CN213669074U - Raw material mixing device for darunavir intermediate - Google Patents

Raw material mixing device for darunavir intermediate Download PDF

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Publication number
CN213669074U
CN213669074U CN202022001869.1U CN202022001869U CN213669074U CN 213669074 U CN213669074 U CN 213669074U CN 202022001869 U CN202022001869 U CN 202022001869U CN 213669074 U CN213669074 U CN 213669074U
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China
Prior art keywords
barrel body
motor
compression roller
raw material
filter screen
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CN202022001869.1U
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Chinese (zh)
Inventor
张国良
袁晓波
杨永生
贾云峰
高福元
康中华
韩潘
陈茂春
陈松
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Sichuan Jiuling Pharmaceutical Technology Co ltd
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Sichuan Jiuling Pharmaceutical Technology Co ltd
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Abstract

The utility model discloses a raw material mixing device for a darunavir intermediate body, which comprises a barrel body, wherein the upper end of the barrel body is communicated with a feed inlet, the inner wall of the barrel body is respectively and fixedly provided with a first filter screen and a second filter screen, the interior of the barrel body is respectively and rotatably provided with a first compression roller and a second compression roller, the first compression roller is positioned at the upper end of the first filter screen, the second compression roller is positioned at the upper end of the second filter screen, the bottom of the barrel body is fixedly provided with a first motor, one end of an output shaft of the first motor is fixedly connected with a rotating shaft through a shaft coupling, one end of the rotating shaft penetrates through the barrel body and is inserted into the barrel body, and a stirring rod is fixedly arranged on the rotating shaft, the utility model can synchronously grind and dissolve, greatly shortens the working time, lightens the labor pressure of workers, accelerates the speed of mixing raw, the working time is saved.

Description

Raw material mixing device for darunavir intermediate
Technical Field
The utility model relates to a raw materials mixing equipment technical field specifically is a darunavir is raw materials mixing arrangement for intermediate body.
Background
In recent years, as a result of the development of scientific technology, we have discovered a number of viruses not previously known to us and, through the efforts of medical researchers, have finally found a cure for the disease, but many problems remain to be solved, among which one of the effective approaches to the treatment of aids is darunavir, which can be used in combination with ritonavir or other antiretroviral drugs for adult patients infected with HIV1 who have been resistant to more than 1 protease inhibitor who has received antiretroviral drug therapy.
The production of the darunavir intermediate requires mixing the raw materials, but the prior art requires grinding and crushing the raw materials first and then mixing the raw materials, and the mixing speed is slow, the time is long, and the working efficiency is low, so that a raw material mixing device for the darunavir intermediate needs to be provided.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a darunavir is raw materials mixing arrangement for intermediate body can pulverize grinding and stirring dissolve and go on in step, has shortened operating time greatly, has alleviateed staff's labor pressure, makes the speed that the raw materials mixes accelerate, has improved work efficiency, has saved operating time to solve the problem that proposes in the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a darunavir is raw materials mixing arrangement for midbody, includes the staving, the upper end intercommunication of staving has the feed inlet, the inner wall difference fixed mounting of staving has first filter screen and second filter screen, the inside of staving rotates respectively and installs first compression roller and second compression roller, first compression roller is located the upper end of first filter screen, the second compression roller is located the upper end of second filter screen, the bottom fixed mounting of staving has first motor, shaft coupling fixedly connected with pivot is passed through to first motor output shaft one end, the one end of pivot is run through the staving and is pegged graft in the inside of staving, fixed mounting has the puddler in the pivot, the inner wall fixed mounting of staving has the dead lever, dead lever and puddler are crisscross setting, one side intercommunication of staving has the discharge gate.
Preferably, the outer wall of the barrel body is fixedly provided with a second motor and a third motor respectively, one end of an output shaft of the second motor penetrates through the outer wall of the barrel body and is fixedly connected to one end of the first compression roller through a coupler, and one end of an output shaft of the third motor penetrates through the outer wall of the barrel body and is fixedly connected to one end of the second compression roller through a coupler.
Preferably, the first press roller and the second press roller are both provided with first lugs, and the first lugs are arranged in an array.
Preferably, the stirring rods are at least provided with six groups, and the six groups of stirring rods are symmetrically arranged.
Preferably, the stirring rod is provided with second bumps, and the second bumps are arranged in an array.
Preferably, the second bump is provided with spikes, and the spikes are arranged in an array.
Preferably, the bottom of the barrel body is respectively and fixedly provided with a support leg and a motor frame, and the first motor is fixedly arranged inside the motor frame through a fixing frame.
Preferably, the bottom of the barrel body is provided with a through hole, a sealing bearing is fixedly embedded in the through hole, and one end of the rotating shaft is fixedly inserted into an inner ring of the sealing bearing.
Compared with the prior art, the beneficial effects of the utility model are that:
through the design of the first compression roller and the second compression roller, the second motor drives the first compression roller to crush the raw material, the raw material with fine particles falls from the gap of the first filter screen, the raw material which is not crushed falls onto the second filter screen, the third motor drives the second compression roller to crush the raw material again, and the raw material which is finally fine particles enters the stirring mechanism below;
through the design of dead lever, second lug and thorn post, dead lever and puddler are the setting of staggering, can make the solution rate accelerate, because be provided with the second lug on the puddler, be provided with the thorn post on the second lug, the thorn post can pierce the great raw materials of granule, accelerates the dissolution of raw materials, the utility model discloses the speed that makes the raw materials mix accelerates, has improved work efficiency, has saved operating time.
Drawings
Fig. 1 is a schematic view of the internal structure of the present invention;
fig. 2 is a schematic structural diagram of the first pressing roller, the second pressing roller and the first bump of the present invention;
fig. 3 is a schematic structural view of the stirring rod and the second bump of the present invention;
fig. 4 is a schematic structural view of the second bump and the spike of the present invention.
In the figure: 1. a barrel body; 2. a feed inlet; 3. a first press roll; 4. a first filter screen; 5. a second press roll; 6. a second filter screen; 7. a rotating shaft; 8. fixing the rod; 9. a stirring rod; 10. a discharge port; 11. pricking columns; 12. sealing the bearing; 13. a motor frame; 14. a first motor; 15. a support leg; 16. a first bump; 17. a second motor; 18. a third motor; 19. and a second bump.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1-4, the present invention provides a technical solution: a raw material mixing device for a darunavir intermediate body comprises a barrel body 1, wherein the upper end of the barrel body 1 is communicated with a feed inlet 2, raw materials are convenient to add, a first filter screen 4 and a second filter screen 6 are fixedly mounted on two sides of the inner wall of the barrel body 1 respectively, the second filter screen 6 is positioned at the lower end of the first filter screen 4, the first filter screen 4 and the second filter screen 6 are obliquely arranged, the ground raw materials fall down conveniently, a first compression roller 3 and a second compression roller 5 are rotatably mounted in the barrel body 1 respectively, the rotating directions of the first compression roller 3 and the second compression roller 5 face the falling direction of the raw materials, first convex blocks 16 are arranged on the first compression roller 3 and the second compression roller 5 respectively, the first convex blocks 16 are arranged in an array mode, the raw materials are convenient to roll, the rolling speed is increased, and the;
a second motor 17 and a third motor 18 are fixedly installed on the outer wall of the barrel body 1 respectively, one end of an output shaft of the second motor 17 penetrates through the outer wall of the barrel body 1 and is fixedly connected to one end of the first compression roller 3 through a coupler, the second motor 17 drives the first compression roller 3 to rotate, one end of an output shaft of the third motor 18 penetrates through the outer wall of the barrel body 1 and is fixedly connected to one end of the second compression roller 5 through a coupler, the third motor 18 drives the second compression roller 5 to rotate, the first compression roller 3 is located at the upper end of the first filter screen 4, and the second compression roller 5 is located at the upper end of the second filter screen 6, so;
the bottom of the barrel body 1 is fixedly provided with a first motor 14, the bottom of the barrel body 1 is respectively and fixedly provided with a support leg 15 and a motor frame 13, the first motor 14 is fixedly arranged inside the motor frame 13 through a fixing frame, one end of an output shaft of the first motor 14 is fixedly connected with a rotating shaft 7 through a coupler, the bottom of the barrel body 1 is provided with a through hole, a sealing bearing 12 is embedded and fixed in the through hole, one end of the rotating shaft 7 is fixedly inserted into an inner ring of the sealing bearing 12, the first motor 14 drives the rotating shaft 7 to rotate, one end of the rotating shaft 7 penetrates through the barrel body 1 and is inserted into the barrel body 1, a stirring rod 9 is fixedly arranged on the rotating shaft 7, the rotating shaft 7 drives the stirring rod 9 to rotate, at least six groups of stirring rods 9;
be provided with second lug 19 on puddler 9, second lug 19 is the array setting, is provided with thorn post 11 on the second lug 19, and thorn post 11 is the array setting, and usable thorn post 11 will not pulverize the raw materials and carry out the breakage, improves the stirring speed, makes the raw materials dissolve fast, and the inner wall fixed mounting of staving 1 has dead lever 8, and dead lever 8 and puddler 9 are the setting of staggering, and the raw materials of being convenient for dissolve with higher speed, and one side intercommunication of staving 1 has discharge gate 10.
The working principle is as follows: when the device is used, raw materials are poured from a feeding hole and fall on the first filter screen 4 and fall to the lower end of the first press roller 3, the second motor 17 drives the first press roller 3 to crush the raw materials, the fine raw materials fall from gaps of the first filter screen 4, the raw materials which are not crushed fall on the second filter screen 6, the third motor 18 drives the second press roller 5 to crush the raw materials again, and finally the raw materials which are fine particles enter a stirring mechanism below;
start first motor 14, first motor 14 drives pivot 7 and rotates, pivot 7 drives puddler 9 and rotates, because the inner wall fixed mounting of staving 1 has dead lever 8, dead lever 8 and puddler 9 are the setting of staggering, can make dissolving speed accelerate, because be provided with second lug 19 on the puddler 9, be provided with thorn post 11 on the second lug 19, the thorn post can be punctured the great raw materials of granule, with higher speed the dissolving of raw materials, after the stirring is accomplished, open discharge gate 10, collect the raw materials after mixing.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (8)

1. The utility model provides a darunavir is raw materials mixing arrangement for intermediate body, includes staving (1), its characterized in that: the upper end of the barrel body (1) is communicated with a feed inlet (2), the inner wall of the barrel body (1) is respectively and fixedly provided with a first filter screen (4) and a second filter screen (6), the interior of the barrel body (1) is respectively and rotatably provided with a first compression roller (3) and a second compression roller (5), the first compression roller (3) is positioned at the upper end of the first filter screen (4), the second compression roller (5) is positioned at the upper end of the second filter screen (6), the bottom of the barrel body (1) is fixedly provided with a first motor (14), one end of an output shaft of the first motor (14) is fixedly connected with a rotating shaft (7) through a coupler, one end of the rotating shaft (7) penetrates through the barrel body (1) and is inserted into the barrel body (1), a stirring rod (9) is fixedly arranged on the rotating shaft (7), a fixing rod (8) is fixedly arranged on the inner wall of the barrel body (1), and the fixing rod (8) and, one side of the barrel body (1) is communicated with a discharge hole (10).
2. The raw material mixing device for the darunavir intermediate as claimed in claim 1, wherein: the outer wall of staving (1) is fixed mounting respectively has second motor (17) and third motor (18), the outer wall that second motor (17) output shaft one end runs through staving (1) passes through the one end of shaft coupling fixed connection in first compression roller (3), the outer wall that third motor (18) output shaft one end runs through staving (1) passes through the one end of shaft coupling fixed connection in second compression roller (5).
3. The raw material mixing device for the darunavir intermediate as claimed in claim 1, wherein: first protruding blocks (16) are arranged on the first pressing roller (3) and the second pressing roller (5), and the first protruding blocks (16) are arranged in an array mode.
4. The raw material mixing device for the darunavir intermediate as claimed in claim 1, wherein: the stirring rods (9) are at least provided with six groups, and the six groups of stirring rods (9) are symmetrically arranged.
5. The raw material mixing device for the darunavir intermediate as claimed in claim 1, wherein: the stirring rod (9) is provided with second convex blocks (19), and the second convex blocks (19) are arranged in an array.
6. The raw material mixing device for the darunavir intermediate as claimed in claim 5, wherein: the second bump (19) is provided with barbed posts (11), and the barbed posts (11) are arranged in an array.
7. The raw material mixing device for the darunavir intermediate as claimed in claim 5, wherein: the bottom of staving (1) is fixed mounting respectively has landing leg (15) and motor frame (13), first motor (14) are through fixed frame fixed mounting in the inside of motor frame (13).
8. The raw material mixing device for the darunavir intermediate as claimed in claim 5, wherein: the bottom of the barrel body (1) is provided with a through hole, a sealing bearing (12) is fixedly embedded in the through hole, and one end of the rotating shaft (7) is fixedly inserted into an inner ring of the sealing bearing (12).
CN202022001869.1U 2020-09-14 2020-09-14 Raw material mixing device for darunavir intermediate Active CN213669074U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202022001869.1U CN213669074U (en) 2020-09-14 2020-09-14 Raw material mixing device for darunavir intermediate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202022001869.1U CN213669074U (en) 2020-09-14 2020-09-14 Raw material mixing device for darunavir intermediate

Publications (1)

Publication Number Publication Date
CN213669074U true CN213669074U (en) 2021-07-13

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CN (1) CN213669074U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114917798A (en) * 2022-05-27 2022-08-19 安徽华谊日新科技有限公司 Device for producing and mixing offset printing ink with enhanced homogenization degree and application method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114917798A (en) * 2022-05-27 2022-08-19 安徽华谊日新科技有限公司 Device for producing and mixing offset printing ink with enhanced homogenization degree and application method thereof

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