CN213749612U - Portable kit for surface-enhanced Raman spectroscopy detection - Google Patents
Portable kit for surface-enhanced Raman spectroscopy detection Download PDFInfo
- Publication number
- CN213749612U CN213749612U CN202022156459.4U CN202022156459U CN213749612U CN 213749612 U CN213749612 U CN 213749612U CN 202022156459 U CN202022156459 U CN 202022156459U CN 213749612 U CN213749612 U CN 213749612U
- Authority
- CN
- China
- Prior art keywords
- detection
- drawer
- box body
- raman spectroscopy
- enhanced raman
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The utility model relates to a portable kit for surface enhanced Raman spectroscopy detection, which comprises a box body, a box cover rotationally arranged on the box body, a plurality of detection position holes arranged at the top of the box body, and a detection drawer component slidably embedded on the side surface of the box body; wherein the detection drawer component comprises a detection drawer which is embedded in the side face of the box body in a sliding manner, detection test paper arranged on the detection drawer, and a plurality of silver colloid detection sites which are arranged on the detection test paper at intervals and correspond to the detection site holes. Compared with the prior art, the utility model discloses preparation low cost conveniently preserves and carries, and sample cross contamination in disposable can avoiding detecting, and test paper changes convenient to use, is favorable to the big quick analysis of sample in batches in laboratory and the quick big quick analysis demand in batches in field pollution sources scene in batches, has comparatively wide application prospect in emergency analysis and judicial appraisal field.
Description
Technical Field
The utility model belongs to the technical field of chemical analysis, a portable kit for surface enhanced Raman spectroscopy detects is related to.
Background
In recent years, water pollution accidents in China frequently occur, and particularly, improper behaviors in the processes of production, transportation, use and even abandonment of organic chemicals become the chief culprit of water environment pollution, and serious accidents of safety and environmental pollution are easily caused. With the improvement of environmental analysis level, antibiotics, endocrine disruptors, carcinogenic polycyclic aromatic hydrocarbons and other new chemical pollutants (ECPs) are frequently detected in domestic and foreign municipal sewage, surface water and drinking water, are easy to biologically accumulate, have potential ecological and health threats and are great in harm. However, effective detection technology and standard monitoring method for the detection are not available, and great challenges are brought to emergency analysis of water pollution accidents and daily water environment monitoring.
The Surface Enhanced Raman Spectroscopy (SERS) is an analysis technology for characterizing substances adsorbed on the surface of a rough precious metal on a molecular level, has the advantages of short detection time, high sensitivity, small water interference, direct in-situ analysis and the like, and needs a small amount of samples without a complex sample pretreatment process. In practical application, especially in some environments requiring extremely low detection limit, such as residue detection of dye molecules, detection of forbidden drugs, detection of carcinogenic substances in food additives, and detection of pesticide residue, the method has wide application.
Currently, there are some problems in the research based on surface enhanced raman spectroscopy detection, such as: the metal nanoparticles with SERS activity are poor in encapsulation performance, need to be prepared freshly, are easy to cause self-aggregation after being stored for a long time, are low in stability and inconvenient to carry, and therefore sensitivity of the metal nanoparticles is affected. Therefore, the development of the SERS portable kit device which is simple and convenient to manufacture and use and has high sensitivity and high stability is significant.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a portable kit for surface enhancement raman spectroscopy detects for solve because the metal nanoparticle encapsulation nature of current surface enhancement raman spectroscopy detection usefulness is not good, lead to its portability relatively poor, be difficult to realize the problem of witnessed inspections.
The purpose of the utility model can be realized through the following technical scheme:
a portable kit for surface-enhanced Raman spectroscopy detection comprises a box body, a box cover rotationally arranged on the box body, a plurality of detection position holes formed in the top of the box body, and a detection drawer assembly slidably embedded in the side face of the box body;
the detection drawer assembly comprises a detection drawer which is slidably embedded in the side face of the box body, detection test paper arranged on the detection drawer, and a plurality of silver colloid detection sites which are arranged on the detection test paper at intervals; the silver colloid detection sites correspond to the detection site holes one by one.
As a preferable technical scheme, the box body is 8-10mm high, 10-15cm long and 8-10cm wide, and the box cover is 5-8mm deep, so that the closed state of the portable kit is ensured.
In the detection site of the silver colloid, the preparation method of the silver colloid solution can be referred to the literature (Lee P C, Meisel D J. addition and surface-enhanced Raman of dye on silver and gold gases [ J ]. Journal of Physical Chemistry,1982,86(17):3391-3395.), or other silver colloid solutions commonly used in the surface enhanced Raman spectroscopy detection process can be selected.
As a preferred technical scheme, the box cover is a transparent box cover.
Furthermore, the silver colloid detection site array is arranged on the detection test paper.
As a preferred technical scheme, the silver colloid detection sites are arranged on the detection test paper in a mode of 3 rows and 5 columns.
Furthermore, the silver colloid detection sites are in a circular structure with the diameter of 8-12mm, and the distance between every two adjacent silver colloid detection sites is 10-15 mm.
Furthermore, the detection position holes are in a circular hole structure with the diameter of 10-15mm, and the distance between every two adjacent detection position holes is 8-12 mm.
Further, the detection test paper comprises a waterproof layer and a filter paper layer arranged on the waterproof layer, wherein the thickness of the waterproof layer is 0.5-1mm, and the thickness of the filter paper layer is 0.2-0.5 mm;
the silver colloid detection site is silk-screen printed on the filter paper layer.
The waterproof layer is used for preventing liquid samples from being polluted mutually or polluting the kit body.
Furthermore, a drawer cavity is formed in the front side of the box body, and the detection drawer is arranged in the drawer cavity in a sliding mode.
As a preferred technical scheme, the height of the drawer chamber is 3-5 mm.
Furthermore, the detection drawer comprises a test paper tray and a sealing baffle arranged at the front end of the test paper tray, the detection test paper is arranged on the test paper tray, the height of the sealing baffle is matched with the height of the drawer cavity, namely the height of the sealing baffle is slightly smaller than the height of the drawer cavity (0.1-0.2mm), so that the inner side of the sealing baffle can be just embedded into the drawer cavity.
As a preferable technical scheme, the height of the sealing baffle is 3-5mm, and the height of the test paper tray is 2-3 mm.
Furthermore, the test paper tray is also provided with a test paper fixing clamp for fixing the test paper, and the test paper fixing clamp comprises a rotating shaft fixed on the test paper tray and a pressing plate rotatably arranged on the rotating shaft.
As a preferable technical scheme, the length of the pressure plate is 5-8cm, and the pressure plate can flexibly rotate around the rotating shaft by 360 degrees.
Furthermore, the test paper fixing clamp is at least provided with two test paper fixing clamps which are respectively positioned at the corner parts of the test paper tray.
Furthermore, the portable kit also comprises a cover closing fixing component, wherein the cover closing fixing component comprises a fastening part connected to the front side of the box cover through a flexible belt and a positioning part arranged on the front side of the box body; and the positioning part is positioned below the drawer chamber.
Before use, printing the silver colloid on the surface of the test paper synthesized by common filter paper and waterproof paper by a screen printing technology to form a plurality of silver colloid detection sites, fixing the test paper on a test paper tray by a test paper fixing clamp, placing the test paper in a drawer cavity, and enabling detection site holes at the top of a box body to correspond to the silver colloid detection sites one by one, namely assembling to obtain the portable kit for surface enhanced Raman spectrum detection;
when the device is used, a pollutant sample to be detected is dripped or smeared to a silver colloid detection site, and then the surface enhanced Raman spectrum detection is carried out on the silver colloid detection site by using a Raman spectrometer. After all the silver colloid detection sites on the detection test paper are used, the detection drawer is pulled out, and the detection test paper can be put into use again after being replaced by new detection test paper.
Compared with the prior art, the utility model has the characteristics of it is following:
1) after the silver colloid is printed on the filter paper, the utility model can not self-assemble due to long time, and the sensitivity is not influenced;
2) the utility model discloses preparation low cost conveniently preserves and carries, and sample cross contamination in disposable can avoiding detecting, and test paper changes convenient to use, is favorable to the big quick analysis of sample in batches in laboratory and the big quick analysis demand in batches of field pollution source scene fast, has comparatively wide application prospect in emergency analysis and judicial appraisal field.
Drawings
FIG. 1 is a schematic diagram showing the structure of a portable kit for surface enhanced Raman spectroscopy in example 1;
FIG. 2 is a schematic view of the detection drawer;
FIG. 3 is a schematic diagram showing the distribution of the silver colloid detection sites on the test paper;
FIG. 4 is a schematic structural diagram of the test strip;
the notation in the figure is:
1-box body, 2-box cover, 3-detection position hole, 4-detection drawer, 401-test paper tray, 402-sealing baffle, 5-detection test paper, 6-silver glue detection position point, 7-rotating shaft, 8-pressing plate, 9-pressing plate, 10-fastening part and 11-positioning part.
Detailed Description
The present invention will be described in detail below with reference to the accompanying drawings and specific embodiments. The embodiment is implemented on the premise of the technical solution of the present invention, and a detailed implementation manner and a specific operation process are given, but the scope of the present invention is not limited to the following embodiments.
Example 1:
as shown in fig. 1 and fig. 3, the portable kit for surface-enhanced raman spectroscopy detection comprises a milky box body 1, a box cover 2 rotatably arranged on the box body 1, a drawer chamber which is arranged at the front side of the box body 1 and has a height of 3mm, detection position holes 3 arranged at the top of the box body 1 in an array manner, and a detection drawer assembly which is slidably embedded in the side surface of the box body 1; wherein the detection drawer component comprises a detection drawer 4 which is embedded in the side surface of the box body 1 in a sliding way, detection test paper 5 arranged on the detection drawer 4, and a silver colloid detection site 6 which is printed on the detection test paper 5 in a screen printing way and corresponds to the detection site hole 3.
Specifically, the box body 1 is 8mm high, 10cm long and 8cm wide, the box cover 2 is a transparent box cover, and the depth is 5mm, so as to ensure the closed state of the portable kit; the silver colloid detection sites 6 are distributed on the detection test paper 5 in 3 rows and 5 columns, the silver colloid detection sites 6 are in a circular structure with the diameter of 8mm, and the distance between every two adjacent silver colloid detection sites 6 is 10 mm. The detection position holes 3 are circular hole structures with the diameter of 10mm, and the distance between every two adjacent detection position holes 3 is 8 mm.
The detection test paper 5 comprises a waterproof layer 501 with the thickness of 0.5mm and a filter paper layer 502 with the thickness of 0.2mm arranged on the waterproof layer 501; the waterproof layer 501 is used for preventing liquid samples from being polluted mutually or polluting the kit body.
As shown in fig. 2, the detection drawer 4 includes a test paper tray 401 having a height of 2mm, a sealing baffle 402 disposed at a front end of the test paper tray 401 and having a height of 3mm, and test paper fixing clips disposed at a pair of corners of the sealing baffle 402, respectively, the test paper fixing clips include a rotating shaft 7 fixed on the test paper tray 401, and a pressing plate 8 rotatably disposed on the rotating shaft 7 and having a length of 5cm, and the pressing plate 9 is flexibly rotatable about a rotating shaft 7360 °.
In addition, the portable reagent kit also comprises a cover closing fixing component, and the cover closing fixing component comprises a fastening part 10 connected to the front side of the box cover 2 through a flexible belt 9 and a positioning part 11 arranged on the front side of the box body 1; and the positioning portion 11 is located below the drawer chamber.
Before use, printing silver colloid on the surface of a detection test paper 5 synthesized by common filter paper and waterproof paper through a screen printing technology to form a plurality of silver colloid detection sites 6, fixing the detection test paper 5 on a test paper tray 401 through a test paper fixing clamp, placing the test paper in a drawer cavity, and enabling detection site holes 3 in the top of a box body 1 to correspond to the silver colloid detection sites 6 one by one, namely assembling to obtain a portable kit for surface enhanced Raman spectrum detection;
when the device is used, a pollutant sample to be detected is dripped or smeared to the silver colloid detection site 6, and then the surface enhanced Raman spectroscopy detection is carried out on the silver colloid detection site 6 by using a Raman spectrometer. After all the silver colloid detection sites 6 on the detection test paper 5 are used, the detection drawer 4 is pulled out, and the detection test paper 5 can be put into use again after being replaced with new one.
Example 2:
in this example, the portable kit of example 1 was used to detect tetracycline in tap water from Fengxian district of Shanghai city. Taking a certain amount of sample, taking a water sample without theophylline as a blank, adding a theophylline standard solution with a certain mass concentration, carrying out a standard addition recovery experiment, carrying out SERS detection according to the using method, wherein the detection result is shown in Table 1.
TABLE 1
The sample is detected for 15 times, the RSD is less than 5%, the recovery rate is close to 100%, and the reagent detection kit is proved to have high stability and strong sensitivity.
Example 3:
in this embodiment, the box body 1 is 10mm high, and long 15cm, wide 10cm, and lid 2 is the transparent lid, and the degree of depth is 8mm, and the elargol detection site 6 is the circular structure of diameter 12mm, and the interval 15mm between the adjacent elargol detection site 6. The detection position holes 3 are of circular hole structures with the diameter of 15mm, the distance between every two adjacent detection position holes 3 is 12mm, and the detection test paper 5 comprises a waterproof layer 501 with the thickness of 1mm and a filter paper layer 502 with the thickness of 0.5mm arranged on the waterproof layer 501; the drawer chamber is 5mm high, and detection drawer 4 includes that the height is 3 mm's test paper tray 401, locates test paper tray 401 front end and height and is 5 mm's sealed baffle 402, and 8 long 5-8cm of clamp plate. The rest is the same as example 1.
Example 4:
in this embodiment, the box body 1 is 9mm high, and long 12cm, wide 9cm, and lid 2 is transparent lid, and the degree of depth is 6mm, and the elargol detection site 6 is the circular structure of diameter 10mm, and the interval 12mm between the adjacent elargol detection site 6. The detection position holes 3 are in circular hole structures with the diameter of 12mm, the distance between every two adjacent detection position holes 3 is 10mm, and the detection test paper 5 comprises a waterproof layer 501 with the thickness of 0.8mm and a filter paper layer 502 with the thickness of 0.4mm arranged on the waterproof layer 501; the drawer chamber is 4mm high, and detection drawer 4 includes that the height is the test paper tray 401 of 2.5mm, locates test paper tray 401 front end and the high sealed baffle 402 that is 4mm, and 8 long 6cm of clamp plate. The rest is the same as example 1.
The embodiments described above are intended to facilitate the understanding and use of the invention by those skilled in the art. It will be readily apparent to those skilled in the art that various modifications to these embodiments may be made, and the generic principles described herein may be applied to other embodiments without the use of the inventive faculty. Therefore, the present invention is not limited to the above embodiments, and those skilled in the art should make improvements and modifications within the scope of the present invention according to the disclosure of the present invention.
Claims (10)
1. A portable kit for surface-enhanced Raman spectroscopy detection is characterized by comprising a box body (1), a box cover (2) rotatably arranged on the box body (1), a plurality of detection position holes (3) formed in the top of the box body (1), and a detection drawer assembly slidably embedded in the side face of the box body (1);
the detection drawer component comprises a detection drawer (4) which is slidably embedded in the side surface of the box body (1), detection test paper (5) which is arranged on the detection drawer (4), and a plurality of silver colloid detection sites (6) which are distributed on the detection test paper (5) at intervals; the silver colloid detection sites (6) correspond to the detection site holes (3) one by one.
2. The portable kit for surface-enhanced raman spectroscopy according to claim 1, wherein the array of the silver colloid detection sites (6) is disposed on a test strip (5).
3. The portable kit for surface-enhanced Raman spectroscopy according to claim 1, wherein the silver colloid detection sites (6) have a circular structure with a diameter of 8-12mm, and the distance between adjacent silver colloid detection sites (6) is 10-15 mm.
4. The portable kit for surface-enhanced Raman spectroscopy according to claim 1, wherein the detection site holes (3) are circular holes with a diameter of 10-15mm, and the distance between adjacent detection site holes (3) is 8-12 mm.
5. The portable kit for surface-enhanced raman spectroscopy according to claim 1, wherein the test paper (5) comprises a waterproof layer (501) and a filter paper layer (502) disposed on the waterproof layer (501), wherein the waterproof layer (501) has a thickness of 0.5 to 1mm, and the filter paper layer (502) has a thickness of 0.2 to 0.5 mm;
the silver colloid detection site (6) is silk-screen printed on the filter paper layer (502).
6. The portable kit for surface-enhanced Raman spectroscopy according to claim 1, wherein a drawer chamber is opened at the front side of the case (1), and the detection drawer (4) is slidably disposed in the drawer chamber.
7. The portable kit for surface-enhanced Raman spectroscopy according to claim 6, wherein the detection drawer (4) comprises a test strip tray (401) and a sealing baffle (402) arranged at the front end of the test strip tray (401), the test strip (5) is arranged on the test strip tray (401), and the height of the sealing baffle (402) is matched with the height of the drawer chamber.
8. The portable reagent kit for surface-enhanced Raman spectroscopy according to claim 7, wherein the strip tray (401) is further provided with a strip fixing clip for fixing the test strip (5), and the strip fixing clip comprises a rotating shaft (7) fixed on the strip tray (401) and a pressing plate (8) rotatably arranged on the rotating shaft (7).
9. The portable reagent kit for surface-enhanced Raman spectroscopy according to claim 8, wherein the strip holder is provided with at least two strips and is respectively located at the corner of the strip tray (401).
10. The portable kit for surface-enhanced Raman spectroscopy according to claim 6, further comprising a cover-closing fixing component, wherein the cover-closing fixing component comprises a fastening part (10) connected to the front side of the box cover (2) through a flexible belt (9) and a positioning part (11) arranged on the front side of the box body (1); and the positioning part (11) is positioned below the drawer chamber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022156459.4U CN213749612U (en) | 2020-09-27 | 2020-09-27 | Portable kit for surface-enhanced Raman spectroscopy detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022156459.4U CN213749612U (en) | 2020-09-27 | 2020-09-27 | Portable kit for surface-enhanced Raman spectroscopy detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213749612U true CN213749612U (en) | 2021-07-20 |
Family
ID=76847058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022156459.4U Active CN213749612U (en) | 2020-09-27 | 2020-09-27 | Portable kit for surface-enhanced Raman spectroscopy detection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213749612U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114199862A (en) * | 2021-11-26 | 2022-03-18 | 中国汽车技术研究中心有限公司 | Multi-test-paper detection method, test paper box and multi-test-paper detection system |
-
2020
- 2020-09-27 CN CN202022156459.4U patent/CN213749612U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114199862A (en) * | 2021-11-26 | 2022-03-18 | 中国汽车技术研究中心有限公司 | Multi-test-paper detection method, test paper box and multi-test-paper detection system |
| CN114199862B (en) * | 2021-11-26 | 2024-04-30 | 中国汽车技术研究中心有限公司 | Multi-test-paper detection method, test-paper box and multi-test-paper detection system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Govindhan et al. | Electrochemical sensor based on carbon nanotubes for the simultaneous detection of phenolic pollutants | |
| Barek et al. | Electrochemical methods for monitoring of environmental carcinogens | |
| Balbino et al. | Voltammetric determination of Δ9-THC in glassy carbon electrode: An important contribution to forensic electroanalysis | |
| Xu et al. | Determination of trace amounts of dopamine by flow‐injection analysis coupled with luminol–Ag (III) complex chemiluminescence detection | |
| Absalan et al. | Design of a cyanide ion optode based on immobilization of a new Co (III) Schiff base complex on triacetylcellulose membrane using room temperature ionic liquids as modifiers | |
| Mao et al. | based nanosensors to evaluate community-wide illicit drug use for wastewater-based epidemiology | |
| Fuwei et al. | Molecular imprinting-chemiluminescence sensor for the determination of amoxicillin | |
| CN213749612U (en) | Portable kit for surface-enhanced Raman spectroscopy detection | |
| CN103674946A (en) | Color-sensitive gas sensing array based on nanofiber gas enrichment and preparation method thereof | |
| Chen | Carbon nanotube and diamond as electrochemical detectors in microchip and conventional capillary electrophoresis | |
| Li et al. | Highly sensitive and selective detection of naproxen via molecularly imprinted carbon dots as a fluorescent sensor | |
| Gong et al. | Nickel oxide and nickel co‐doped graphitic carbon nitride nanocomposites and its octylphenol sensing application | |
| Zare-Dorabei et al. | Lanthanum (III) ion determination by a new design optical sensor | |
| Wang et al. | Inorganic–organic hybrid coating material for the online in‐tube solid‐phase microextraction of monohydroxy polycyclic aromatic hydrocarbons in urine | |
| Zhang et al. | A novel cucurbit [7] uril anchored bis-functionalized metal-organic framework hybrid and its potential use in fluorescent analysis of illegal stimulants in saliva | |
| CN110540203A (en) | preparation method and application of badam shell-based nitrogen-doped nano porous carbon material | |
| Alizadeh et al. | Headspace-solid-phase microextraction using a dodecylsulfate-doped polypyrrole film coupled to ion mobility spectrometry for analysis methyl tert-butyl ether in water and gasoline | |
| Liang et al. | Construction of integrated and portable fluorescence sensor and the application for visual detection in situ | |
| CN111579510A (en) | Light sensing film and method for rapidly, quantitatively and selectively detecting Cd (II), Cu (II) and Zn (II) | |
| Muhammad et al. | Determination of mercury (II) in water samples by fluorescence using a dansyl chloride immobilized glass slide | |
| Vu et al. | Electrochemical detection of TNT by differential pulse adsorptive stripping voltammetry at carbon paste electrode modified by 1‐butyl‐3‐methylimidazolium tetrafluoroborate | |
| Zhang et al. | A membrane solid‐phase extraction method based on MIL‐53‐mixed‐matrix membrane for the determination of estrogens and parabens: Polyvinylidene difluoride membrane versus polystyrene‐block‐polybutadiene membrane | |
| CN201926625U (en) | Rapid detection case for detecting harmful substance in traditional Chinese medicine | |
| Acosta et al. | Liquid chromatography coupled to molecular fluorescence with postcolumn UV sensitization for thimerosal and derivative compounds monitoring in environmental samples | |
| CN115015144A (en) | Method for rapidly detecting methyl mercury by carbon dot gold nano enzyme |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |