lamp, is used for switching on and off heating device's LED to show frequently and be used for showing the heating switch of heating temperature, conveniently controls the water-bath.

The connection part of the heat preservation shell and the water bath kettle body is also provided with a locking buckle for quickly opening and closing the water bath kettle body, so that the water bath kettle is convenient for a user to use.

3. Advantageous effects

Compared with the prior art, the utility model has the advantages of:

compare with current water bath, the utility model provides a future use water bath recovery when freezing preparation clinically, will prepare the contamination rate in the bag outside and reduce to minimum as far as possible to prevent to take place to cause the accident of serious injury to the patient when clinical use contamination preparation.

Drawings

Fig. 1 is a front view of the present invention;

FIG. 2 is a schematic view of the internal structure of the present invention;

fig. 3 is a top view of the middle shelf of the present invention.

The reference numbers in the figures illustrate:

1 heat preservation shell, 2 water bath pot body, 3 water bath water tank, 4 shelves, 5 aluminium top covers, 501 aluminium plate body, 502 circular through hole, 503 circular cover plate, 504 rectangular through hole, 6 ultraviolet lamp, 7 ultraviolet lamp switch, 8 LED display frequency, 9 heating switch, 10 heating device.

Detailed Description

The drawings in the embodiments of the present invention will be combined; the technical scheme in the embodiment of the utility model is clearly and completely described; obviously; the described embodiments are only some of the embodiments of the present invention; but not all embodiments, are based on the embodiments of the invention; all other embodiments obtained by a person skilled in the art without making any inventive step; all belong to the protection scope of the utility model.

In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted", "provided", "sleeved/connected", "connected", and the like are to be understood in a broad sense, such as "connected", which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

Example 1:

referring to fig. 1-2, a water bath kettle special for a clinically used cell drug preparation bag, the whole water bath kettle is formed by folding and welding imported high-quality 304 stainless steel and comprises a heat insulation shell 1, a water bath kettle water tank 3 matched with the heat insulation shell 1 is arranged inside the heat insulation shell 1, a heating device 10 is arranged inside the water bath kettle water tank 3, a water bath kettle body 2 is further arranged on the upper side of the heat insulation shell 1, the heat insulation shell 1 is hinged with one end of the water bath kettle body 2, a plurality of shelves 4 are arranged on the inner wall of the heat insulation shell 1 and located on the upper side of the water bath kettle water tank 3, an aluminum top cover 5 is supported on the shelves 4, and rectangular gaps for stably placing preparation bags with different dosages are formed in the aluminum top cover 5. When using the water bath, place the cell preparation bag in the rectangle gap on aluminium system top cap 5 after opening water bath pot body 2, close and open heating device behind the water bath pot body 2, can carry out water bath heating to the cell preparation bag, compare with current water bath, the utility model provides a future when using water bath pot recovery freezing preparation clinically, will prepare the contamination rate in the bag outside and fall to minimum as far as to prevent to take place to cause the accident of serious injury to the patient when clinical use contamination preparation.

Referring to fig. 2-3, the aluminum top cover 5 includes an aluminum plate 501, a plurality of circular through holes 502 with different apertures are formed on the aluminum plate 501, circular cover plates 503 matching with the circular through holes 502 are supported in the circular through holes 502, each circular cover plate 503 is formed with a rectangular through hole 504, and the sizes of the rectangular through holes 504 are different. Set up the circular through-hole 502 in a plurality of different apertures and take off circular apron 503 and can place circular household utensils such as beaker or test tube, the rectangle through-hole 504 that a plurality of sizes that set up simultaneously are different can conveniently place the cell preparation bag, and the rectangle through-hole 504 of square structure can effectively stabilize the cell preparation bag.

Referring to fig. 1-2, a closed protective cover is fixed on the inner wall of the water bath kettle body 2, and an ultraviolet lamp 6 is installed inside the closed protective cover, so that the water body and the water bath kettle liner operating area can be disinfected at regular time according to the actual using frequency of the water bath kettle or the requirement of a user.

Referring to fig. 1, a control panel is disposed on the outer wall of the front side of the heat-insulating housing 1, and an ultraviolet lamp switch 7 for switching an ultraviolet lamp 6, an LED display frequency 8 for switching a heating device, and a heating switch 9 for displaying a heating temperature are mounted on the control panel, so that the water bath can be conveniently controlled.

Referring to fig. 1-2, a locking buckle is further disposed at a joint between the thermal insulation housing 1 and the water bath kettle body 2 for rapidly opening and closing the water bath kettle body 2, so as to facilitate use by a user.

The above; is only a preferred embodiment of the present invention; however, the scope of protection of the present invention is not limited thereto; any person skilled in the art is within the technical scope of the present disclosure; according to the technical scheme of the utility model and the improvement conception, equivalent substitution or change is carried out; are all covered by the protection scope of the utility model.

Claims (5)

1. A special water bath of cell pharmaceutical preparation bag of clinical use, includes heat preservation shell (1), its characterized in that: the utility model discloses a water bath kettle, including heat preservation shell (1), heat preservation shell (1) inside be equipped with heat preservation shell (1) assorted water bath basin (3), water bath basin (3) inside is equipped with heating device (10), the upside of heat preservation shell (1) still is equipped with the water bath kettle body (2), heat preservation shell (1) is connected with the one end of the water bath kettle body (2) is articulated, the upside that lies in water bath kettle basin (3) on the inner wall of heat preservation shell (1) is equipped with a plurality of shelves (4), and is a plurality of it has aluminium top cap (5) to support on shelf (4), be equipped with the rectangle gap that is used for stably putting different dosage preparation bags on aluminium top cap (5).

2. The special water bath kettle for the cell medicine preparation bag for clinical use according to claim 1, wherein: aluminium system top cap (5) include aluminum plate body (501), set up circular through-hole (502) in a plurality of different apertures on aluminum plate body (501), still support in circular through-hole (502) with circular through-hole (502) assorted circular apron (503), all seted up one rectangle through-hole (504) on every circular apron (503), and the size inequality of a plurality of rectangle through-holes (504).

3. The special water bath kettle for the cell medicine preparation bag for clinical use according to claim 1, wherein: a closed protective cover is fixed on the inner wall of the water bath kettle body (2), and an ultraviolet lamp (6) is installed inside the closed protective cover.

4. The special water bath kettle for the cell medicine preparation bag for clinical use according to claim 1, wherein: the heat preservation shell is characterized in that a control panel is arranged on the outer wall of the front side of the heat preservation shell (1), and an ultraviolet lamp switch (7) used for switching on and off an ultraviolet lamp (6), an LED display frequency (8) used for switching on and off a heating device and a heating switch (9) used for displaying heating temperature are mounted on the control panel.

5. The special water bath kettle for the cell medicine preparation bag for clinical use according to claim 1, wherein: the joint of the heat preservation shell (1) and the water bath kettle body (2) is also provided with a locking buckle.

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