CN212996863U

CN212996863U - Device for establishing extrusion syndrome animal model

Info

Publication number: CN212996863U
Application number: CN202020769928.7U
Authority: CN
Inventors: 孙学东; 董春晓; 李丹
Original assignee: Shenzhen University General Hospital
Current assignee: Shenzhen University General Hospital
Priority date: 2020-05-11
Filing date: 2020-05-11
Publication date: 2021-04-20
Anticipated expiration: 2030-05-11

Abstract

The utility model discloses a device for establishing an animal model with extrusion syndrome, which comprises a base and a laboratory bench, wherein the laboratory bench is arranged above the base, the base is fixedly connected with the laboratory bench through two support plates which are symmetrically arranged, one side of the top of the laboratory bench is fixedly connected with two connecting blocks which are symmetrically arranged, one side of one connecting block is rotatably connected with a threaded rod, one end of the threaded rod penetrates through the other connecting block and extends outwards, the threaded rod is sleeved with two clamping plates, the threads in the two clamping plate threads are oppositely arranged, the top of the end of the laboratory bench far away from the connecting blocks is fixedly connected with a fixed frame, a screw rod is inserted on the fixed frame, the bottom of the screw rod is fixedly connected with a pressure plate, the device can effectively fix the animal when the animal extrusion injury model is manufactured through the arrangement of a clamping and fixing mechanism, avoid the quality of experiment that the animal removes the influence.

Description

Device for establishing extrusion syndrome animal model

Technical Field

The utility model relates to a relevant goods field of medical instrument specifically is a device of establishing extrusion syndrome animal model.

Background

Rhabdomyolysis can lead to acute kidney injury. Acute kidney injury (namely crush syndrome) caused by traumatic rhabdomyolysis is an important disease causing death of the wounded due to earthquake, debris flow, collapse and other natural disasters, and the death rate of the acute kidney injury is second to that of the wounded due to earthquake and is only second to direct trauma. Although the liquid therapy has an important therapeutic effect on acute kidney injury caused by traumatic rhabdomyolysis, severe complications such as multiple organ insufficiency, sepsis and the like are frequently complicated for patients with severe crush syndrome, and the liquid therapy is the most difficult disease to treat after earthquake disasters. Exploring the key pathogenic factors of traumatic rhabdomyolysis is important to analyze the generation and development mechanism of the rhabdomyolysis, optimize the treatment scheme and reduce the high mortality rate of the rhabdomyolysis.

But the device external structure of current establishment extrusion syndrome animal model is comparatively simple, can't be effectual when animal extrusion wound model preparation fix the animal, and the animal removes when the experiment and can lead to the experimental efficiency to reduce, has certain defectiveness.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a device of building extrusion syndrome animal model to it is comparatively simple to provide the device external structure who has the existing building extrusion syndrome animal model in solving above-mentioned background art, can't effectually fix the animal when animal extrusion injury model preparation, and the animal removes when the experiment and can lead to experimental efficiency to reduce the problem.

In order to achieve the above object, the utility model provides a following technical scheme: a device for establishing an animal model of extrusion syndrome comprises a base and a laboratory bench, wherein the laboratory bench is arranged above the base, the base is fixedly connected with the laboratory bench through two support plates which are symmetrically arranged, one side of the top of the laboratory bench is fixedly connected with two connecting blocks which are symmetrically arranged, one side of one connecting block is rotatably connected with a threaded rod, one end of the threaded rod penetrates through the other connecting block and extends outwards, two clamping plates are sleeved on the threaded rod in a threaded manner, threads in the two clamping plate threads are oppositely arranged, a fixing frame is fixedly connected with the top of one end of the laboratory bench, which is far away from the connecting blocks, a lead screw is inserted in the fixing frame in a threaded manner, a pressurizing plate is fixedly connected with the bottom end of the lead screw, a groove is arranged at the top of the laboratory bench, which corresponds to the position of the fixing frame, a pressure detection, the top of the bearing plate is fixedly connected with a display device, and the display device is electrically connected with the pressure detection device.

Preferably, the bottom of base fixedly connected with a plurality of moving mechanism, it is a plurality of moving mechanism is universal auto-lock wheel.

Preferably, two equal sliding insertion of connecting block is equipped with the gag lever post, the one end of gag lever post and the outer wall fixed connection of splint.

Preferably, fixedly connected with blotter on the inside wall of splint, the blotter material is the sea.

Preferably, a placing plate is fixedly connected between the two supporting plates, a slot is formed in the placing plate, and a collecting box is inserted into the slot.

Preferably, the top of the screw rod and one end of the threaded rod extending are fixedly connected with rotating blocks.

Compared with the prior art, the beneficial effects of the utility model are that:

1. the device for establishing the animal model of the crush syndrome is characterized in that an animal to be tested is placed on a test bench, through rotating the threaded rod of installing on the connecting block, the threaded rod will drive two splint removals when rotating, thereby two splint carry out the centre gripping fixed with the truck of animal in the relative movement that sets up of opposite screw socket, avoid the animal to move indiscriminately when the experiment, the user's accessible rotates the lead screw and rotates on the mount, thereby the lead screw promotes the increased pressure plate to push down gradually the downstream on the mount, the increased pressure plate extrudees the animal, the extrusion force detects through pressure measurement, pressure measurement sends pressure signal numerical value for display device demonstration afterwards, the utility model discloses a setting of centre gripping fixed establishment can carry out effectual fixed to the animal when animal extrusion wound model preparation, avoids the animal to remove the quality that influences the experiment.

Drawings

Fig. 1 is a schematic structural diagram of an apparatus for creating an animal model of crush syndrome according to the present invention;

fig. 2 is a schematic side view of a connecting block of the device for establishing an animal model of crush syndrome according to the present invention;

fig. 3 is a schematic view of a side view of the fixing frame of the device for establishing an animal model of crush syndrome of the present invention.

In the figure: 1-base, 2-experiment table, 3-support plate, 4-connecting block, 5-threaded rod, 6-clamping plate, 7-fixing frame, 8-screw rod, 9-pressurizing plate, 10-pressure detection device, 11-bearing plate, 12-display device, 13-moving mechanism, 14-buffer pad, 15-placing plate, 16-collecting box, 17-rotating block and 18-limiting rod.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.

Referring to fig. 1-3, the present invention provides an embodiment: a device for establishing an animal model of extrusion syndrome comprises a base 1 and an experiment table 2, wherein the experiment table 2 is arranged above the base 1, the base 1 is fixedly connected with the experiment table 2 through two support plates 3 which are symmetrically arranged, one side of the top of the experiment table 2 is fixedly connected with two connecting blocks 4 which are symmetrically arranged, one side of one connecting block 4 is rotatably connected with a threaded rod 5, one end of the threaded rod 5 penetrates through the other connecting block 4 and extends outwards, the threaded rod 5 is in threaded sleeve connection with two clamping plates 6, the threads in the threads of the two clamping plates 6 are oppositely arranged, the top of one end of the experiment table 2 far away from the connecting block 4 is fixedly connected with a fixing frame 7, a screw rod 8 is inserted in the fixing frame 7 through threads, the bottom end of the screw rod 8 is fixedly connected with a pressurizing plate 9, the top of the experiment table 2 corresponding to, a bearing plate 11 is fixedly connected on the outer wall of one end of the experiment table 2, a display device 12 is fixedly connected on the top of the bearing plate 11, the display device 12 is electrically connected with the pressure detection device 10, specifically speaking, an animal to be tested is placed on the experiment table 2, install threaded rod 5 on connecting block 4 through rotating, threaded rod 5 will drive two splint 6 and remove when rotating, thereby two splint 6 carry out the centre gripping fixed with the truck of animal in the relative movement that sets up of opposite screw socket, avoid the animal to move about when the experiment, the user accessible rotates lead screw 8 and rotates on mount 7, thereby lead screw 8 promotes increased pressure plate 9 and pushes down gradually the downstream on mount 7, increased pressure plate 9 extrudees the animal, the extrusion force detects through pressure detection device 10, pressure detection device 10 sends pressure signal numerical value afterwards and shows for display device 12.

Further, a plurality of moving mechanisms 13 are fixedly connected to the bottom of the base 1, and the moving mechanisms 13 are all universal self-locking wheels and are convenient to move.

Furthermore, all slide on two connecting blocks 4 and insert and be equipped with gag lever post 18, the one end of gag lever post 18 and the outer wall fixed connection of splint 6 increase the stability when splint 6 follows threaded rod 5 and removes.

Further, fixedly connected with blotter 14 on the inside wall of splint 6, the 14 materials of blotter are the sponge, increase the centre gripping buffering.

Further, fixedly connected with places board 15 between two backup pads 3, places and is equipped with the slot on board 15, and the slot interpolation is equipped with collects box 16, is convenient for collect the experimental apparatus.

Furthermore, the top of lead screw 8 and the one end that threaded rod 5 extends all fixedly connected with change piece 17, conveniently rotate.

The working principle is as follows: at first will treat the experimental animal and place on laboratory bench 2, install threaded rod 5 on connecting block 4 through rotating, threaded rod 5 will drive two splint 6 and remove when rotating, thereby two splint 6 carry out the centre gripping fixed with the truck of animal in the setting relative movement of opposite screw socket, avoid animal's indiscriminate when the experiment, user's accessible rotates lead screw 8 and rotates on mount 7, thereby lead screw 8 promotes increased pressure plate 9 and pushes down on mount 7 gradually the downstream, increased pressure plate 9 extrudees the animal, the extrusion force detects through pressure measurement device 10, pressure measurement device 10 sends pressure signal numerical value for display device 12 to show afterwards.

It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Claims

1. The utility model provides a device of building extrusion syndrome animal model, includes base (1) and laboratory bench (2), its characterized in that: the experiment table (2) is arranged above the base (1), two supporting plates (3) which are symmetrically arranged are fixedly connected between the base (1) and the experiment table (2), two connecting blocks (4) which are symmetrically arranged are fixedly connected to one side of the top of the experiment table (2), one side of one connecting block (4) is rotatably connected with a threaded rod (5), one end of the threaded rod (5) penetrates through the other connecting block (4) and extends outwards, two clamping plates (6) are sleeved on the threaded rod (5) in a threaded manner, threads in the clamping plates (6) are oppositely arranged, a fixing frame (7) is fixedly connected to the top of one end, far away from the connecting blocks (4), of the experiment table (2), a lead screw (8) is inserted into the threads on the fixing frame (7), and a pressurizing plate (9) is fixedly connected to the bottom end of the lead screw (8), the test bench (2) is equipped with the recess with the top that mount (7) position corresponds, be equipped with pressure measurement device (10) in the recess, fixedly connected with loading board (11) on the one end outer wall of test bench (2), the top fixedly connected with display device (12) of loading board (11), display device (12) and pressure measurement device (10) electric connection.

2. The device of claim 1, wherein the animal model of crush syndrome comprises: the bottom fixedly connected with of base (1) is a plurality of moving mechanism (13), and is a plurality of moving mechanism (13) are universal auto-lock wheel.

3. The device of claim 1, wherein the animal model of crush syndrome comprises: limiting rods (18) are slidably inserted into the two connecting blocks (4), and one ends of the limiting rods (18) are fixedly connected with the outer wall of the clamping plate (6).

4. The device of claim 1, wherein the animal model of crush syndrome comprises: fixedly connected with blotter (14) on the inside wall of splint (6), blotter (14) material is the sponge.

5. The device of claim 1, wherein the animal model of crush syndrome comprises: two fixedly connected with places board (15) between backup pad (3), place and be equipped with the slot on board (15), the slot interpolation is equipped with collection box (16).

6. The device of claim 1, wherein the animal model of crush syndrome comprises: and the top of the screw rod (8) and one end of the threaded rod (5) extending are fixedly connected with a rotating block (17).