CN213669884U - Centrifugal device for preparation of cetrorelix - Google Patents
Centrifugal device for preparation of cetrorelix Download PDFInfo
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- CN213669884U CN213669884U CN202022247456.1U CN202022247456U CN213669884U CN 213669884 U CN213669884 U CN 213669884U CN 202022247456 U CN202022247456 U CN 202022247456U CN 213669884 U CN213669884 U CN 213669884U
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Abstract
The utility model discloses a centrifugal device for preparation of cetrorelix, a driving motor is arranged at the lower end of a device mounting frame and is connected with a main driving gear through a motor shaft, the main driving gear is meshed with an auxiliary driving gear, the auxiliary driving gear is connected on a ball screw component through threads, and the top end of the ball screw component is fixedly connected with a centrifugal cavity; the outer cavity component is a cylinder with an open upper end and a closed lower end, and the outer cavity component is positioned outside the inner cavity component. The main driving gear drives the auxiliary driving gear and the screw rod on the ball screw assembly to rotate, the screw rod drives the centrifugal cavity at the top end to rotate, the screw rod is lifted relative to the device mounting frame under the action of threads while the centrifugal cavity rotates, so that the centrifugal cavity is lifted while rotating, overweight and weightless states are added for a medicine principle while centrifuging, and different centrifugal rates and different centrifugal states are adopted for medicine raw materials with different particle sizes.
Description
Technical Field
The utility model relates to a centrifugal device technical field especially relates to a centrifugal device for preparation of cetrorelix.
Background
The cetrorelix is an LHRH antagonist developed by Asta Medica company in Germany, can control the stimulation effect of ovaries, prevent premature follicle from discharging early and help to be pregnant, and a large number of researches show that the cetrorelix has better curative effect on diseases such as ovarian cancer, prostatic cancer, uterine fibroid, endometriosis and the like, and has prevention and improvement effect on benign prostatic hypertrophy and ovarian hyperstimulation syndrome.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a centrifugal device for preparation of cetrorelix, main drive gear drives the screw rod rotation on auxiliary drive gear and the ball subassembly, then the screw rod drives the centrifugal cavity rotation on top, in the rotatory time of centrifugal cavity, the screw rod is relative device mounting bracket lift under the screw thread effect, thereby make centrifugal cavity go up and down in rotatory time, be the additional overweight and weightless state of medicine principle when recentrifugal again, to the medicine raw materials of different particle diameters, adopt different centrifugal speed and different centrifugal state, improve centrifugal efficiency and centrifugal quality, the problem among the prior art has been solved.
In order to achieve the above object, the utility model provides a following technical scheme: a centrifugal device for preparation of cetrorelix comprises a device mounting frame, a centrifugal driving mechanism and a centrifugal cavity, wherein the centrifugal driving mechanism is mounted on the device mounting frame and is connected with the centrifugal cavity through the centrifugal driving mechanism;
the centrifugal driving mechanism comprises a driving motor, a main driving gear, an auxiliary driving gear and a ball screw assembly, wherein the driving motor is arranged at the lower end of the device mounting frame and is connected with the main driving gear through a motor shaft;
the centrifugal cavity comprises an outer cavity component and an inner cavity component, the outer cavity component is a cylinder with an open upper end and a closed lower end, the outer cavity component is positioned outside the inner cavity component, and the lower end face of the inner cavity component is fixedly connected to the lower bottom face of the outer cavity component;
the inner cavity assembly comprises a bottom barrel, a middle barrel and an upper end cover, wherein at least one middle barrel is connected between the bottom barrel and the upper end cover in a locking mode through threads, and centrifugal holes with two through ends are formed in the side walls of the bottom barrel and the middle barrel.
Preferably, the ball screw assembly is composed of a screw rod, a nut and a bearing, the screw rod is rotatably connected with the nut through threads, and the nut is rotatably connected with the device mounting frame through the bearing.
Preferably, the bottom barrel is a barrel with an upper end open and a lower end closed, the edge of the upper end of the barrel is provided with threads, and the middle barrel is connected with the bottom barrel in a locking manner through the threads.
Preferably, the middle cylinder is a cylinder body with two open ends, the upper end of the cylinder body is connected with an upper end cover through thread locking, and the lower end of the cylinder body is connected with a bottom cylinder through thread locking.
Preferably, the upper end cover is in a horn shape with a narrow upper part and a wide lower part, and two through ends.
Compared with the prior art, the beneficial effects of the utility model are as follows:
the utility model discloses a centrifugal device for preparation of cetrorelix, it is rotatory to drive main drive gear through driving motor, main drive gear drives the screw rod rotation on vice drive gear and the ball screw subassembly, then the screw rod drives the centrifugal cavity rotation on top, in the rotatory while of centrifugal cavity, the screw rod goes up and down relative to the device mounting bracket under the screw thread effect, thereby make the centrifugal cavity go up and down in rotatory while, for the additional overweight and weightless state of medicine principle in the time of recentrifugation, to the medicine raw materials of different particle diameters, adopt different centrifugation speed and different centrifugal state, improve centrifugal efficiency and centrifugal quality; a centrifugal cavity with a closed upper end is used as a centrifugal container, and the volume of the centrifugal cavity can be adjusted by setting the number of the middle cylinders; after the centrifugal cavity rotates, the raw materials in the centrifugal cavity overflow from the centrifugal holes in the side wall and enter the outer cavity assembly, and the raw materials with large mass still stay in the inner cavity assembly, so that the layering of the raw materials of the medicine is realized, the treatment process after centrifugation is simplified, and the centrifugation period is shortened; the auxiliary driving gear is fixedly connected with a bearing, and the bearing is limited on the device mounting frame, so that the stability of the gear driving part is improved.
Drawings
FIG. 1 is an overall structure diagram of the present invention;
FIG. 2 is a structural diagram of the centrifugal driving mechanism of the present invention;
FIG. 3 is a diagram of the structure of the centrifugal chamber of the present invention;
fig. 4 is a structural diagram of the inner cavity assembly of the present invention.
In the figure: 1. a device mounting frame; 2. a centrifugal drive mechanism; 21. a drive motor; 22. a main drive gear; 23. a counter drive gear; 24. a ball screw assembly; 3. a centrifugal chamber; 31. an outer cavity assembly; 32. an inner chamber component; 321. a bottom cylinder; 322. a middle cylinder; 323. an upper end cover; 324. and (4) centrifugal holes.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1-4, a centrifugal device for cetrorelix preparation comprises a device mounting frame 1, a centrifugal driving mechanism 2 and a centrifugal cavity 3, wherein the centrifugal driving mechanism 2 is mounted on the device mounting frame 1, and is connected with the centrifugal cavity 3 through the centrifugal driving mechanism 2;
the centrifugal driving mechanism 2 comprises a driving motor 21, a main driving gear 22, an auxiliary driving gear 23 and a ball screw assembly 24, wherein the driving motor 21 is installed at the lower end of the device installation frame 1 and is connected with the main driving gear 22 through a motor shaft, the main driving gear 22 is meshed with the auxiliary driving gear 23, so that the force on the main driving gear 22 can be transmitted to the auxiliary driving gear 23, the auxiliary driving gear 23 is connected to the ball screw assembly 24 through threads, the ball screw assembly 24 is composed of a screw rod, a nut and a bearing, the screw rod is rotatably connected with the nut through threads, the nut is rotatably connected with the device installation frame 1 through the bearing, and the top end of the ball screw assembly 24 is fixedly;
the centrifugal cavity 3 comprises an outer cavity component 31 and an inner cavity component 32, the outer cavity component 31 is a cylinder with an open upper end and a closed lower end, the outer cavity component 31 is positioned outside the inner cavity component 32, and the lower end surface of the inner cavity component 32 is fixedly connected to the lower bottom surface of the outer cavity component 31;
the inner cavity assembly 32 comprises a bottom barrel 321, a middle barrel 322 and an upper end cover 323, at least one middle barrel 322 is connected between the bottom barrel 321 and the upper end cover 323 through screw thread locking, centrifugal holes 324 with two through ends are respectively arranged on the side walls of the bottom barrel 321 and the middle barrel 322, the bottom barrel 321 is a barrel with an upper end open and a lower end closed, the upper end edge of the barrel is provided with screw threads, the middle barrel 322 is connected through screw thread locking, the middle barrel 322 is a barrel with two through ends, the upper end of the barrel is connected with the upper end cover 323 through screw thread locking, the upper end cover 323 is in a horn shape with two through ends, the lower end is connected with the bottom barrel 321 through screw thread locking, the main driving gear 22 is driven by the driving motor 21 to rotate, the main driving gear 22 drives the auxiliary driving gear 23 and the screw rod on the ball screw assembly 24 to rotate, the screw rod drives the centrifugal cavity 3 at the top end to, the screw rod is lifted relative to the device mounting frame 1 under the action of the threads, so that the centrifugal cavity 3 is lifted while rotating, overweight and weightlessness states are added for the medicine principle while centrifuging, and different centrifugal rates and different centrifugal states are adopted for medicine raw materials with different particle sizes, so that the centrifugal efficiency and the centrifugal quality are improved; the centrifugal cavity 3 with the upper end closed is used as a centrifugal container, and the volume of the centrifugal cavity 3 can be adjusted by setting the number of the middle cylinders 322; after the centrifugal cavity 3 rotates, the raw materials in the centrifugal cavity overflow from the centrifugal holes 324 on the side wall and enter the outer cavity component 31, and the raw materials with large mass still stay in the inner cavity component 32, so that the layering of the raw materials of the medicine is realized, the processing procedure after centrifugation is simplified, and the centrifugation period is shortened; the counter drive gear 23 is fixedly connected with a bearing, and the bearing is limited on the device mounting frame 1, so that the stability of the counter drive gear 23 is enhanced.
The working principle is as follows: the driving motor 21 drives the main driving gear 22 to rotate, the main driving gear 22 drives the auxiliary driving gear 23 and the screw rod on the ball screw assembly 24 to rotate, the screw rod drives the centrifugal cavity 3 at the top end to rotate, the screw rod is lifted relative to the device mounting frame 1 under the action of threads while the centrifugal cavity 3 rotates, so that the centrifugal cavity 3 is lifted while rotating, overweight and weightlessness states are added to the medicine principle while centrifuging, different centrifugation rates and different centrifugation states are adopted for medicine raw materials with different particle sizes, the centrifugal cavity 3 with the upper end closed up is used as a centrifugal container, and the volume of the centrifugal cavity 3 can be adjusted through the number of the middle cylinders 322; after the centrifugal cavity 3 rotates, the raw materials inside the centrifugal cavity overflow from the centrifugal holes 324 on the side wall and enter the outer cavity assembly 31, and the raw materials with large mass still stay in the inner cavity assembly 32, so that the layering of the medicine raw materials is realized.
In summary, the following steps: the utility model discloses a centrifugal device for preparation of cetrorelix, install centrifugal actuating mechanism 2 on the device mounting bracket 1, and be connected with centrifugal cavity 3 through centrifugal actuating mechanism 2, driving motor 21 is installed in the lower extreme of device mounting bracket 1, and be connected with main drive gear 22 through the motor shaft, main drive gear 22 and auxiliary drive gear 23 intermeshing, make the power on the main drive gear 22 can conduct on auxiliary drive gear 23, auxiliary drive gear 23 is connected on ball screw assembly 24 through the screw thread, ball screw assembly 24 comprises screw rod, nut and bearing, there is the nut on the screw rod through the rotatory nut that is connected with of screw thread, the nut passes through bearing swivelling joint device mounting bracket 1, ball screw assembly 24's top fixedly connected with centrifugal cavity 3, outer cavity subassembly 31 is the barrel that the upper end is uncovered lower extreme confined, and outer cavity subassembly 31 is located the outside of interior cavity subassembly 32, the lower end face of the inner cavity component 32 is fixedly connected to the lower bottom face of the outer cavity component 31, at least one middle cylinder 322 is connected between the bottom cylinder 321 and the upper end cover 323 through screw thread locking, centrifugal holes 324 with two through ends are respectively arranged on the side walls of the bottom cylinder 321 and the middle cylinder 322, the bottom cylinder 321 is a cylinder with an upper end open and a lower end closed, the upper end edge of the cylinder is provided with screw thread, the middle cylinder 322 is connected through screw thread locking, the middle cylinder 322 is a cylinder with two through ends open, the upper end of the cylinder is connected with the upper end cover 323 through screw thread locking, the upper end cover 323 is in a horn shape with two through ends, the lower end is connected with the bottom cylinder 321 through screw thread locking, the main driving gear 22 is driven to rotate by the driving motor 21, the main driving gear 22 drives the auxiliary driving gear 23 and the screw rod on the ball screw assembly 24 to rotate, the screw rod drives the centrifugal cavity 3 at, the screw rod is lifted relative to the device mounting frame 1 under the action of the threads, so that the centrifugal cavity 3 is lifted while rotating, overweight and weightlessness states are added for the medicine principle while centrifuging, and different centrifugal rates and different centrifugal states are adopted for medicine raw materials with different particle sizes, so that the centrifugal efficiency and the centrifugal quality are improved; the centrifugal cavity 3 with the upper end closed is used as a centrifugal container, and the volume of the centrifugal cavity 3 can be adjusted by setting the number of the middle cylinders 322; after the centrifugal cavity 3 rotates, the raw materials inside the centrifugal cavity overflow from the centrifugal holes 324 on the side wall and enter the outer cavity component 31, and the raw materials with large mass still stay in the inner cavity component 32, so that the layering of the raw materials of the medicine is realized, the processing procedure after centrifugation is simplified, and the centrifugation period is shortened.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (5)
1. A centrifugal device for preparation of cetrorelix, includes device mounting bracket (1), centrifugal actuating mechanism (2) and centrifugal cavity (3), its characterized in that: a centrifugal driving mechanism (2) is arranged on the device mounting frame (1), and a centrifugal cavity (3) is connected through the centrifugal driving mechanism (2);
the centrifugal driving mechanism (2) comprises a driving motor (21), a main driving gear (22), an auxiliary driving gear (23) and a ball screw assembly (24), the driving motor (21) is installed at the lower end of the device installation frame (1) and is connected with the main driving gear (22) through a motor shaft, the main driving gear (22) is meshed with the auxiliary driving gear (23), the auxiliary driving gear (23) is connected to the ball screw assembly (24) through threads, and the top end of the ball screw assembly (24) is fixedly connected with a centrifugal cavity (3);
the centrifugal cavity (3) comprises an outer cavity component (31) and an inner cavity component (32), the outer cavity component (31) is a cylinder with an open upper end and a closed lower end, the outer cavity component (31) is positioned outside the inner cavity component (32), and the lower end face of the inner cavity component (32) is fixedly connected to the lower bottom face of the outer cavity component (31);
the inner cavity assembly (32) comprises a bottom barrel (321), a middle barrel (322) and an upper end cover (323), wherein at least one middle barrel (322) is connected between the bottom barrel (321) and the upper end cover (323) in a locking mode through threads, and centrifugal holes (324) with two through ends are formed in the side walls of the bottom barrel (321) and the middle barrel (322).
2. The centrifuge device for cetrorelix preparation according to claim 1, wherein: the ball screw assembly (24) is composed of a screw rod, a nut and a bearing, the screw rod is connected with the nut in a rotating mode through threads, and the nut is connected with the device mounting frame (1) in a rotating mode through the bearing.
3. The centrifuge device for cetrorelix preparation according to claim 1, wherein: the bottom barrel (321) is a barrel with an upper end open and a lower end closed, the edge of the upper end of the barrel is provided with threads, and the middle barrel (322) is connected with the upper end of the barrel in a locking mode through the threads.
4. The centrifuge device for cetrorelix preparation according to claim 1, wherein: the middle barrel (322) is a barrel with two open ends, the upper end of the barrel is connected with an upper end cover (323) through thread locking, and the lower end of the barrel is connected with a bottom barrel (321) through thread locking.
5. The centrifuge device for cetrorelix preparation according to claim 1, wherein: the upper end cover (323) is in a horn shape with narrow top and wide bottom and two through ends.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022247456.1U CN213669884U (en) | 2020-10-12 | 2020-10-12 | Centrifugal device for preparation of cetrorelix |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022247456.1U CN213669884U (en) | 2020-10-12 | 2020-10-12 | Centrifugal device for preparation of cetrorelix |
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| Publication Number | Publication Date |
|---|---|
| CN213669884U true CN213669884U (en) | 2021-07-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202022247456.1U Active CN213669884U (en) | 2020-10-12 | 2020-10-12 | Centrifugal device for preparation of cetrorelix |
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| Country | Link |
|---|---|
| CN (1) | CN213669884U (en) |
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- 2020-10-12 CN CN202022247456.1U patent/CN213669884U/en active Active
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