CN213911394U

CN213911394U - Wet granulation system

Info

Publication number: CN213911394U
Application number: CN202021747467.XU
Authority: CN
Inventors: 杨超; 彭昊; 毛丹; 石义刚
Original assignee: Grand Pharma China Co ltd
Current assignee: Grand Pharma China Co ltd
Priority date: 2020-08-19
Filing date: 2020-08-19
Publication date: 2021-08-10
Anticipated expiration: 2030-08-19

Abstract

The utility model provides a wet granulation system, wet granulation system includes: the wet granulator is internally provided with a granulating knife and a stirring paddle; the gas supply equipment is connected with a first branch pipeline, and the first branch pipeline is respectively connected with the granulating knife and the stirring paddle; wherein, from air feeder to pelletization sword or stirring rake direction, first solenoid valve and first pressure detector have set gradually on the first branch pipeline. The utility model discloses a wet granulation system is through installing solenoid valve and the pressure detector of survey pelletization sword and stirring rake department additional to accurately judge the air pressure of supplying in pelletization sword and stirring rake, thereby improve and establish because of the inaccurate dust wearing and tearing that lead to of the airtight atmospheric pressure detection of axle, perhaps the dust accumulation leads to the material to be polluted the scheduling problem, improve equipment life, improve product quality.

Description

Wet granulation system

Technical Field

The utility model relates to a medicine field. Specifically, the utility model relates to a wet granulation equipment.

Background

In the pharmaceutical industry, solid pharmaceutical preparations such as tablets, capsules, granules and the like are the most widely used forms of pharmaceutical preparations. The most important step in the manufacturing process of these pharmaceutical dosage forms is granulation, and the apparatus commonly used for granulation is a granulator. When the granulator works, the stirring paddle and the two rotating shafts of the granulating cutter are protected by air sealing, namely compressed air coming out from an air source is blown to the stirring paddle and the granulating cutter, so that the influence of dust deposition on the product quality and the abrasion of equipment caused by the dust deposition at the rotating shafts are prevented. The compressed air from the air source is detected by the electromagnetic valve and the pressure detector to judge whether the pressure of the compressed air reaches the standard or not, so that the requirement of air sealing is met, and the pressure detector detects the total pressure value. However, the compressed air from the air source is not only supplied to the stirring paddle and the granulating cutter, but also shunted to other equipment, such as a slurry adding tank, the pressure is attenuated through shunting and pipelines, and the total pressure value detected here cannot accurately reflect the air pressure of the shaft air seal, so that the effect of the shaft air seal cannot be ensured.

Thus, the wet granulation system is still to be improved.

SUMMERY OF THE UTILITY MODEL

The present invention aims at solving at least one of the technical problems existing in the prior art to at least a certain extent. Therefore, the utility model provides a wet granulation system is through installing solenoid valve and the pressure detector of survey pelletization sword and stirring rake department additional to accurately judge the air pressure of supplying in pelletization sword and stirring rake, thereby improve because of the inaccurate dust wearing and tearing equipment or the contaminated material scheduling problem that leads to of the airtight atmospheric pressure detection of axle, improve equipment life, improve product quality.

The utility model provides a wet granulation system, wet granulation system includes: the wet granulator is internally provided with a granulating knife and a stirring paddle; the gas supply equipment is connected with a first branch pipeline, and the first branch pipeline is respectively connected with the granulating knife and the stirring paddle; wherein, from air feeder to pelletization sword or stirring rake direction, first solenoid valve and first pressure detector have set gradually on the first branch pipeline.

The utility model discloses an among the wet granulation system, set up first solenoid valve and first pressure detector on the first branch pipeline of connecting pelletization sword and stirring rake, can accurately judge the air pressure of supplying in pelletization sword and stirring rake to the improvement is established because of the inaccurate dust wearing and tearing that lead to of the airtight atmospheric pressure detection of axle, and perhaps the dust accumulation leads to the material to be polluted the scheduling problem, improve equipment life, improvement product quality.

Specifically, a first pressure regulating valve is arranged on the first branch pipeline.

Specifically, the gas supply equipment is connected with at least one second branch pipeline, and the second branch pipeline is connected with the slurry adding tank.

Specifically, each second branch pipeline is sequentially provided with a second electromagnetic valve, a second pressure detector and a second pressure regulating valve from the air supply device to the direction of the slurry adding tank.

Specifically, a main pipeline is connected to the gas supply equipment, and the first branch pipeline and each of the second branch pipelines are respectively connected with the main pipeline; and a main pressure regulating valve is arranged on the main pipeline.

Specifically, the wet granulation system further comprises: the computing equipment is respectively connected with the first pressure detector and the second pressure detector; and the control equipment is respectively connected with the main pressure regulating valve, the first electromagnetic valve, the first pressure detector, the first pressure regulating valve, the second electromagnetic valve, the second pressure detector, the second pressure regulating valve and the calculating equipment.

Specifically, the first pressure detector and the second pressure detector are respectively connected with an alarm device.

Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.

Drawings

The above and/or additional aspects and advantages of the present invention will become apparent and readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings of which:

fig. 1 shows a schematic structural diagram of a wet granulation system according to an embodiment of the present invention.

Detailed Description

Embodiments of the present invention are described in detail below. The following description of the embodiments is merely exemplary in nature and is in no way intended to limit the invention.

In the present invention, unless otherwise expressly stated or limited, the terms "connected" and "connected" are to be construed broadly, e.g., as meaning a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.

The utility model provides a wet granulation system. According to an embodiment of the present invention, referring to fig. 1, the wet granulation system comprises: a wet granulator 100, wherein a granulating knife 110 and a stirring paddle 120 are arranged in the wet granulator 100; the gas supply device 200 is connected with a first branch pipeline 210, and the first branch pipeline 210 is respectively connected with the granulating knife 110 and the stirring paddle 120; wherein, a first electromagnetic valve 211 and a first pressure detector 212 are sequentially disposed on the first branch pipeline 210 from the gas supply device 200 to the granulating blade 110 or the stirring paddle 120.

When the wet granulator works, the air supply device is started to provide compressed air to the granulating knife and the stirring paddle to blow away dust, so that the dust is prevented from being deposited on the rotating shaft to cause equipment abrasion or material pollution. The first solenoid valve is closed, and the first pressure detector may detect the air pressure on the first branch line. If the air pressure is lower than the threshold value, the air pressure reaching the granulating cutter and the stirring paddle is not up to the standard, and the air supply pressure of each part or pipeline or the air supply equipment needs to be checked. If the air pressure is not lower than the threshold value, the air pressure reaching the granulating cutter and the stirring paddle is judged to reach the standard. Therefore, the problems that the equipment is abraded by dust or materials are polluted due to inaccurate detection of the air pressure of the shaft air seal can be solved, the service life of the equipment is prolonged, and the product quality is improved.

According to an embodiment of the present invention, the first branch pipeline 210 is provided with a first pressure regulating valve 213. The air pressure on the first branch pipeline is controlled by adjusting the first pressure regulating valve. If the air pressure detected by the first pressure detector is lower than the threshold value, the air pressure on the first branch pipeline can be increased through the first pressure regulating valve, and if the first pressure regulating valve is opened to the maximum, the air supply pressure of each part or pipeline or the air supply equipment needs to be checked or increased. If the air pressure detected by the first pressure detector is not lower than the threshold value, the air pressure reaching the granulating cutter and the stirring paddle is indicated to reach the standard, and if the air pressure is too high, the first pressure regulating valve can be adjusted to reduce the air pressure on the first branch pipeline, so that the phenomenon of overlarge dust raising in the granulating machine is avoided.

According to the utility model discloses an embodiment is connected with at least one second branch pipeline 220 on the gas supply equipment 200, and second branch pipeline 220 links to each other with adding thick liquid jar 130. Thus, the air supply device can supply air for the slurry adding tank. According to the utility model discloses an embodiment, from air supply equipment 200 to adding thick liquid jar 130 direction, set gradually second solenoid valve 221, second pressure detector 222 and second air-vent valve 223 on every second branch pipeline 220. Therefore, the air pressure on the second branch pipeline can be detected by the second electromagnetic valve and the second pressure detector, and the air pressure on the pipeline is regulated by the second pressure regulating valve according to actual needs.

According to the embodiment of the present invention, the main pipeline 310 is connected to the gas supply device 200, and the first branch pipeline 210 and each of the second branch pipelines 220 are respectively connected to the main pipeline 310; the main line is provided with a main pressure regulating valve 311. The air pressure in each branch line can be controlled by the main pressure regulating valve. Specifically, if the first pressure detector and the second pressure detector detect that the air pressure on the first branch pipeline and the air pressure on the second branch pipeline are respectively higher, the air pressure on the main pipeline can be reduced by adjusting the main pressure regulating valve, and then the pressure shunted to each branch pipeline is correspondingly reduced, so that the first pressure regulating valve and the second pressure regulating valve do not need to be adjusted independently. Similarly, if the air pressure in each of the branch lines is low, the air pressure in the main line can be increased by adjusting the main pressure regulating valve, and the pressure branched to each of the branch lines is increased accordingly.

According to the utility model discloses an embodiment, wet granulation system further includes: the computing equipment is respectively connected with the first pressure detector and the second pressure detector; and the control equipment is respectively connected with the main pressure regulating valve, the first electromagnetic valve, the first pressure detector, the first pressure regulating valve, the second electromagnetic valve, the second pressure detector, the second pressure regulating valve and the calculating equipment. Thus, the control device regulates the closing of the first electromagnetic valve and the closing of the second electromagnetic valve, and the opening of the first pressure detector and the second pressure detector so as to respectively detect the air pressure on the first branch pipeline and the second branch pipeline. And feeding back the air pressures measured by the first pressure detector and the second pressure detector to the computing equipment, comparing the relation between the air pressure value and the threshold value, and feeding back the result to the control equipment to control the first pressure regulating valve, the second pressure regulating valve and the main pressure regulating valve to maintain the original state or increase or decrease.

According to the utility model discloses an embodiment is connected with alarm device on first pressure detector and the second pressure detector respectively. Therefore, when the first pressure detector and the second pressure detector detect that the air pressure on the branch pipeline is not qualified, the alarm device can be started, so that the first pressure regulating valve, the second pressure regulating valve and the main pressure regulating valve can be conveniently adjusted subsequently or whether all the parts and the pipelines are normal or not can be conveniently checked.

In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.

Although embodiments of the present invention have been shown and described, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention, and that variations, modifications, substitutions and alterations can be made to the above embodiments by those of ordinary skill in the art without departing from the scope of the present invention.

Claims

1. A wet granulation system, comprising:

the wet granulator is internally provided with a granulating knife and a stirring paddle;

the gas supply equipment is connected with a first branch pipeline, and the first branch pipeline is respectively connected with the granulating knife and the stirring paddle;

wherein, from air feeder to pelletization sword or stirring rake direction, first solenoid valve and first pressure detector have set gradually on the first branch pipeline.

2. The wet granulation system of claim 1, wherein a first pressure regulating valve is disposed on the first branch line.

3. The wet granulation system of claim 2, wherein at least one second branch line is connected to the gas supply apparatus, and the second branch line is connected to the slurry tank.

4. The wet granulation system as claimed in claim 3, wherein a second solenoid valve, a second pressure detector and a second pressure regulating valve are sequentially disposed on each of the second branch pipes from the gas supply device to the slurry tank.

5. The wet granulation system as claimed in claim 4, wherein a main pipeline is connected to the gas supply device, and the first branch pipeline and each of the second branch pipelines are respectively connected to the main pipeline;

and a main pressure regulating valve is arranged on the main pipeline.

6. The wet granulation system of claim 5, further comprising:

the computing equipment is respectively connected with the first pressure detector and the second pressure detector;

and the control equipment is respectively connected with the main pressure regulating valve, the first electromagnetic valve, the first pressure detector, the first pressure regulating valve, the second electromagnetic valve, the second pressure detector, the second pressure regulating valve and the calculating equipment.

7. The wet granulation system of claim 4, wherein an alarm device is connected to each of the first pressure detector and the second pressure detector.