CN212942933U - Oratinib synthesizer - Google Patents

Oratinib synthesizer Download PDF

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Publication number
CN212942933U
CN212942933U CN202021680531.7U CN202021680531U CN212942933U CN 212942933 U CN212942933 U CN 212942933U CN 202021680531 U CN202021680531 U CN 202021680531U CN 212942933 U CN212942933 U CN 212942933U
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fixedly connected
stirring
rod
annular
side wall
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赵跃
陈晨
陈力
万新锋
王杰明
周深
程壮壮
程志勇
杨延召
张鹏伟
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Anqing Duohui Biotechnology Co ltd
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Anqing Duohui Biotechnology Co ltd
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Abstract

The utility model discloses an Olatinib synthesizer, which comprises stirring components, wherein each stirring component comprises a stirring rod, the bottom of each stirring rod is fixedly connected with a base, each base is concentrically provided with an annular rod, and a plurality of annularly distributed stirring plates are fixedly connected between the inner side wall of each annular rod and the corresponding base; the lower end of the side wall of the stirring rod is rotatably connected with a bearing, the inner ring of the bearing is fixedly connected to the stirring rod, the outer ring of the bearing is fixedly connected with two vertical rods which are symmetrically arranged left and right, and a top plate body is fixedly connected between the tops of the vertical rods; the stirring rod is rotationally connected with the top plate body; the outer side wall of the annular rod is fixedly connected with a plurality of sampling tubes distributed in an annular array. The above-described device component design enables multiple sample solutions to be sampled simultaneously. Not only improved the homogeneity of sample, and above-mentioned device part design convenient operation, can nimble rotatory stirring, effectively improved sampling efficiency.

Description

Oratinib synthesizer
Technical Field
The utility model relates to an oratinib synthesizer field especially relates to an oratinib synthesizer.
Background
The olatinib has the following chemical formula structure:
Figure BDA0002631016490000011
in the industrial processing and synthesis process of the olatinib, the material in the kettle is often required to be sampled, and the crystallization condition of the material is judged by sampling when recrystallization is carried out in the synthesis step.
The sampling device has the advantages that reaction stirring needs to be stopped in the sampling process, sampling points cannot be properly stirred in the sampling process of the sampling device, so that the sampling is not uniform enough, and meanwhile, the sampling device disclosed by the prior art can only sample a single sample at one time, and the sampling amount is very small.
SUMMERY OF THE UTILITY MODEL
The utility model aims to solve the technical problem that an oratinib synthesizer is provided.
The utility model discloses a solve above-mentioned technical problem through following technical scheme:
an Olatinib synthesis device comprises stirring assemblies, wherein each stirring assembly comprises a stirring rod, the bottom of each stirring rod is fixedly connected with a base, the bases are concentrically provided with annular rods, and a plurality of annularly distributed stirring plates are fixedly connected between the inner side wall of each annular rod and each base;
the lower end of the side wall of the stirring rod is rotatably connected with a bearing, the inner ring of the bearing is fixedly connected to the stirring rod, the outer ring of the bearing is fixedly connected with two vertical rods which are symmetrically arranged left and right, and a top plate body is fixedly connected between the tops of the vertical rods;
the stirring rod is rotationally connected with the top plate body;
the outer side wall of the annular rod is fixedly connected with a plurality of sampling tubes distributed in an annular array.
Preferably, the top fixed connection of puddler has the rotatory disk body, the eccentric position fixed connection of rotatory disk body has the hand pole.
Preferably, the vertical rod has an L-shaped longitudinal cross-sectional shape;
the bottom of the vertical rod is provided with a connecting end, and the bottom of the vertical rod is fixedly connected to the bearing.
Preferably, the sampling tube is fixedly connected with the outer side wall of the annular rod through a connecting column.
Preferably, the longitudinal section of the stirring plate is rectangular, and two sides of the stirring plate are welded between the base and the inner side wall of the annular rod;
the top of the stirring plate is positioned above the annular rod;
the bottom of the stirring plate is positioned below the annular rod.
Preferably, the longitudinal cross-sectional shape of the sampling tube is conical.
Preferably, a handle bar is fixedly connected to the top of the top plate body.
Preferably, the handle rod comprises a cross rod part, the left end and the right end of the cross rod part are provided with connecting rod parts, and the connecting rod parts are fixedly connected to the top plate body.
Compared with the prior art, the utility model has the following advantages:
the utility model discloses an Olatinib synthesizer, which comprises stirring components, wherein each stirring component comprises a stirring rod, the bottom of each stirring rod is fixedly connected with a base, each base is concentrically provided with an annular rod, and a plurality of annularly distributed stirring plates are fixedly connected between the inner side wall of each annular rod and the corresponding base; the lower end of the side wall of the stirring rod is rotatably connected with a bearing, the inner ring of the bearing is fixedly connected to the stirring rod, the outer ring of the bearing is fixedly connected with two vertical rods which are symmetrically arranged left and right, and a top plate body is fixedly connected between the tops of the vertical rods; the stirring rod is rotationally connected with the top plate body; the outer side wall of the annular rod is fixedly connected with a plurality of sampling tubes distributed in an annular array.
The above-described device component design enables multiple sample solutions to be sampled simultaneously. Not only improved the homogeneity of sample, and above-mentioned device part design convenient operation, can nimble rotatory stirring, effectively improved sampling efficiency.
Drawings
Fig. 1 is a schematic overall structure diagram of an embodiment of the present invention;
FIG. 2 is a schematic view of the connection relationship between the ring-shaped rod and the stirring plate in the embodiment of the present invention;
fig. 3 is a front view of the embodiment of the present invention shown in fig. 1;
fig. 4 is a top view of the embodiment of the present invention in fig. 1;
fig. 5 is a schematic structural diagram of another view angle in fig. 1 according to the embodiment of the present invention.
Detailed Description
The embodiments of the present invention will be described in detail below, and the present embodiment is implemented on the premise of the technical solution of the present invention, and a detailed implementation manner and a specific operation process are given, but the scope of the present invention is not limited to the following embodiments.
As shown in fig. 1-5, an olatinib synthesis device comprises stirring assemblies 1, wherein each stirring assembly 1 comprises a stirring rod 14, a base 15 is fixedly connected to the bottom of each stirring rod 14, annular rods 11 are concentrically arranged on the bases 15, and a plurality of annularly distributed stirring plates 12 are fixedly connected between the inner side wall of each annular rod 11 and the base 15.
The lateral wall lower extreme of puddler 14 rotates and is connected with bearing 13, specifically is antifriction bearing 13, and the inner circle fixed connection of bearing 13 is on puddler 14, the vertical rod that two left and right symmetries of outer lane fixedly connected with of bearing 13 set up (the longitudinal section shape of vertical rod is L shape), fixedly connected with handle subassembly 3 between the top of vertical rod has handle subassembly 3 to include ejector plate body 31, and simultaneously, the bottom of vertical rod has the link, the bottom fixed connection of vertical rod is on bearing 13.
The paddle 14 is rotatably connected to the top plate 31, specifically, a through hole is formed in the center of the top plate 31, the bearing 13 is fitted to the through hole, and the paddle 14 is rotatably connected to the bearing 13.
The outer side wall of the annular rod 11 is fixedly connected with the sampling tubes 2 distributed in a plurality of annular arrays, and specifically, the sampling tubes 2 are fixedly connected with the outer side wall of the annular rod 11 through connecting columns 21. The longitudinal cross-sectional shape of the sampling tube 2 is conical.
The top of the stirring rod 14 is fixedly connected with a rotating disc 141, and the eccentric part of the rotating disc 141 is fixedly connected with a hand lever 1411.
The longitudinal section of the stirring plate 12 is rectangular, and two sides of the stirring plate 12 are welded between the base 15 and the inner side wall of the annular rod 11; the top of the stirring plate 12 is positioned above the annular rod 11; the bottom of the agitating plate 12 is located below the ring-shaped bar 11.
Meanwhile, in order to facilitate the holding of the whole device, a handle bar 32 is fixedly connected to the top of the top plate body 31. The handle lever 32 includes a cross-bar portion having link portions at left and right ends thereof, the link portions being fixedly connected to the top plate body 31.
In the sample process, handle pole 32 is held to operating personnel hand, stretches into the material cauldron with puddler 14 this moment in, operating personnel rotates the hand pole 1411 at rotatory disk body 141 top, and at this moment, hand pole 1411 drive rotatory disk body 141, and it is rotatory that rotatory disk body 141 drive puddler 14 carries annular pole 11, and annular pole 11 carries stirring board 12 rotation, and this in-process, stirring board 12 stirs material solution.
The sample solution enters the sampling tube 2, and the solution stirring at the sampling position is realized flexibly in the sampling process by the mode, and meanwhile, the design of the parts of the device realizes the simultaneous sampling of a plurality of sample solutions. Not only improved the homogeneity of sample, and above-mentioned device part design convenient operation, can nimble rotatory stirring, effectively improved sampling efficiency.
The above description is only exemplary of the present invention and should not be taken as limiting the scope of the present invention, as any modifications, equivalents, improvements and the like made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.

Claims (8)

1. The device for synthesizing the Olatinib is characterized by comprising stirring components, wherein each stirring component comprises a stirring rod, the bottom of each stirring rod is fixedly connected with a base, the bases are concentrically provided with annular rods, and a plurality of annularly distributed stirring plates are fixedly connected between the inner side wall of each annular rod and each base;
the lower end of the side wall of the stirring rod is rotatably connected with a bearing, the inner ring of the bearing is fixedly connected to the stirring rod, the outer ring of the bearing is fixedly connected with two vertical rods which are symmetrically arranged left and right, and a top plate body is fixedly connected between the tops of the vertical rods;
the stirring rod is rotationally connected with the top plate body;
the outer side wall of the annular rod is fixedly connected with a plurality of sampling tubes distributed in an annular array.
2. The device for synthesizing oratinib according to claim 1, wherein a rotary disk body is fixedly connected to the top of the stirring rod, and a hand-operated rod is fixedly connected to the eccentric part of the rotary disk body.
3. The olaratinib synthesis apparatus according to claim 2, wherein the vertical rod is L-shaped in longitudinal cross-sectional shape;
the bottom of the vertical rod is provided with a connecting end, and the bottom of the vertical rod is fixedly connected to the bearing.
4. The device for synthesizing olatinib according to claim 3, wherein the sampling tube is fixedly connected with the outer side wall of the annular rod through a connecting column.
5. The device for synthesizing oratinib according to claim 4, wherein the longitudinal cross-sectional shape of the stirring plate is rectangular, and two sides of the stirring plate are welded between the base and the inner side wall of the annular rod;
the top of the stirring plate is positioned above the annular rod;
the bottom of the stirring plate is positioned below the annular rod.
6. The device of claim 5, wherein the longitudinal cross-sectional shape of the sampling tube is conical.
7. An olartinib synthesis device according to claim 6, characterized in that a handle bar is fixedly connected to the top of the top plate body.
8. The olaratinib synthesis device according to claim 7, wherein the handle bar includes a crossbar portion, and both left and right ends of the crossbar portion have link portions fixedly connected to the top plate body.
CN202021680531.7U 2020-08-13 2020-08-13 Oratinib synthesizer Active CN212942933U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202021680531.7U CN212942933U (en) 2020-08-13 2020-08-13 Oratinib synthesizer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202021680531.7U CN212942933U (en) 2020-08-13 2020-08-13 Oratinib synthesizer

Publications (1)

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CN212942933U true CN212942933U (en) 2021-04-13

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