CN213250334U - Ophthalmic cutting system - Google Patents
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- CN213250334U CN213250334U CN202020667872.4U CN202020667872U CN213250334U CN 213250334 U CN213250334 U CN 213250334U CN 202020667872 U CN202020667872 U CN 202020667872U CN 213250334 U CN213250334 U CN 213250334U
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Abstract
The utility model provides an ophthalmology cutting system, include from mode locking all-fiber femto second laser instrument, beam plastic system, spectroscope, laser galvanometer scanning system, optical coherence tomography imaging system, cornea topography, people's eye butt joint system, data analysis processing system, new line display system and control system, the utility model provides an ophthalmology cutting method can use optical coherence tomography system (OCT) and cornea topography to carrying out the regional and regional image information's of eye tissue depth real-time collection, realizes the accurate focus and the location to the femto second laser beam during cutting eye tissue to on removing cutting tissue plane with lens, effectively be used for the accurate cutting of eye tissue, improve the accuracy and the security of operation.
Description
Technical Field
The utility model relates to the technical field of medical equipment, in particular to ophthalmology cutting system.
Background
After the femtosecond laser is emitted from the laser instrument, when the instantaneous power density reaches or exceeds a specific threshold value, the irradiated tissue forms plasma due to the multi-photon absorption effect, and the plasma micro-explosion effect is generated, and a certain degree of shock wave is formed. The continuous micro-blasting effect enables all micro-blasting points to be connected into a line and the line to be connected into a plane, thereby achieving extremely precise tissue cutting effect. Femtosecond lasers are increasingly applied to various ophthalmic diseases, including anterior segment laser therapy and fundus laser therapy. The anterior segment of the eye and the fundus tissue are very different in position, shape, density, thickness, etc.
Currently, an optical coherence imaging system (OCT) is used for imaging the internal structure of the eye tissue to guide femtosecond laser eye tissue cutting, but the tissues with similar density and tissue structure on the ocular surface can not be distinguished. The corneal topography can be used for preoperative examination and postoperative curative effect evaluation of corneal refractive surgery, corneal properties, particularly astigmatism, are fully known before surgery according to the corneal topography, and corneal distortion induced by a keratoconus and a contact lens is eliminated; after operation, the effect is evaluated according to the corneal topography. The goal of modern cataract surgery is not only to reduce surgically-induced astigmatism, but also to neutralize preoperative astigmatism through the surgical incision. The surgery can thus be guided on the basis of the topography of the cornea examined before the surgery. The corneal topography is used for making accurate diagnosis for the corneal astigmatism after the corneal transplantation and guiding and correcting the astigmatism after the corneal transplantation.
In order to obtain the best cutting effect, an optical coherence imaging system (OCT) is used for collecting image information of an eye tissue depth area in an operation, and corneal topographic information is collected by using a corneal topographic map, so that the eye tissue is cut more accurately; meanwhile, in the operation, the femtosecond laser pulse is guided to be accurately positioned and focused on the eye tissue in real time, and the method has very urgent application requirements on the accurate cutting of the femtosecond laser eye tissue.
SUMMERY OF THE UTILITY MODEL
In view of the above, there is a need to provide an ophthalmic cutting system that is effective for precise cutting of eye tissue and that improves the accuracy and safety of the procedure, in response to the deficiencies of the prior art.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
the utility model provides an ophthalmology cutting system, includes self-locking mode all-fiber femto second laser instrument, beam shaping system, spectroscope, laser galvanometer scanning system, optical coherence tomography imaging system, corneal topography, people's eye butt joint system, data analysis processing system, new line display system and control system, wherein:
the femtosecond pulse laser beam emitted by the self-mode-locking all-fiber femtosecond laser enters the beam shaping system through the fiber transmission line, and the initial femtosecond pulse laser beam after passing through the beam shaping system is converted into a femtosecond pulse laser beam with phase modulation;
the femtosecond pulse laser beam modulated by the phase enters the laser galvanometer scanning system through the spectroscope, and enters the corneal topography and the optical coherence tomography imaging system after being scanned by the laser galvanometer scanning system, the optical coherence tomography imaging system collects image information of an ocular tissue depth area, and the corneal topography collects image information of a corneal area;
the data analysis processing system processes the image information of the eye tissue depth area and the image information of the cornea area, the head-up display system displays the real-time image information processed by the data analysis processing system, the control system sends an instruction according to the real-time image information to adjust the energy of the femtosecond pulse laser beam emitted by the self-mode-locking all-fiber femtosecond laser, and the human eye docking system focuses and docks the adjusted femtosecond pulse laser beam to an eye tissue plane to be cut, so that the accurate cutting of the eye tissue is realized.
In some preferred embodiments, the wavelength of the self-mode-locked all-fiber femtosecond laser is 1064 +/-5 nm, the pulse width is 300fs-500fs, the pulse frequency is 10kHz-200kHz, the pulse energy is 10 muJ-30 muJ, the beam diameter is 3 +/-1 μ M, and the beam quality M2 is less than 1.2.
In some preferred embodiments, the beam shaping system includes a spatial light modulator, a first convex lens and a second convex lens, which are sequentially disposed, the first convex lens and the second convex lens are located on a micro self-locking slide rail, and the first convex lens and the second convex lens can move along the micro self-locking slide rail.
In some preferred embodiments, the optical fiber transmission line is an active optical fiber, the active optical fiber is made of quartz, the core diameter is 120 μm-180 μm, and the core is doped with rare earth elements.
In some preferred embodiments, the rare earth element is one or more of neodymium, ytterbium, erbium, thulium, holmium, dysprosium, praseodymium, and the like.
In some preferred embodiments, the center of the suction ring, the center of focus, and the center of the area of ocular tissue of the human eye docking system are located on the same horizontal line.
In addition, the utility model also provides an ophthalmology cutting method of ophthalmology cutting system, its characterized in that includes following step:
step S110: the femtosecond pulse laser beam enters the beam shaping system through an optical fiber transmission line, and the initial femtosecond pulse laser beam after passing through the beam shaping system is converted into a femtosecond pulse laser beam with phase modulation and enters the laser galvanometer scanning system through the spectroscope;
step S120: the laser galvanometer scanning system scans the position information determined by eye tissues in real time and transmits the position information to the optical coherence tomography imaging system and the corneal topography;
step S130: the optical coherence tomography imaging system and the corneal topography focus femtosecond pulse laser beams emitted by the self-mode-locked all-fiber femtosecond laser on eye tissues, perform real-time three-dimensional measurement on depth regions and corneal regions of the eye tissues, and transmit results to the data analysis processing system in real time;
step S140: the data analysis processing system processes the real-time image information of the eye tissue depth area and the cornea area acquired by the optical coherence tomography imaging system and the corneal topography and transmits the result to the head-up display system;
step S150: the head-up display system displays the real-time image information analyzed by the data analysis processing system and then transmits the data information to the control system;
step S160: the control system sends out an instruction according to the real-time image information to adjust the energy of the femtosecond pulse laser beam emitted by the self-mode-locking all-fiber femtosecond laser;
step S170: the human eye docking system focuses and docks the adjusted femtosecond pulse laser beam to an eye tissue plane to be cut, so that accurate cutting of the eye tissue is achieved.
The utility model adopts the above technical scheme's advantage is:
the utility model provides an ophthalmology cutting system and cutting method can use optical coherence imaging system (OCT) and cornea topography to carry out the regional and regional image information's of eye tissue depth real-time collection of cornea, realizes accurate focus and the location to the femto second laser beam during cutting eye tissue to on removing cutting tissue plane with reflection lens, effectively be used for the accurate cutting of eye tissue, improve the accuracy and the security of operation.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic structural diagram of an ophthalmic cutting system provided in embodiment 1 of the present invention.
Fig. 2 is a flowchart illustrating the steps of an ophthalmic cutting method according to embodiment 2 of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
Example 1
Please refer to fig. 1, which is a schematic structural diagram of an ophthalmic cutting system according to the present invention, which includes a self-mode-locked all-fiber femtosecond laser 110, a beam shaping system 120, a beam splitter 130, a laser galvanometer scanning system 140, an optical coherence tomography imaging system 150, a corneal topography 160, a human eye docking system 170, a data analysis processing system 180, a head-up display system 190 and a control system 210.
The utility model provides an ophthalmology cutting system, its working method as follows:
the femtosecond pulse laser beam emitted from the self-mode-locked all-fiber femtosecond laser 110 enters the beam shaping system 120 through a fiber transmission line, and the initial femtosecond pulse laser beam after passing through the beam shaping system is converted into a phase-modulated femtosecond pulse laser beam.
The femtosecond pulse laser beam modulated by the phase passes through the beam splitter 130 and enters the laser galvanometer scanning system 140, and enters the corneal topography 160 and the optical coherence tomography imaging system 150 after being scanned by the laser galvanometer scanning system 140.
The optical coherence tomography imaging system 150 captures image information of a depth region of ocular tissue and the corneal topography 160 captures image information of a corneal region.
The data analysis processing system 180 processes the image information of the depth region of the eye tissue and the image information of the cornea region, the head-up display system 190 displays the real-time image information processed by the data analysis processing system 180, the control system 210 sends an instruction according to the real-time image information to adjust the energy of the femtosecond pulse laser beam emitted by the self-mode-locked all-fiber femtosecond laser 110, and the human eye docking system 170 focuses and docks the adjusted femtosecond pulse laser beam onto the plane of the eye tissue to be cut, so that the accurate cutting of the eye tissue is realized.
In some preferred embodiments, the light beam transmission line is an active optical fiber, the active optical fiber is made of quartz, the core diameter is 120 μm-180 μm, and the core is doped with rare earth elements.
In some preferred embodiments, the rare earth element is one or more of neodymium, ytterbium, erbium, thulium, holmium, dysprosium, praseodymium, and the like.
It will be appreciated that the active fiber produces new light waves or amplified optical signals, enabling a range of laser outputs in narrow linewidth, single frequency, continuous or pulsed lasers.
In some preferred embodiments, the self-mode-locked all-fiber femtosecond laser 110 has a wavelength of 1064 + -5 nm, a pulse width of 300fs-500fs, a pulse frequency of 10kHz-200kHz, a pulse energy of 10 muJ-30 muJ, a beam diameter of 3 + -1 μ M, and a beam mass M2 of less than 1.2.
It is understood that the energy of the femtosecond pulse laser beam emitted from the mode-locked all-fiber femtosecond laser 110 can be adjusted according to the instruction of the control system 210.
In some preferred embodiments, the beam shaping system 120 includes a spatial light modulator 121, a first convex lens 122 and a second convex lens 123, which are sequentially disposed, the first convex lens 122 and the second convex lens 123 are located on a micro self-locking slide rail, and the first convex lens 122 and the second convex lens 123 are movable along the micro self-locking slide rail.
In some preferred embodiments, the laser galvanometer scanning system 140 is a three-dimensional scanning galvanometer combination that can direct the femtosecond pulsed laser beam to scan at a focal position in real time.
It can be understood that under the action of the laser galvanometer scanning system 140, the position of the light beam in the XYZ axis direction can be adjusted, and since the galvanometer deflection speed of the laser galvanometer scanning system 140 is extremely fast, the three-dimensional scanning time is shortened, and the operation time is saved.
In some preferred embodiments, the optical coherence tomography imaging system 150 has an imaging depth of up to 8 mm; the number of scanning frames per second is 100; the number of scanning times is 20 ten thousand times/second; the withdrawal speed is 20 mm/s; wavelength 820-; the system sensitivity is 6dB/3mm-20dB/3 mm; the maximum power is 2.5mW-3.0 mW.
In some preferred embodiments, the corneal topography 160 can be used for pre-operative and post-operative treatment evaluation of refractive corneal surgery, to guide cataract surgery, to diagnose and correct corneal astigmatism following corneal transplant surgery.
It will be appreciated that during actual surgery, the optical coherence tomography imaging system 150 acquires image information of a depth zone of eye tissue and the corneal topography 160 acquires image information of a corneal zone, thereby providing precise guidance for the focusing and positioning of the surgical laser beam to adjust and verify the position and orientation of the selected surgical mode, and the surgical laser system that uses the determined corneal shape change information to direct laser pulses into the lens of the eye, effective for precise surgical procedures in the eye.
In some preferred embodiments, the center of the suction ring, the center of focus, and the center of the area of ocular tissue of the human eye docking system 170 are located on the same horizontal line.
It can be understood that the eyeball is sucked by the negative pressure suction ring, and the eyeball is prevented from moving in the femtosecond laser cutting process, so that the use of the negative pressure suction ring can greatly improve the operation safety of the laser.
It is understood that, based on the real-time image information determined by the optical coherence tomography imaging system 150 and the real-time image information determined by the corneal topography 160, the control system 210 sends instructions to adjust the energy of the femtosecond pulse laser beam emitted by the self-mode-locked all-fiber femtosecond laser according to the real-time image information, so as to precisely cut the eye tissue such as cornea, limbus, pupil, sclera, iris, crystalline lens, ciliary muscle, vitreous body or retina, and modify the surgical plan in real time.
In some preferred embodiments, the head-up display system 190 includes a CCD camera that receives reflected light from eye tissue and displays image information collected by the oct system 150, the corneal topography 160, and the galvanometer laser scanning system 140.
It can be appreciated that the data display screen of the heads-up display system 190 is a touch screen, and the doctor can select laser data, view images and start and stop the device at any time.
It will be appreciated that integrating the heads-up display system 190 into the surgical microscope can simultaneously display the images of the optical coherence tomography imaging system 150, the corneal topography 160, and the laser galvanometer scanning system 140 without the need for three separate image display systems, ensuring that the physician can visualize the data without interrupting the procedure (in real time); in addition, the position and orientation of the selected surgical mode may also be adjusted and verified by capturing positional information in the image to guide the focus and positioning of the surgical laser during surgery.
The control system 210 can send instructions to adjust the energy of the femtosecond pulse laser beam emitted by the self-mode-locked all-fiber femtosecond laser 110 according to the real-time determined image information of the depth region of the eye tissue scanned by the optical coherence tomography imaging system 150 and the real-time determined image information of the cornea region scanned by the corneal topography 160, so as to precisely cut eye tissues such as cornea, limbus, pupil, sclera, iris, crystalline lens, ciliary muscle, vitreous body or retina, and can modify the surgical plan in real time.
The femtosecond laser pulse can change the energy according to the real-time eye tissue shape change information, can not cause eye injury, has better postoperative feeling of a patient, simple and convenient operation, short treatment course and quick healing, and becomes a humanized, safe and effective cutting technology.
The utility model provides an ophthalmology cutting system can use optical coherence imaging system (OCT) and cornea topography to carry out the regional and regional image information's of eye tissue depth real-time collection of cornea, realizes accurate focus and the location to the femto second laser beam during cutting eye tissue to on moving cutting tissue plane with reflection lens, effectively be used for the accurate cutting of eye tissue, improve the accuracy and the security of operation.
Furthermore, the utility model provides an eye tissue cutting device adopts non-contact, infiltration formula's butt joint interface, through liquid contact cornea rather than the awl mirror direct contact cornea, the cornea extrusion is little to avoided contact patient interface can produce that the cornea fold can produce irregular scattering damage corneal tissue or amazing iris and make the pupil shrink.
Example 2
Referring to fig. 2, a flow chart of the steps of an ophthalmic cutting method of an ophthalmic cutting system according to an embodiment of the present invention is provided, which includes the following steps:
step S110: the femtosecond pulse laser beam enters the beam shaping system through an optical fiber transmission line, and the initial femtosecond pulse laser beam after passing through the beam shaping system is converted into a femtosecond pulse laser beam with phase modulation and enters the laser galvanometer scanning system through the spectroscope;
step S120: the laser galvanometer scanning system scans the position information determined by eye tissues in real time and transmits the position information to the optical coherence tomography imaging system and the corneal topography;
step S130: the optical coherence tomography imaging system and the corneal topography focus femtosecond pulse laser beams emitted by the self-mode-locked all-fiber femtosecond laser on eye tissues, perform real-time three-dimensional measurement on depth regions and corneal regions of the eye tissues, and transmit results to the data analysis processing system in real time;
step S140: the data analysis processing system processes the real-time image information of the eye tissue depth area and the cornea area acquired by the optical coherence tomography imaging system and the corneal topography and transmits the result to the head-up display system;
step S150: the head-up display system displays the real-time image information analyzed by the data analysis processing system and then transmits the data information to the control system;
step S160: the control system sends out an instruction according to the real-time image information to adjust the energy of the femtosecond pulse laser beam emitted by the self-mode-locking all-fiber femtosecond laser;
step S170: the human eye docking system focuses and docks the adjusted femtosecond pulse laser beam to an eye tissue plane to be cut, so that accurate cutting of the eye tissue is achieved.
The utility model provides an ophthalmology cutting method can use optical coherence imaging system (OCT) and cornea topography to carry out the regional and regional image information's of eye tissue depth real-time collection of cornea, realizes accurate focus and the location to the femto second laser beam during cutting eye tissue to on moving cutting tissue plane with reflection lens, effectively be used for the accurate cutting of eye tissue, improve the accuracy and the security of operation.
Furthermore, the utility model provides an eye tissue cutting device adopts non-contact, infiltration formula's butt joint interface, through liquid contact cornea rather than the awl mirror direct contact cornea, the cornea extrusion is little to avoided contact patient interface can produce that the cornea fold can produce irregular scattering damage corneal tissue or amazing iris and make the pupil shrink.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
Of course, the anode material for the ophthalmologic cutting system of the present invention may also have various changes and modifications, and is not limited to the specific structure of the above embodiment. In conclusion, the scope of the present invention should include those changes or substitutions and modifications which are obvious to those of ordinary skill in the art.
Claims (4)
1. The utility model provides an ophthalmology cutting system, its characterized in that includes from mode locking all-fiber femto second laser instrument, beam shaping system, spectroscope, laser galvanometer scanning system, optical coherence tomography imaging system, cornea topography, people's eye butt joint system, data analysis processing system, new line display system and control system, wherein:
the femtosecond pulse laser beam emitted by the self-mode-locking all-fiber femtosecond laser enters the beam shaping system through the fiber transmission line, and the initial femtosecond pulse laser beam after passing through the beam shaping system is converted into a femtosecond pulse laser beam with phase modulation;
the femtosecond pulse laser beam modulated by the phase enters the laser galvanometer scanning system through the spectroscope, and enters the corneal topography and the optical coherence tomography imaging system after being scanned by the laser galvanometer scanning system;
the optical coherence tomography imaging system collects image information of an eye tissue depth area, and the corneal topography collects image information of a corneal area;
the data analysis processing system processes the image information of the eye tissue depth area and the image information of the cornea area, the head-up display system displays the real-time image information processed by the data analysis processing system, the control system sends an instruction according to the real-time image information to adjust the energy of the femtosecond pulse laser beam emitted by the self-mode-locking all-fiber femtosecond laser, and the human eye docking system focuses and docks the adjusted femtosecond pulse laser beam to an eye tissue plane to be cut, so that the accurate cutting of the eye tissue is realized.
2. An ophthalmic cutting system as claimed in claim 1, wherein said self-mode-locked all-fiber femtosecond laser has a wavelength of 1064 ± 5nm, a pulse width of 300fs to 500fs, a pulse frequency of 10kHz to 200kHz, a pulse energy of 10 μ J to 30 μ J, a beam diameter of 3 ± 1 μ M, and a beam mass M2< 1.2.
3. The ophthalmic cutting system of claim 1, wherein the beam shaping system comprises a spatial light modulator, a first convex lens and a second convex lens arranged in sequence, the first convex lens and the second convex lens being positioned on a micro-scale micro self-locking slide, the first convex lens and the second convex lens being movable along the micro-scale micro self-locking slide.
4. An ophthalmic cutting system according to claim 1, wherein the center of the suction ring, the center of focus, and the center of the zone of eye tissue of the human eye docking system are located on the same horizontal line.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111407508A (en) * | 2020-04-27 | 2020-07-14 | 季华实验室 | Ophthalmologic cutting system and ophthalmologic cutting method |
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| CN111407508A (en) * | 2020-04-27 | 2020-07-14 | 季华实验室 | Ophthalmologic cutting system and ophthalmologic cutting method |
| CN111407508B (en) * | 2020-04-27 | 2024-03-15 | 季华实验室 | Ophthalmic cutting system and ophthalmic cutting method |
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