CN213567231U

CN213567231U - alpha-L-fucosidase detection kit capable of overcoming test solution residue

Info

Publication number: CN213567231U
Application number: CN202021119820.XU
Authority: CN
Inventors: 戴震; 左颖; 谢超; 马四桃; 门姝
Original assignee: Xinjiang Kanasi Biotechnology Co ltd
Current assignee: Xinjiang Kanasi Biotechnology Co ltd
Priority date: 2020-06-17
Filing date: 2020-06-17
Publication date: 2021-06-29
Anticipated expiration: 2030-06-17

Abstract

The utility model discloses an alpha-L-fucosidase detection kit capable of overcoming test solution residue, which comprises a box body, wherein the inner wall of the box body is fixedly connected with a second supporting plate, a first supporting plate and a first rubber pad from top to bottom in sequence, the bottom of the first rubber pad is fixedly connected with the inner wall of the bottom of the box body, a plurality of limiting holes are uniformly arranged at the top of the second supporting plate in a penetrating manner, and a plurality of reagent bottles are arranged inside the box body; the utility model discloses a set up reagent bottle, converge the groove, get the liquid pipe, the lid, standing groove etc. place the reagent bottle in the standing groove at lid top, and when making the opening of getting the liquid pipe upwards perpendicularly, the geometric axis line of reagent pipe can keep being parallel with the top surface of lid, thereby make remaining test solution in the reagent bottle along the slope interior wall flow of reagent bottle to converge the inslot, so that take remaining test solution, the test solution in the reagent bottle that has significantly reduced is remained, the waste to the test solution has been reduced.

Description

alpha-L-fucosidase detection kit capable of overcoming test solution residue

Technical Field

The utility model relates to a kit, in particular to an alpha-L-fucosidase detection kit capable of overcoming the residue of a test solution.

Background

alpha-L-Fucosidase (AFU) is a lysosomal enzyme, and its systematic name is alpha-L-Fucosidase (EC3.2.1.51). The basic physiological function of AFU is to participate in the catabolism of various glycolipids and glycoproteins containing fucosyl groups. Genetic AFU deficiency can cause fucoside storage disease, which can be diagnosed and identified by AFU determination in tissue cells, urine and serum. The activity of serum AFU of a patient with primary liver cancer (PHC) is obviously higher than that of a healthy person, and is also obviously higher than that of metastatic liver cancer, cholangiocellular carcinoma, malignant vascular endothelial cell tumor, malignant mesothelioma, liver cirrhosis, congenital hepatic cyst and other benign liver space occupying lesions. Generally, the sensitivity of AFU is higher than that of AFP, the specificity is worse than that of AFP, and the detection rate of liver cancer can be improved by the combined monitoring of AFU and AFP.

The existing alpha-L-fucosidase detection kit has the advantages that most of containers used for storing reagents are cylindrical, a small amount of test solution is remained and adhered to the inner wall surface of the container under the action of surface tension in the process of taking out the reagents, and meanwhile, a certain amount of test solution cannot be taken out of the container due to the fact that a suction nozzle of a solution taking tool is usually short and cannot touch the bottom of the container, so that the waste of the test solution is caused, and the cylindrical container is easy to roll after being carelessly knocked over, so that the test solution is broken and needs to be improved.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a can overcome remaining alpha-L-fucosidase detect kit of test solution to solve the problem that proposes among the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme:

an alpha-L-fucosidase detection kit capable of overcoming test solution residue comprises a kit body, wherein a second supporting plate, a first supporting plate and a first rubber pad are fixedly connected to the inner wall of the kit body from top to bottom in sequence, the bottom of the first rubber pad is fixedly connected with the inner wall of the bottom of the kit body, a plurality of limiting holes are uniformly arranged at the top of the second supporting plate in a penetrating manner, a plurality of reagent bottles are arranged in the kit body and are positioned in the corresponding limiting holes, the bottom ends of the reagent bottles penetrate through the top of the first supporting plate and are attached to the top of the first rubber pad, a converging groove protruding outwards is arranged at the top of the outer wall of each reagent bottle, a liquid taking pipe is arranged at the symmetrical position of the outer wall of each reagent bottle and the converging groove in a penetrating manner, a sealing cover is connected to the outer wall of the liquid taking pipe in a threaded fit manner, the box body is fixedly connected with the box cover through a hasp, and a plurality of placing grooves are formed in the top of the box cover.

As a further aspect of the present invention: the appearance of the reagent bottle is frustum-shaped, two opposite side walls of the confluence groove are tangent to the circumferential outer wall of the reagent bottle, the confluence groove is obliquely arranged with the outer wall opposite to the top of the reagent bottle, and the included angle between the outer wall and the circumferential outer wall of the reagent bottle is 100-120 degrees.

As a further aspect of the present invention: reagent bottle, groove of converging, liquid intaking pipe are integrated into one piece structure, reagent bottle, groove of converging, liquid intaking pipe, sealed lid all are located spacing downthehole, the inner wall in spacing hole and reagent bottle, converge groove, liquid intaking pipe, the whole outer wall of sealed lid laminate mutually.

As a further aspect of the present invention: the reagent bottle cover is characterized in that a plurality of springs are uniformly and fixedly connected to the inner wall of the top of the box cover, a plurality of springs are fixedly connected to the bottom of the pressing plate, a second rubber pad is arranged at the bottom of the pressing plate, and the bottoms of the second rubber pads are attached to the tops of a plurality of reagent bottles.

As a further aspect of the present invention: the shape and size of the placing groove are matched with the shape and size of an assembly formed by the reagent bottle and the confluence groove.

Compared with the prior art, the beneficial effects of the utility model are that:

1. the utility model discloses a set up reagent bottle, converge the groove, get the liquid pipe, the lid, standing groove etc. place the reagent bottle in the standing groove at lid top, and when making the opening of getting the liquid pipe upwards perpendicularly, the geometric axis line of reagent pipe can keep being parallel with the top surface of lid, thereby make remaining test solution in the reagent bottle along the slope interior wall flow of reagent bottle to converge the inslot, so that take remaining test solution, the test solution in the reagent bottle that has significantly reduced is remained, the waste to the test solution has been reduced.

2. The utility model discloses a circumference outer wall at frustum body reagent bottle sets up groove and liquid taking pipe of converging, when the reagent bottle is knocked down by carelessness, can effectively avoid the reagent bottle to roll at the operation panel surface, excellent in use effect.

3. The utility model discloses a set up spring, clamp plate, first rubber pad, second rubber pad, when the lid was closed, the elasticity of usable spring passed through the clamp plate and compressed tightly the second rubber pad downwards to utilize second rubber pad and first rubber pad to carry out good fixed to the reagent bottle, first backup pad, second backup pad can prevent effectively that the reagent bottle from taking place to rock and collide in the box body simultaneously, thereby play good guard action.

Drawings

FIG. 1 is a schematic structural diagram of an alpha-L-fucosidase assay kit capable of overcoming sample solution residue.

FIG. 2 is a schematic structural diagram of a limiting hole in an alpha-L-fucosidase assay kit capable of overcoming sample solution residue.

FIG. 3 is a schematic structural diagram of a holding tank in an alpha-L-fucosidase assay kit capable of overcoming the residue of a test solution.

FIG. 4 is a schematic structural diagram of a reagent bottle in an alpha-L-fucosidase assay kit capable of overcoming the residue of a test solution.

Wherein, box body 1, first rubber pad 2, first backup pad 3, second backup pad 4, spacing hole 5, lid 6, standing groove 7, spring 8, clamp plate 9, second rubber pad 10, reagent bottle 11, converge groove 12, get liquid pipe 13, sealed lid 14.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-4, in the embodiment of the present invention, an α -L-fucosidase assay kit capable of overcoming a sample solution residue comprises a kit body 1, a second supporting plate 4, a first supporting plate 3, and a first rubber pad 2 are fixedly connected to an inner wall of the kit body 1 from top to bottom, a plurality of limiting holes 5 are uniformly formed through a top of the second supporting plate 4, a plurality of reagent bottles 11 are disposed inside the kit body 1, the reagent bottles 11 are disposed in the corresponding limiting holes 5, a bottom end of each reagent bottle 11 penetrates through a top of the first supporting plate 3 and then is attached to a top of the first rubber pad 2, a collecting groove 12 protruding outward is disposed on a top of an outer wall of each reagent bottle 11, a liquid taking tube 13 is disposed at a symmetrical position of the outer wall of each reagent bottle 11 and the collecting groove 12, and a sealing cover 14 is connected to an outer wall of the liquid taking tube 13 through a screw thread fit, the top of box body 1 is provided with lid 6, and box body 1 passes through hasp fixed connection with lid 6, and a plurality of standing grooves 7 have been seted up at the top of lid 6.

The appearance of reagent bottle 11 is the frustum type, and two relative lateral walls of converging groove 12 are tangent with the circumference outer wall of reagent bottle 11, and converging groove 12 is the slope setting with the relative outer wall in top of reagent bottle 11, and the contained angle of this outer wall and the circumference outer wall of reagent bottle 11 is 100 ~ 120.

Reagent bottle 11, groove 12 that converges, liquid taking pipe 13 are integrated into one piece structure, and reagent bottle 11, groove 12 that converges, liquid taking pipe 13, sealed lid 14 all are located spacing hole 5, and the inner wall of spacing hole 5 and reagent bottle 11, groove 12 that converges, liquid taking pipe 13, the whole outer wall of sealed lid 14 are laminated mutually.

The even fixedly connected with a plurality of springs 8 of top inner wall of lid 6, the common fixedly connected with clamp plate 9 in bottom of a plurality of springs 8, the bottom of clamp plate 9 is provided with second rubber pad 10, and the bottom of second rubber pad 10 is laminated each other with the top of a plurality of reagent bottles 11.

The shape and size of the placing groove 7 are matched with the shape and size of the combined body formed by the reagent bottle 11 and the confluence groove 12.

The utility model discloses a theory of operation is:

the utility model discloses a set up converging groove 12 at the reagent bottle 11 outer wall of frustum type, when placing reagent bottle 11 in the standing groove 7 at lid 6 top, and make the opening of liquid taking pipe 13 upwards perpendicularly, at this moment, the geometric axis line of reagent bottle 11 will keep parallel with the top surface of lid 6, thus make the test solution in reagent bottle 11 flow to converging groove 12 along the slope inner wall of reagent bottle 11, later insert needle tubing or other liquid taking tool in converging groove 12 from liquid taking pipe 13, can take the test solution in reagent bottle 11, when the surplus test solution volume in reagent bottle 11 is less, surplus test solution also will flow into converging groove 12 along the slope inner wall of reagent bottle 11, because the opening part of liquid taking pipe 13 and the spacing distance of converging groove 12 bottom are far less than the height of reagent bottle 11, therefore the suction nozzle of liquid taking tool can directly contact with the bottom of converging groove 12, thereby the surplus test solution is taken, the residual of the test solution in the reagent bottle 11 is greatly reduced, and the waste of the test solution is reduced.

Through the setting of converging groove 12 and liquid-taking pipe 13, when reagent bottle 11 is knocked over by accident, can effectively avoid reagent bottle 11 to roll on the operation panel surface.

The utility model discloses a set up spring 8, clamp plate 9, first rubber pad 2, second rubber pad 10, when lid 6 was closed, usable spring 8's elasticity passed through clamp plate 9 and compresses tightly second rubber pad 10 downwards to utilize second rubber pad 10 and first rubber pad 2 to carry out good fixed to reagent bottle 11, first backup pad 3, second backup pad 4 can prevent effectively that reagent bottle 11 from taking place to rock in box body 1 simultaneously, thereby play good guard action.

Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.

Claims

1. The utility model provides an alpha-L-fucosidase assay kit that can overcome test solution is remaining, includes box body (1), its characterized in that: the inner wall of the box body (1) is fixedly connected with a second supporting plate (4), a first supporting plate (3) and a first rubber pad (2) from top to bottom in sequence, the bottom of the first rubber pad (2) is fixedly connected with the inner wall of the bottom of the box body (1), a plurality of limiting holes (5) are uniformly arranged at the top of the second supporting plate (4) in a penetrating manner, a plurality of reagent bottles (11) are arranged in the box body (1), the reagent bottles (11) are positioned in the corresponding limiting holes (5), the bottom ends of the reagent bottles (11) are attached to the top of the first rubber pad (2) after penetrating through the top of the first supporting plate (3), a converging groove (12) protruding outwards is formed in the top of the outer wall of each reagent bottle (11), a liquid taking pipe (13) is arranged at the symmetrical position of the outer wall of each reagent bottle (11) and the converging groove (12) in a penetrating manner, and a sealing cover (14) is connected to the outer wall, the novel box is characterized in that a box cover (6) is arranged at the top of the box body (1), the box body (1) is fixedly connected with the box cover (6) through a hasp, and a plurality of placing grooves (7) are formed in the top of the box cover (6).

2. The alpha-L-fucosidase assay kit of claim 1, wherein the assay kit comprises: the appearance of the reagent bottle (11) is frustum-shaped, two opposite side walls of the confluence groove (12) are tangent to the circumferential outer wall of the reagent bottle (11), the confluence groove (12) and the outer wall opposite to the top of the reagent bottle (11) are obliquely arranged, and the included angle between the outer wall and the circumferential outer wall of the reagent bottle (11) is 100-120 degrees.

3. The alpha-L-fucosidase assay kit of claim 1, wherein the assay kit comprises: reagent bottle (11), groove (12), the liquid taking pipe (13) of converging are the integrated into one piece structure, reagent bottle (11), groove (12) of converging, liquid taking pipe (13), sealed lid (14) all are located spacing hole (5), the inner wall of spacing hole (5) and reagent bottle (11), the groove (12) of converging, liquid taking pipe (13), the whole outer wall of sealed lid (14) laminate mutually.

4. The alpha-L-fucosidase assay kit of claim 1, wherein the assay kit comprises: the reagent bottle cover is characterized in that a plurality of springs (8) are uniformly and fixedly connected to the inner wall of the top of the box cover (6) in a multiple mode, a pressing plate (9) is fixedly connected to the bottom of each spring (8) in a common mode, a second rubber pad (10) is arranged at the bottom of each pressing plate (9), and the bottoms of the second rubber pads (10) are attached to the tops of a plurality of reagent bottles (11) in a mutual fit mode.

5. The alpha-L-fucosidase assay kit of claim 1, wherein the assay kit comprises: the shape and the size of the placing groove (7) are matched with the shape and the size of an assembly formed by the reagent bottle (11) and the confluence groove (12).