CN213210102U - Asynchronous disintegration time limit tester - Google Patents
Asynchronous disintegration time limit tester Download PDFInfo
- Publication number
- CN213210102U CN213210102U CN202022066417.1U CN202022066417U CN213210102U CN 213210102 U CN213210102 U CN 213210102U CN 202022066417 U CN202022066417 U CN 202022066417U CN 213210102 U CN213210102 U CN 213210102U
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- Prior art keywords
- water bath
- asynchronous
- beaker
- bath tank
- disintegration time
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 61
- 238000010438 heat treatment Methods 0.000 claims abstract description 16
- 238000006243 chemical reaction Methods 0.000 claims abstract description 15
- 230000005540 biological transmission Effects 0.000 claims description 3
- 239000003814 drug Substances 0.000 abstract description 15
- 238000002474 experimental method Methods 0.000 abstract description 12
- 238000001514 detection method Methods 0.000 abstract description 5
- 229940079593 drug Drugs 0.000 description 9
- 238000000034 method Methods 0.000 description 7
- 239000007864 aqueous solution Substances 0.000 description 5
- 238000004090 dissolution Methods 0.000 description 5
- 239000000243 solution Substances 0.000 description 4
- 230000002159 abnormal effect Effects 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 238000000429 assembly Methods 0.000 description 2
- 230000000712 assembly Effects 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000008298 dragée Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000003028 elevating effect Effects 0.000 description 1
- 239000002662 enteric coated tablet Substances 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000007941 film coated tablet Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000008236 heating water Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000007940 sugar coated tablet Substances 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses an asynchronous formula time limit tester that disintegrates, include: the device comprises a console, a case, a water bath tank and a base; the console is arranged above the case, the water bath box is arranged inside the case, and the base is arranged below the case; a heating device and a plurality of reaction components are arranged in the water bath tank, each reaction component comprises a beaker, a hanging basket and a lifting device, and the beaker is fixedly arranged in the water bath tank; the upper end of the lifting device is hung with a hanging basket, and the lifting device drives the hanging basket to move up and down in the beaker. Therefore, the utility model discloses can support a plurality of experiments to go on, simple high-efficient, contrast nature is strong, has solved the problem that only supports a set of experiment among the prior art, the utility model discloses to the detection of batch medicine more save time, high-efficient, provide more flexibility and multifunctionality.
Description
Technical Field
The utility model belongs to the technical field of disintegration time limit tester technique and specifically relates to an asynchronous formula disintegration time limit tester.
Background
As is well known, a disintegration time tester is used for testing the disintegration time of a drug such as a tablet, a sugar-coated tablet, a film-coated tablet, an enteric-coated tablet, an extract tablet, or a capsule of a solid pharmaceutical preparation, and is used for examining the disintegration of the solid pharmaceutical preparation under predetermined conditions.
It has been pointed out as early as decades that the rate of absorption of a drug in the body is often determined by the rate of dissolution, and that a drug in a solid formulation must undergo disintegration and dissolution before being absorbed and then be converted to a solution, and that if the drug is not readily released from the formulation or the rate of dissolution of the drug is extremely slow, the rate or extent of absorption of the drug in the formulation may be problematic. Moreover, some drugs with severe pharmacological action and small safety index can cause obvious adverse reaction if the dissolution speed of the drug which is absorbed rapidly is too fast, and the time for maintaining the drug effect is shortened, under the condition, the dissolution rate of the drug in the preparation is required to be controlled.
The existing disintegration time limit tester has single form and function, can not simultaneously operate a plurality of groups of experiments, has poor contrast and greatly influences the test process and efficiency.
Based on this, designing a disintegration time tester capable of supporting multiple groups of experiments is an urgent problem to be solved by those skilled in the art.
SUMMERY OF THE UTILITY MODEL
The utility model provides an asynchronous formula time limit tester that disintegrates for only can support the problem of singly organizing the experiment that exists among the solution prior art, realized the multiunit experiment of concurrent operation, simple high-efficient, accelerated process, the efficiency of experiment, the time of having practiced thrift, the utility model discloses to the detection of batch medicine more save time, high-efficient, provide more flexibility and multifunctionality.
The utility model provides a its technical problem take following technical scheme to realize:
the embodiment of the invention provides an asynchronous disintegration time limit tester, which comprises: the device comprises a console, a case, a water bath tank and a base;
the console is arranged above the case, the water bath box is arranged inside the case, and the base is arranged below the case;
a heating device and a plurality of reaction components are arranged in the water bath tank, each reaction component comprises a beaker, a hanging basket and a lifting device, and the beaker is fixedly arranged in the water bath tank;
the hanging basket is hung at the upper end of the lifting device, and the lifting device drives the hanging basket to enable the hanging basket to move up and down in the beaker.
Optionally, in an embodiment of the present invention, the lifting device includes: the lifting device comprises a motor, a motor shaft, a cam, a lifting shaft and a fixing frame;
the motor is connected with the motor shaft through a coupler, the motor shaft is fixedly connected with the cam, the cam is in transmission connection with the lifting shaft, and the motor is fixedly arranged on the fixing frame.
Optionally, in the embodiment of the present invention, the chassis further includes a machine leg, and the machine leg is disposed below the chassis.
Optionally, in the embodiment of the present invention, a water pump is disposed in the water bath tank.
Optionally, in the embodiment of the utility model provides an in the water bath box below level is provided with the fixed plate, the fixed camera that sets up on the fixed plate, the camera is just to in the water bath box the bottom of beaker.
Optionally, in the embodiment of the present invention, the console, the case, the water bath box, the frame and the machine legs are integrally connected.
Optionally, in an embodiment of the present invention, the heating device includes: a temperature sensor, a heater, and a controller;
the temperature sensor and the heater are fixedly arranged in the water bath box; the controller is fixedly arranged at the top of the water bath tank;
the temperature sensor and the heater are respectively electrically connected with the controller.
The utility model has the advantages that:
first, the utility model discloses can support a plurality of experiments to go on, solve the problem that only supports a set of experiment among the prior art, simple high-efficient, contrast nature is strong, to the detection of batch medicine more save time, high-efficient, provide more flexibility and multifunctionality.
Secondly, the operator can set the disintegration time and the disintegration temperature by operating the keys on the console, thereby realizing intelligent control.
And thirdly, the motor drives the cam to rotate, and the cam drives the lifting rod to drive the hanging basket to move up and down, so that the hanging basket enters the beaker at any time, the manual operation of an operator is not needed in the process, and the workload of the operator is reduced.
Fourthly, a water pump is arranged in the water bath tank, so that the water circulation flow in the water bath tank can be promoted, and meanwhile, when the water in the water bath tank is heated, the heating speed is high and the heating is uniform.
Fifthly, in the operation process, an operator can complete recording through the camera, so that follow-up checking at any time is facilitated, and the record is convenient to store.
Sixth, in the present invention, since the water bath box is of a transparent structure, the operator can observe the conditions inside the water bath box at any time.
Drawings
Fig. 1 is a front view of an asynchronous disintegration time limit tester provided by the present invention;
fig. 2 is a side partial sectional view of an asynchronous disintegration time limit tester provided by the present invention;
fig. 3 is a cross-sectional view of a lifting device provided by the present invention;
fig. 4 is a schematic view of the connection relationship between the motor, the motor shaft, the cam and the lifting shaft provided by the present invention;
fig. 5 is a side partial sectional view of a heating device provided by the utility model;
reference numerals:
1. a console; 2. a chassis; 3. a water bath tank; 4. a machine base; 5. a heating device; 6. a reaction assembly; 7. a beaker; 8. a hanging basket; 9. a lifting device; 10. a motor; 11. a motor shaft; 12. a cam; 13. a lifting shaft; 14. a fixed mount; 15 machine legs; 16. a temperature sensor; 17. a heater; 18. and a controller.
Detailed Description
The embodiments of the present invention will be described in detail with reference to the accompanying drawings:
the invention provides an asynchronous disintegration time tester, as shown in figures 1 and 2, comprising: the device comprises a console 1, a case 2, a water bath tank 3 and a machine base 4;
the console 1 is arranged above the case 2, the water bath tank 3 is arranged inside the case 2, and the base 4 is arranged below the case 2;
a heating device 5 and a plurality of reaction components 6 are arranged in the water bath tank 3, each reaction component 6 comprises a beaker 7, a hanging basket 8 and a lifting device 9, and the beaker 7 is fixedly arranged in the water bath tank 3;
the upper end of the lifting device 9 is hung with the hanging basket 8, and the lifting device 9 drives the hanging basket 8 to move the hanging basket 8 up and down in the beaker 7.
The number of the reaction assemblies 6 can be set to be 2, 3 or 4, and the reaction assemblies can be set according to actual conditions, and are not specifically limited, so that the design flexibility is improved, and the requirements of different scenes are met.
The container provided inside the water bath tank may be, but is not limited to, the beaker 7, and may be another container such as a glass, and is not limited thereto.
To explain this point, before using the disintegration time tester, the water bath 3 needs to be cleaned in order to remove impurities, and when an aqueous solution is subsequently added to the water bath 3, the purity of the aqueous solution can be ensured and the impurities are prevented from being mixed in the aqueous solution.
It is emphasized that the elevation height of the elevation means 9 in each reaction block 6 may be the same, that is, the baskets 8 in each reaction block 6 enter the beaker 7 simultaneously; of course, the lifting height of the lifting device 9 in each reaction assembly 6 can also be different, that is, the baskets 8 in each reaction assembly 6 enter the beaker 7 asynchronously, which can be determined according to the actual situation.
Therefore, the utility model discloses can support a plurality of experiments to go on, simple high-efficient, contrast nature is strong, has solved the problem that only supports a set of experiment among the prior art, the utility model discloses to the detection of batch medicine more save time, high-efficient, provide more flexibility and multifunctionality.
Optionally, in an embodiment of the present invention, as shown in fig. 2, fig. 3, fig. 4, and fig. 5, the lifting device 9 includes: a motor 10, a motor shaft 11, a cam 12, a lifting shaft 13 and a fixing frame 14;
the motor 10 is connected with a motor shaft 11 through a coupler, the motor shaft 11 is fixedly connected with a cam 12, the cam 12 is in transmission connection with a lifting shaft 13, and the motor 10 is fixedly arranged on a fixed frame 14.
So, drive hanging flower basket 8 through elevating gear 9 and reciprocate for hanging flower basket 8 gets into beaker 7 at any time, and this process need not operating personnel manual operation, has reduced staff's work load.
Optionally, in the embodiment of the present invention, the chassis further includes a chassis 15, and the chassis 15 is disposed below the chassis 2.
Wherein, the chassis 15 is provided with four altogether, and four chassis 15 install respectively in four corners of frame 4, so, has strengthened the stability of disintegration time limit tester.
Optionally, in the embodiment of the present invention, a water pump is disposed in the water bath tank 3.
Wherein, the purpose that is provided with the water pump in water bath 3 is: the water pump can promote the flow of the aqueous solution in the water bath 3, the aqueous solution in the heating device 5 heating water bath 3, the heating speed is high, the heating is even, and the process of the experiment is accelerated.
Optionally, the embodiment of the present invention provides a fixing plate horizontally disposed below the water bath box 3, a camera is fixedly disposed on the fixing plate, and the camera is aligned with the bottom of the beaker 7 in the water bath box 3.
Wherein, the camera can be through fixed the setting on the fixed plate of bolt, nut, and the camera just to the bottom of beaker 7 in the water bath 3, can monitor the real-time condition of hanging flower basket 8, and clear, audio-visual specific time that obtains the medicine and disintegrate is convenient for remain data after the medicine test, is favorable to follow-up looking over at any time.
Optionally, in the embodiment of the present invention, the console 1, the cabinet 2, the water bath box 3, the frame 4, and the legs 15 are integrally connected.
It should be noted that the water bath tank 3 can be made of transparent material, so as to facilitate the operator to observe the water level inside the water bath tank 3, and to monitor the experimental conditions in real time.
Optionally, in the embodiment of the present invention, the console 1 may include:
the temperature control device comprises a temperature indicator light, an abnormal indicator light, a display window, a starting control key, a temperature preset key, a timing preset key and a temperature control key.
The function of the above-described keys will be explained in detail as follows:
the temperature control indicator lamp is an indicator lamp for displaying the working state of the system. When the temperature control indicator light is on, the system is in an automatic temperature control state; when the temperature control indicator light is turned off, the system is in a non-temperature control state.
In addition, the disintegration time limit detector has the detection and diagnosis functions, so when the disintegration time limit detector detects a fault, the red abnormal indicating lamp is lightened to prompt an operator, a large amount of time is saved for the operator to find an abnormal part, and accidents are avoided.
The display window is used for displaying time and temperature, so that an operator can conveniently check and record data;
the start control key is used for controlling the disintegration time limit tester to be opened or closed;
the temperature presetting key is pressed by an operator to set temperature parameters;
the timing preset key is pressed by an operator, and a time parameter can be set;
the temperature control button is used for controlling the temperature control function, and an operator can turn on or turn off the temperature control function by clicking the temperature control button.
It should be noted that the console 1 is not limited to include the above mentioned keys, and may include other keys, which are not specifically limited herein, to improve the flexibility of the design.
Optionally, in an embodiment of the present invention, the heating device 5 includes: a temperature sensor 16, a heater 17, and a controller 18;
a temperature sensor 16 and a heater 17 are fixedly arranged in the water bath tank 3; the top of the water bath tank 3 is fixedly provided with a controller 18;
the temperature sensor 16 and the heater 17 are electrically connected to a controller 18, respectively.
Wherein the heater 17 in the heating device 5 is used for heating the water solution in the water bath 3, and the temperature sensor is used for detecting the current real-time temperature, and generally, the water temperature is controlled to be 37 ℃ ± 2 ℃, for example, the water temperature can be, but is not limited to, 37.1 ℃.
It should be emphasized that the embodiments of the present invention are illustrative and not restrictive, and therefore the present invention is not limited to the embodiments in the specific embodiments, and all other embodiments derived from the technical solutions of the present invention by those skilled in the art also belong to the protection scope of the present invention.
Claims (6)
1. An asynchronous disintegration time limit tester, comprising: a console (1), a case (2), a water bath tank (3) and a machine base (4);
the console (1) is arranged above the case (2), the water bath tank (3) is arranged inside the case (2), and the base (4) is arranged below the case (2);
a heating device (5) and a plurality of reaction components (6) are arranged in the water bath box (3), each reaction component (6) comprises a beaker (7), a hanging basket (8) and a lifting device (9), and the beaker (7) is fixedly arranged in the water bath box (3);
the hanging basket (8) is hung at the upper end of the lifting device (9), and the lifting device (9) drives the hanging basket (8) to enable the hanging basket (8) to move up and down in the beaker (7);
the lifting device (9) comprises: the device comprises a motor (10), a motor shaft (11), a cam (12), a lifting shaft (13) and a fixed frame (14);
the motor (10) is connected with the motor shaft (11) through a coupler, the motor shaft (11) is fixedly connected with the cam (12), the cam (12) is in transmission connection with the lifting shaft (13), and the motor (10) is fixedly arranged on the fixed frame (14).
2. The asynchronous disintegration time tester of claim 1, further comprising a stand (15), wherein the stand (15) is disposed under the cabinet (2).
3. The asynchronous disintegration time tester of claim 1, wherein a water pump is disposed in the water bath (3).
4. The asynchronous disintegration time tester of claim 1, wherein a fixed plate is horizontally arranged below the water bath tank (3), and a camera is fixedly arranged on the fixed plate and directly faces the bottom of the beaker (7) in the water bath tank (3).
5. The asynchronous disintegration time tester of claim 2, wherein the console (1), the chassis (2), the water bath tank (3), the base (4), and the legs (15) are integrally connected.
6. An asynchronous disintegration time tester according to claim 1, characterised in that said heating means (5) comprises: a temperature sensor (16), a heater (17), and a controller (18);
the temperature sensor (16) and the heater (17) are fixedly arranged in the water bath tank (3); the controller (18) is fixedly arranged at the top of the water bath tank (3);
the temperature sensor (16) and the heater (17) are respectively electrically connected with the controller (18).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202022066417.1U CN213210102U (en) | 2020-09-21 | 2020-09-21 | Asynchronous disintegration time limit tester |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN202022066417.1U CN213210102U (en) | 2020-09-21 | 2020-09-21 | Asynchronous disintegration time limit tester |
Publications (1)
Publication Number | Publication Date |
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CN213210102U true CN213210102U (en) | 2021-05-14 |
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CN202022066417.1U Expired - Fee Related CN213210102U (en) | 2020-09-21 | 2020-09-21 | Asynchronous disintegration time limit tester |
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CN (1) | CN213210102U (en) |
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2020
- 2020-09-21 CN CN202022066417.1U patent/CN213210102U/en not_active Expired - Fee Related
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GR01 | Patent grant | ||
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CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210514 |