CN213344110U

CN213344110U - Cell cryopreservation slow cooling device

Info

Publication number: CN213344110U
Application number: CN202021466577.9U
Authority: CN
Inventors: 张冲
Original assignee: Beijing Zhilab Technology Co ltd
Current assignee: Beijing Zhilab Technology Co ltd
Priority date: 2020-07-23
Filing date: 2020-07-23
Publication date: 2021-06-04
Anticipated expiration: 2030-07-23

Abstract

The utility model discloses a slow heat sink of cell cryopreserving, cryopreserving box body including cell procedure cooling, be equipped with box body and apron on the cell procedure cooling cryopreserving box body, the upper end of box body and the lower extreme of apron are equallyd divide and do not are equipped with the trapezoidal breach of first trapezoidal breach of assorted and second, joint of each other between the trapezoidal breach of first trapezoidal breach and second, it does not fixedly cup joint first chimb and second chimb to equally divide on the lateral wall of box body and apron, be equipped with two locking mechanism between first chimb and the second chimb, a plurality of supporting shoes of fixedly connected with on the bottom of box body, the upper end of polylith supporting shoe all is equipped with the test tube groove, all be equipped with the cavity in the lateral wall of a plurality of test tube grooves, the intercommunication sets up between a plurality of cavities, the intercommunication is equipped with. The utility model discloses can not only improve the stability that the cell was stored effectively, the staff of still being convenient for freezes to deposit box body upper cover plate to the cell procedure cooling and opens and close.

Description

Cell cryopreservation slow cooling device

Technical Field

The utility model relates to a biological equipment technical field especially relates to cell cryopreserving slow heat sink.

Background

In the in vitro culture work, the cell is along with the extension of live time, the passage number increases, biological characteristics can change gradually, in order to preserve the activity of cell for a long time, or protect rare cell, often need to carry out cryopreservation with the cell, need carry out slow cooling to the cryopreservation of cell, cell procedure cooling cryopreservation box then can carry out slow cooling to the cell effectively and store, its inside is provided with special isopropanol or liquid nitrogen storage chamber usually, general cell cryopreservation slow cooling device can not improve its stability to the cell storage effectively, and its upper cover plate is opened and the closed process is loaded down with trivial details.

Cell cryopreserving slow heat sink that uses in the existing market mostly can not improve the stability that the cell was stored effectively, and the staff of being not convenient for is opened and is closed cell procedure cooling cryopreserving box body upper cover plate.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving among the prior art stability that the cell freezes deposits slow heat sink and can not improve the cell effectively mostly, and the staff of being not convenient for freezes deposits box body upper cover plate to cell procedure cooling and opens and closed phenomenon, and the cell that proposes freezes deposits slow heat sink, and it can not only improve the stability that the cell was stored effectively, and the staff of still being convenient for freezes deposits box body upper cover plate to cell procedure cooling and opens and close.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

a slow cooling device for cell cryopreservation comprises a cell program cooling cryopreservation box body, wherein a box body and a cover plate are arranged on the cell program cooling cryopreservation box body, a first trapezoidal notch and a second trapezoidal notch which are matched are respectively arranged at the upper end of the box body and the lower end of the cover plate, the first trapezoidal notch and the second trapezoidal notch are mutually clamped, a first convex edge and a second convex edge are respectively fixedly sleeved on the side wall of the box body and the side wall of the cover plate, two locking mechanisms are arranged between the first convex edge and the second convex edge, a plurality of supporting blocks are fixedly connected on the bottom of the box body, test tube grooves are respectively arranged at the upper ends of the supporting blocks, chambers are respectively arranged in the side walls of the test tube grooves, the chambers are communicated with each other, a liquid inlet tube is communicated with the inner wall of one of the chambers, and a sealing cover is arranged on the liquid inlet tube, and a plurality of pressing mechanisms which are uniformly matched with the plurality of test tube grooves are arranged on the top of the cover plate.

Preferably, the joint department between first trapezoidal breach and the trapezoidal breach of second is equipped with sealed the pad, and the leakproofness between first trapezoidal breach and the trapezoidal breach of second can be improved effectively to the setting of sealed pad.

Preferably, the locking mechanism comprises a first wedge-shaped block fixedly connected to the lower end of the second convex edge, the upper end of the first convex edge is provided with a slot matched with the first wedge-shaped block, a limit groove is arranged on the inner wall of one end of the slot, a second wedge-shaped block matched with the limit groove is connected in the limit groove in a sliding way, a plurality of first springs are fixedly connected between the side wall at one end of the second wedge-shaped block and the inner wall at one end of the limiting groove, a slide bar is fixedly connected on the side wall of one end of the second wedge-shaped block, one end of the slide bar penetrates through the side wall of one end of the limiting groove in a sliding manner and is fixedly connected with a driving plate, a limit hole matched with the second wedge-shaped block is arranged on the side wall of one end of the first wedge-shaped block, the first wedge-shaped block is inserted in the slot, the second wedge block is inserted into the limiting hole, and the cover plate is convenient to open and close by workers due to the arrangement of the locking mechanism.

Preferably, hold-down mechanism includes the spring post of fixed connection on the apron top, the lower extreme fixedly connected with clamp plate of spring post, hold-down mechanism's setting can improve the stability of the test tube of storage cell effectively.

Preferably, the spring post includes that both ends are equallyd divide respectively with clamp plate upper end and apron top fixed connection's telescopic link, the cover is equipped with the second spring on the telescopic link, the both ends of second spring are equallyd divide respectively with the top of apron and the upper end fixed connection of clamp plate, and the setting of spring post can cushion the apron effectively.

Preferably, the lower end of the pressing plate is fixedly connected with a rubber cushion pad, and the arrangement of the rubber cushion pad can effectively improve the buffering performance of the pressing plate.

Compared with the prior art, the beneficial effects of the utility model are that:

1. the utility model discloses a set up box body, apron, first trapezoidal breach, the trapezoidal breach of second, first chimb, second chimb and supporting shoe etc. can improve the stability of the test tube of storage cell effectively, and wherein the setting of spring post can cushion the apron effectively, and the setting of rubber buffer pad can improve the shock-absorbing capacity of clamp plate effectively in addition.

2. The utility model discloses a set up box body, apron, first trapezoidal breach, the trapezoidal breach of second, first chimb, second chimb and supporting shoe etc. the staff of being convenient for opens and is closed to the apron, and wherein the setting of the trapezoidal breach of first trapezoidal breach and second can improve the leakproofness between apron and the box body effectively, and the setting of rubber buffer cushion can further improve the leakproofness between apron and the box body in addition.

Drawings

FIG. 1 is a perspective view of a slow cooling device for cell cryopreservation according to the present invention;

FIG. 2 is a schematic view of the external structure of the slow cooling device for cell cryopreservation according to the present invention;

FIG. 3 is an enlarged view of a portion of FIG. 1 at A;

fig. 4 is a partially enlarged view of fig. 1 at B.

In the figure: the test tube comprises a box body 1, a cover plate 2, a first trapezoidal notch 3, a second trapezoidal notch 4, a first convex edge 5, a second convex edge 6, a support block 7, a test tube groove 8, a chamber 9, a liquid inlet tube 10, a sealing cover 11, a sealing gasket 12, a first wedge-shaped block 13, a slot 14, a limiting groove 15, a second wedge-shaped block 16, a first spring 17, a sliding rod 18, a driving plate 19, a limiting hole 20, a spring column 21, a pressing plate 22 and a rubber cushion pad 23.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.

Referring to fig. 1-4, a slow cooling device for cell cryopreservation comprises a cell program cooling cryopreservation box body, wherein a box body 1 and a cover plate 2 are arranged on the cell program cooling cryopreservation box body, a first trapezoidal notch 3 and a second trapezoidal notch 4 which are matched are respectively arranged at the upper end of the box body 1 and the lower end of the cover plate 2, the first trapezoidal notch 3 and the second trapezoidal notch 4 are mutually clamped, a first convex edge 5 and a second convex edge 6 are respectively fixedly sleeved on the side wall of the box body 1 and the side wall of the cover plate 2, two locking mechanisms are arranged between the first convex edge 5 and the second convex edge 6, a plurality of supporting blocks 7 are fixedly connected on the bottom of the box body 1, test tube grooves 8 are respectively arranged at the upper ends of the plurality of supporting blocks 7, chambers 9 are respectively arranged in the side walls of the plurality of test tube grooves 8, the plurality of chambers 9 are communicated, a liquid inlet tube 10 is communicated on the inner wall, be equipped with sealed lid 11 on the feed liquor pipe 10, be equipped with a plurality of hold-down mechanism equalling divide respectively with a plurality of test-tube slot 8 assorted on the top of apron 2.

A sealing gasket 12 is arranged at the joint between the first trapezoidal notch 3 and the second trapezoidal notch 4, the sealing gasket 12 is arranged to effectively improve the sealing property between the first trapezoidal notch 3 and the second trapezoidal notch 4, the locking mechanism comprises a first wedge block 13 fixedly connected to the lower end of a second convex edge 6, the upper end of the first convex edge 5 is provided with a slot 14 matched with the first wedge block 13, the inner wall of one end of the slot 14 is provided with a limit groove 15, the limit groove 15 is connected with a second wedge block 16 matched with the limit groove in a sliding manner, a plurality of first springs 17 are fixedly connected between the side wall of one end of the second wedge block 16 and the inner wall of one end of the limit groove 15, the side wall of one end of the second wedge block 16 is fixedly connected with a slide rod 18, one end of the slide rod 18 is arranged to penetrate through the side wall of one end of the limit groove 15 in a sliding manner and is fixedly connected with a driving plate 19, the side wall of one end, the first wedge-shaped block 13 is inserted into the slot 14, the second wedge-shaped block 16 is inserted into the limiting hole 20, and the locking mechanism is arranged to facilitate opening and closing of the cover plate 2 by workers.

Hold-down mechanism includes spring post 21 of fixed connection on 2 tops of apron, the lower extreme fixedly connected with clamp plate 22 of spring post 21, hold-down mechanism's setting, can improve the stability of the test tube that is equipped with the cell effectively, spring post 21 includes that both ends are equallyd divide do not with clamp plate 22 upper end and 2 top fixed connection's of apron telescopic link, the cover is equipped with the second spring on the telescopic link, the both ends of second spring are equallyd divide do not with the top of apron 2 and the upper end fixed connection of clamp plate 22, the setting of spring post 21, can cushion apron 2 effectively, the lower extreme fixedly connected with rubber buffer pad 23 of clamp plate 22, the setting of rubber buffer pad 23, can improve clamp plate 22's shock.

It should be noted that, the cell program cooling cryopreservation box body can effectively perform slow cooling storage on cells, which is the prior art and is not described herein again.

It should be noted that, as shown in fig. 1, the chambers 9 are all communicated with each other through a pipeline, and the supporting block 7 is transparent, so that the staff can observe the liquid level in the chamber 9 conveniently.

It should be noted that, as shown in fig. 1, the depth of the test tube slot 8 is set to have a plurality of different sizes, so that test tubes with different heights can be stored conveniently.

The working principle is as follows: when the cover plate 2 needs to be opened, a worker can manually pull the two driving plates 19 to further enable the two sliding rods 18 to horizontally move, so that the two second wedge-shaped blocks 16 horizontally move, the two driving plates 19 are pulled until the two second wedge-shaped blocks 16 are separated from the corresponding limiting holes 20, the cover plate 2 can be opened, after the cover plate 2 is opened, the worker can open the sealing cover 11, liquid nitrogen is injected into the liquid inlet pipe 10 through the existing equipment, due to the fact that the multiple cavities 9 are communicated, the worker can fill the multiple cavities 9 with the liquid nitrogen through the liquid inlet pipe 10, the supporting block 7 is transparent, the worker can visually observe the liquid level in the cavities 9, liquid injection is stopped after all the cavities 9 are filled with the liquid nitrogen, the liquid inlet pipe 10 is sealed through the sealing cover 11, it needs to be explained that the nitrogen injection and the sealing of the sealing cover 11 are the prior art, and further description is omitted, after the nitrogen injection is finished, the worker can load the cells to be stored into the corresponding test tubes, then place the test tubes with different height sizes into the corresponding test tube slots 8, and finally clamp the first trapezoidal notch 3 and the second trapezoidal notch 4, as shown in fig. 3, when the first trapezoidal notch 3 and the second trapezoidal notch 4 are clamped, the two first wedges 13 are both pressed down and respectively make the second wedge 16 on the same side move horizontally towards the direction close to the drive plate 19 on the same side, after the two first wedges 13 are all completely inserted into the corresponding slots 14, the two second wedges 16 are both inserted into the corresponding limiting holes 20 under the reset action of the first springs 17 on the same side, thereby completing the locking action on the cover plate 2, after the cover plate 2 is locked, the plurality of press plates 22 can effectively press the test tubes into the test tube slots 8, wherein the spring posts 21 and the rubber buffer cushions 23 are arranged, the homoenergetic cushions 2's suppression effectively, and the setting of first trapezoidal breach 3 and the trapezoidal breach 4 of second and the setting of sealed 12 of filling up in addition can improve the leakproofness between apron 2 and the box body 1 effectively, and it needs to explain that cell procedure cooling freezes deposits the box body and is prior art to the slow cooling of cell, no longer gives details here.

The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.

Claims

1. Cell cryopreserving slow heat sink, freeze and deposit the box body including cell procedure cooling, be equipped with box body (1) and apron (2) on the box body is deposited in cell procedure cooling, its characterized in that, the upper end of box body (1) and the lower extreme of apron (2) are equallyd divide and do not are equipped with first trapezoidal breach (3) of assorted and trapezoidal breach (4) of second, mutually the joint between first trapezoidal breach (3) and the trapezoidal breach of second (4), it has first chimb (5) and second chimb (6) respectively to equallyd divide on the lateral wall of box body (1) and the lateral wall of apron (2), be equipped with two locking mechanism between first chimb (5) and second chimb (6), fixedly connected with a plurality of supporting shoes (7) on the bottom of box body (1), the polylith the upper end of supporting shoe (7) all is equipped with test tube groove (8), it is a plurality of all be equipped with cavity (9) in the lateral wall of test tube groove (8), it is a plurality of communicate the setting between cavity (9), one of them the intercommunication is equipped with feed liquor pipe (10) on the inner wall of cavity (9), be equipped with sealed lid (11) on feed liquor pipe (10), be equipped with on the top of apron (2) a plurality of equallys divide do not with a plurality of test tube groove (8) assorted hold-down mechanism.

2. The slow cooling device for cell cryopreservation according to claim 1, wherein a sealing gasket (12) is arranged at the clamping joint between the first trapezoidal notch (3) and the second trapezoidal notch (4).

3. The slow cooling device for cell cryopreservation according to claim 1, wherein the locking mechanism comprises a first wedge-shaped block (13) fixedly connected to the lower end of the second convex edge (6), a slot (14) matched with the first wedge-shaped block (13) is arranged at the upper end of the first convex edge (5), a limiting groove (15) is arranged on one end inner wall of the slot (14), a second wedge-shaped block (16) matched with the limiting groove (15) is slidably connected in the limiting groove (15), a plurality of first springs (17) are fixedly connected between one end side wall of the second wedge-shaped block (16) and one end inner wall of the limiting groove (15), a sliding rod (18) is fixedly connected to one end side wall of the second wedge-shaped block (16), one end of the sliding rod (18) slides through one end side wall of the limiting groove (15) and is fixedly connected with a driving plate (19), and a limiting position matched with the second wedge-shaped block (16) is arranged on one end side wall of the first wedge-shaped block The first wedge block (13) is inserted into the slot (14), and the second wedge block (16) is inserted into the limiting hole (20).

4. The slow cooling device for cell cryopreservation according to claim 1, wherein the pressing mechanism comprises a spring column (21) fixedly connected to the top of the cover plate (2), and a pressing plate (22) is fixedly connected to the lower end of the spring column (21).

5. The slow cooling device for cell cryopreservation according to claim 4, wherein the spring column (21) comprises a telescopic rod with two ends fixedly connected with the upper end of the pressure plate (22) and the top of the cover plate (2), respectively, the telescopic rod is sleeved with a second spring, and two ends of the second spring are fixedly connected with the top of the cover plate (2) and the upper end of the pressure plate (22), respectively.

6. The slow cooling device for cell cryopreservation according to claim 4, wherein a rubber buffer (23) is fixedly connected to the lower end of the pressure plate (22).