CN213762193U - Entecavir preparation is with high-efficient jet milling equipment - Google Patents
Entecavir preparation is with high-efficient jet milling equipment Download PDFInfo
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- CN213762193U CN213762193U CN202022069835.6U CN202022069835U CN213762193U CN 213762193 U CN213762193 U CN 213762193U CN 202022069835 U CN202022069835 U CN 202022069835U CN 213762193 U CN213762193 U CN 213762193U
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- dust box
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- 229960000980 entecavir Drugs 0.000 title claims abstract description 19
- YXPVEXCTPGULBZ-WQYNNSOESA-N entecavir hydrate Chemical compound O.C1=NC=2C(=O)NC(N)=NC=2N1[C@H]1C[C@H](O)[C@@H](CO)C1=C YXPVEXCTPGULBZ-WQYNNSOESA-N 0.000 title claims abstract description 19
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 238000010902 jet-milling Methods 0.000 title abstract description 6
- 239000000428 dust Substances 0.000 claims abstract description 48
- 230000003139 buffering effect Effects 0.000 claims abstract description 25
- 229910001220 stainless steel Inorganic materials 0.000 claims abstract description 12
- 239000010935 stainless steel Substances 0.000 claims abstract description 12
- 239000002699 waste material Substances 0.000 claims abstract description 12
- 239000000463 material Substances 0.000 claims description 16
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 8
- 239000000741 silica gel Substances 0.000 claims description 8
- 229910002027 silica gel Inorganic materials 0.000 claims description 8
- 238000013016 damping Methods 0.000 claims description 6
- 239000010813 municipal solid waste Substances 0.000 claims 1
- 230000002349 favourable effect Effects 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 6
- 230000035939 shock Effects 0.000 abstract description 6
- 230000001681 protective effect Effects 0.000 description 3
- 239000003814 drug Substances 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 239000011435 rock Substances 0.000 description 2
- SUFNCOCCSOVPCQ-ORXWAGORSA-N 2-amino-9-[(2r,3r,4s,5r)-2-cyclopentyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purin-6-one Chemical class C1=NC=2C(=O)NC(N)=NC=2N1[C@]1(C2CCCC2)O[C@H](CO)[C@@H](O)[C@H]1O SUFNCOCCSOVPCQ-ORXWAGORSA-N 0.000 description 1
- 208000000419 Chronic Hepatitis B Diseases 0.000 description 1
- 241000700721 Hepatitis B virus Species 0.000 description 1
- 102000003929 Transaminases Human genes 0.000 description 1
- 108090000340 Transaminases Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 208000002672 hepatitis B Diseases 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 230000029812 viral genome replication Effects 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
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Abstract
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Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202022069835.6U CN213762193U (en) | 2020-09-21 | 2020-09-21 | Entecavir preparation is with high-efficient jet milling equipment |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN202022069835.6U CN213762193U (en) | 2020-09-21 | 2020-09-21 | Entecavir preparation is with high-efficient jet milling equipment |
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CN213762193U true CN213762193U (en) | 2021-07-23 |
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CN202022069835.6U Active CN213762193U (en) | 2020-09-21 | 2020-09-21 | Entecavir preparation is with high-efficient jet milling equipment |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114472440A (en) * | 2022-01-20 | 2022-05-13 | 青岛国海生物制药有限公司 | Dust absorption rubbing crusher for preparation |
-
2020
- 2020-09-21 CN CN202022069835.6U patent/CN213762193U/en active Active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114472440A (en) * | 2022-01-20 | 2022-05-13 | 青岛国海生物制药有限公司 | Dust absorption rubbing crusher for preparation |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20221201 Address after: 255000 High-tech Zone, Zibo City, Shandong Province, No. 51 Lutai Avenue, Block A, Seven Floors of Polymer Material Industry Innovation Park Patentee after: Shandong Zibo Haiya Pharmaceutical Co.,Ltd. Address before: 255000 7 / F, block a, polymer materials Industrial Innovation Park, No. 51, Lutai Avenue, high tech Zone, Zibo City, Shandong Province Patentee before: Shandong Haiya Pharmaceutical Technology Co.,Ltd. |
|
TR01 | Transfer of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: A backup high-efficiency airflow crushing equipment for Entecavir production Effective date of registration: 20230411 Granted publication date: 20210723 Pledgee: Dongying Bank Co.,Ltd. Zibo Branch Pledgor: Shandong Zibo Haiya Pharmaceutical Co.,Ltd. Registration number: Y2023980037757 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Granted publication date: 20210723 Pledgee: Dongying Bank Co.,Ltd. Zibo Branch Pledgor: Shandong Zibo Haiya Pharmaceutical Co.,Ltd. Registration number: Y2023980037757 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: A backup high-efficiency airflow crushing equipment for Entecavir production Granted publication date: 20210723 Pledgee: Dongying Bank Co.,Ltd. Zibo Branch Pledgor: Shandong Zibo Haiya Pharmaceutical Co.,Ltd. Registration number: Y2024980012479 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |