CN213779995U - Defoaming device for HPLC experiments - Google Patents
Defoaming device for HPLC experiments Download PDFInfo
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- CN213779995U CN213779995U CN202022626023.7U CN202022626023U CN213779995U CN 213779995 U CN213779995 U CN 213779995U CN 202022626023 U CN202022626023 U CN 202022626023U CN 213779995 U CN213779995 U CN 213779995U
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- mobile phase
- phase container
- compatilizer
- mobile
- helium gas
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Abstract
The utility model provides a defoaming device for HPLC experiments, hold the chamber including mobile compatilizer, mobile phase container holds the chamber bottom and is provided with ultrasonic oscillator, this mobile phase container holds intracavity portion and is provided with mobile compatilizer standing groove, mobile compatilizer is placed in mobile compatilizer standing groove, the last circulation of gas lid that has set of this mobile phase container, be provided with helium intake pipe and outlet duct on the circulation of gas lid, the helium intake pipe stretches into to mobile phase container bottom, evenly be provided with a plurality of aeration holes in this helium intake pipe, mobile phase container holds intracavity splendid attire and is equipped with liquid, be provided with spacing retaining ring in the mobile compatilizer standing groove, spacing retaining ring passes through the spring and links to each other with mobile compatilizer standing groove inner wall, mobile phase container holds the chamber outer wall and is provided with the time. The utility model has the advantages of simple structure, simple operation and good degassing effect.
Description
Technical Field
The utility model belongs to the technical field of the HPLC experimental facilities, especially, relate to a defoaming device for HPLC experiments.
Background
High Performance Liquid Chromatography (High Performance Liquid Chromatography, HPLC) is an important branch of Chromatography, in which Liquid is used as a mobile phase, a High-pressure infusion system is adopted, mobile phases such as single solvents with different polarities or mixed solvents, buffers and the like with different proportions are pumped into a chromatographic column filled with a stationary phase, and after components in the column are separated, the mobile phases enter a detector for detection, so that analysis of a sample is realized. The method becomes an important separation and analysis technology application in the subject fields of chemistry, medicine, industry, agriculture, commodity inspection, law inspection and the like.
Before the mobile phase enters the chromatographic column, defoaming treatment is carried out, because the existence of bubbles in the mobile phase causes sharp noise peaks on a chromatogram, the analysis sensitivity is reduced in serious cases, and the flow velocity of the mobile phase is slowed or unstable when the bubbles grow into a flow path or the chromatographic column, so that a base line fluctuates, therefore, a flow defoaming step is a very necessary and important step, but the problem of unsatisfactory degassing and defoaming frequently occurs at present, and the whole experiment is further influenced.
Disclosure of Invention
The to-be-solved problem of the utility model is to provide a defoaming device for HPLC experiments of simple structure, simple operation, degasification are effectual.
In order to solve the technical problem, the utility model discloses a technical scheme is: the utility model provides a defoaming device for HPLC experiments, holds the chamber including the mobile phase container, the mobile phase container holds the chamber bottom and is provided with ultrasonic oscillator, and this mobile phase container holds intracavity portion and is provided with the mobile phase container standing groove, and the mobile phase container is placed in the mobile phase container standing groove, has set the gas circulation lid on this mobile phase container, be provided with helium intake pipe and outlet duct on the gas circulation lid, the helium intake pipe stretches into to mobile phase container bottom, evenly is provided with a plurality of aeration holes in this helium intake pipe, the mobile phase container holds the intracavity splendid attire and is equipped with liquid.
And a limiting retainer ring is arranged in the flow compatilizer placing groove.
The limiting retainer ring is connected with the inner wall of the placing groove of the flow compatilizer through a spring.
The outer wall of the flow compatilizer containing cavity is provided with a timer.
Because of adopting the technical proposal, the utility model has simple structure, when in use, the mobile phase container is placed in the mobile phase container placing groove, and the displacement or the dumping is avoided by the limit of the limit retainer ring, at the moment, the mobile phase container is surrounded by liquid, then the gas circulation cover body with the helium gas inlet pipe and the gas outlet pipe is arranged at the bottle mouth of the mobile phase container, the helium gas inlet pipe is extended to the bottom of the mobile phase container, then the helium gas is slowly input into the mobile phase from the aeration hole of the helium gas inlet pipe, the air which is dissolved in the mobile phase is removed, because the solubility of the helium gas in the mobile phase is extremely low, the input helium gas can be discharged through the gas outlet pipe, simultaneously, the ultrasonic oscillator is opened, the prepared mobile phase container is ultrasonically degassed together in the mobile phase container placing groove, the double degassing guarantee is realized, the degassing effect is good, the timer of the outer wall of the cavity is placed through the mobile phase container during the operation, the operation is convenient.
The utility model has the advantages that: has the advantages of simple structure, convenient operation and good degassing effect.
Drawings
The advantages and mode of realisation of the invention will become more apparent hereinafter by describing in detail the invention with reference to the attached drawings, wherein the content shown in the drawings is only for explaining the invention, without constituting any limitation to the meaning of the invention, in which:
FIG. 1 is a schematic structural diagram of the present invention
In the figure:
1. a mobile compatilizer holding cavity 2, an ultrasonic oscillator 3 and a mobile phase container holding groove
4. Mobile phase container 5, gas circulation cover 6, helium gas inlet pipe
7. Outlet pipe 8, aeration hole 9, spacing retainer ring
10. Time-meter
Detailed Description
As shown in figure 1, the utility model relates to a defoaming device for HPLC experiments, which comprises a mobile phase container holding cavity 1, an ultrasonic oscillator 2 arranged at the bottom of the mobile phase container holding cavity 1, the mobile phase vessel containing cavity 1 is internally provided with a mobile phase vessel placing groove 3, a mobile phase vessel 4 is placed in the mobile phase vessel placing groove 3, a gas circulation cover body 5 is arranged on the mobile phase container 4, a helium gas inlet pipe 6 and a helium gas outlet pipe 7 are arranged on the gas circulation cover body 5, the helium gas inlet pipe 6 extends into the bottom of the mobile phase container 4, evenly be provided with a plurality of aeration holes 8 on this helium intake pipe 6, the mobile phase container holds the intracavity 1 and is equipped with water, is provided with spacing retaining ring 9 in the mobile phase container standing groove 3, and spacing retaining ring 9 passes through the spring and links to each other with 3 inner walls of mobile phase container standing groove, and the mobile phase container holds the intracavity 1 outer wall and is provided with time-recorder 10.
The utility model has simple structure, when in use, put the mobile phase container 4 into the mobile phase container placing groove 3, and avoid displacement or toppling over through the spacing of the spacing retaining ring 9, at the moment, the mobile phase container 4 is surrounded by water, then the gas circulation lid 5 with the helium gas inlet pipe 6 and the outlet duct 7 is covered at the bottleneck of the mobile phase container 4, the helium gas inlet pipe 6 is extended to the bottom of the mobile phase container 4, then the helium gas is slowly input into the mobile phase from the aeration hole 8 of the helium gas inlet pipe 6, the air which is dissolved in the mobile phase is removed, because the solubility of the helium gas in the mobile phase is extremely low, the input helium gas can be discharged through the outlet duct, meanwhile, the ultrasonic oscillator 2 is opened, the prepared mobile phase container is ultrasonically degassed together in the mobile phase container placing groove, the double degassing guarantee is realized, the degassing defoaming effect is good, the timer 10 of the outer wall of the cavity 1 is held through the mobile phase container during operation, the operation is convenient.
The embodiments of the present invention have been described in detail, but the description is only for the preferred embodiments of the present invention and should not be construed as limiting the scope of the present invention. All equivalent changes and modifications made within the scope of the present invention should be covered by the present patent.
Claims (4)
1. A defoaming device for HPLC experiments is characterized in that: the ultrasonic treatment device comprises a mobile phase container containing cavity, wherein an ultrasonic oscillator is arranged at the bottom of the mobile phase container containing cavity, a mobile phase container placing groove is formed in the inner part of the mobile phase container containing cavity, the mobile phase container is placed in the mobile phase container placing groove, a gas circulation cover body is arranged on the mobile phase container in a matched mode, a helium gas inlet pipe and a helium gas outlet pipe are arranged on the gas circulation cover body, the helium gas inlet pipe extends into the bottom of the mobile phase container, a plurality of aeration holes are evenly formed in the helium gas inlet pipe, and liquid is contained in the mobile phase container containing cavity.
2. The defoaming apparatus for HPLC experiments according to claim 1, characterized in that: and a limiting retainer ring is arranged in the flow compatilizer placing groove.
3. The defoaming apparatus for HPLC experiments according to claim 2, characterized in that: the limiting retainer ring is connected with the inner wall of the placing groove of the flow compatilizer through a spring.
4. The defoaming apparatus for HPLC experiments according to claim 1, characterized in that: the outer wall of the flow compatilizer containing cavity is provided with a timer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022626023.7U CN213779995U (en) | 2020-11-13 | 2020-11-13 | Defoaming device for HPLC experiments |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022626023.7U CN213779995U (en) | 2020-11-13 | 2020-11-13 | Defoaming device for HPLC experiments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213779995U true CN213779995U (en) | 2021-07-23 |
Family
ID=76918042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022626023.7U Active CN213779995U (en) | 2020-11-13 | 2020-11-13 | Defoaming device for HPLC experiments |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213779995U (en) |
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2020
- 2020-11-13 CN CN202022626023.7U patent/CN213779995U/en active Active
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