CN212902158U - A low temperature freeze-drying equipment for pharmaceutic preparation - Google Patents

Abstract

The utility model discloses a low temperature freeze-drying equipment for pharmaceutic preparation, the power distribution box comprises a box body, the inside refrigeration chamber that opens of back lateral wall of box, and the internally mounted in refrigeration chamber has refrigeration plant, the place ahead of box articulates there is the chamber door, the box has a plurality of layer boards through a plurality of bearing mechanism activity joints that its inside was installed, and it has a plurality of standing grooves that are used for placing the medicine bottle to open on the layer board, the inside upper end fixedly connected with of box is used for guiding the guide plate of gaseous flow direction, and the inside of lateral wall is opened on the box has the transfer chamber, the transfer chamber respectively with the inside and the aspiration pump interconnect of box, the medicine bottle of placing that this device can be stable, and can reduce the influence that produces the medicine when bleeding.

Description

A low temperature freeze-drying equipment for pharmaceutic preparation

Technical Field

The utility model relates to a medicine preparation technical field specifically is a low temperature freeze-drying equipment for pharmaceutic preparation.

Background

Low temperature freeze-drying is a drying technology that utilizes sublimed principle to make the material dehydration, because vacuum freeze-drying technique is at low temperature, go on under the low oxygen environment, most biological reaction stagnation, and the processing procedure does not have liquid water to exist, moisture is with the direct sublimation of solid state, make original structure of material and shape obtain maximum protection, so the drying of pharmaceutical preparation is often applied to now, current low temperature freeze-drying equipment directly bleeds to equipment inside when making vacuum environment, cause the influence to the medicine easily, and current equipment generally is directly to put the medicine bottle on the layer board, cause the slope of medicine bottle askew easily, for solving above-mentioned problem the utility model provides a low temperature freeze-drying equipment for pharmaceutical preparation.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a low temperature freeze-drying equipment for pharmaceutic preparation to solve the problem that proposes among the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a low temperature freeze-drying equipment for pharmaceutic preparation, includes the box, the inside division of the back lateral wall of box has the refrigeration chamber, and the internally mounted in refrigeration chamber has refrigeration plant, the place ahead of box articulates there is the chamber door, the box has a plurality of layer boards through a plurality of bearing mechanism activity joints that its internally mounted has, and it has a plurality of standing grooves that are used for placing the medicine bottle to open on the layer board, the inside upper end fixedly connected with of box is used for guiding the guide plate of gaseous flow direction, and the inside of lateral wall is opened on the box has the transfer chamber, the transfer chamber respectively with the inside and the aspiration pump interconnect of box.

Preferably, the bearing mechanism comprises two sliding seats which are symmetrical to each other, each sliding seat comprises a first outer frame and a second outer frame, the first outer frames and the second outer frames are respectively connected with T-shaped rods through pulleys which are arranged inside, the first outer frames are arranged on the inner side wall of the box body, the second outer frames are fixedly connected with the T-shaped rods inside the first outer frames, bearing plates are fixedly connected with the outer sides of the T-shaped rods inside the second outer frames, and the bearing plates are movably clamped with the bearing plates.

Preferably, the bearing plate is provided with a plurality of square grooves, and a plurality of square rods matched with the square grooves are fixedly connected to two side surfaces of the supporting plate.

Preferably, every top of bearing the weight of the mechanism all is equipped with the base, the inside wall fixed connection of base and box, the below of base is equipped with the liftable clamp frame that is used for the centre gripping bottle lid, and the clamp frame is controlled by the adjusting bolt that the meshing is connected on the base.

Preferably, the equal sliding connection in four corners of base has the slide bar, be connected with the spring between the upper end of slide bar and the base, the lower extreme fixedly connected with connection frame of slide bar, the inserted bar of the both sides fixedly connected with and the connection frame looks adaptation of clamp frame, fixedly connected with is protruding on the inserted bar, open the arc groove that has with protruding looks adaptation on the inside wall of connection frame.

Preferably, the clamping frame is provided with a plurality of clamping grooves for placing bottle caps, one side of each clamping groove is provided with an empty groove in the clamping frame, the plurality of sliding plates are connected with each other through connecting rods, the front end faces of the clamping frames are meshed with clamping bolts, and the inner ends of the clamping bolts are rotatably connected with the corresponding sliding plates.

Preferably, the outer end of the lower side surface of the supporting plate is fixedly connected with a pulling plate, and four corners of the lower side surface of the supporting plate are fixedly connected with supporting legs.

Compared with the prior art, the beneficial effects of the utility model are that: the utility model discloses a setting of standing groove has realized that the medicine bottle that can directly hold the medicine when using is placed in the inside of standing groove to can make the medicine bottle remain stable and can not empty, this device has set up the guide plate in the below of extraction opening in addition, and the air current that can be fine reduction production when bleeding produces the influence to the medicine, and the medicine bottle is placed to what this device can be stable, can reduce the influence that produces the medicine in addition when bleeding.

Drawings

Fig. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a sectional view of the box body of the present invention;

FIG. 3 is a schematic view of the connection between the base and the box body according to the present invention;

FIG. 4 is an exploded view of the insertion rod and the connection frame of the present invention;

FIG. 5 is a schematic view of the connection between the insertion rod and the protrusion of the present invention;

fig. 6 is an exploded view of the slide carriage of the present invention;

FIG. 7 is a schematic view of the connection between the second frame and the T-bar of the present invention;

fig. 8 is a cross-sectional view of the first outer frame of the present invention;

FIG. 9 is a schematic structural view of the T-bar of the present invention;

FIG. 10 is an exploded view of the slide plate and the empty groove of the present invention;

FIG. 11 is an exploded view of the clamping bolt and the slide plate of the present invention;

fig. 12 is a schematic view i showing an opened state of the door of the present invention;

fig. 13 is a schematic view ii illustrating an opened state of the door of the present invention.

In the figure: 1. the box, 2, chamber door, 3, refrigeration chamber, 4, layer board, 5, standing groove, 6, guide plate, 7, transfer chamber, 8, aspiration pump, 9, slide, 901, first frame, 902, second frame, 903, pulley, 904, T shape pole, 905, loading board, 906, square groove, 907, square bar, 10, base, 11, clamping frame, 12, adjusting bolt, 13, slide bar, 14, spring, 15, connection frame, 16, inserted bar, 17, arch, 18, arc groove, 19, clamping groove, 20, dead slot, 21, slide, 22, connecting rod, 23, clamping bolt, 24, arm-tie, 25, landing leg.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Please refer to fig. 1-13;

the first embodiment is as follows:

the utility model provides a technical scheme: a low-temperature freeze-drying device for pharmaceutical preparations comprises a box body 1, wherein a refrigeration cavity 3 is formed in the back side wall of the box body 1, refrigeration equipment is arranged in the refrigeration cavity 3, the refrigeration cavity 3 is communicated with the interior of the box body 1 through a through groove formed in the side wall of the refrigeration cavity 3, cold air generated by the refrigeration equipment can enter the interior of the box body 1 through the through groove, so that the temperature in the box body 1 can be reduced, a box door 2 is hinged to the front side of the box body 1, bosses are fixedly connected to the inner side surface of the box door 2, rubber strips are fixedly connected to four sides of each boss, the interior of the box body 1 can be kept sealed better when the box door 2 is closed, cold air leakage is avoided, a plurality of support mechanisms 4 are movably clamped in the box body 1 through a plurality of support mechanisms arranged in the box body, the number of the support mechanisms corresponds to the number of the support plates 4 one to one, and the support plates 4 can, thereby facilitating the taking and storage of the medicine bottles, the support plate 4 is provided with a plurality of placing grooves 5 for placing the medicine bottles, the medicine bottles can be directly placed in the placing grooves 5, so that the stability of the medicine bottles can be ensured, the medicine bottles are prevented from falling down and causing the loss of the medicine, the upper end inside the box body 1 is fixedly connected with a guide plate 6 for guiding the flow direction of the gas, the guide plate 6 is fixedly connected with the inner side wall of the box body 1 and is positioned right above the support plate 4, when the air pump 8 works, the gas can pass through the front part of the guide plate 6 (the end of the guide plate 6 close to the box door 2 is the front part, as shown in figure 2), so that the gas can not directly move from the medicine bottles to the direction of the air exhaust opening, thereby the influence of the air flow generated by the air pump 8 when working on the medicine in the medicine bottles can be reduced as much as possible, and the, the transfer chamber 7 is respectively connected with the inside of the box body 1 and the air pump 8, the transfer chamber 7 is communicated with the inside of the box body 1 through a plurality of through holes formed in the side wall of the bottom of the transfer chamber 7, when the air pump 8 pumps air, air in the box body 1 can enter the transfer chamber 7 through the through holes and then is discharged through the air pump 8, the air in the box body 1 can uniformly and slowly enter the transfer chamber 7 through the through holes, the flowing speed of the air in the box body 1 can be reduced as much as possible, and therefore the influence of air flow on medicines is further reduced;

the refrigeration equipment is the prior art and is widely applied at present, so the utility model is not described in detail, for example, the refrigerator is widely applied at present;

the refrigeration equipment and the air pump 8 are communicated with an external power supply through cables.

Specifically, the bearing mechanism includes two symmetrical sliding seats 9, the sliding seats 9 are mounted on the inner side wall of the box body 1, the sliding seats 9 include a first outer frame 901 and a second outer frame 902, the first outer frame 901 and the second outer frame 902 are both provided with a "convex" groove, the convex part of the "convex" groove respectively penetrates through the side walls of the first outer frame 901 and the second outer frame 902 and is communicated with the outside, the first outer frame 901 and the second outer frame 902 are respectively connected with a T-shaped rod 904 in a sliding manner through a pulley 903 arranged inside, the upper and lower sides of the inside of the outer end of the first outer frame 901 and the second outer frame 902 are both rotatably connected with the pulley 903, the end with small width of the T-shaped rod 904 is located between the two pulleys 903, so that the T-shaped rod 904 can stably slide, the end of the first outer frame 901 and the end of the second outer frame 902 close to the box door 2 are the outer ends, the first outer, the second outer frame 902 is fixedly connected with a T-shaped rod 904 inside the first outer frame 901, a connecting rod is fixedly connected to the T-shaped rod 904 inside the first outer frame 901, the connecting rod extends to the outside of the first outer frame 901 through a convex groove and is fixedly connected with the second outer frame 902, a bearing plate 905 is fixedly connected to the outer side of the T-shaped rod 904 inside the second outer frame 902, a connecting rod is fixedly connected to the T-shaped rod 904 inside the second outer frame 902, the connecting rod extends to the outside of the second outer frame 902 through the convex groove and is fixedly connected with the bearing plate 905, the bearing plate 905 is movably clamped with the supporting plate 4, and the two bearing plates 905 can stably support the supporting plate 4, so that the supporting plate 4 can stably support medicines;

the one end length that T shape pole 904 width is little equals with the one end length that the width is big (be half of first frame 901 and second frame 902 length), T shape pole 904 still has half length to be located the inside of the first frame 901 and the second frame 902 that correspond when following the roll-off in first frame 901 and the second frame 902 respectively, thereby make the second frame 902 and the more stable slip of loading board 905 with two T shape pole 904 interconnect respectively, then make the stable slip of layer board 4, prevent that the medicine from producing to jolt and causing unrestrained.

Specifically, a plurality of square grooves 906 are formed in the bearing plates 905, a plurality of square rods 907 matched with the square grooves 906 are fixedly connected to two side faces of the supporting plate 4, when the supporting plate 4 is placed on the two bearing plates 905, the square rods 907 can be inserted into the corresponding square grooves 906, and therefore the supporting plate 4 can be directly pulled to move to the outside of the box body 1 (as shown in fig. 7), and then medicine bottles containing medicines can be taken and placed conveniently.

Particularly, the downside outer end fixedly connected with arm-tie 24 of layer board 4, the setting of arm-tie 24 can conveniently stimulate layer board 4, the equal fixedly connected with landing leg 25 in downside four corners of layer board 4, the lower terminal surface of landing leg 25 flushes with the lower terminal surface of arm-tie 24, can make the steady putting on the desktop of layer board 24.

Example two:

in order to better prevent the medicine inside the medicine bottle on the pallet 4 from spilling when the pallet 4 is pulled out, a clamping frame 11 is provided, specifically, a base 10 is provided above each bearing mechanism, the base 10 is fixedly connected with the inner side wall of the box body 1, the base 10 is in an X shape, four corners of the base are fixedly connected with the inner side wall of the box body 1, certain materials can be saved under the condition that the base 10 is stable, a lifting clamping frame 11 for clamping the bottle cap is arranged below the base 10, the clamping frame 11 can clamp the bottle cap of a medicine bottle for containing medicines, and the clamping frame 11 is controlled by an adjusting bolt 12 engaged and connected with the base 10, the height of the clamping frame 11 can be controlled by rotating the adjusting bolt 12, therefore, the clamping frame 11 with the bottle caps clamped thereon can move downwards to cover the bottle caps on the medicine bottles on the supporting plate 4, and then the medicine in the medicine bottles can be well prevented from spilling.

In order to conveniently place a bottle cap on the clamping frame 11, the clamping frame 11 is detachably arranged, specifically, four corners of the base 10 are slidably connected with sliding rods 13, a spring 14 is connected between the upper end of the sliding rod 13 and the base 10, the upper end of the sliding rod 13 penetrates through the base 10 and is sleeved with the spring 14, the upper end of the spring 14 is fixedly connected with a circular plate fixedly connected with the upper end surface of the sliding rod 13, the lower end of the spring 14 is fixedly connected with the upper side surface of the base 10, the sliding rod 13 can be pushed upwards by the spring 14, the lower end of the sliding rod 13 is fixedly connected with a connecting frame 15, the lower end of the sliding rod 13 penetrates through the base 10 and is connected with the connecting frame 15, the lower ends of two sliding rods 13 located at the same end are fixedly connected with one connecting frame 15, inserting rods 16 matched with the connecting frame 15 are fixedly connected to two sides of the clamping frame 11, the two inserting rods 16 can be respectively inserted into, the inserted link 16 is fixedly connected with a bulge 17, the inner side wall of the connecting frame 15 is provided with an arc groove 18 matched with the bulge 17, and the bulge 17 and the arc groove 18 are in interference fit, so that the inserted link 16 and the connecting frame 15 can be stably connected together;

when the adjusting bolt 12 is rotated clockwise, the adjusting bolt 12 moves downwards to press the clamping frame 11 to drive the connecting frame 15 to move downwards against the elastic force of the spring 14;

when the adjusting bolt 12 is rotated counterclockwise, the adjusting bolt 12 moves upward, and the spring 14 pushes up the connecting frame 15 upward without pressing the clamping frame 11, so that the clamping frame 11 also rises;

by adopting the mode, the clamping frame 11 can be independently taken down, then the bottle cap is placed on the clamping frame 11, and the clamping frame 11 is connected between the two connecting frames 15 through the inserting rod 16, so that the bottle cap can be conveniently placed.

The clamping frame 11 can clamp the bottle cap in the following manner, specifically, a plurality of clamping grooves 19 for placing the bottle cap are formed in the clamping frame 11, the positions and the number of the clamping grooves 19 correspond to the positions and the number of the placing grooves 5 one by one, an empty groove 20 is formed in one side of each clamping groove 19 and located inside the clamping frame 11, an empty groove 20 is formed in the front side of each row of the clamping grooves 19 (the side, away from the refrigeration cavity 3, of each clamping groove 19 is the front side), sliding plates 21 are slidably connected inside the empty grooves 20, the sliding plates 21 can be matched with the groove walls of the clamping grooves 19 to clamp the bottle cap, the sliding plates 21 are connected with each other through connecting rods 22, the connecting rods 22 penetrate through the groove walls between the two adjacent empty grooves 20 to connect the sliding plates 21 together, all the sliding plates 21 can be slid by controlling one sliding plate 21 to slide, the front end faces of the clamping frame 11 are engaged with clamping bolts 23, and the inner ends of the clamping bolts 23 are rotatably connected with the corresponding sliding, the clamping bolt 23 is rotatably connected with the sliding plate 21 through a convex shaft, the arrangement of the convex shaft can enable the clamping bolt 23 to be rotatably connected with the sliding plate 21 but not to be separated from the sliding plate 21, and the sliding plate 21 can be driven to slide in the hollow groove 20 by rotating the clamping bolt 23, so that all the sliding plates 21 can slide.

The arrows shown in fig. 2 represent the direction of air flow inside the tank 1 when the suction pump 8 is operated.

The working principle is as follows: before use, the clamping frame 11 is taken out, then the bottle cap is placed in the clamping groove 19, then the clamping bolt 23 is rotated clockwise, the sliding plate 21 and the groove wall of the clamping groove 19 are matched with each other to clamp the bottle cap, and then the clamping frame 11 is arranged between the two connecting frames 15;

when the medicine bottle freezing and drying device is used, the supporting plate 4 is pulled to the outside of the box body 1, then the medicine bottle is placed in the placing groove 5, then the supporting plate 4 is pushed back to the inside of the box body 1, the box door 2 is closed, then the refrigerating device and the air pump 8 can be started, and the medicine in the medicine bottle is frozen and dried at low temperature;

after freeze-drying is finished, the box door 2 can be opened, the clamping frame 11 descends by clockwise rotating the adjusting bolt 12, the bottle cap covers the medicine bottle, then the clamping bolt 23 is anticlockwise rotated, the bottle cap is not clamped by the groove walls of the sliding plate 21 and the clamping groove 19, then the clamping frame 11 ascends by anticlockwise rotating the adjusting bolt 12, finally the supporting plate 4 is pulled out, the medicine bottle on the supporting plate is taken out, and sealing work can be carried out.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (7)

1. The utility model provides a low temperature freeze-drying equipment for pharmaceutic preparation, includes box (1), the inside refrigeration chamber (3) of opening of back lateral wall of box (1), and the internally mounted of refrigeration chamber (3) has refrigeration plant, the place ahead of box (1) articulates there is chamber door (2), its characterized in that: the utility model discloses a medicine bottle, including box (1), box (1) have a plurality of layer boards (4) through a plurality of bearing mechanism activity joints that its internally mounted has, and it has a plurality of standing grooves (5) that are used for placing the medicine bottle to open on layer board (4), the inside upper end fixedly connected with of box (1) is used for guide gas flow direction's guide plate (6), and the inside of lateral wall is opened on box (1) has transit chamber (7), transit chamber (7) respectively with the inside and aspiration pump (8) interconnect of box (1).

2. A cryolyophilization apparatus for pharmaceutical preparations according to claim 1, wherein: the bearing mechanism comprises two sliding seats (9) which are symmetrical to each other, each sliding seat (9) comprises a first outer frame (901) and a second outer frame (902), the first outer frame (901) and the second outer frame (902) are respectively connected with a T-shaped rod (904) in a sliding mode through a pulley (903) arranged inside, the first outer frame (901) is installed on the inner side wall of the box body (1), the second outer frame (902) is fixedly connected with the T-shaped rod (904) inside the first outer frame (901), a bearing plate (905) is fixedly connected to the outer side of the T-shaped rod (904) inside the second outer frame (902), and the bearing plate (905) is movably connected with the supporting plate (4) in a clamping mode.

3. A cryogenic freeze drying apparatus for pharmaceutical preparations according to claim 2, characterized in that: a plurality of square grooves (906) are formed in the bearing plate (905), and a plurality of square rods (907) matched with the square grooves (906) are fixedly connected to two side faces of the supporting plate (4).

4. A cryolyophilization apparatus for pharmaceutical preparations according to claim 1, wherein: every top of bearing the weight of the mechanism all is equipped with base (10), the inside wall fixed connection of base (10) and box (1), the below of base (10) is equipped with the clamp frame (11) that are used for the centre gripping bottle lid of liftable, and clamp frame (11) are controlled by adjusting bolt (12) that the meshing is connected on base (10).

5. A cryogenic freeze drying apparatus for pharmaceutical preparations according to claim 4, characterized in that: the equal sliding connection in four corners of base (10) has slide bar (13), be connected with spring (14) between the upper end of slide bar (13) and base (10), the lower extreme fixedly connected with connection frame (15) of slide bar (13), both sides fixedly connected with and inserted bar (16) of connection frame (15) looks adaptation of frame (11), fixedly connected with is protruding (17) on inserted bar (16), open arc groove (18) that have with protruding (17) looks adaptation on the inside wall of connection frame (15).

6. A cryogenic freeze drying apparatus for pharmaceutical preparations according to claim 5, characterized in that: open on clamp frame (11) and have a plurality of clamp grooves (19) that are used for placing the bottle lid, and the inside that is located clamp frame (11) in one side of clamp groove (19) is opened and is had dead slot (20), the inside sliding connection of dead slot (20) has slide (21), and passes through connecting rod (22) interconnect between a plurality of slide (21), and the preceding terminal surface meshing of clamp frame (11) is connected with clamping bolt (23), the inner of clamping bolt (23) rotates with slide (21) that correspond and is connected.

7. A cryolyophilization apparatus for pharmaceutical preparations according to claim 1, wherein: the outer end of the lower side surface of the supporting plate (4) is fixedly connected with a pulling plate (24), and four corners of the lower side surface of the supporting plate (4) are fixedly connected with supporting legs (25).

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