CN213141894U - Antibody sample extraction element for antibody recombination - Google Patents
Antibody sample extraction element for antibody recombination Download PDFInfo
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- CN213141894U CN213141894U CN202021455047.4U CN202021455047U CN213141894U CN 213141894 U CN213141894 U CN 213141894U CN 202021455047 U CN202021455047 U CN 202021455047U CN 213141894 U CN213141894 U CN 213141894U
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- antibody
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- sample extraction
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Abstract
The utility model discloses an antibody sample extraction element is used in antibody reorganization, include box, case lid, division board, store storehouse, utensil storehouse and abandonment storehouse. This antibody sample extraction element is used in antibody reorganization, during the use, at first put the position that needs to use through the bolster with the device, then take off the case lid from the box top, make the box opened, then operating personnel takes the pipettor from the utensil storehouse and draws the antibody sample of having cultivated, then unscrew the screw cap at storage box top, make the storage box opened, then take the storage vessel from the protection sponge in the storage box, then transfer the antibody sample that the pipettor was drawn into in the storage vessel, then put the storage vessel in the protection sponge again, then put the abandonment storehouse from the dog-house that the storehouse was covered with the pipettor, then operating personnel twists the screw cap at the top of storage box again, make the storage box sealed, then operating personnel take the case lid and put on the box again.
Description
Technical Field
The utility model relates to an antibody field specifically is an antibody sample extraction element for antibody recombination.
Background
The recombinant antibody, also called as a genetic engineering antibody, refers to an antibody obtained by transforming and recombining the corresponding gene sequence of the antibody as required by a DNA recombination technology, constructing the recombinant antibody on a plasmid, and transfecting/transforming the constructed plasmid into a suitable host cell to express the recombinant antibody by a protein exogenous expression technology. The recombinant antibody well solves the problem of human rejection caused by animal source antibodies, enables the antibody to realize humanization, enables the efficiency of the antibody to be more complete, and the antibody preparation technology goes through three stages, namely a first stage, the antibody is obtained by purifying the serum of animals through high-grade animals immunized by antigens, and the antibody is a polyclonal antibody; in the second stage, hybridoma technology was developed to produce monoclonal antibodies against a single epitope by fusing immortal myeloma cells with antibody-producing B lymphocytes; and in the third stage, the gene sequence of the monoclonal antibody produced by animals is modified by a gene engineering technology, so that the performance of the monoclonal antibody is more in line with the application requirement and can be obtained by large-scale cell culture, and the antibody in the stage is a recombinant antibody.
The antibody sample for antibody recombination is extracted, namely, the cultured antibody is transferred to a storage vessel through a syringe to wait for the next processing, but the operation tools are placed in a mess manner in the existing extraction mode, so that the working efficiency of operators is influenced.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an antibody sample extraction element is used in antibody recombination to solve the problem that proposes in the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme:
the utility model provides an antibody sample extraction element for antibody reorganization, the power distribution box comprises a box body, the equal fixed mounting in ground dead angle of box has the pad foot, the top surface magnetism of box is connected with the case lid, the inner wall fixedly connected with T shape division board of box, the utensil storehouse is cut apart into with the box to T shape division board, abandonment storehouse and storage storehouse, be equipped with the pipettor in the utensil storehouse, the top in abandonment storehouse is equipped with the cang gai, the dog-house that is linked together with abandonment storehouse is seted up to the top surface of cang gai, the bottom surface symmetry fixedly connected with axle bed of cangai, the inboard rotation of axle bed is connected with the pivot, the axle bed is all passed at the both ends of pivot and the cover is equipped with reset spring, reset spring's one end fixed connection is on the outer wall of pivot, reset spring's.
As a further aspect of the present invention: the low-temperature storage mechanism comprises a mobile power supply, a heat preservation shell, a storage box, a refrigerating sheet, a heat dissipation grid, a threaded cover, a switch, a protective sponge and a storage vessel.
As a further aspect of the present invention: the bin is arranged on one side of the inside of the storage bin, the bin is fixedly connected to the bottom of the box body, and the bottom surface of the bin penetrates through the bottom surface of the box body and is flush with the bottom surface of the box body.
As a further aspect of the present invention: refrigeration piece fixed mounting is in the bottom surface of bin, and heat dissipation grid fixed connection is in the bottom surface of refrigeration piece, and the hot side of refrigeration piece is towards heat dissipation grid, and the cold side of refrigeration piece is towards the bin.
As a further aspect of the present invention: the fixed cover of heat preservation casing is established in the outside of bin, is equipped with the protection sponge in the bin, is equipped with storage household utensils in the protection sponge, and threaded connection has the screw cap in the top memory of bin.
As a further aspect of the present invention: the portable power source is arranged on the other side of the interior of the storage bin, the portable power source is fixedly arranged at the bottom of the box body, and the switch is fixedly arranged on the top surface of the portable power source.
As a further aspect of the present invention: the refrigeration piece and the switch are both electrically connected with the mobile power supply through the switch.
Compared with the prior art, the beneficial effects of the utility model are that:
1. the utility model discloses a box, the foot pad case lid, T shape division board, the utensil storehouse, abandonment storehouse, the cooperation of storing between the storehouse is used, make the antibody sample draw the utensil that uses by classified storage, through the cang gai, the dog-house, the axle bed, the apparatus further comprises a rotating shaft, cooperation between reset spring and the shrouding is used, make the dog-house of putting into waste material and sealing abandonment storehouse that abandonment storehouse can be convenient, make the box inside cleaner, thereby make that this device can be convenient mention the utensil to the antibody sample and store, arrange in order and categorised, make things convenient for operating personnel to take and put.
2. The utility model discloses a portable power source, heat preservation casing, bin, refrigeration piece, heat dissipation grid, screw cap, switch, protection sponge and the cooperation between the storage household utensils are used for the device can be built the low temperature environment through the refrigeration piece and carry out the low temperature to the antibody sample and preserve, and the protection sponge provides support and protection for the storage household utensils simultaneously, thereby makes this device have cooling function, can be better store the antibody.
Drawings
FIG. 1 is a schematic diagram showing an exploded structure of an antibody sample extraction apparatus for antibody reconstitution.
FIG. 2 is an enlarged view of A in an antibody sample-extracting apparatus for antibody reconstitution.
FIG. 3 is a schematic view showing an open structure of an antibody sample-extracting apparatus for antibody reconstitution.
FIG. 4 is a side sectional view of an antibody sample-extracting apparatus for antibody reconstitution.
In the figure: the device comprises a box body 1, a foot pad 2, a box cover 3, a T-shaped partition plate 4, an appliance bin 5, a waste bin 6, a storage bin 7, a bin cover 8, a feed opening 9, a shaft seat 10, a rotating shaft 11, a return spring 12, a sealing plate 13, a low-temperature storage mechanism 14, a mobile power supply 15, a heat-preservation shell 16, a storage bin 17, a refrigerating sheet 18, a heat dissipation grid 19, a threaded cover 20, a switch 21, a protective sponge 22 and a storage vessel 23.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1 to 3, in an embodiment of the present invention, an antibody sample extraction device for antibody recombination includes a box body 1, a pad 2 is fixedly installed at a dead angle on the ground of the box body 1, a box cover 3 is magnetically connected to the top surface of the box body 1, a T-shaped partition plate 4 is fixedly connected to the inner wall of the box body 1, the box body 1 is divided into an instrument bin 5, a waste bin 6 and a storage bin 7 by the T-shaped partition plate 4, a pipettor is installed in the instrument bin 5, a bin cover 8 is installed at the top of the waste bin 6, a feeding port 9 communicated with the waste bin 6 is installed at the top surface of the bin cover 8, a shaft seat 10 is symmetrically and fixedly connected to the bottom surface of the bin cover 8, a rotating shaft 11 is rotatably connected to the inner side of the shaft seat 10, both ends of the rotating shaft 11 pass through the shaft seat 10 and are sleeved with a return spring 12, the outer wall fixedly connected with shrouding 13 of pivot 11, shrouding 13 and dog-house 9 are to and the adaptation, store and be equipped with low temperature in the storehouse 7 and store mechanism 14.
The low-temperature storage mechanism 14 comprises a mobile power supply 15, a heat preservation shell 16, a storage box 17, a refrigerating sheet 18, a heat dissipation grid 19, a threaded cover 20, a switch 21, a protective sponge 22 and a storage vessel 23.
The storage box 17 is arranged on one side of the inside of the storage bin 7, the storage box 17 is fixedly connected to the bottom of the box body 1, and the bottom surface of the storage box 17 penetrates through the bottom surface of the box body 1 to be flush with the bottom surface of the box body 1.
The refrigeration piece 18 is fixedly installed on the bottom surface of the storage box 17, the heat dissipation grid 19 is fixedly connected on the bottom surface of the refrigeration piece 18, the hot surface of the refrigeration piece 18 faces the heat dissipation grid 19, and the cold surface of the refrigeration piece 18 faces the storage box 17.
The heat preservation shell 16 is fixedly sleeved on the outer side of the storage box 17, a protective sponge 22 is arranged in the storage box 17, a storage vessel 23 is arranged in the protective sponge 22, and a threaded cover 20 is in threaded connection with the top of the storage box 17.
As a further aspect of the present invention: portable power source 15 establishes the inside opposite side of storing storehouse 7, and portable power source 15 fixed mounting is in the bottom of box 1, and switch 21 fixed mounting is on portable power source 15's top surface.
The refrigeration sheet 18 and the switch 21 are both electrically connected with the mobile power supply 15 through the switch.
The utility model discloses a theory of operation is:
when the device is used, the device is placed at a position to be used through the pad 2, the box cover 3 is taken down from the top of the box body 1, the box body 1 is opened, the mobile power supply 15 is controlled through the switch 21 to supply power to the refrigerating sheet 18, the refrigerating sheet 18 starts to work at the moment, the refrigerating sheet 18 starts to conduct heat to cool the storage box 17 and the inner space of the storage box 17, a low-temperature environment is created inside the storage box 17, meanwhile, the refrigerating sheet 18 distributes heat energy generated by the refrigerating sheet 18 through the heat dissipation grid 19 to maintain the running state of the refrigerating sheet 18, the heat insulation shell 16 conducts temperature separation on the storage box 17 at the moment to avoid loss of cold energy in the storage box 17, then an operator takes the pipettor from the appliance bin 5 to absorb a cultured antibody sample, then unscrews the threaded cover 20 at the top of the storage box 17 to open the storage box 17, and then takes the storage vessel 23 from the protective sponge 22 in the storage box 17, then transfer the antibody sample that the pipettor sucked to in storing household utensils 23, then put storing household utensils 23 in protection sponge 22 again, then put the pipettor into abandonment storehouse 6 from dog-house 9 on the cang gai 8, the pipettor produced the extrusion to shrouding 13 this moment, make shrouding 13 rotate on axle bed 10 through pivot 11, thereby dog-house 9 is opened, then the pipettor drops to enter into abandonment storehouse 6 and is stored, pivot 11 drives shrouding 13 and resets again under reset spring 12's effect at this moment and seal dog-house 9, then operating personnel twists threaded cover 20 at the top of storage box 17 again, make storage box 17 sealed, then operating personnel takes case lid 3 to place on box 1 again, case lid 3 magnetic connection is on box 1 this moment, make box 1 sealed, finish the sample and draw the worker to make this moment.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Claims (7)
1. The utility model provides an antibody sample extraction element for antibody recombination, includes box (1), its characterized in that: the device is characterized in that the ground dead corners of the box body (1) are fixedly provided with pad feet (2), the top surface of the box body (1) is magnetically connected with a box cover (3), the inner wall of the box body (1) is fixedly connected with a T-shaped partition plate (4), the box body (1) is divided into an appliance bin (5), a waste bin (6) and a storage bin (7) by the T-shaped partition plate (4), a pipettor is arranged in the appliance bin (5), the top of the waste bin (6) is provided with a bin cover (8), the top surface of the bin cover (8) is provided with a feed opening (9) communicated with the waste bin (6), the bottom surface of the bin cover (8) is symmetrically and fixedly connected with a shaft seat (10), the inner side of the shaft seat (10) is rotatably connected with a rotating shaft (11), two ends of the rotating shaft (11) penetrate through the shaft seat (10) and are sleeved with a return spring (12), one end of the return spring (12) is, the outer wall fixedly connected with shrouding (13) of pivot (11), shrouding (13) and dog-house (9) are to and the adaptation, store and be equipped with low temperature in the storehouse (7) and store mechanism (14).
2. The antibody sample extraction device for antibody reconstitution according to claim 1, wherein: the low-temperature storage mechanism (14) comprises a mobile power supply (15), a heat preservation shell (16), a storage box (17), a refrigeration sheet (18), a heat dissipation grid (19), a threaded cover (20), a switch (21), a protection sponge (22) and a storage vessel (23).
3. The antibody sample extraction device for antibody reconstitution according to claim 2, wherein: bin (17) are established in the inside one side of storing storehouse (7), and bin (17) fixed connection is in the bottom of box (1), and the bottom surface of bin (17) passes the bottom surface of box (1) and flushes with the bottom surface of box (1).
4. The antibody sample extraction device for antibody reconstitution according to claim 2, wherein: refrigeration piece (18) fixed mounting is in the bottom surface of bin (17), and heat dissipation grid (19) fixed connection is in the bottom surface of refrigeration piece (18), and the hot side of refrigeration piece (18) is towards heat dissipation grid (19), and the cold side of refrigeration piece (18) is towards bin (17).
5. The antibody sample extraction device for antibody reconstitution according to claim 2, wherein: the heat preservation shell (16) is fixedly sleeved on the outer side of the storage box (17), a protective sponge (22) is arranged in the storage box (17), a storage vessel (23) is arranged in the protective sponge (22), and a threaded cover (20) is in threaded connection with the top of the storage box (17).
6. The antibody sample extraction device for antibody reconstitution according to claim 2, wherein: portable power source (15) are established at the inside opposite side of storing storehouse (7), portable power source (15) fixed mounting in the bottom of box (1), and switch (21) fixed mounting is in portable power source (15)'s top surface.
7. The antibody sample extraction device for antibody reconstitution according to claim 2, wherein: the refrigeration piece (18) and the switch (21) are electrically connected with the mobile power supply (15) through the switch.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021455047.4U CN213141894U (en) | 2020-07-22 | 2020-07-22 | Antibody sample extraction element for antibody recombination |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021455047.4U CN213141894U (en) | 2020-07-22 | 2020-07-22 | Antibody sample extraction element for antibody recombination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN213141894U true CN213141894U (en) | 2021-05-07 |
Family
ID=75732425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021455047.4U Active CN213141894U (en) | 2020-07-22 | 2020-07-22 | Antibody sample extraction element for antibody recombination |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN213141894U (en) |
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2020
- 2020-07-22 CN CN202021455047.4U patent/CN213141894U/en active Active
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