CN213220559U - Modeling device for accurately exposing local radioactive damage of rat - Google Patents
Modeling device for accurately exposing local radioactive damage of rat Download PDFInfo
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- CN213220559U CN213220559U CN202021544827.6U CN202021544827U CN213220559U CN 213220559 U CN213220559 U CN 213220559U CN 202021544827 U CN202021544827 U CN 202021544827U CN 213220559 U CN213220559 U CN 213220559U
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Abstract
The utility model provides a modeling device for accurately exposing partial radioactive damage of a rat, wherein a fixed frame is sleeved in a radiation-proof cover and comprises a bottom plate, and the bottom plate comprises a first plate section and a second plate section; a head baffle is arranged on one side of the first plate section, and the lower end of the head baffle is connected with the first plate section; the two sides of the second plate section are respectively provided with a four-limb fixing plate, the lower end of the four-limb fixing plate is connected with the second plate section, the upper end of the four-limb fixing plate is detachably connected with a cover plate, the inner side wall of one end of the four-limb fixing plate, which is close to the first plate section, is provided with a first clamping groove, and a head fixing block is detachably connected in the first clamping groove; the second plate section is provided with a plurality of second clamping grooves, and the tail bone fixing blocks are detachably connected in the second clamping grooves. The utility model provides a pair of accurate modeling device who exposes local radioactive damage of rat, design benefit both can guarantee that the accuracy exposes the mandible and carry out accurate and the shining of capacity, and other non-irradiation area of rat obtain good radiation protection simultaneously.
Description
Technical Field
The utility model belongs to the technical field of medical instrument, a accurate modeling device who exposes rat local radiation damage is related to.
Background
At present, when an RS-2000 biological irradiator is used for rat radioactive osteonecrosis modeling, most of the existing modeling devices are simple lead plates. When the irradiation device is used, the irradiation area is exposed for irradiation after the lead plate is manually bent, the irradiation part can not be accurately reacted, and the operation effects of different operators are different, cannot be unified and standardized, and are difficult to repeat. The size, position, etc. of the irradiation area cannot be obtained accurately.
Meanwhile, when the existing modeling device carries out radioactive irradiation on a rat, the requirement on rat anesthesia is higher. If the anesthesia is too shallow, the rat is easy to shift in the operation, and the experiment can not be carried out according to the expected positioning; if the anesthesia is too deep, the rat can not be successfully resuscitated due to the fact that the anesthesia is too high in the operation, the death rate is increased, the experiment difficulty is increased, and the success rate is reduced.
Therefore, there is a need for an improved modeling apparatus for local radioactive injury of rats.
SUMMERY OF THE UTILITY MODEL
In view of the above shortcomings of the prior art, an object of the present invention is to provide a modeling apparatus for accurately exposing local radiation damage of a rat, which can provide a mandible and a femur of the rat accurately exposed while fixing the rat when the RS-2000 irradiator irradiates the rat locally.
To achieve the above and other related objects, the present invention provides a modeling apparatus for accurately exposing local radiation injury of a rat, comprising:
the radiation protection cover is provided with at least one radiation opening;
the fixing frame is sleeved in the radiation shield and comprises a bottom plate, and the bottom plate comprises a first plate section and a second plate section; a head baffle is arranged on one side of the first plate section, and the lower end of the head baffle is connected with the first plate section; four-limb fixing plates are respectively arranged on two sides of the second plate section, the lower ends of the four-limb fixing plates are connected with the second plate section, and the upper ends of the four-limb fixing plates are detachably connected with cover plates; a first clamping groove is formed in the inner side wall of one end, close to the first plate section, of the four-limb fixing plate, and a head fixing block is detachably connected in the first clamping groove; and a plurality of second clamping grooves are formed in the second plate section, and tail bone fixing blocks are detachably connected in the second clamping grooves.
Preferably, the radiation protection cover is a hollow box body with two open ends.
Preferably, the thickness of the radiation shield is 3-5 mm.
Preferably, the length of the radiation shield is 30-40 cm; the width of the radiation shield is 6-10 cm.
Preferably, the length of the radiation opening is 2-3 cm; the width of the radiation opening is 1-2 cm.
Preferably, the lower end of the head baffle is connected with the top surface of the first plate section, and the head baffle is perpendicular to the first plate section.
Preferably, the first plate section is 2.0-3.0cm higher than the second plate section.
Preferably, the head baffle includes a first baffle section and a second baffle section, a wide surface of the second baffle section is perpendicular to a top surface of the first plate section, and a wide surface of the first baffle section is parallel to and directly above the top surface of the first plate section.
Preferably, the lower part of the head fixing block is provided with a neck opening. The neck opening is semicircular and used for clamping the neck of the rat so as to fix the head of the rat.
Preferably, the lower end of the limb fixing plate is connected with the side surface of the second plate section, and the limb fixing plate is perpendicular to the second plate section.
Preferably, the limb fixation plates on both sides of the second plate segment remain symmetrical.
Preferably, the limb fixing plate is provided with a forelimb opening, a hindlimb opening and a femur opening; the front limb opening, the rear limb opening and the femur opening are positioned at the lower part of the four-limb fixing plate and are sequentially arranged from near to far away from the first plate section; the upper parts of the four limb fixing plates arranged on two sides of the second plate section are matched to form a back opening.
The front limb opening is semicircular and used for fixing the front limb of a rat, the rear limb opening is semielliptical and used for fixing the rear limb of the rat, the femur opening is rectangular and used for providing a supporting point for fixing the femur of the rat, and the back opening is long-strip-shaped and used for exposing the side back of the rat.
Preferably, the top of the limb fixing plate is provided with a plurality of grooves. The groove is positioned on the four-limb fixing plate below the back opening and used for providing a binding point for a binding piece for fixing a rat.
Preferably, the cover plate is detachably connected with the limb fixing plate through a snap fastener.
Preferably, the tail bone fixing block is provided with a tail opening. The tail opening is circular and is used for enabling the tail of the rat to penetrate through the tail bone fixing block, so that the tail of the rat is fixed.
Preferably, the fixing frame further comprises a femur fixing strip, a plurality of snap fasteners are arranged on the femur fixing strip, and the femur fixing strip penetrates through the femur opening and is looped through the snap fasteners.
As above, the utility model provides a pair of accurate modeling device who exposes rat local radiation damage has following beneficial effect:
(1) the utility model provides a pair of accurate modeling device who exposes local radiation damage of rat can fix the rat head and expose through the mount, and then plays the effect of fixed mandible.
(2) The utility model provides a pair of accurate modeling device who exposes local radioactive injury of rat, operation simple accurate can be accomplished within 1min of whole fixed process.
(3) The utility model provides a pair of accurate modeling device who exposes local radiation damage of rat, good fixed messenger shines and need not to accomplish under dark anesthesia, has avoided the anesthesia to lead to the dead risk of rat too deeply, has alleviateed the whole body damage of anesthesia to the rat simultaneously.
(4) The utility model provides a pair of accurate modeling device who exposes local radiation damage of rat, accurate plumbous system radiation shield that exposes coincide completely with the mount, both can guarantee that the accuracy exposes the position as follows jaw and carry out accurate and the shining of capacity, other non-irradiation area of rat obtain good radiation protection simultaneously.
(5) The utility model provides a pair of accurate modeling device who exposes local radioactive damage of rat, design benefit, simple structure, low cost is worth popularizing and applying in the actual work very much.
Drawings
Fig. 1 is a schematic front structural view of the fixing frame of the present invention.
Fig. 2 is a schematic view of a top surface of the fixing frame according to the present invention.
Fig. 3 is a schematic structural view of the tailbone fixing block of the present invention.
Fig. 4 is a schematic structural diagram of the head fixing block according to the present invention.
Fig. 5 is a schematic structural view of the snap fastener of the present invention.
Fig. 6 is a schematic structural view of the femoral fixing strip according to the present invention.
Fig. 7 is a schematic structural view of the radiation shield of the present invention.
Reference numerals
1 radiation shield
11 radiation port
2 base plate
21 first plate segment
22 second plate section
23 second card slot
3 head baffle
31 first baffle sector
32 second baffle sector
4 head fixing block
41 neck opening
5 limbs fixing plate
51 forelimb opening
52 hind limb opening
53 back opening
54 femoral opening
55 groove
56 first card slot
6 cover plate
7 tail bone fixing block
71 rear opening
8 femur fixing strip
81 snap fastener
9 fastener nail
Detailed Description
The following description is provided for illustrative purposes, and other advantages and features of the present invention will become apparent to those skilled in the art from the following detailed description.
Please refer to fig. 1 to 7. It should be understood that the structure, ratio, size and the like shown in the drawings attached to the present specification are only used for matching with the content disclosed in the specification, so as to be known and read by those skilled in the art, and are not used for limiting the limit conditions that the present invention can be implemented, so that the present invention has no technical essential meaning, and any structure modification, ratio relationship change or size adjustment should still fall within the scope that the technical content disclosed in the present invention can cover without affecting the function that the present invention can produce and the purpose that the present invention can achieve. Meanwhile, the terms such as "upper", "lower", "left", "right", "middle" and "one" used in the present specification are for convenience of description, and are not intended to limit the scope of the present invention, and changes or adjustments of the relative relationship thereof may be made without substantial technical changes, and the present invention is also regarded as the scope of the present invention.
The utility model provides a modeling device of accurate rat local radiation injury that exposes, as shown in figure 1, 2, 7, including following part:
the radiation shield comprises a radiation shield 1, wherein at least one radiation opening 11 is formed in the radiation shield 1;
the fixing frame is sleeved in the radiation shield 1 and comprises a bottom plate 2, and the bottom plate 2 comprises a first plate section 21 and a second plate section 22; a head baffle 3 is arranged on one side of the first plate section 21, and the lower end of the head baffle 3 is connected with the first plate section 21; four-limb fixing plates 5 are respectively arranged on two sides of the second plate section 22, the lower ends of the four-limb fixing plates 5 are connected with the second plate section 22, and the upper ends of the four-limb fixing plates 5 are detachably connected with cover plates 6; a first clamping groove 56 is formed in the inner side wall of one end, close to the first plate section 21, of the four-limb fixing plate 5, and a head fixing block 4 is detachably connected in the first clamping groove 56; and a plurality of second clamping grooves 23 are formed in the second plate section 22, and the tail bone fixing block 7 is detachably connected in the second clamping grooves 23.
In a specific embodiment, the radiation shield 1 is made of lead. Can effectively block the radiation of radioactive substances.
In a specific embodiment, as shown in fig. 7, the radiation shield 1 is a hollow box with two open ends. The radioactive damage of radioactive substances to the rat part without irradiation in the radiation shield 1 can be avoided.
In a preferred embodiment, the thickness of the radiation shield 1 is 3-5mm, preferably 4 mm.
In a preferred embodiment, the length of the radiation shield 1 is 30-40cm, preferably 35 cm; the width of the radiation shield 1 is 6-10cm, preferably 8 cm.
In a preferred embodiment, the length of the radiation opening 11 is 2-3cm, preferably 2.5 cm; the width of the radiation opening 11 is 1-2cm, preferably 1.5 cm.
The radiation port 11 is used to expose a site of a rat to be irradiated with radiation.
In a preferred embodiment, as shown in fig. 1-2, the lower end of the head baffle 3 is connected to the top surface of the first plate section 21, and the head baffle 3 is perpendicular to the first plate section 21.
In a preferred embodiment, the first plate section 21 is 2.0-3.0cm, preferably 2.5cm, higher than the second plate section 22. Because the head of the rat can sink when lying on its side due to the action of gravity, the first plate section 21 below the rat is lifted, so that the head of the rat can be lifted, and the whole body can be kept horizontal.
In a preferred embodiment, as shown in fig. 1, the head baffle 3 includes a first baffle segment 31 and a second baffle segment 32, a wide surface of the second baffle segment 32 is perpendicular to a top surface of the first plate segment 21, and a wide surface of the first baffle segment 31 is parallel to and directly above a top surface of the first plate segment 21. The above-described structure facilitates the securing of the rat head in the region between the first baffle section 31 and the first plate section 21.
The wide surfaces of the first and second baffle segments 31 and 32 are the surfaces of the first and second baffle segments 31 and 32 having the largest area.
In one embodiment, as shown in fig. 2 and 4, the head fixing block 4 is provided with a neck opening 41 at a lower portion thereof. The neck opening 41 has a semicircular shape for catching the neck of the rat to fix the head of the rat.
In a preferred embodiment, as shown in fig. 1-2, the lower end of the limb fixation plate 5 is connected to the side of the second plate segment 22, and the limb fixation plate 5 and the second plate segment 22 are perpendicular to each other.
In a preferred embodiment, the limb fixation plates 5 on both sides of the second plate segment 22 remain symmetrical, as shown in fig. 1.
In a specific embodiment, as shown in fig. 1-2, the limb fixing plate 5 is provided with an anterior limb opening 51, a posterior limb opening 52 and a femoral opening 54; the front limb opening 51, the rear limb opening 52 and the femur opening 53 are located at the lower part of the four-limb fixing plate 5 and are sequentially arranged from near to far away from the first plate section 21, and the upper parts of the four-limb fixing plate 5 arranged at the two sides of the second plate section 22 are matched to form a back opening 53.
The front limb opening 51 is semicircular and used for fixing the front limb of a rat, the rear limb opening 52 is semielliptical and used for fixing the rear limb of the rat, the femur opening 53 is rectangular and used for providing a supporting point for fixing the femur of the rat, and the back opening 54 is elongated and used for exposing the lateral back of the rat.
In one embodiment, as shown in fig. 1-2, the top of the extremity anchoring plate 5 is provided with a plurality of grooves 55. The groove 55 is located on the limb fixation plate 5 below the back opening 53 for providing a binding point for a binding member for fixing a rat. The binding piece is a rope or a rubber band.
In a specific embodiment, as shown in fig. 5, the cover plate 6 is detachably connected to the limb fixation plate 5 via snap pins 9.
In a specific embodiment, as shown in fig. 3, the coccyx fixation block 7 is provided with a tail opening 71. The tail opening 71 is circular for allowing the tail of the rat to penetrate the tail bone fixing block 7, thereby fixing the tail of the rat.
In a specific embodiment, as shown in fig. 6, the fixation frame further comprises a femoral fixation strip 8, wherein the femoral fixation strip 8 is provided with a plurality of snap fasteners 81, and the femoral fixation strip 8 is looped through the femoral opening 54 via the snap fasteners 81.
The following describes a specific application process of the modeling apparatus for accurately exposing local radiation injury of a rat according to the present invention with reference to fig. 1 to 7.
When a user obtains a modeling device for accurately exposing local radioactive injuries of rats as shown in fig. 1-7, 1 male SD rat of about 350g is randomly selected, is anesthetized by intraperitoneal injection by using a 1% sodium pentobarbital solution (10mg/kg), and is placed in the modeling device for fixation. Namely, a rat is placed on the bottom plate 2, the head of the rat is arranged on the first plate section 21 and leans against the head baffle plate 3, the head fixing block 4 is inserted into the neck of the rat through the first clamping groove 56, the neck of the rat is clamped, so that the head of the rat is fixed, and meanwhile, the head of the rat is fixed in the area between the first baffle plate section 31 and the first plate section 21 through the first baffle plate section 31 protruding from the head baffle plate 3. Because the head of the rat can sink when lying on its side due to the action of gravity, the first plate section 21 below the rat is lifted, the first plate section 21 is higher than the second plate section 22 by 2.5cm, the head is lifted, and the body is kept horizontal.
Then, the front limb of the rat is protruded out of the limb fixing plate 5 through the front limb opening 51, thereby fixing the front limb of the rat. The hind limbs of the rat are extended out of the limb fixing plate 5 through the hind limb opening 52, thereby fixing the hind limbs of the rat. According to the volume of the rat, the tail of the rat is inserted into the tail bone fixing block 7 through the different second clamping grooves 23, and the tail of the rat penetrates through the tail opening 71 on the tail bone fixing block 7, so that the tail of the rat is fixed. Cover the cover plate 6, and detachably connect the cover plate 6 and the four-limb fixing plate 5 through the snap nails 9. The rat can also be fixated using the femoral fixation strip 8 looped through the femoral opening 54 via snap 81.
When the size of the rat is large, the rat can be fixed by diagonally binding the rat through the groove 55 on the limb fixing plate 5 by using the disposable rubber band. Meanwhile, the tibia of the rat can be simply wound and fixed by a rubber ring.
The rat fixed on the fixed frame is sleeved in the radiation shield 1, and different parts of the rat are irradiated through the radiation port 11 on the radiation shield 1. For example, exposure of 2.5 x 1.5cm of the exposed area of the rat mandible was performed, and for example, exposure of the rat femur on the outside of a lead cap was performed.
To sum up, the utility model provides a pair of accurate modeling device who exposes local radioactive damage of rat, design benefit both can guarantee that the accuracy exposes the mandible and carry out accurate and the irradiation of capacity, and other non-irradiation area of rat obtain good radiation protection simultaneously. Therefore, the utility model effectively overcomes various defects in the prior art and has high industrial utilization value.
The above embodiments are merely illustrative of the principles and effects of the present invention, and are not to be construed as limiting the invention. Modifications and variations can be made to the above-described embodiments by those skilled in the art without departing from the spirit and scope of the present invention. Accordingly, it is intended that all equivalent modifications or changes which may be made by those skilled in the art without departing from the spirit and technical spirit of the present invention be covered by the claims of the present invention.
Claims (8)
1. A modeling device for accurately exposing a local radioactive injury of a rat is characterized by comprising a radiation shield (1) and a fixing frame, wherein at least one radiation opening (11) is formed in the radiation shield (1); the fixing frame is sleeved in the radiation shield (1), the fixing frame comprises a bottom plate (2), and the bottom plate (2) comprises a first plate section (21) and a second plate section (22); a head baffle (3) is arranged on one side of the first plate section (21), and the lower end of the head baffle (3) is connected with the first plate section (21); four-limb fixing plates (5) are respectively arranged on two sides of the second plate section (22), the lower ends of the four-limb fixing plates (5) are connected with the second plate section (22), and the upper ends of the four-limb fixing plates (5) are detachably connected with cover plates (6); a first clamping groove (56) is formed in the inner side wall of one end, close to the first plate section (21), of the four-limb fixing plate (5), and a head fixing block (4) is detachably connected in the first clamping groove (56); the second plate section (22) is provided with a plurality of second clamping grooves (23), and the tail bone fixing blocks (7) are detachably connected in the second clamping grooves (23).
2. The modeling apparatus for accurately exposing local radioactive damage of rat according to claim 1, wherein the head baffle (3) comprises a first baffle section (31) and a second baffle section (32), a wide surface of the second baffle section (32) is perpendicular to a top surface of the first plate section (21), and a wide surface of the first baffle section (31) is parallel to the top surface of the first plate section (21) and is located right above the top surface of the first plate section (21).
3. The modeling device for the precise exposure of the local radioactive injury of the rat according to claim 1, wherein the lower part of the head fixing block (4) is provided with a neck opening (41).
4. The modeling device for the precise exposure of the local radioactive injury of the rat according to claim 1, wherein the limb fixing plate (5) is provided with a forelimb opening (51), a hindlimb opening (52) and a femur opening (54); the forelimb opening (51), the hindlimb opening (52) and the femur opening (54) are positioned at the lower part of the four-limb fixing plate (5) and are sequentially arranged from near to far away from the first plate section (21); the upper parts of the four-limb fixing plates (5) arranged on the two sides of the second plate section (22) are matched to form a back opening (53).
5. The modeling apparatus for accurately exposing local radioactive injury of rat according to claim 4, wherein the top of the extremity fixing plate (5) is provided with a plurality of grooves (55).
6. The modeling device for accurately exposing partial radioactive injury of rat according to claim 1, wherein the cover plate (6) is detachably connected with the extremity fixing plate (5) through a snap nail (9).
7. The modeling apparatus for accurately exposing local radioactive damage of rat according to claim 1, wherein the tailbone fixing block (7) is provided with a tail opening (71).
8. The modeling device for the precise exposure of the local radiation injury of the rat according to claim 1, wherein the fixing frame further comprises a femur fixing strip (8), the femur fixing strip (8) is provided with a plurality of snap fasteners (81), and the femur fixing strip (8) penetrates through the femur opening (54) and is looped through the snap fasteners (81).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021544827.6U CN213220559U (en) | 2020-07-30 | 2020-07-30 | Modeling device for accurately exposing local radioactive damage of rat |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021544827.6U CN213220559U (en) | 2020-07-30 | 2020-07-30 | Modeling device for accurately exposing local radioactive damage of rat |
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| CN213220559U true CN213220559U (en) | 2021-05-18 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115006742A (en) * | 2022-06-01 | 2022-09-06 | 中国人民解放军空军军医大学 | Fixed shielding device for mouse head ray irradiation |
-
2020
- 2020-07-30 CN CN202021544827.6U patent/CN213220559U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115006742A (en) * | 2022-06-01 | 2022-09-06 | 中国人民解放军空军军医大学 | Fixed shielding device for mouse head ray irradiation |
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