CN213835125U - Protein dialysis device - Google Patents
Protein dialysis device Download PDFInfo
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- CN213835125U CN213835125U CN202021764278.3U CN202021764278U CN213835125U CN 213835125 U CN213835125 U CN 213835125U CN 202021764278 U CN202021764278 U CN 202021764278U CN 213835125 U CN213835125 U CN 213835125U
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- dialysis
- negative pressure
- fixedly connected
- dialysis bag
- bag
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- 238000000502 dialysis Methods 0.000 title claims abstract description 192
- 102000004169 proteins and genes Human genes 0.000 title claims abstract description 21
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 21
- 244000309464 bull Species 0.000 claims description 9
- 238000005119 centrifugation Methods 0.000 claims description 7
- 238000009795 derivation Methods 0.000 claims description 2
- 230000006698 induction Effects 0.000 claims description 2
- 238000009434 installation Methods 0.000 abstract description 11
- 238000010030 laminating Methods 0.000 abstract description 9
- 238000002474 experimental method Methods 0.000 abstract description 2
- 238000000034 method Methods 0.000 abstract description 2
- 238000011982 device technology Methods 0.000 abstract 1
- 238000013461 design Methods 0.000 description 8
- 239000007788 liquid Substances 0.000 description 4
- 239000007853 buffer solution Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000000385 dialysis solution Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000001742 protein purification Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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Abstract
The utility model discloses a protein dialysis device, which comprises a dialysis device main body, a dialysis integrated negative pressure device and a dialysis beaker, wherein the top of the dialysis device main body is embedded and connected with the dialysis integrated negative pressure device, the bottom of the dialysis device main body is fixedly connected with the dialysis beaker, the bottom end of the dialysis integrated negative pressure device is movably connected with a hollow centrifugal rotating rod, one end of the hollow centrifugal rotating rod is fixedly connected with a dialysis bag fixing device, two sides of the interior of the dialysis device main body are movably connected with a device fixing occlusion clamp, the device fixing occlusion clamp lightens the operation burden of an operator, the anti-shake laminating chassis well slows down the influence caused by vibration, a portable holding groove is well convenient for the operator to carry out handheld operation, the dialysis integrated negative pressure device well embodies the operation convenience of the device, the dialysis bag fixing device well embodies the practicability and the installation convenience of the device, the method is suitable for the use of the biological experiment device technology, and has wide development prospect in the future.
Description
Technical Field
The utility model relates to the technical field of biological experiment devices, in particular to a protein dialysis device.
Background
Most of protein dialysis is to put a dialysis bag into dialysis buffer solution, and then to drive a magnetic rotor to rotate by adopting a magnetic stirrer so as to enable the dialysis buffer solution to form vortex, thereby promoting the permeation of micromolecular protein or other impurities in the dialysis bag, reserving target macromolecular protein and achieving the purpose of protein purification.
The existing device is troublesome when a dialysis bag is fixed in installation, the installation convenience is not enough, and when a plurality of dialysis bags are dialyzed simultaneously, the dialysis solution is easily entangled, the dialysis solution needs to be repeatedly opened and replaced when the dialysis device is operated, the operation convenience is not enough, and meanwhile, due to the fact that the dialysis device can generate certain vibration when the dialysis device is operated, an operator is not convenient to control, and the device is not provided with a good shockproof design.
Therefore, how to design a protein dialysis device becomes a problem that we need to solve at present.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a protein dialysis device to solve the not enough problem of installation convenience and the not enough of simple operation nature that proposes in the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme: a protein dialysis device comprises a dialysis device main body, a dialysis integrated negative pressure device and a dialysis beaker, wherein the top of the dialysis device main body is connected with the dialysis integrated negative pressure device in an embedded manner, the bottom of the dialysis device main body is fixedly connected with the dialysis beaker, the bottom end of the dialysis integrated negative pressure device is movably connected with a hollow centrifugal rotating rod, one end of the hollow centrifugal rotating rod is fixedly connected with a dialysis bag fixing device, one side of the inner top of the hollow centrifugal rotating rod is connected with a lead-in pipe in an embedded manner, the other side of the inner top of the hollow centrifugal rotating rod is connected with a lead-out pipe in an embedded manner, the middle part of the inner part of the dialysis integrated negative pressure device is fixedly connected with a centrifugal dialysis motor, one side of the inner part of the dialysis integrated negative pressure device is fixedly connected with a lead-in containing groove, and the other side of the inner part of the dialysis integrated negative pressure device is fixedly connected with a negative pressure lead-out containing groove, dialysis bag fixing device's inside one side swing joint has the dialysis bag to sticis the card bolt, dialysis bag fixing device's inside opposite side swing joint has the dialysis bag to sticis the side bolt, dialysis bag fixing device's inside middle part fixedly connected with dialysis bag runs through the mouth, the inside inboard through connection that the dialysis bag ran through the mouth has the dialysis bag sack, the bottom fixedly connected with dialysis bag of dialysis bag sack.
Preferably, a portable holding groove is fixedly connected to one side of the dialysis beaker.
Preferably, the bottom end of the dialysis beaker is fixedly connected with an anti-shake fit chassis.
Preferably, the two sides in the dialysis device main body are movably connected with device fixing occlusion clips.
Preferably, the integrative negative pressure device of dialysis is by the cavity centrifugation bull stick of bottom, the induction pipe of the inside top one side of cavity centrifugation bull stick, the delivery pipe of the inside top opposite side of cavity centrifugation bull stick, the centrifugal dialysis motor of inside middle part, the leading-in appearance groove of inside one side and the negative pressure of inside opposite side are derived and are held the groove and make up jointly and form.
Preferably, dialysis bag fixing device is by the dialysis bag of inside one side sticis the card bolt, and the dialysis bag of inside opposite side sticiss the side bolt, and the dialysis bag of inside middle part runs through the mouth, and the dialysis bag of the inside inboard dialysis bag sack of dialysis bag run through mouth and the dialysis bag of dialysis bag sack bottom make up jointly and form.
Compared with the prior art, the beneficial effects of the utility model are that:
1. the protein dialysis device is provided with the dialysis integrated negative pressure device, the dialysis integrated negative pressure device drives the hollow centrifugal rotating rod to carry out centrifugal dialysis through the centrifugal dialysis motor, the hollow centrifugal rotating rod is in a hollow design, when liquid needs to be changed, the changed old liquid is led out to the leading-out containing groove along the leading-out pipe through negative pressure suction, after the leading-out is completed, the new dialysate can be changed conveniently and quickly by leading in the leading-in containing groove along the leading-in pipe without being opened repeatedly, and the operation convenience of the device is well reflected;
2. this protein dialysis device, during the installation, pull open the gim peg of device both sides to both sides, penetrate the dialysis bag sack of dialysis bag along the dialysis bag of device through the mouth, penetrate the completion back, sticis the gim peg with the dialysis bag of both sides and sticiss the side bolt and loosen and carry out the chucking fastening to the dialysis bag sack, alright completion is fixed to the installation of dialysis bag, convenient and fast, and the three group's devices that set up from top to bottom, set up in order from a left side to the right side, mutual noninterference, the fine practicality and the installation convenience that has embodied the device.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic sectional view of the main body of the dialysis device of the present invention;
fig. 3 is an enlarged schematic view of the utility model at a;
fig. 4 is an enlarged schematic view of the position B of the present invention.
In the figure: 1. the dialysis device main part, 2, the integrative negative pressure device of dialysis, 3, the dialysis beaker, 4, portable groove of holding, 5, anti-shake laminating chassis, 6, cavity centrifugation bull stick, 7, dialysis bag fixing device, 701, dialysis bag sticiss the gim peg, 702, dialysis bag sticiss the side tie, 703, dialysis bag run-through mouth, 704, dialysis bag sack, 705, dialysis bag, 8, the induction-in pipe, 9, the delivery tube, 10, centrifugal dialysis motor, 11, leading-in appearance groove, 12, the appearance groove is derived to the negative pressure, 13, the fixed interlock of device presss from both sides.
Detailed Description
The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, rather than all embodiments, and all other embodiments obtained by a person of ordinary skill in the art without creative work belong to the protection scope of the present invention based on the embodiments of the present invention.
Referring to fig. 1-4, the present invention provides a technical solution: a protein dialysis device comprises a dialysis device main body 1, a dialysis integrated negative pressure device 2 and a dialysis beaker 3, wherein the top of the dialysis device main body 1 is embedded and connected with the dialysis integrated negative pressure device 2, the bottom of the dialysis device main body 1 is fixedly connected with the dialysis beaker 3, the bottom end of the dialysis integrated negative pressure device 2 is movably connected with a hollow centrifugal rotating rod 6, one end of the hollow centrifugal rotating rod 6 is fixedly connected with a dialysis bag fixing device 7, one side of the inner top of the hollow centrifugal rotating rod 6 is embedded and connected with a leading-in pipe 8, the other side of the inner top of the hollow centrifugal rotating rod 6 is embedded and connected with a leading-out pipe 9, the middle part of the inner part of the dialysis integrated negative pressure device 2 is fixedly connected with a centrifugal dialysis motor 10, one side of the inner part of the dialysis integrated negative pressure device 2 is fixedly connected with a leading-in containing groove 11, and the other side of the inner part of the dialysis integrated negative pressure device 2 is fixedly connected with a negative pressure leading-out containing groove 12, dialysis bag fixing device 7's inside one side swing joint has the dialysis bag to sticis card bolt 701, and dialysis bag fixing device 7's inside opposite side swing joint has the dialysis bag to sticis side bolt 702, and dialysis bag fixing device 7's inside middle part fixedly connected with dialysis bag runs through mouth 703, and the inside inboard through connection of dialysis bag running through mouth 703 has dialysis bag sack 704, and the bottom fixedly connected with dialysis bag 705 of dialysis bag sack 704.
Preferably, one side fixedly connected with of dialysis beaker 3 holds groove 4 portably, and the dialysis device is when moving, and operating personnel need hold the beaker and carry out the auxiliary operation, and current beaker outer wall is many comparatively smooth, and the slippage takes place easily when operating personnel is handheld to operate, holds groove 4 through setting up portably, and the groove 4 is held for portably holding, and the design of fine indent is held to the portably, laminating people's palm that can be fine, fine having made things convenient for operating personnel to carry out handheld operation.
Preferably, dialysis beaker 3's bottom fixedly connected with anti-shake laminating chassis 5 because dialysis device can produce certain vibrations when the operation, and the operating personnel of being not convenient for controls, through setting up anti-shake laminating chassis 5, anti-shake laminating chassis 5 is sucking disc formula chassis, can be fine adsorb in the underlying surface, and ground intensity is grabbed in effectual increase, fine slowing down the influence that vibrations caused.
Preferably, the inside both sides swing joint of dialysis unit main part 1 has device fixed interlock to press from both sides 13, and current dialysis unit needs operating personnel to assist and operates on the beaker, and unable convenient fixing is on the beaker by oneself, through setting up device fixed interlock clamp 13, device fixed interlock clamp 13 is the spring clamp design of mobile regulation, and both sides set up one respectively, and adjustable back centre gripping is in the both sides of beaker to need not operating personnel auxiliary operation, fine reduction operating personnel's operation burden.
Preferably, the dialysis integrated negative pressure device 2 is formed by combining a hollow centrifugal rotating rod 6 at the bottom end, a leading-in pipe 8 at one side of the top inside the hollow centrifugal rotating rod 6, a leading-out pipe 9 at the other side of the top inside the hollow centrifugal rotating rod 6, a centrifugal dialysis motor 10 at the middle part inside, a leading-in containing groove 11 at one side of the inside and a negative pressure leading-out containing groove 12 at the other side of the inside together, the existing protein dialysis device needs to be repeatedly opened to replace dialysate during operation, which is troublesome, the dialysis integrated negative pressure device 2 is arranged, the dialysis integrated negative pressure device 2 drives the hollow centrifugal rotating rod 6 to carry out centrifugal dialysis through the centrifugal dialysis motor 10, the hollow centrifugal rotating rod 6 is of a hollow design, when the dialysate needs to be replaced, the replaced old dialysate is led out to the leading-out containing groove 12 through the leading-in containing groove 11 through the negative pressure, and the new dialysate can be led in along the leading-in pipe 8 through the leading-in containing groove, convenient and fast need not to open repeatedly, fine embodiment the device's simple operation nature. Preferably, the dialysis bag fixing device 7 is formed by combining a dialysis bag pressing clamping bolt 701 on one side inside, a dialysis bag pressing side bolt 702 on the other side inside, a dialysis bag through hole 703 on the middle part inside, a dialysis bag opening 704 on the inner side inside the dialysis bag through hole 703 and a dialysis bag 705 at the bottom end of the dialysis bag opening 704, the existing device is troublesome in mounting and fixing dialysis bags, and a plurality of dialysis bags are dialyzed simultaneously and are easy to be entangled, by arranging the dialysis bag fixing device 7, the clamping bolts on the two sides of the device are pulled open towards the two sides during mounting, then the dialysis bag opening 704 of the dialysis bag 705 is inserted along the dialysis bag through hole 703 of the device, after the insertion is completed, the dialysis bag pressing clamping bolts 701 on the two sides and the dialysis bag pressing side bolt 702 are loosened to clamp and fasten the dialysis bag opening, so that the mounting and fixing of the dialysis bag 705 can be completed, the device is convenient and fast, and the three sets of devices are arranged from top to bottom, the device is orderly arranged from left to right without mutual interference, and the practicability and the installation convenience of the device are well embodied.
The working principle is as follows: firstly, through setting up portablely holding and holding groove 4, portablely hold and hold groove 4 and for fine indent design, laminating people's palm that can be fine has made things convenient for operating personnel to carry out handheld operation.
Then, through setting up anti-shake laminating chassis 5, anti-shake laminating chassis 5 is sucking disc formula chassis, and absorption in the underlying surface that can be fine, effectual increase grabs ground intensity, fine has slowed down the influence that vibrations caused. Then, the process of the present invention is carried out,
by arranging the device fixing occlusion clamp 13, the device fixing occlusion clamp 13 is designed as a spring clamp capable of being movably adjusted, two sides of the device fixing occlusion clamp are respectively provided with one spring clamp, and the device fixing occlusion clamp can be clamped on two sides of the beaker after being adjusted, so that the auxiliary operation of an operator is not needed, and the operation burden of the operator is well lightened;
next, through setting up integrative negative pressure device 2 of dialysis, integrative negative pressure device 2 of dialysis drives hollow centrifugal bull stick 6 through centrifugal dialysis motor 10 and carries out centrifugal dialysis, hollow centrifugal bull stick 6 is the hollow design, when needing to change liquid, through the negative pressure suction with the old liquid of changing out to derive from holding groove 12 along eduction tube 9, after the derivation is accomplished, can accomplish the change through leading-in holding groove 11 along the leading-in pipe 8 with new dislysate, and is convenient and fast, need not to open repeatedly, the good operation convenience who embodies the device;
finally, through setting up dialysis bag fixing device 7, during the installation, pull open the gim peg of device both sides to both sides, penetrate dialysis bag sack 704 with dialysis bag 705 along the dialysis bag of device run-through mouth 703 after penetrating, penetrate the completion back, sticis gim peg 701 and dialysis bag with the dialysis bag of both sides and sticiss side bolt 702 and loosen and carry out the chucking fastening to dialysis bag sack 704, alright completion is fixed to the installation of dialysis bag 705, convenient and fast, and the three group's devices that set up from top to bottom, set up in order from a left side to right side, mutual noninterference, the fine practicality and the installation convenience that have embodied the device, this is exactly this protein dialysis device's theory of operation.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. The utility model provides a protein dialysis device, includes dialysis device main part (1), integrative negative pressure device (2) of dialysis and dialysis beaker (3), its characterized in that: the integrated negative pressure dialysis device is characterized in that a dialysis integrated negative pressure device (2) is connected to the top of a dialysis device main body (1) in an embedded mode, a hollow centrifugal rotating rod (6) is movably connected to the bottom end of the dialysis integrated negative pressure device (2), a dialysis bag fixing device (7) is fixedly connected to one end of the hollow centrifugal rotating rod (6), a lead-in pipe (8) is connected to one side of the inner top of the hollow centrifugal rotating rod (6) in an embedded mode, a lead-out pipe (9) is connected to the other side of the inner top of the hollow centrifugal rotating rod (6) in an embedded mode, a centrifugal dialysis motor (10) is fixedly connected to the middle portion of the inner portion of the dialysis integrated negative pressure device (2), a lead-in containing groove (11) is fixedly connected to one side of the inner portion of the dialysis integrated negative pressure device (2), a negative pressure lead-out containing groove (12) is fixedly connected to the other side of the inner portion of the dialysis bag fixing device (7), and a dialysis bag clamping bolt (701) is movably connected to one side of the inner portion, the inside opposite side swing joint of dialysis bag fixing device (7) has the dialysis bag to sticis side bolt (702), the inside middle part fixedly connected with dialysis bag of dialysis bag fixing device (7) runs through mouth (703), the inside inboard through connection of dialysis bag running through mouth (703) has dialysis bag sack (704), the bottom fixedly connected with dialysis bag (705) of dialysis bag sack (704).
2. A protein dialysis device according to claim 1, wherein: the bottom of the dialysis device main body (1) is fixedly connected with a dialysis beaker (3).
3. A protein dialysis device according to claim 2, wherein: one side of the dialysis beaker (3) is fixedly connected with a portable holding groove (4).
4. A protein dialysis device according to claim 2, wherein: the bottom end of the dialysis beaker (3) is fixedly connected with an anti-shake fit chassis (5).
5. A protein dialysis device according to claim 1, wherein: the dialysis device is characterized in that device fixing occlusion clips (13) are movably connected to two sides of the interior of the dialysis device body (1).
6. A protein dialysis device according to claim 1, wherein: the integrative negative pressure device (2) of dialysis is by cavity centrifugation bull stick (6) of bottom, induction tube (8) of the inside top one side of cavity centrifugation bull stick (6), eduction tube (9) of the inside top opposite side of cavity centrifugation bull stick (6), the centrifugal dialysis motor (10) of inside middle part, leading-in appearance groove (11) of inside one side and negative pressure derivation appearance groove (12) of inside opposite side combine together to form.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021764278.3U CN213835125U (en) | 2020-08-21 | 2020-08-21 | Protein dialysis device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021764278.3U CN213835125U (en) | 2020-08-21 | 2020-08-21 | Protein dialysis device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213835125U true CN213835125U (en) | 2021-07-30 |
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ID=77003161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021764278.3U Active CN213835125U (en) | 2020-08-21 | 2020-08-21 | Protein dialysis device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213835125U (en) |
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2020
- 2020-08-21 CN CN202021764278.3U patent/CN213835125U/en active Active
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| GR01 | Patent grant | ||
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Address after: Building 10, No. 78 Keling Road, Science and Technology City, High tech Zone, Suzhou City, Jiangsu Province, 215163, 202-5 Patentee after: Suzhou Lvzheng Biotechnology Co.,Ltd. Country or region after: China Address before: No. 50 Zhongling Street, Xuanwu District, Nanjing City, Jiangsu Province, 210000 Patentee before: Nanjing lvzheng Biotechnology Co.,Ltd. Country or region before: China |