CN213327084U

CN213327084U - Retrieve device of heparin sodium in follow waste water

Info

Publication number: CN213327084U
Application number: CN202022045342.9U
Authority: CN
Inventors: 马保社; 李建华
Original assignee: Yichang Fengrun Biological Technology Co ltd
Current assignee: Yichang Fengrun Biological Technology Co ltd
Priority date: 2020-09-17
Filing date: 2020-09-17
Publication date: 2021-06-01
Anticipated expiration: 2030-09-17

Abstract

The utility model discloses a device for recovering heparin sodium from waste water, which comprises a stirring tank body, wherein a stirring device is arranged in the stirring tank body, the top of the stirring tank body is respectively provided with a waste water feed inlet and a pH regulator feed inlet, the bottom of the stirring tank body is connected with the feed end of a pressurizing tank body through a discharge pipe, a pressure plate is arranged in the pressurizing tank body, one end of the pressure plate is connected with the telescopic end of a hydraulic cylinder, the liquid outlet end of the pressurizing tank body is connected with the feed end of a filtering device through a feed pipe, the liquid outlet end of the filtering device is connected with the input end of a feed pump through a liquid discharge pipe, and the output end of the; the utility model discloses a pressure boost process of the pressure boost jar body makes filtration efficiency improve, through add the elution pipeline on original resin column moreover for adsorb and elution process integration, improved recovery efficiency, finally realize retrieving the purpose of the heparin sodium in the waste water in succession.

Description

Retrieve device of heparin sodium in follow waste water

Technical Field

The utility model relates to a heparin sodium production technical field specifically indicates a retrieve device of heparin sodium from waste water.

Background

Heparin sodium (Heparin sodium) can interfere with many links of the blood coagulation process and has the anticoagulation effect in vivo and in vitro; at present, heparin sodium generally undergoes steps such as raw material treatment, enzymolysis extraction, ion exchange adsorption and refining, wherein partial heparin sodium exists in the waste water generated in the enzymolysis extraction step, the waste water is a mixed solution of extraction raw materials (mainly including pig lung and pancreas pulp particles) and heparin sodium, in the process of treating the waste water, the extraction raw materials need to be separated firstly, and then the heparin sodium is recovered, in addition, the waste water is viscous, the filtering speed and the efficiency are low, no report is found in a continuous complete device for recovering the heparin sodium from the waste water at present, and a device for recovering the heparin sodium from the waste water needs to be designed urgently to solve the problem.

Disclosure of Invention

An object of the utility model is to overcome above-mentioned not enough, provide a retrieve device of heparin sodium in follow waste water, can retrieve the heparin sodium in the waste water in succession.

The utility model discloses a solve above-mentioned technical problem, the technical scheme who adopts is: the utility model provides a retrieve device of heparin sodium from waste water, includes the agitator tank body, the internal agitating unit that is equipped with of agitator tank, agitator tank body top are equipped with waste water feed inlet and pH regulator feed inlet respectively, agitator tank body bottom is passed through the discharging pipe and is connected with the internal feed end of pressure boost jar, the internal pressure disk that is equipped with of pressure boost jar, pressure disk one end is connected with the flexible end of pneumatic cylinder, the internal liquid end of pressure boost jar is connected with the filter equipment feed end through the conveying pipe, the filter equipment liquid end passes through the fluid-discharge tube and is connected with the delivery pump input, the delivery pump output passes through the feed liquor pipe and is connected with resin.

Preferably, the pressurization tank body is further connected with an air suction pipeline, and a one-way valve is arranged on the air suction pipeline.

Preferably, the pressure boost jar body is the cylinder type structure of horizontal setting, and its left and right sides all seals, and the pressure boost jar body is inboard to be equipped with annular retaining ring near the position of discharging pipe, the pressure disk outer lane is equipped with the sealing washer with the pressure boost jar body inboard position of contact.

Preferably, the stirring tank body and the filtering device are both fixed on the ground through a support frame, and the pressurizing tank body is fixedly connected with the support frame through a transverse support.

Preferably, the filtering device comprises a filtering tank and a filtering cylinder arranged in the filtering tank, the filtering cylinder is of a circular truncated cone-shaped cylinder structure, the top of the filtering cylinder is detachably connected with the top of the filtering tank through a connecting ring, a sealing cover is arranged at the top of the filtering tank, a feeding hole connected with a feeding pipe is formed in the center of the sealing cover, and the bottom of the filtering tank is connected with a liquid discharge pipe.

Preferably, the top of the sealing cover, the connecting ring and the filtering tank are all provided with screw holes for penetrating screws.

Preferably, the resin adsorption device comprises a resin column, the upper end and the lower end of the resin column are respectively provided with a partition plate, the resin column is filled with resin, the bottom of the resin column is connected with the liquid inlet pipe, and the top of the resin column is connected with the collecting tank through a drain pipe.

Preferably, the bottom of the resin column is further connected with a liquid outlet pipe, the top of the resin column is further connected with an eluent liquid inlet pipe, and valves are arranged on the liquid inlet pipe, the drain pipe, the liquid outlet pipe and the eluent liquid inlet pipe.

The utility model has the advantages that: the utility model discloses a pressure boost process of the pressure boost jar body makes filtration efficiency improve, through add the elution pipeline on original resin column moreover for adsorb and elution process integration, improved recovery efficiency, finally realize retrieving the purpose of the heparin sodium in the waste water in succession.

Drawings

FIG. 1 is a schematic diagram of an apparatus for recovering heparin sodium from wastewater;

FIG. 2 is a schematic front view of the filter apparatus of FIG. 1;

FIG. 3 is a schematic top view of the closure of FIG. 2;

fig. 4 is a front view of the filter cartridge of fig. 2 in engagement with the connector ring.

Detailed Description

The invention is described in further detail below with reference to the figures and the embodiments.

As shown in fig. 1 to 4, a device for recovering heparin sodium from wastewater comprises a stirring tank body 1, wherein a stirring device 2 is arranged in the stirring tank body 1, a wastewater feed inlet 3 and a pH regulator feed inlet 4 are respectively arranged at the top of the stirring tank body 1, the bottom of the stirring tank body 1 is connected with the feed end of a pressurizing tank body 6 through a discharge pipe 5, a pressure plate 7 is arranged in the pressurizing tank body 6, one end of the pressure plate 7 is connected with the telescopic end of a hydraulic cylinder 8, the liquid outlet end of the pressurizing tank body 6 is connected with the feed end of a filtering device 10 through a feed pipe 9, the liquid outlet end of the filtering device 10 is connected with the input end of a feed pump 12 through a liquid discharge pipe 11, and the output end of the feed pump 12 is connected.

Preferably, the supercharging tank 6 is further connected with an air suction pipeline 15, and a one-way valve 16 is arranged on the air suction pipeline 15. After the one-way valve 16 is designed, when the pressure plate 7 in the pressure boost tank 6 moves leftwards, the pressure boost tank 6 sucks air, so that the air suction pipeline 15 and the one-way valve 16 can suck air, the material in the liquid discharge pipe 11 can be prevented from flowing back into the pressure boost tank 6, when the pressure plate 7 in the pressure boost tank 6 moves rightwards, the pressure boost tank 6 carries out a pressure boost process on the material in the pressure boost tank, and due to the one-way liquidity of the one-way valve 16, the material cannot be discharged from the air suction pipeline 15 but is discharged from the liquid outlet end of the pressure boost tank 6.

Preferably, the pressurizing tank body 6 is a transversely arranged cylindrical structure, the left side and the right side of the pressurizing tank body are both sealed, an annular retainer ring 17 is arranged at the position, close to the discharge pipe 5, of the inner side of the pressurizing tank body 6, and a sealing ring 20 is arranged at the position, in contact with the inner side of the pressurizing tank body 6, of the outer ring of the pressure plate 7. Annular retaining ring 17 can prevent that pressure disk 7 from crossing the position of discharging pipe 5, and sealing washer 20 can guarantee the pressure disk 7 and remove the gas tightness when removing, guarantees the normal work of the pressure boost jar body 6.

Preferably, the stirring tank body 1 and the filtering device 10 are both fixed on the ground through a support frame 18, and the pressurizing tank body 6 is fixedly connected with the support frame 18 through a transverse support 19.

Preferably, the filtering device 10 comprises a filtering tank 10.1 and a filtering cylinder 10.2 arranged in the filtering tank 10.1, the filtering cylinder 10.2 is of a truncated cone-shaped cylinder structure, the top of the filtering cylinder is detachably connected with the top of the filtering tank 10.1 through a connecting ring 10.3, a sealing cover 10.4 is arranged on the top of the filtering tank 10.1, a feeding hole 10.5 connected with a feeding pipe 9 is formed in the center of the sealing cover 10.4, and the bottom of the filtering tank 10.1 is connected with a liquid discharge pipe 11. When the mixed material is introduced into the filtering device 10, the mixed material is filtered by the filter cartridge 10.2 to filter out pig lung and pancreatic pulp particles inside, then the liquid passes through the filtering holes of the filter cartridge 10.2, then enters the filtering tank 10.1, and finally enters the liquid discharge pipe 11 from the bottom of the filtering tank 10.1 to be discharged, and because the connecting ring 10.3 is detachably connected with the top of the filtering tank 10.1, the sealing cover 10.4 and the filter cartridge 10.2 can be taken down to be cleaned after the pig lung and pancreatic pulp particles trapped in the filter cartridge 10.2 reach a certain amount.

Preferably, the top of the sealing cover 10.4, the connecting ring 10.3 and the filter tank 10.1 are all provided with screw holes 10.6 for passing screws.

Preferably, the resin adsorption device 14 comprises a resin column 14.1, the upper end and the lower end of the resin column 14.1 are both provided with a partition plate 14.2, the resin column 14.1 is filled with resin 14.3, the bottom of the resin column 14.1 is connected with a liquid inlet pipe 13, and the top of the resin column 14.1 is connected with a collecting tank 14.5 through a sewage discharge pipe 14.4. In this embodiment, the resin 14.3 filled in the resin column 14.1 is D204 resin or D254 resin to adsorb heparin sodium in the feed liquid.

Preferably, the bottom of the resin column 14.1 is further connected with a liquid outlet pipe 14.6, the top of the resin column 14.1 is further connected with an eluent liquid inlet pipe 14.7, and valves are arranged on the liquid inlet pipe 13, the sewage discharge pipe 14.4, the liquid outlet pipe 14.6 and the eluent liquid inlet pipe 14.7. After the resin 14.3 adsorbs heparin sodium, the heparin sodium needs to be eluted from the resin 14.3, at this time, valves on the liquid inlet pipe 13 and the drain pipe 14.4 can be closed, then valves on the eluent liquid inlet pipe 14.7 and the liquid outlet pipe 14.6 are opened, eluent is pumped into the eluent liquid inlet pipe 14.7 and then enters the resin column 14.1, the heparin sodium adsorbed in the resin 14.3 is eluted, and then the heparin sodium flows out from the liquid outlet pipe 14.6 and enters the subsequent refining process.

The working principle of the embodiment is as follows:

firstly, the wastewater in the embodiment comprises a mixed solution of extraction raw materials (mainly pig lung and pancreas pulp particles) and heparin sodium, the mixed solution is added into a stirring tank body 1 through a wastewater inlet 3, then the stirring process is carried out through a stirring device 2, and acid liquor or alkali liquor is added through a pH regulator inlet 4 to adjust the pH value of the wastewater so as to facilitate the subsequent ion exchange adsorption process; then the uniformly mixed wastewater enters a pressurizing tank body 6 through a discharge pipe 5, a hydraulic cylinder 8 is started, a telescopic rod of the hydraulic cylinder periodically extends or contracts, when a pressure plate 7 in the pressurizing tank body 6 moves rightwards, the pressurizing tank body 6 performs a pressurizing process on materials in the pressurizing tank body, so that the materials are quickly introduced into a filtering device 10, specifically, the materials are filtered through a filter cylinder 10.2 to filter out pig lung and pancreas pulp particles in the materials, then the liquid passes through a filtering hole of the filter cylinder 10.2 and then enters a filter tank 10.1, and finally enters a liquid discharge pipe 11 from the bottom of the filter tank 10.1 to be discharged, and as a connecting ring 10.3 is detachably connected with the top of the filter tank 10.1, when the pig lung and the pancreas pulp particles intercepted in the filter cylinder 10.2 reach a certain amount, a sealing cover 10.4 and the filter cylinder 10.2 can be taken down to be cleaned; the filtered wastewater is conveyed into a resin adsorption device 14 through a liquid inlet pipe 13 by a feeding pump 12, the feed liquid enters a resin column 14.1 from the liquid inlet pipe 13 at the lower part, and after resin 14.3 filled in the resin column 14.1 adsorbs heparin sodium in the feed liquid, the feed liquid flows into a collecting tank 14.5 from a sewage discharge pipe 14.4 at the upper part; after the resin 14.3 finishes the process of adsorbing heparin sodium, heparin sodium needs to be eluted from the resin 14.3, valves on the liquid inlet pipe 13 and the drain pipe 14.4 can be closed, then valves on the eluent liquid inlet pipe 14.7 and the liquid outlet pipe 14.6 are opened, eluent is pumped into the eluent liquid inlet pipe 14.7 and then enters the resin column 14.1, the heparin sodium adsorbed in the resin 14.3 is eluted, and then the heparin sodium flows out of the liquid outlet pipe 14.6 and enters the subsequent refining process.

The above embodiments are merely preferred technical solutions of the present invention, and should not be considered as limitations of the present invention, and the features in the embodiments and the examples in the present application may be arbitrarily combined with each other without conflict. The protection scope of the present invention shall be defined by the claims and the technical solutions described in the claims, including the technical features of the equivalent alternatives as the protection scope. Namely, equivalent alterations and modifications within the scope of the invention are also within the scope of the invention.

Claims

1. The utility model provides a retrieve device of heparin sodium in follow waste water, includes agitator tank body (1), be equipped with agitating unit (2) in agitator tank body (1), agitator tank body (1) top is equipped with waste water feed inlet (3) and pH regulator feed inlet (4) respectively, its characterized in that: the stirring tank body (1) bottom is connected with the charging end of the supercharging tank body (6) through a discharging pipe (5), a pressure plate (7) is arranged in the supercharging tank body (6), one end of the pressure plate (7) is connected with the telescopic end of a hydraulic cylinder (8), the liquid outlet end of the supercharging tank body (6) is connected with the charging end of a filtering device (10) through a feeding pipe (9), the liquid outlet end of the filtering device (10) is connected with the input end of a feeding pump (12) through a liquid discharging pipe (11), and the output end of the feeding pump (12) is connected with a resin adsorption device (14) through a liquid inlet pipe (13).

2. The apparatus for recovering heparin sodium from wastewater as claimed in claim 1, wherein: the supercharging tank body (6) is further connected with an air suction pipeline (15), and a one-way valve (16) is arranged on the air suction pipeline (15).

3. The apparatus for recovering heparin sodium from wastewater as claimed in claim 1, wherein: the pressure boost jar body (6) is the cylinder type structure of horizontal setting, and its left and right sides all seals, and the pressure boost jar body (6) inboard position of being close to discharging pipe (5) is equipped with annular retaining ring (17), pressure disk (7) outer lane is equipped with sealing washer (20) with the inboard position of contacting of pressure boost jar body (6).

4. The apparatus for recovering heparin sodium from wastewater as claimed in claim 1 or 3, wherein: the stirring tank body (1) and the filtering device (10) are both fixed on the ground through a support frame (18), and the pressurizing tank body (6) is fixedly connected with the support frame (18) through a transverse support (19).

5. The apparatus for recovering heparin sodium from wastewater as claimed in claim 1, wherein: the filter device (10) comprises a filter tank (10.1) and a filter cylinder (10.2) arranged in the filter tank (10.1), the filter cylinder (10.2) is of a round-table-shaped cylinder structure, the top of the filter cylinder is detachably connected with the top of the filter tank (10.1) through a connecting ring (10.3), the top of the filter tank (10.1) is provided with a sealing cover (10.4), the center of the sealing cover (10.4) is provided with a feeding hole (10.5) connected with a feeding pipe (9), and the bottom of the filter tank (10.1) is connected with a liquid discharge pipe (11).

6. The apparatus for recovering heparin sodium from wastewater as claimed in claim 5, wherein: the top of the sealing cover (10.4), the connecting ring (10.3) and the top of the filtering tank (10.1) are all provided with screw holes (10.6) for penetrating screws.

7. The apparatus for recovering heparin sodium from wastewater as claimed in claim 1, wherein: the resin adsorption device (14) comprises a resin column (14.1), wherein the upper end and the lower end of the resin column (14.1) are respectively provided with a partition plate (14.2), the resin column (14.1) is filled with resin (14.3), the bottom of the resin column (14.1) is connected with a liquid inlet pipe (13), and the top of the resin column (14.1) is connected with a collecting tank (14.5) through a drain pipe (14.4).

8. The apparatus for recovering heparin sodium from wastewater as claimed in claim 7, wherein: the bottom of the resin column (14.1) is also connected with a liquid outlet pipe (14.6), the top of the resin column (14.1) is also connected with an eluent liquid inlet pipe (14.7), and valves are arranged on the liquid inlet pipe (13), the sewage discharge pipe (14.4), the liquid outlet pipe (14.6) and the eluent liquid inlet pipe (14.7).