CN213724351U - Tadalafil oral spray automatic drug delivery device for bioequivalence research - Google Patents
Tadalafil oral spray automatic drug delivery device for bioequivalence research Download PDFInfo
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- CN213724351U CN213724351U CN202022506420.0U CN202022506420U CN213724351U CN 213724351 U CN213724351 U CN 213724351U CN 202022506420 U CN202022506420 U CN 202022506420U CN 213724351 U CN213724351 U CN 213724351U
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- storage cylinder
- drug storage
- drug
- spray
- spray head
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- IEHKWSGCTWLXFU-IIBYNOLFSA-N tadalafil Chemical compound C1=C2OCOC2=CC([C@@H]2C3=C([C]4C=CC=CC4=N3)C[C@H]3N2C(=O)CN(C3=O)C)=C1 IEHKWSGCTWLXFU-IIBYNOLFSA-N 0.000 title claims abstract description 12
- 229960000835 tadalafil Drugs 0.000 title claims abstract description 12
- 229940041678 oral spray Drugs 0.000 title claims description 7
- 239000000668 oral spray Substances 0.000 title claims description 7
- 238000012377 drug delivery Methods 0.000 title claims description 6
- 239000003814 drug Substances 0.000 claims abstract description 122
- 229940079593 drug Drugs 0.000 claims abstract description 72
- 239000007921 spray Substances 0.000 claims abstract description 65
- 238000005507 spraying Methods 0.000 claims abstract description 15
- 238000007789 sealing Methods 0.000 claims abstract description 4
- 239000000428 dust Substances 0.000 claims description 4
- 210000000214 mouth Anatomy 0.000 abstract description 29
- 239000007788 liquid Substances 0.000 abstract description 17
- 210000003928 nasal cavity Anatomy 0.000 description 4
- 239000003292 glue Substances 0.000 description 3
- 239000002699 waste material Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
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Abstract
The utility model relates to the technical field of medical equipment, in particular to an automatic tadalafil mouth spray dosing device for researching bioequivalence, which comprises a drug storage cylinder, wherein a through hole is arranged at the center of one end of the drug storage cylinder, a sealing washer is fixedly arranged in the through hole, a push rod is arranged at one end of the drug storage cylinder, one end of the push rod penetrates through the through hole at the center of one end of the drug storage cylinder and extends into the interior of the drug storage cylinder, a piston is fixedly connected with the end part of one end of the push rod, a through hole is arranged at the upper side of one end of the drug storage cylinder, the automatic dosing device for the mouth spray is arranged in a spray gun type, a spray gun is arranged at one end of the drug storage cylinder, a spray head is arranged at the tail end of the spray gun, the lower end of the spray head is arranged in a flat shape, the upper end of the spray head is arranged in an arc shape, spray holes are arranged at the upper end and two sides of the spray head, the lower end of the spray head has no spray hole, and the spray head only sprays to the upper side and two sides of the oral cavity when spraying, can not be sprayed on the tongue of a patient, and the liquid medicine can continuously act in the oral cavity and can not be swallowed into the body.
Description
Technical Field
The utility model relates to a medical equipment technical field specifically is an automatic device of dosing of tadalafil mouth spray for bioequivalence research.
Background
The bioequivalence test refers to a human test in which the bioavailability is studied, pharmacokinetic parameters are used as indexes, and the degree and speed of absorption of active ingredients are statistically different under the same test conditions by comparing preparations of the same drug in the same or different dosage forms. Present mouth spray all doses through the mode of taking the medicine bottle to spout the medicine in the mouth, this kind of traditional mode of dosing is very convenient, need stretch into the mouth with the medicine bottle mouth, because can not see the position of nozzle, spout wrong position very easily, if not stretch into the mouth, still probably spout in the face or the nasal cavity, give people and bring very big puzzlement, secondly, can directly spout on the tongue when spouting the medicine, if be amazing medicine, can make the people feel very difficult, and most liquid medicine can be taken into patient when swallowing oral liquid in addition, lead to treatment poor, for this reason, the utility model provides an automatic device of dosing of tadalafil mouth spray for bioequivalence research is used for solving above-mentioned problem.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an automatic device of dosing of tadalafil mouth spray for bioequivalence research to solve the problem that provides among the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme: an automatic tadalafil mouth spray dosing device for bioequivalence research comprises a drug storage cylinder, wherein a through hole is formed in the center of one end of the drug storage cylinder, a sealing washer is fixedly installed in the through hole, a push rod is arranged at one end of the drug storage cylinder, one end of the push rod penetrates through the through hole in the center of one end of the drug storage cylinder and extends into the interior of the drug storage cylinder, a piston is fixedly connected with the end part of the push rod, a through hole is formed in the upper side of one end of the drug storage cylinder, a drug feeding hopper is arranged on the upper side of one end of the drug storage cylinder, the lower end of the drug feeding hopper penetrates through the through hole in the upper side of the drug storage cylinder and extends into the interior of the drug storage cylinder, a stop valve is fixedly connected with the middle of the drug feeding hopper, a dust cover is fixedly connected with the top end of the drug feeding hopper, a power supply box is fixedly connected with the upper side of the other end of the drug storage cylinder, a lighting lamp is electrically connected with the power supply box, the tongue depressor is fixedly connected to the lower side of the other end of the medicine storage cylinder, the medicine spraying gun is fixedly connected to the end portion of the other end of the medicine storage cylinder, and the spray head is fixedly connected to the end portion of the other end of the medicine spraying gun.
Preferably, the lower side of the end part of the other end of the tongue depressor is arc-shaped, and the other end of the tongue depressor is positioned below the spray head.
Preferably, the lower end of the spray head is flat, the upper end of the spray head is arc-shaped, and the upper end and the side walls at two sides of the spray head are both provided with a plurality of spray holes.
Preferably, the piston is connected with the inner wall sliding of storage cartridge case, the upper end outer wall of advancing the medicine fill all sets up the screw thread with the inner wall of shield, advance medicine fill and shield inside and outside threaded connection.
Compared with the prior art, the beneficial effects of the utility model are that:
1. the automatic drug delivery device of the oral spray is in a spray gun type, a spray gun is installed at one end of a drug storage cylinder, a spray head is arranged at the tail end of the spray gun, the lower end of the spray head is in a flat plate shape, the upper end of the spray head is in an arc shape, spray holes are formed in the upper end and the two sides of the spray head, the lower end of the spray head is not provided with the spray holes, the spray head only sprays to the upper side and the two sides of an oral cavity when spraying the drug, the drug liquid cannot be sprayed onto the tongue of a patient, the drug liquid can continuously act in the oral cavity, and the drug liquid cannot be swallowed into the body;
2. the lower extreme at storage cartridge case has set up the tongue depressor, when spouting the medicine for patient, the tongue depressor can push down patient's tongue, make the tongue can not glue the liquid medicine, the light has been set up in storage cartridge case's upper end, can throw light on the oral cavity when spouting the medicine, can not spout the wrong position, the shower nozzle is located inside the oral cavity when spouting the medicine in addition, can not spout in face or the nasal cavity, can not waste the liquid medicine, this automatic device simple structure of dosing, high durability and convenient operation, and possible fixed point ration spouts the medicine, alleviate the uncomfortable sense of patient when spouting the medicine.
Drawings
FIG. 1 is a schematic structural view of the automatic drug delivery device of the present invention;
fig. 2 is a schematic view of the structure of the sprinkler head of the present invention.
In the figure: the medicine storage box comprises a medicine storage box 1, a push rod 2, a piston 3, a medicine inlet hopper 4, a stop valve 5, a dustproof cover 6, a power supply box 7, an illuminating lamp 8, a tongue depressor 9, a medicine spraying gun 10, a spray head 11 and a spray hole 12.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1 to 2, the present invention provides a technical solution: an automatic tadalafil mouth spray dosing device for bioequivalence research comprises a drug storage barrel 1, a through hole is arranged at the center of one end of the drug storage barrel 1, a sealing gasket is fixedly arranged in the through hole, a push rod 2 is arranged at one end of the drug storage barrel 1, one end of the push rod 2 penetrates through the through hole at the center of one end of the drug storage barrel 1 and extends into the interior of the drug storage barrel 1, a piston 3 is fixedly connected with one end of the push rod 2, a through hole is arranged at the upper side of one end of the drug storage barrel 1, a drug inlet hopper 4 is arranged at the upper side of one end of the drug storage barrel 1, the lower end of the drug inlet hopper 4 penetrates through the through hole at the upper side of the drug storage barrel 1 and extends into the interior of the drug storage barrel 1, a stop valve 5 is fixedly connected with the middle part of the drug inlet hopper 4, a dust cover 6 is fixedly connected with the top end of the drug inlet hopper 4, the dust cover 6 is opened, the stop valve 5 is opened, liquid medicine is added into the interior of the drug storage barrel 1, a power supply box 7 is fixedly connected with the upper side of the other end of the drug storage barrel 1, one end of power pack 7 is provided with light 8, light 8 and 7 electric connection of power pack, can throw light on the oral cavity when spouting the medicine, can not spout the wrong position, and shower nozzle 11 is located inside the oral cavity when spouting the medicine, can not spout in the face or the nasal cavity, can not waste the liquid medicine, the other end downside fixedly connected with tongue depressor 9 of storage cartridge case 1, when spouting the medicine for patient, tongue depressor 9 can push down patient's tongue, make the tongue can not glue the liquid medicine, the other end tip fixedly connected with of storage cartridge case 1 spouts medicine rifle 10, spout the other end tip fixedly connected with shower nozzle 11 of medicine rifle 10.
Further, the other end tip downside of tongue depressor 9 sets up to the arc, the other end of tongue depressor 9 is located the below of shower nozzle 11, when spouting the medicine for patient, tongue depressor 9 can push down patient's tongue, make the tongue can not glue the liquid medicine, the lower extreme of shower nozzle 11 sets up to flat, the upper end of shower nozzle 11 sets up to circular-arcly, a plurality of orifice 12 has all been seted up to the upper end and the both sides lateral wall of shower nozzle 11, this shower nozzle 11 only can spray to oral cavity upside and both sides when spouting the medicine, can not spout patient's tongue, the liquid medicine can last effect in the oral cavity, can not swallow into internally, piston 3 and the inner wall sliding connection who stores up cartridge case 1, advance the upper end outer wall of medicine fill 4 and the inner wall of shield 6 and all seted up the screw thread, advance medicine fill 4 and the inside and outside threaded connection of shield 6.
The working principle is as follows: when the automatic spraying agent administration device is used, firstly, the dustproof cover 6 is opened, the stop valve 5 is opened, liquid medicine is added into the medicine storage barrel 1, then the stop valve 5 is closed, the dustproof cover 6 is covered, two batteries are installed in the power supply box 7, the illuminating lamp 8 is turned on, the medicine storage barrel 1 is held by hand, the spray head 11 at the tail end of the medicine spraying gun 10 extends into the oral cavity of a patient, the tongue of the patient is pressed by the tongue pressing plate 9, the push rod 2 is pushed, the liquid medicine in the medicine storage barrel 1 is extruded into the medicine spraying gun 10 and then is sprayed into the oral cavity of the patient through the spray head 11, and then the administration device is moved out; the automatic drug delivery device of the mouth spray is arranged in a spray gun type, a drug spray gun 10 is arranged at one end of a drug storage cylinder 1, a spray head 11 is arranged at the tail end of the drug spray gun 10, the lower end of the spray head 11 is arranged in a flat plate shape, the upper end of the spray head 11 is arranged in a circular arc shape, spray holes 12 are formed in the upper end and two sides of the spray head 11, the lower end of the spray head 11 is not provided with the spray holes 12, the spray head 11 only sprays to the upper side and two sides of the oral cavity when spraying drug and cannot spray to the tongue of a patient, the drug liquid can continuously act in the oral cavity and cannot be swallowed into the body, a tongue pressing plate 9 is arranged at the lower end of the drug storage cylinder 1, when spraying drug to the patient, the tongue pressing plate 9 can press the tongue of the patient, so that the tongue cannot be stuck with the drug liquid, an illuminating lamp 8 is arranged at the upper end of the drug storage cylinder 1, the oral cavity can be illuminated when spraying drug, the drug and cannot be sprayed at a wrong position, the spray head 11 is positioned in the oral cavity and cannot be sprayed to the upper side or the nasal cavity, the automatic medicine feeding device has the advantages of simple structure, convenient operation, fixed-point quantitative medicine spraying, and discomfort alleviation when a patient sprays medicine.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (4)
1. A tadalafil oral spray automatic drug delivery device for bioequivalence studies comprising a cartridge (1) characterized by: the drug storage device is characterized in that a through hole is formed in the center of one end of the drug storage cylinder (1), a sealing washer is fixedly mounted in the through hole, a push rod (2) is arranged at one end of the drug storage cylinder (1), one end of the push rod (2) penetrates through the through hole in the center of one end of the drug storage cylinder (1) and extends into the drug storage cylinder (1), a piston (3) is fixedly connected to the end portion of one end of the push rod (2), a through hole is formed in the upside of one end of the drug storage cylinder (1), a drug inlet hopper (4) is arranged on the upside of one end of the drug storage cylinder (1), the lower end of the drug inlet hopper (4) penetrates through the through hole in the upside of the drug storage cylinder (1) and extends into the drug storage cylinder (1), a stop valve (5) is fixedly connected to the middle of the drug inlet hopper (4), a dust cover (6) is fixedly connected to the top end of the drug inlet hopper (4), and a power supply box (7) is fixedly connected to the upside of the other end of the drug storage cylinder (1), the novel drug spraying device is characterized in that an illuminating lamp (8) is arranged at one end of the power supply box (7), the illuminating lamp (8) is electrically connected with the power supply box (7), a tongue depressor (9) is fixedly connected to the lower side of the other end of the drug storage cylinder (1), a drug spraying gun (10) is fixedly connected to the end portion of the other end of the drug storage cylinder (1), and a spray head (11) is fixedly connected to the end portion of the other end of the drug spraying gun (10).
2. The automated tadalafil oral spray delivery device of claim 1, wherein: the lower side of the end part of the other end of the tongue depressor (9) is arc-shaped, and the other end of the tongue depressor (9) is positioned below the spray head (11).
3. The automated tadalafil oral spray delivery device of claim 1, wherein: the lower end of the spray head (11) is flat, the upper end of the spray head (11) is arc-shaped, and the upper end and the side walls on two sides of the spray head (11) are provided with a plurality of spray holes (12).
4. The automated tadalafil oral spray delivery device of claim 1, wherein: piston (3) and the inner wall sliding connection who stores up cartridge case (1), the upper end outer wall of advancing medicine fill (4) and the inner wall of shield (6) all seted up the screw thread, advance medicine fill (4) and shield (6) internal and external threaded connection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022506420.0U CN213724351U (en) | 2020-11-03 | 2020-11-03 | Tadalafil oral spray automatic drug delivery device for bioequivalence research |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022506420.0U CN213724351U (en) | 2020-11-03 | 2020-11-03 | Tadalafil oral spray automatic drug delivery device for bioequivalence research |
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| Publication Number | Publication Date |
|---|---|
| CN213724351U true CN213724351U (en) | 2021-07-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022506420.0U Active CN213724351U (en) | 2020-11-03 | 2020-11-03 | Tadalafil oral spray automatic drug delivery device for bioequivalence research |
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| CN (1) | CN213724351U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114588509A (en) * | 2022-03-14 | 2022-06-07 | 云南根之然生物科技有限公司 | Oral administration device, adaptation composition and composition application thereof |
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2020
- 2020-11-03 CN CN202022506420.0U patent/CN213724351U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114588509A (en) * | 2022-03-14 | 2022-06-07 | 云南根之然生物科技有限公司 | Oral administration device, adaptation composition and composition application thereof |
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: An automatic dosing device for tadalafil oral spray for bioequivalence studies Granted publication date: 20210720 Pledgee: Bank of China Limited Wuhan Hanyang sub branch Pledgor: Wuhan Bereheng Pharmaceutical Technology Co.,Ltd. Registration number: Y2024980022569 |