CN212800316U - Multi-sample universal nucleic acid extractor - Google Patents
Multi-sample universal nucleic acid extractor Download PDFInfo
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- CN212800316U CN212800316U CN202021455735.0U CN202021455735U CN212800316U CN 212800316 U CN212800316 U CN 212800316U CN 202021455735 U CN202021455735 U CN 202021455735U CN 212800316 U CN212800316 U CN 212800316U
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- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 42
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 42
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 42
- 238000000605 extraction Methods 0.000 claims abstract description 54
- 230000001954 sterilising effect Effects 0.000 claims abstract description 18
- 238000009423 ventilation Methods 0.000 claims abstract description 13
- 239000011248 coating agent Substances 0.000 claims abstract description 9
- 238000000576 coating method Methods 0.000 claims abstract description 9
- 230000007246 mechanism Effects 0.000 claims description 15
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 3
- 229910052709 silver Inorganic materials 0.000 claims description 3
- 239000004332 silver Substances 0.000 claims description 3
- 239000000284 extract Substances 0.000 claims 1
- 230000002070 germicidal effect Effects 0.000 abstract description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 239000007788 liquid Substances 0.000 description 4
- 238000007789 sealing Methods 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 238000013461 design Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 208000005623 Carcinogenesis Diseases 0.000 description 1
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 208000019155 Radiation injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000004500 asepsis Methods 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036952 cancer formation Effects 0.000 description 1
- 231100000504 carcinogenesis Toxicity 0.000 description 1
- 230000006037 cell lysis Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 208000016361 genetic disease Diseases 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
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Abstract
The utility model provides a general type nucleic acid extraction appearance of many samples, including extraction appearance body, control panel and ventilation hole, the outside of extraction appearance body is rotated and is connected with the apron, and wherein the outside intermediate position department of apron is provided with the observation window, the outside below of apron is provided with the fixed block, the ventilation hole has been seted up to one side of extraction appearance body, the opposite side of extraction appearance body is connected with the control panel through the connecting rod. The utility model discloses in, through setting up ultraviolet sterilizing lamp, reflection of light strip and seal baffle, before the extraction appearance uses, can control ultraviolet sterilizing lamp through the control panel, then carry out germicidal treatment through ultraviolet sterilizing lamp to the inside of extraction appearance, prevent to pollute the nucleic acid, the coating has silver-colored coating on the reflection of light strip simultaneously, can be used to reflect the ultraviolet ray that ultraviolet sterilizing lamp produced to can guarantee constantly to extract the inside omnidirectional of appearance and carry out germicidal treatment, guarantee to extract appearance internal environment and guarantee aseptically.
Description
Technical Field
The utility model relates to a nucleic acid extraction appearance field especially relates to a general type nucleic acid extraction appearance of many samples.
Background
The research of nucleic acid is an important subject in modern biology and medical research, and the nucleic acid is used as a carrier of genetic information, is a material basis of gene expression, has very important functions in the normal growth, development, reproduction and other life activities of organisms, and has close relation with abnormal conditions of life (such as tumorigenesis, radiation injury, genetic diseases and the like);
the nucleic acid extractor is an instrument for automatically finishing the extraction of sample nucleic acid by using matched nucleic acid extraction reagents, and is divided into two types, wherein one type is large-scale automatic and is generally called as an automatic liquid workstation, and the other type is a small-sized automatic nucleic acid extractor, and the extraction and purification process is automatically finished by using the packaged matched reagents; the large automatic liquid workstation is suitable for extracting thousands of samples of the same kind at one time due to high equipment cost and high operation cost, and has less application rate; small automated instruments are increasingly used because of the low cost of instrumentation and operation.
But because current multiple sample commonality nucleic acid extraction appearance when using, still has some weak points, and nucleic acid extraction appearance is comparatively strict to its inside sterile environment requirement, if its inside contains the bacterium, then can influence the effect when extracting the detection and utilizing nucleic acid, nevertheless current nucleic acid extraction appearance still has some defects to its inside sterile environment, also has certain not enough in the aspect of the ventilation simultaneously, for this reason the utility model provides a multiple sample general type nucleic acid extraction appearance solves above-mentioned problem.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a general type nucleic acid extraction appearance of many samples to solve above-mentioned technical problem.
The utility model discloses a solve above-mentioned technical problem, adopt following technical scheme to realize: the utility model provides a general type nucleic acid extraction appearance of many samples, includes and draws appearance body, control screen and ventilation hole, its characterized in that: the external side of the extraction instrument body is rotatably connected with a cover plate, an observation window is arranged in the middle position of the external side of the cover plate, a fixed block is arranged below the external side of the cover plate, one side of the extraction instrument body is provided with a vent hole, and the other side of the extraction instrument body is connected with a control screen through a connecting rod;
the magnetic force frame is arranged inside the extraction instrument body, the magnetic bar sleeve frame is also arranged inside the extraction instrument body and is positioned below the magnetic force frame, a plurality of magnetic bars are arranged on the bottom of the magnetic force frame, a plurality of magnetic bar sleeves are arranged on the magnetic bar sleeves, and the plurality of magnetic bar sleeves are vertically arranged on the bottom of the magnetic bar sleeve frame;
the ultraviolet sterilization lamp extractor is characterized by further comprising a positioning mechanism, wherein the positioning mechanism is arranged at the middle position of the bottom of the extractor body, an ultraviolet sterilization lamp is arranged at the top of the inner side of the extractor body, sealing baffles are slidably connected to the two sides of the inner portion of the extractor body, the upper ends and the lower ends of the sealing baffles are slidably connected to the inner side of the extractor body through sliders, and reflective strips are arranged on the outer sides of the sealing baffles.
Preferably, the plurality of magnetic rod sleeves are positioned right below the plurality of magnetic rods, and every two magnetic rod sleeves can be sleeved and connected.
Preferably, the number of the plurality of magnetic rod sleeves is the same as the number of the plurality of magnetic rods.
Preferably, positioning mechanism includes fixed frame, puts thing groove, deep hole board and deep hole pipe, the thing groove has been seted up to the inboard of fixed frame, put the inside equidistant a plurality of deep hole boards of having placed of thing groove, all be provided with a plurality of deep hole pipes on every deep hole board.
Preferably, the bottom of the inner side of the storage groove is provided with a top plate, one end of the top plate is connected with a handle, and the handle penetrates through a sliding groove formed in the fixing frame.
Preferably, the surface of the reflective strip is coated with a silver coating.
Compared with the prior art, the utility model provides a pair of general type nucleic acid extraction appearance of many samples has following beneficial effect:
the utility model provides a general type nucleic acid extraction appearance of many samples, at first, through setting up the ultraviolet sterilizing lamp, reflection of light strip and seal baffle, before the extraction appearance uses, can control the ultraviolet sterilizing lamp through the control panel, then carry out germicidal treatment through the ultraviolet sterilizing lamp to the inside of extraction appearance, prevent polluting nucleic acid, the coating has silver-colored coating on the reflection of light strip simultaneously, can be used for reflecting the ultraviolet ray that the ultraviolet sterilizing lamp produced, thereby can be to the inside omnidirectional of extraction appearance sterilization treatment, guarantee that the inside environment of extraction appearance guarantees aseptically constantly, the ventilation hole has been seted up to the inboard of seal baffle simultaneously, and the ventilation hole has all been seted up to the inboard both ends face of extraction appearance body, can realize the ventilation requirement to the inside of extraction appearance, when nucleic acid detects, block the ventilation hole with seal baffle and can prevent that outside bacterium from getting into, the flexibility is stronger;
secondly, through having placed a plurality of deep hole boards on fixed frame, all be provided with a plurality of deep hole pipes on every deep hole board, consequently can place a plurality of nucleic acid reagents simultaneously, improve the work efficiency that nucleic acid drawed the detection greatly, set up the roof in the inboard bottom of fixed frame simultaneously, and one side of roof is connected with the handle, it slides in the spout to drive the handle, can be ejecting with deep hole board and deep hole pipe, thereby can be quick take out the kit, moreover, the steam generator is simple in structure, and reasonable design greatly accelerates work efficiency.
Drawings
FIG. 1 is a schematic structural view of a multi-sample general nucleic acid extractor of the present invention;
FIG. 2 is a schematic view of the internal structure of the extractor body of the present invention;
fig. 3 is a schematic view of a plane of depression structure of the positioning mechanism of the present invention;
fig. 4 is a side sectional view of the positioning mechanism of the present invention;
reference numerals: 1. an extraction instrument body; 2. an observation window; 3. a cover plate; 4. a control screen; 5. a fixed block; 6. a vent hole; 7. an ultraviolet sterilizing lamp; 8. a magnetic frame; 9. a magnetic bar; 10. a magnetic bar sleeve frame; 11. a magnetic rod sleeve; 12. a slider; 13. a light-reflecting strip; 14. sealing the baffle; 15. a positioning mechanism; 151. a fixing frame; 152. a storage groove; 153. a deep hole plate; 154. a deep hole tube; 155. a top plate; 156. a chute; 157. a handle.
Detailed Description
In order to make the technical means, the creation features, the achievement purposes and the functions of the present invention easy to understand, the present invention will be further explained below with reference to the following embodiments and the accompanying drawings, but the following embodiments are only the preferred embodiments of the present invention, and not all embodiments are included. Based on the embodiments in the implementation, other embodiments obtained by those skilled in the art without any creative efforts belong to the protection scope of the present invention.
The following describes an embodiment of the present invention with reference to the accompanying drawings, please refer to fig. 1, fig. 2, fig. 3 and fig. 4, wherein fig. 1 is a schematic structural diagram of a multi-sample general nucleic acid extracting apparatus of the present invention; FIG. 2 is a schematic view of the internal structure of the extractor body of the present invention; fig. 3 is a schematic view of a plane of depression structure of the positioning mechanism of the present invention; fig. 4 is a side sectional view of the positioning mechanism of the present invention.
In the specific implementation process, as shown in fig. 1-4, a multi-sample general nucleic acid extractor comprises an extractor body 1, a control screen 4 and a vent 6, and is characterized in that: the outer side of the extraction instrument body 1 is rotatably connected with a cover plate 3, an observation window 2 is arranged in the middle position of the outer side of the cover plate 3, a fixed block 5 is arranged below the outer side of the cover plate 3, a vent hole 6 is formed in one side of the extraction instrument body 1, and the other side of the extraction instrument body 1 is connected with a control screen 4 through a connecting rod; the magnetic extraction instrument further comprises a magnetic rack 8, magnetic rods 9, a magnetic rod sleeve rack 10 and magnetic rod sleeves 11, wherein the magnetic rack 8 is arranged inside the extraction instrument body 1, the magnetic rod sleeve rack 10 is also arranged inside the extraction instrument body 1, the magnetic rod sleeve rack 10 is positioned below the magnetic rack 8, a plurality of magnetic rods 9 are arranged, the magnetic rods 9 are vertically arranged at the bottom of the magnetic rack 8, the magnetic rod sleeves 11 are arranged, and the magnetic rod sleeves 11 are vertically arranged at the bottom of the magnetic rod sleeve rack 10; wherein still including positioning mechanism 15, positioning mechanism 15 sets up in the bottom intermediate position department that draws appearance body 1, and the inboard top of drawing appearance body 1 is provided with ultraviolet sterilizing lamp 7, and the inside both sides sliding connection who draws appearance body 1 has seal baffle 14, and wherein seal baffle 14's upper and lower both ends are passed through slider 12 sliding connection and are being drawn the inboard of appearance body 1, and seal baffle 14's the outside is provided with reflection of light strip 13.
In the specific implementation process, as shown in fig. 2, the plurality of magnetic rod sleeves 11 are located right below the plurality of magnetic rods 9, and every two magnetic rods can be sleeved and connected.
In the specific implementation process, as shown in fig. 2, the number of the plurality of magnetic rod sleeves 11 is the same as that of the plurality of magnetic rods 9.
In the specific implementation process, as shown in fig. 3-4, the positioning mechanism 15 includes a fixing frame 151, an object placing groove 152, a deep hole plate 153 and a deep hole pipe 154, the object placing groove 152 is opened on the inner side of the fixing frame 151, the deep hole plates 153 are placed in the object placing groove 152 at equal intervals, and each deep hole plate 153 is provided with a plurality of deep hole pipes 154.
In a specific implementation process, as shown in fig. 3-4, the positioning mechanism 15 includes a fixed frame 151, an object placing groove 152, a deep hole plate 153 and a deep hole pipe 154, the object placing groove 152 is formed on the inner side of the fixed frame 151, the plurality of deep hole plates 153 are placed in the object placing groove 152 at equal intervals, and each deep hole plate 153 is provided with the plurality of deep hole pipes 154; the bottom of the inner side of the storage trough 152 is provided with a top plate 155, wherein one end of the top plate 155 is connected with a handle 157, and the handle 157 penetrates through a sliding slot 156 arranged on the fixed frame 151.
In a specific implementation, as shown in fig. 2, the surface of the reflective strips 13 is coated with a silver coating.
The working principle of the utility model is as follows:
the nucleic acid extractor has the same principle as the traditional instrument, controls extraction operation through a control screen 4, moves magnetic beads with adsorbed nucleic acid to different reagent tanks by using a magnetic rod 9 on a magnetic rack 8 in a machine, repeatedly and rapidly stirs liquid by using a magnetic rod sleeve 11 sleeved on the outer layer of the magnetic rod 9 to uniformly mix the liquid, and finally obtains high-purity DNA/RNA nucleic acid molecules through cell lysis, nucleic acid adsorption, cleaning and extraction.
The utility model provides a general type nucleic acid extraction appearance of many samples, at first, through setting up ultraviolet sterilizing lamp 7, reflection of light strip 13 and seal baffle 14, before the extraction appearance uses, can control ultraviolet sterilizing lamp 7 through control panel 4, then carry out germicidal treatment to the inside of extraction appearance through ultraviolet sterilizing lamp 7, prevent polluting nucleic acid, the coating has silver-colored coating on reflection of light strip 13 simultaneously, can be used for reflecting the ultraviolet ray that ultraviolet sterilizing lamp 7 produced, thereby can carry out germicidal treatment to the extraction appearance inside omnidirectional, guarantee that the internal environment of extraction appearance guarantees asepsis constantly, seal baffle 14's inboard has seted up ventilation hole 6 simultaneously, and the inboard both ends face of extraction appearance body 1 has all seted up ventilation hole 6, can realize the ventilation requirement to the extraction appearance inside, when nucleic acid detects, block ventilation hole 6 and can prevent that outside bacterium from getting into with seal baffle 14, the flexibility is stronger, secondly, through having placed a plurality of deep hole boards 153 on fixed frame 151, all be provided with a plurality of deep hole pipes 154 on every deep hole board 153, consequently, can place a plurality of nucleic acid reagents simultaneously, improve the work efficiency that nucleic acid drawed the detection greatly, set up roof 155 simultaneously in the inboard bottom of fixed frame 151, and one side of roof 155 is connected with handle 157, drive handle 157 and slide in spout 156, can be ejecting with deep hole board 153 and deep hole pipe 154, thereby can be quick take out the kit, moreover, the steam generator is simple in structure, and reasonable design, and the work efficiency is greatly accelerated.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It should be understood by those skilled in the art that the present invention is not limited by the above embodiments, and the description in the above embodiments and the description is only preferred examples of the present invention, and is not intended to limit the present invention, and that the present invention can have various changes and modifications without departing from the spirit and scope of the present invention, and these changes and modifications all fall into the scope of the claimed invention. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (6)
1. The utility model provides a general type nucleic acid extraction appearance of many samples, includes and draws appearance body (1), control panel (4) and ventilation hole (6), its characterized in that: the external side of the extraction instrument body (1) is rotatably connected with a cover plate (3), wherein an observation window (2) is arranged in the middle position of the external side of the cover plate (3), a fixed block (5) is arranged below the external side of the cover plate (3), a vent hole (6) is formed in one side of the extraction instrument body (1), and the other side of the extraction instrument body (1) is connected with a control screen (4) through a connecting rod;
the magnetic extraction instrument is characterized by further comprising a magnetic frame (8), magnetic rods (9), a magnetic rod sleeve frame (10) and magnetic rod sleeves (11), wherein the magnetic frame (8) is arranged inside the extraction instrument body (1), the magnetic rod sleeve frame (10) is also arranged inside the extraction instrument body (1), the magnetic rod sleeve frame (10) is located below the magnetic frame (8), the magnetic rods (9) are arranged in plurality, the magnetic rods (9) are vertically arranged at the bottom of the magnetic frame (8), the magnetic rod sleeves (11) are arranged in plurality, and the magnetic rod sleeves (11) are vertically arranged at the bottom of the magnetic rod sleeve frame (10);
wherein still including positioning mechanism (15), positioning mechanism (15) set up the bottom intermediate position department of extracting appearance body (1), the inboard top of extracting appearance body (1) is provided with ultraviolet sterilizing lamp (7), the inside both sides sliding connection who extracts appearance body (1) has seal baffle (14), and wherein the upper and lower both ends of seal baffle (14) pass through slider (12) sliding connection in the inboard of extracting appearance body (1), the outside of seal baffle (14) is provided with reflection of light strip (13).
2. The universal nucleic acid extractor of claim 1, wherein: the magnetic rod sleeves (11) are positioned right below the magnetic rods (9) and can be connected in a sleeved mode between every two magnetic rods.
3. The universal nucleic acid extractor of claim 2, wherein: the number of the plurality of magnetic rod sleeves (11) is the same as that of the plurality of magnetic rods (9).
4. The universal nucleic acid extractor of claim 1, wherein: positioning mechanism (15) include fixed frame (151), put thing groove (152), deep hole board (153) and deep hole pipe (154), put thing groove (152) have been seted up to the inboard of fixed frame (151), put the inside of thing groove (152) and equidistant a plurality of deep hole board (153) of having placed, all be provided with a plurality of deep hole pipes (154) on every deep hole board (153).
5. The universal nucleic acid extractor of claim 4, wherein: the bottom of the inner side of the storage groove (152) is provided with a top plate (155), one end of the top plate (155) is connected with a handle (157), and the handle (157) penetrates through a sliding groove (156) formed in the fixing frame (151).
6. The universal nucleic acid extractor of claim 1, wherein: the surface of the light reflecting strip (13) is coated with a silver coating.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021455735.0U CN212800316U (en) | 2020-07-22 | 2020-07-22 | Multi-sample universal nucleic acid extractor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021455735.0U CN212800316U (en) | 2020-07-22 | 2020-07-22 | Multi-sample universal nucleic acid extractor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN212800316U true CN212800316U (en) | 2021-03-26 |
Family
ID=75102512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021455735.0U Active CN212800316U (en) | 2020-07-22 | 2020-07-22 | Multi-sample universal nucleic acid extractor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN212800316U (en) |
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2020
- 2020-07-22 CN CN202021455735.0U patent/CN212800316U/en active Active
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| Date | Code | Title | Description |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: Room 501, Building A, Jianye Building, No. 96 Xiangxing Road, Xiang'an Industrial Zone, Xiamen Torch High tech Zone, Fujian Province, 361000 Patentee after: Kaishuo Biotechnology (Xiamen) Co.,Ltd. Address before: Room 501, block a, Jianye Building, No.96, Xiangxing Road, industrial zone, torch high tech Zone (Xiang'an), Xiamen City, Fujian Province Patentee before: KAISHUO BIO-TECH (XIAMEN) Co.,Ltd. |
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| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: A universal nucleic acid extraction instrument with multiple samples Effective date of registration: 20231103 Granted publication date: 20210326 Pledgee: Industrial Bank Limited by Share Ltd. Xiamen branch Pledgor: Kaishuo Biotechnology (Xiamen) Co.,Ltd. Registration number: Y2023980064143 |