CN212979249U - Novel hyperelastic bone material 3D printing apparatus - Google Patents
Novel hyperelastic bone material 3D printing apparatus Download PDFInfo
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- CN212979249U CN212979249U CN202020591075.2U CN202020591075U CN212979249U CN 212979249 U CN212979249 U CN 212979249U CN 202020591075 U CN202020591075 U CN 202020591075U CN 212979249 U CN212979249 U CN 212979249U
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Abstract
The utility model provides a novel super-elastic bone material 3D printing apparatus, includes chassis (1) and top surface welded door frame support (10), guide arm system frame (11) are installed to the front side of support (10), controller (2), its characterized in that are installed on the top of support (10): the bone clearing device is characterized in that a material disc (3) is arranged at the top end of the support (10), filamentous hyperelastic bone materials (30) are wound on a concave surface in the middle of the material disc (3), and a clearing seat plate (4) is arranged below the material disc (3). The utility model discloses a product that novel hyperelastic bone material 3D printing apparatus made has good biocompatibility: the material of the artificial bone is nontoxic and non-teratogenic, is beneficial to the adhesion and proliferation of seed cells, and degradation products have no toxic or side effect and do not cause inflammatory reaction and the like.
Description
Technical Field
The utility model relates to an orthopedics 3D prints technical field, specifically is a novel hyperelastic bone material 3D printing apparatus.
Background
The traditional chemical and physical method is adopted to manufacture the material bracket originally, the porosity prepared by the method can not be controlled, and the physicochemical property and the biocompatibility can not meet the clinical requirements. The porosity of the hyperelastic bone material can be controlled by a 3D printing technology, so that the printed hyperelastic bone material tissue has accurate porosity to meet clinical requirements. However, some low-mix 3D printing devices do not have a housing, and their material discs are also exposed, which can accumulate dust and affect the porosity of the printed product.
Contributes to bone repair in patients with bone defects. For a long time, the repair of bone defects caused by wounds or tumors is not effectively solved, often leads to the disability or deformity of patients, seriously influences the life quality and physical and mental health of the patients, and is a common clinical treatment problem faced by the prior orthopedics department. The adoption of an effective bone grafting method is the key point for solving the problem. The hyperelastic bone material tissue engineering artificial bone is printed by 3D to treat bone defects, has mechanical properties similar to those of natural bone, can provide certain strength, and can effectively promote the formation of new bone. The artificial bone constructed by the method is expected to become an effective biological material for bone defect repair, the superelastic bone material tissue engineering artificial bone constructed based on the 3D printing technology is expected to become an effective treatment method for patients with bone defects, and the technology is expected to solve the problem of bone defect repair, so that the life quality of the patients is improved, and the huge economic burden of the patients and the families is effectively reduced.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a novel hyperelastic bone material 3D printing apparatus to solve the problem that proposes among the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme:
A3D-printed superelastic artificial bone, comprising: the device comprises transverse extrusion structures 5, longitudinal extrusion structures 6 and interlayer connection points 7, wherein the transverse extrusion structures 5 are connected into unit layer stacks through the longitudinal extrusion structures 6, and the unit layer stacks are connected into a whole through the interlayer connection points 7.
The utility model provides a novel super-elastic bone material 3D printing apparatus, includes chassis 1 and its top surface welded door frame support 10, guide arm system frame 11 is installed to the front side of support 10, controller 2, its characterized in that are installed to the top of support 10: the top of support 10 is provided with material dish 3, the winding has on the middle concave surface of material dish 3 is threadlike hyperelastic bone material 30, the below of material dish 3 is provided with clearance bedplate 4, clearance bedplate 4 is L type structure and a side center is equipped with ring platform 40, the inside inseparable joint of ring platform 40 has bearing 41, the inside grafting of inner circle of bearing 41 has revolved post 42, a terminal surface symmetry of revolving post 42 is equipped with lug 420, lug 420 front end swing joint has clearance cover 43, high density sponge 430 has been cup jointed to the inside of clearance cover 43, hyperelastic bone material 30 with the inside grafting of high density sponge 430.
The print head 110 is mounted on the X-axis of the guide rod system frame 11, and the print head 110 penetrates the superelastic bone material 30.
A porosity calculation system module 20 is installed on the inner main board of the controller 2, and a porosity adjusting button 21 is installed on the outer side surface of the controller 2.
Fixed lagging 31 has been cup jointed to the one end of material dish 3, fixed lagging 31 with support 10 passes through bolt fixed connection, the other end of material dish 3 is provided with spacing spiral cover 32.
The cleaning seat plate 4 is clamped at the edge of the support 10 and fixedly connected with the support through bolts.
The side surface of the front end of the convex block 420 is provided with a through hole 421, the center of one side of the cleaning sleeve 43 is provided with a lantern ring 431, and the lantern ring 431 is arranged between the two convex blocks 420 and is internally inserted with a pin 44.
Compared with the prior art, the beneficial effects of the utility model are that:
the utility model has the social benefit of contributing to the bone repair of patients with bone defect. For a long time, the repair of bone defects caused by wounds or tumors is not effectively solved, often leads to the disability or deformity of patients, seriously influences the life quality and physical and mental health of the patients, and is a common clinical treatment problem faced by the prior orthopedics department. The adoption of an effective bone grafting method is the key point for solving the problem. The hyperelastic bone material tissue engineering artificial bone is printed by 3D to treat bone defects, has mechanical properties similar to those of natural bone, can provide certain strength, and can effectively promote the formation of new bone. The utility model discloses the artificial bone of structure is expected to become the prosthetic effective biomaterial of bone defect, constructs the artificial bone of super-elastic bone material tissue engineering based on 3D printing technique and is expected to become the effective treatment method of the patient of bone defect, and this technique hopefully solves the prosthetic difficult problem of bone defect to improve patient's quality of life, effectively alleviate the huge economic burden of patient and family members.
The utility model discloses the characteristics of super-elastic bone material tissue engineering artificial bone are found to the 3D printing technique of preparation:
the biological compatibility is good: the material of the artificial bone is nontoxic and non-teratogenic, is beneficial to the adhesion and proliferation of seed cells, and degradation products have no toxic or side effect and do not cause inflammatory reaction and the like.
② has good biodegradability: the artificial bone can be degraded after the supporting function is finished, and the degradation rate is adapted to the growth rate of tissue cells.
③ has three-dimensional porous structure: the super-elastic bone material tissue engineering artificial bone constructed by the 3D printing technology has proper pore diameter, high porosity, higher internal specific surface area and interpenetration among pore canals, is beneficial to cell adhesion growth, blood vessel and nerve growth, and is also beneficial to nutrient infiltration and metabolite discharge.
Fourthly, the material has good plasticity: the super-elastic bone material tissue engineering artificial bone constructed by the 3D printing technology can be prefabricated into a specific shape according to the bone defect condition.
The material has certain mechanical strength: the artificial bone can provide support for the new tissue and maintain for a certain time until the new tissue has the own biomechanical characteristics.
Sixthly, the biocompatibility is good: the artificial bone is beneficial to cell adhesion and proliferation, and more importantly, can activate cell specific gene expression and maintain normal phenotype expression of cells.
The utility model discloses preparation technical novelty: the hyperelastic bone material tissue engineering artificial bone is prepared by adopting a fusion blending and 3D printing technology, and the technology can directly form the required artificial bone at one time according to individual conditions by digital information processing of medical images and tissue structures. The artificial bone can provide more material choices, can realize the space multi-dimension and surface biological pore processing of the artificial bone, realizes light weight while solving the defects of the prior large solid, is closer to the biological characteristics, obtains better compatibility, further reduces the possibility of occurrence of complications, improves the postoperative life quality of patients, and has great application value. Compared with the traditional preparation method, the preparation technology of the artificial bone does not need organic solvents, can eliminate the toxicity and teratogenicity of liver and kidney induced by organic solvents such as chloroform and the like to the maximum extent, and overcomes the defects of solvent residue, difficult control of hole shape, complex preparation process, poor cell compatibility, difficult cell growth and adhesion and the like of the artificial bone prepared by the traditional method. And the corresponding bone tissue engineering scaffold can be manufactured according to the shape and the size of the bone defect, which is incomparable with other traditional manufacturing methods.
The innovation of the artificial bone is as follows: the utility model discloses an artificial bone adopts nanometer hydroxyapatite/polycaprolactone to prepare bone tissue engineering support for raw and other materials, and nanometer hydroxyapatite is similar with the composition of natural bone, has the promotion effect to the secretion of bone growth enzyme and albumen, and polycaprolactone's mechanical properties is better. The prepared bone tissue engineering scaffold can integrate the advantages of two materials, and has better mechanical property and cell compatibility compared with the traditional scaffold.
According to the novel hyperelastic bone material 3D printing equipment and the process, the porosity of the printed hyperelastic bone material tissue is accurately controlled by controlling the controller provided with the porosity calculation system module and adjusting by using the porosity adjusting button; meanwhile, the cleaning seat plate is arranged below the material disc, the filamentous superelastic bone material penetrates through the cleaning sleeve, the superelastic bone material is continuously extruded out of the printing head along with printing of equipment, and therefore a printed product is free of impurities due to wiping of high-density sponge in the cleaning sleeve, and control of finished product porosity is facilitated.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention;
fig. 2 is a schematic structural diagram of the controller of the present invention;
fig. 3 is an exploded view of the material tray of the present invention;
FIG. 4 is a schematic view of the overall structure of the cleaning seat plate of the present invention;
fig. 5 is an exploded view of the cleaning seat plate of the present invention.
Fig. 6 is one of the schematic diagrams of the product of the present invention.
Fig. 7 is a second schematic diagram of the product of the present invention.
The meaning of the individual reference symbols in the figures is:
1. a chassis; 10. a support; 11. a guide rod system frame; 110. a print head; 2. a controller; 20. a porosity calculation system module; 21. a porosity adjustment button; 3. a material tray; 30. a super-elastic bone material; 31. fixing the sleeve plate; 32. limiting and screwing a cover; 4. cleaning the seat board; 40. a circular ring table; 41. a bearing; 42. rotating the column; 420. a bump; 421. a through hole; 43. Cleaning the sleeve; 430. a high density sponge; 431. a collar; 44. a pin; 5. a transverse extrusion structure; 6. a longitudinal extrusion structure; 7. and connecting points between layers.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it should be understood that the terms "center", "center line", "longitudinal", "lateral", "length", "width", "thickness", "depth", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for convenience of description and simplicity of description, and are not intended to indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be taken as limiting the invention, in the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
Referring to fig. 1-7, the present invention provides a technical solution:
the utility model provides a novel hyperelastic bone material 3D printing apparatus, in order to avoid having the impurity of particulate matter such as dust in the printed matter, the utility model discloses the people has set up clearance bedplate 4. The printer comprises an underframe 1 and a door frame type support 10 welded on the top surface of the underframe, wherein a guide rod system frame 11 is arranged on the front side of the support 10 and is divided into X-axis guide rods and Y-axis guide rods, so that a printing head 110 moves up and down, left and right. The top end of the support 10 is provided with a controller 2 for controlling the operation of the apparatus and adjusting the printing parameters. The top end of the bracket 10 is provided with a material disc 3, and the concave surface in the middle of the material disc 3 is wound with filamentous super-elastic bone material 30. The below of material dish 3 is provided with clearance bedplate 4, and clearance bedplate 4 is L type structure and a side center is equipped with ring platform 40, and the inside inseparable joint of ring platform 40 has bearing 41, and bearing 41's inner circle is inside to be pegged graft there is rotary column 42 for rotary column 42 can control free rotation. One end face of the rotary column 42 is symmetrically provided with a convex block 420, and the front end of the convex block 420 is movably connected with a cleaning sleeve 43, so that the cleaning sleeve 42 can freely swing back and forth. The cleaning cover 43 is sleeved with a high-density sponge 430 and bonded firmly. The superelastic bone material 30 is inserted into the high density sponge 430 to facilitate wiping away particulate matter from the surface.
In this embodiment, the cleaning seat plate 4 is made of PP material and has an integrally formed structure, which is light in weight, good in toughness and rigid in strength, so that it is durable. Wherein the cleaning sleeve 43 can be used for standby, the pin 44 is ejected, the cleaning sleeve 43 can be replaced, and the high-density sponge 430 in the cleaning sleeve is cleaned. Wherein the composition of the superelastic bone material 30 is similar to the composition of bone, is useful in medical applications for making bone substitutes.
Further, a print head 110 is installed on the X-axis of the guide bar system frame 11, the super-elastic bone material 30 is penetrated inside the print head 110, and the print head 110 can melt the super-elastic bone material 30 inside thereof to be overlapped on a worktable installed on the bottom chassis 1 in a molten state, thereby performing 3D molding.
Specifically, a porosity calculation system module 20 is installed on the internal main board of the controller 2, and is used for calculating the porosity of the printed product and ensuring the strength and toughness of the finished product. The outer side of the controller 2 is provided with a porosity adjusting button 21 for adjusting the relevant parameters of the porosity.
Specifically, a fixed sleeve plate 31 is sleeved at one end of the material disc 3, the fixed sleeve plate 31 is fixedly connected with the support 10 through a bolt, a limiting screw cap 32 is arranged at the other end of the material disc 3, and the limiting screw cap 32 is in threaded connection with the fixed sleeve plate 31, so that the material disc 3 freely rotates on a central cylinder of the fixed sleeve plate 31, and the hyperelastic bone material 30 is stably pulled out.
In addition, the cleaning seat plate 4 is clamped at the edge of the bracket 10 and fixedly connected with the edge through bolts, so that the cleaning seat plate is stable.
It needs to be supplemented that the side surface of the front end of the convex block 420 is provided with a through hole 421, the center of one side of the cleaning sleeve 43 is provided with a lantern ring 431, the lantern ring 431 is arranged between the two convex blocks 420, and the inside of the lantern ring 431 is inserted with the pin 44, wherein the inner diameter of the lantern ring 431 is larger than the outer diameter of the pin 44, so that the cleaning sleeve 43 can swing back and forth between the two convex blocks 420.
Before printing, the novel hyperelastic bone material 3D printing equipment of the utility model passes hyperelastic bone material 30 through high-density sponge 430 in the cleaning sleeve 43, then is inserted into the printing head 110, works by connecting the power supply of the controller 2, and then sets the porosity parameter by adjusting the porosity adjusting button 21; as the device prints, the superelastic bone material 30 is continuously extruded out of the print head 110 and is wiped by the high-density sponge 430 in the cleaning sleeve 43, so that the printed product is free of impurities, and the porosity of the printed product is controlled.
A novel 3D printing process for super-elastic bone materials comprises the following steps:
step 1, drying the nano hydroxyapatite powder and the polycaprolactone particles in a drying oven at 40 ℃ for 24 hours for later use;
and 2, preparing the nano hydroxyapatite/polycaprolactone blend by adopting a melt blending method. Firstly banburying for 5min at the rotating speed of 10r/min, weighing nano hydroxyapatite powder and polycaprolactone particles according to the proportion of 1:3, mechanically stirring and uniformly mixing, placing in a torque rheometer, blending for 8min at the rotating speed of 100r/min and the temperature of 160 ℃, and stopping when the torque is horizontal to obtain the nano hydroxyapatite/polycaprolactone blend;
step 3, putting the blend particles into a special extruder for the 3D printing wire rod to be processed into filaments, wherein the extrusion temperature is 80 ℃, and obtaining the 3D printing wire rod with the diameter of 1.75 +/-0.2 mm;
and 5, printing the bone tissue engineering scaffold with the computer-aided design by the obtained printing wire through a 3D printer, wherein the printing parameters of the 3D printer are set as follows: 195 deg.C, 0.4mm inner diameter of the nozzle, 0.4MPa printing pressure and 10mm/s printing speed. The nano hydroxyapatite/polycaprolactone bone tissue engineering scaffold with good mechanical property and biocompatibility is prepared.
A3D-printed superelastic artificial bone, comprising: the device comprises transverse extrusion structures 5, longitudinal extrusion structures 6 and interlayer connection points 7, wherein the transverse extrusion structures 5 are connected into unit layer stacks through the longitudinal extrusion structures 6, and the unit layer stacks are connected into a whole through the interlayer connection points 7.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It should be understood by those skilled in the art that the present invention is not limited by the above embodiments, and the description in the above embodiments and the description is only preferred examples of the present invention, and is not intended to limit the present invention, and that the present invention can have various changes and modifications without departing from the spirit and scope of the present invention, and these changes and modifications all fall into the scope of the claimed invention. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (6)
1. The utility model provides a novel super-elastic bone material 3D printing apparatus, includes chassis (1) and top surface welded door frame support (10), guide arm system frame (11) are installed to the front side of support (10), controller (2), its characterized in that are installed on the top of support (10): the top of support (10) is provided with material dish (3), the winding has on the middle concave surface of material dish (3) and is filiform hyperelastic bone material (30), the below of material dish (3) is provided with clearance bedplate (4), clearance bedplate (4) are L type structure and a side center is equipped with ring platform (40), the inside inseparable joint of ring platform (40) has bearing (41), the inside grafting of inner circle of bearing (41) has revolved post (42), a terminal surface symmetry of revolving post (42) is equipped with lug (420), lug (420) front end swing joint has clearance cover (43), high density sponge (430) have been cup jointed to the inside of clearance cover (43), hyperelastic bone material (30) with the inside grafting of high density sponge (430).
2. The novel 3D printing device for superelastic bone material according to claim 1, wherein: a printing head (110) is installed on the X axis of the guide rod system frame (11), and the printing head (110) penetrates through the super-elastic bone material (30).
3. The novel 3D printing device for superelastic bone material according to claim 1, wherein: the porosity calculation system is characterized in that a porosity calculation system module (20) is installed on an inner main board of the controller (2), and a porosity adjusting button (21) is installed on the outer side face of the controller (2).
4. The novel 3D printing device for superelastic bone material according to claim 1, wherein: fixed lagging (31) has been cup jointed to the one end of material dish (3), fixed lagging (31) with support (10) pass through bolt fixed connection, the other end of material dish (3) is provided with spacing spiral cover (32).
5. The novel 3D printing device for superelastic bone material according to claim 1, wherein: the cleaning seat plate (4) is clamped at the edge of the support (10) and fixedly connected with the support through bolts.
6. The novel 3D printing device for superelastic bone material according to claim 1, wherein: the side face of the front end of each bump (420) is provided with a through hole (421), the center of one side of each cleaning sleeve (43) is provided with a lantern ring (431), and the lantern rings (431) are arranged between the two bumps (420) and are internally inserted with pins (44).
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| Application Number | Priority Date | Filing Date | Title |
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| CN202020591075.2U CN212979249U (en) | 2020-04-20 | 2020-04-20 | Novel hyperelastic bone material 3D printing apparatus |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202020591075.2U CN212979249U (en) | 2020-04-20 | 2020-04-20 | Novel hyperelastic bone material 3D printing apparatus |
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| CN212979249U true CN212979249U (en) | 2021-04-16 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117183326A (en) * | 2023-09-25 | 2023-12-08 | 江苏海洋大学 | Novel super-elastic bone material 3D printing equipment |
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2020
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117183326A (en) * | 2023-09-25 | 2023-12-08 | 江苏海洋大学 | Novel super-elastic bone material 3D printing equipment |
| CN117183326B (en) * | 2023-09-25 | 2024-03-01 | 江苏海洋大学 | Super-elastic bone material 3D printing equipment |
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