CN213759574U - Tablet structure - Google Patents

Abstract

The utility model provides a tablet structure, the tablet structure includes first segment, second segment and connecting axle, first segment and second segment symmetry just all are the water droplet form, the connecting axle is cylindrical, the both ends of connecting axle are connected respectively in the first segment in the one end I of broad and the second segment in the one end II of broad, the longest distance of the one end I of broad and narrower one end III in the first segment is 5~10 mm, the longest distance of the one end II of broad and narrower one end IV in the second segment is 5~10 mm, the height of connecting axle is 1~3 mm, the diameter of connecting axle is 3~5 mm; the utility model provides a tablet structure, whole pleasing to the eye can alleviate patient's resistance psychology, and the dose control of being convenient for has higher using value and better application prospect.

Description

Tablet structure

Technical Field

The utility model belongs to the field of medicinal preparations, a tablet structure is related to.

Background

The tablet is a flaky or specially-shaped flaky solid preparation which is prepared by uniformly mixing the medicament and auxiliary materials and then pressing. It has many advantages: generally, the dissolution rate and the bioavailability of the tablet are better than those of pills; the dosage is accurate, and the content difference of the medicine in the tablet is small; the quality is stable, the tablet is a dry solid, certain medicines which are easy to oxidize and deteriorate and easy to deliquesce can be protected by coating, and the influence of light, air, moisture and the like on the medicines is small; convenient to take, carry and transport; mechanized production, large output, low cost and easy reaching of sanitary standard.

However, the existing tablet has the advantages of uniform structure and single shape, and the structure of part of the tablet can not relieve the tension of patients, so that the patients can resist taking the medicine; in addition, every piece quality is fixed at present in the tablet structure, is overall structure, is not convenient for cut apart the tablet and eat, therefore how conveniently to control the dose, avoids appearing this problem, has important meaning to its clinical application.

SUMMERY OF THE UTILITY MODEL

Not enough to prior art, the utility model aims to provide a tablet structure to solve the medicine shape and be unfavorable for the dose control and lead to using medicine excessive problem, reach the control dose of being convenient for, promote the purpose of patient appetite.

To achieve the purpose, the utility model adopts the following technical proposal:

the utility model provides a tablet structure, the tablet structure includes first fragment, second fragment and connecting axle, first fragment and second fragment symmetry just all are the water droplet form, the connecting axle is cylindrical, the one end I of broad in the first fragment and the one end II of broad in the second fragment are connected respectively to the both ends of connecting axle, the one end I of broad is 5~10 mm with the longest distance of narrower one end III in the first fragment, the one end II of broad is 5~10 mm with the longest distance of narrower one end IV in the second fragment, the height of connecting axle is 1~3 mm, the diameter of connecting axle is 3~5 mm.

Wherein the longest distance between the wider end I and the narrower end III in the first segment may be 5 mm, 5.5 mm, 6 mm, 7 mm, 7.5 mm, 8 mm, 8.5 mm, 9 mm, 9.5 mm, 10 mm, etc.

The longest distance between the wider end II and the narrower end IV in the second segment is 5-10 mm, and may be, for example, 5 mm, 5.5 mm, 6 mm, 6.5 mm, 7 mm, 7.1 mm, 7.6 mm, 8.3 mm, 9 mm, 9.2 mm, 9.5 mm, or 10 mm.

The height of the connecting shaft is 1-3 mm, for example, 1 mm, 1.3 mm, 1.5 mm, 2 mm, 2.4 mm, 2.8 mm or 3 mm.

The diameter of the connecting shaft is 3-5 mm, for example, 3 mm, 3.1 mm, 3.5 mm, 3.7 mm, 3.9 mm, 4 mm, 4.5 mm, 4.7 mm, 4.8 mm or 5 mm.

Preferably, the connecting shaft is provided with a plurality of grooves I.

Preferably, the number of the grooves I is 1 or 2.

Preferably, the depth of the groove I is 1-2 mm, for example, 1 mm, 1.5 mm or 2 mm.

Preferably, the thickness of the first segment corresponds to the diameter of the connecting shaft.

Preferably, the thickness of the second segment corresponds to the diameter of the connecting shaft.

Preferably, the first and second segments are provided with a pattern on both the upper and lower faces.

Preferably, the first and second segments are laterally provided with a groove II.

Preferably, the depth of the groove II is 0.2-0.5 mm, such as 0.2 mm, 0.3 mm, 0.4 mm, 0.5 mm, etc.

The first segment, the second segment and the connecting shaft of the utility model are all prepared from common drugs, such as common drugs like apixaban, methocarbamol, ciprofloxacin hydrochloride, itopride hydrochloride, etc.

Compared with the prior art, the beneficial effects of the utility model are that:

(1) the utility model makes the tablet into symmetrical water drop shape and sets the pattern, which improves the aesthetic degree of the tablet, reduces the degree of the psychological resistance of postoperative patients to taking medicine, is convenient for improving the desire to take medicine and relieves the psychology of the patients; meanwhile, due to the special shape, the cognition degree of the medicine in the public is favorably improved.

(2) The utility model discloses a set up the connecting axle, divide into two parts with the tablet, be convenient for cut apart the tablet, the dose control of being convenient for use medicine can avoid using medicine excessively to lead to the problem that the risk of bleeding risees at the in-process of using medicine.

(3) The utility model can increase the surface area of the side surface of the tablet through the groove II, which is convenient for controlling the drug bearing capacity of the tablet; in addition, the proportion of the water drops is adjusted and coordinated, so that the size of the tablet is moderate, and the aesthetic degree of the tablet is further improved.

Drawings

Fig. 1 is a top view of a tablet structure provided in embodiment 1 of the present invention;

fig. 2 is a front view of a tablet structure provided in embodiment 2 of the present invention;

fig. 3 is a top view of a tablet structure provided in embodiment 3 of the present invention;

fig. 4 is a side view of a tablet structure provided in embodiment 3 of the present invention;

in fig. 1-4, 1-first segment, 101-narrower end III in first segment, 102-wider end I in first segment, 103-groove II in first segment, 2-second segment, 201-narrower end IV in second segment, 202-wider end II in second segment, 3-connecting axis, 301-groove I in connecting axis.

Detailed Description

To better explain the present invention, the technical solution is easy to understand, and the present invention is further explained in detail below.

The utility model discloses below

Example 1

In this embodiment, taking apixaban tablet as an example, the first fragment, the second fragment and the connecting shaft used are all prepared from apixaban tablet, which is prepared by referring to example 1 in CN107773549A, and the details are as follows:

1. tablet core prescription: 2.5 g of apixaban, 60 g of lactose, 45 g of microcrystalline cellulose, 5 g of PVPK30, 8 g of low-substituted hydroxypropyl cellulose, a proper amount of 50% ethanol aqueous solution and 1 g of magnesium stearate, and the powder is prepared into 1000 tablets; 2. coating solution formula (1000 tablets): 5.1 g of coating powder and 64 mL of 50% ethanol.

The preparation method comprises the following steps: sieving lactose, microcrystalline cellulose, PVPK30 and low-substituted hydroxypropyl cellulose with a 80-mesh sieve, grinding the main drug for 2 hours, sieving with a 120-mesh sieve, uniformly mixing the powder containing the main drug with the lactose, the microcrystalline cellulose, the PVPK30 and the low-substituted hydroxypropyl cellulose according to the prescription amount, preparing a soft material by using a 50% ethanol aqueous solution, granulating by using a 24-mesh sieve, drying at 50 ℃, granulating by using a 22-mesh sieve, adding magnesium stearate according to the prescription amount, uniformly mixing, tabletting, pressing into a target shape, and putting into a coating pot to coat and increase the weight to 3%.

A tablet structure is specifically shown in figure 1 (a top view of a tablet) and comprises a first segment 1, a second segment 2 and a connecting shaft 3, wherein the first segment 1 and the second segment 2 are symmetrical and are both in a water-drop shape, and the water-drop shape is special, so that the aesthetic degree of the tablet is integrally improved, the psychological resistance degree of postoperative patients to taking medicine can be reduced, the medication desire can be conveniently improved, and the psychology of the patients can be relieved; the connecting shaft 3 is cylindrical, two ends of the connecting shaft 3 are respectively connected with a wider end I102 in the first segment 1 and a wider end II 202 in the second segment 2, the longest distance between the wider end I102 and the narrower end III 101 in the first segment 1 is 8 mm, the longest distance between the wider end II 202 and the narrower end IV 201 in the second segment 2 is 8 mm, the height of the connecting shaft is 2 mm, and the diameter of the connecting shaft is 3 mm.

The utility model discloses the distance of the one end of well broad and narrower one end means the summit of the point angle of water droplet form to the distance of water droplet form and connecting axle contact point. For example, in the present embodiment, the longest distance between the wider end I and the narrower end III in the first segment refers to the distance from the vertex of the tip angle of the narrower end III 101 in the first segment 1 to the intersection of the connecting shaft 3 and the wider end I102 of the first segment 1.

The height of the connecting axis 3 refers to the distance between the connecting first segment 1 and the second segment 2.

Example 2

The embodiment provides a tablet structure, still taking apixaban tablet as an example, please continue to refer to fig. 1, and refer to fig. 2 (a front view of the tablet), which includes a first segment 1, a second segment 2 and a connecting shaft 3, wherein the first segment 1 and the second segment 2 are symmetrical and both in a droplet shape, and because the droplet shape is special, the aesthetic degree of the tablet is integrally improved, the degree of psychological resistance of postoperative patients to taking medicine can be reduced, the desire to take medicine is facilitated, and the psychological resistance of patients is relieved; connecting axle 3 is cylindrical, is provided with 2 recesses I301, and the tablet can be based on actual use medicine needs, cuts apart the tablet into 2 parts in recess I department, and every part can all use medicine alone, also can not cut apart the tablet, uses medicine jointly. The dosage of using of convenient control like this can avoid the problem of the large amount of loss of dosage when cutting apart, can avoid using the excessive problem that leads to the risk of just bleeding to rise of medicine simultaneously. If only one short connecting shaft is arranged, the tablet is inconvenient to quantitatively cut, so that the loss of the medicine amount is overlarge in the cutting process, and the medicine amount is not accurate enough; the depth of the groove I301 is 1 mm, two ends of the connecting shaft 3 are respectively connected with the wider end I102 in the first segment 1 and the wider end II 202 in the second segment 2, the longest distance between the wider end I102 and the narrower end III 101 in the first segment 1 is 9 mm, the longest distance between the wider end II 202 and the narrower end IV 201 in the second segment 2 is 9 mm, the height of the connecting shaft 3 is 3 mm, the diameter of the connecting shaft 3 is 3 mm, and the thicknesses of the first segment 1 and the second segment 2 are consistent with the diameter of the connecting shaft 3.

Example 3

In this embodiment, taking the methocarbamol tablet as an example, the first segment, the second segment and the connecting shaft used are all prepared from the methocarbamol tablet, and the specific method is as follows: 500g of methocarbamol is crushed and sieved by a 200-mesh sieve for standby, and the croscarmellose sodium, the microcrystalline cellulose and the lactose are sieved by a 100-mesh sieve for standby. Weighing, mixing and granulating: preparing soft material with 50% ethanol solution, granulating with 20 mesh nylon net, making granule with less fine powder, neatly without strip, drying, grading with 16 mesh sieve, adding lubricant, mixing, placing in a sealed container, testing, and tabletting.

The embodiment provides a tablet structure, referring to fig. 2, fig. 3 (top view of tablet), fig. 4 (side view of first segment of tablet) including first segment 1, second segment 2 and connecting shaft 3, where the first segment 1 and the second segment 2 are symmetrical and both in drop shape, the connecting shaft 3 is cylindrical and is provided with 2 grooves I301, the tablet can be divided into 2 parts at the groove I according to actual medication requirements, the depth of the groove I301 is 1 mm, two ends of the connecting shaft 3 are respectively connected with the wider end I102 in the first segment 1 and the wider end II 202 in the second segment 2, the longest distance between the wider end I102 and the narrower end III 101 in the first segment 1 is 9 mm, the longest distance between the wider end II 202 and the narrower end IV 201 in the second segment 2 is 9 mm, the height of the connecting shaft 3 mm, the diameter of the connecting shaft 3 is 3 mm, the thicknesses of the first segment 1 and the second segment 2 are consistent with the diameter of the connecting shaft 3, patterns are arranged on the upper surface and the lower surface of the first segment 1 and the second segment 2, the patterns are smiling faces, the good feeling of medicine taking of a patient can be improved, and the patterns can be any patterns and are designed freely; the side surface is provided with a groove II 103, the surface area of the tablet is larger while the effective medicine content of the tablet is ensured by the design of the groove II, the actual medicine absorption is facilitated, the depth of the groove II 103 is 0.4 mm, and the side view of the first segment 1 is taken as an example in the attached figure 4.

The present invention is described in detail by the above embodiments, but the present invention is not limited to the above detailed process equipment and process flow, i.e. not meaning the present invention must rely on the above detailed process equipment and process flow to implement. It should be clear to those skilled in the art that any improvement of the present invention, to the equivalent replacement of each raw material of the present invention, the addition of auxiliary components, the selection of specific modes, etc., all fall within the protection scope and disclosure scope of the present invention.

Claims (9)

1. The utility model provides a tablet structure, its characterized in that, tablet structure includes first fragment (1), second fragment (2) and connecting axle (3), first fragment (1) and second fragment (2) symmetry just all are the drop form, connecting axle (3) are cylindrical, the both ends of connecting axle (3) are connected respectively in first fragment (1) one end I (102) of broad and the second fragment in one end II (202) of broad, in first fragment (1) one end I (102) of broad is 5~10 mm with the longest distance of narrower one end III (101), in second fragment (2) one end II (202) of broad is 5~10 mm with the longest distance of narrower one end IV (201), the height of connecting axle (3) is 1~3 mm, the diameter of connecting axle (3) is 3~5 mm.

2. Tablet structure according to claim 1, characterized in that the connecting shaft (3) is provided with several grooves I (301).

3. Tablet structure according to claim 2, characterized in that the number of grooves I (301) is 1 or 2.

4. A tablet structure according to claim 2 or 3, characterized in that the depth of the groove I (301) is 1-2 mm.

5. Tablet structure according to claim 1, characterized in that the thickness of the first segment (1) corresponds to the diameter of the connecting shaft (3).

6. Tablet structure according to claim 1, characterized in that the thickness of the second segment (2) corresponds to the diameter of the connecting shaft (3).

7. Tablet structure according to claim 1, characterized in that the first segment (1) and the second segment (2) are provided with a pattern on both the upper and lower side.

8. Tablet structure according to claim 1, characterized in that the first segment (1) and the second segment (2) are flanked by grooves II (103).

9. The tablet structure of claim 8, wherein the depth of the groove II (103) is 0.2-0.5 mm.

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