CN212791024U - A solvent dropwise add device for grinding method preparation medicine eutectic - Google Patents
A solvent dropwise add device for grinding method preparation medicine eutectic Download PDFInfo
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- CN212791024U CN212791024U CN202021199439.9U CN202021199439U CN212791024U CN 212791024 U CN212791024 U CN 212791024U CN 202021199439 U CN202021199439 U CN 202021199439U CN 212791024 U CN212791024 U CN 212791024U
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- storage tank
- sample
- sample storage
- level sensor
- grinding method
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- 238000000034 method Methods 0.000 title claims abstract description 18
- 239000002904 solvent Substances 0.000 title claims abstract description 16
- 239000003814 drug Substances 0.000 title claims description 7
- 230000005496 eutectics Effects 0.000 title claims description 7
- 238000002360 preparation method Methods 0.000 title claims description 7
- 238000003860 storage Methods 0.000 claims abstract description 39
- 239000007788 liquid Substances 0.000 claims abstract description 9
- 238000011160 research Methods 0.000 description 7
- 239000000463 material Substances 0.000 description 5
- 238000012824 chemical production Methods 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000003913 materials processing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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Abstract
The utility model discloses a solvent dripping device for preparing pharmaceutical cocrystal by a grinding method, which comprises a base, a stand column, a clamp, a sample storage tank, a pressurizing device and a control device; the sample storage tank is provided with a plug sample inlet and a pressure release port, the pressure release port is provided with an electromagnetic valve, the inner wall of the sample storage tank is provided with a liquid level sensor, the electromagnetic valve and the liquid level sensor are both electrically connected with the control device, the bottom end of the sample storage tank is provided with a discharge port, and the discharge port is provided with a one-way valve; adopt sealed storage appearance jar as the sample carrier, thereby the speed time of effective control application of sample is as application of sample power device to compressed air source, and set up level sensor and pressure release mouth's solenoid valve in storage appearance jar and carry out feedback control, thereby can control compressed air source to close through level sensor feedback to controlling means and stop the pressurization after reaching application of sample volume demand, and open the balanced internal and external pressure of pressure release mouth, reach accurate application of sample demand, and saved the human cost input greatly, this simple structure is with low costs and easy to maintain, be fit for the laboratory and extensively use widely.
Description
Technical Field
The utility model relates to a chemical industry test equipment technical field, in particular to a solvent dropwise add device that is used for abrasive process preparation medicine eutectic.
Background
In the research of daily chemical production or laboratory, often need control the addition and the rate of addition of certain reaction raw materials in order to satisfy the reaction demand, among the prior art, daily chemical production adopts large-scale automatic material conveying ware to handle more, but in laboratory research, to a small amount of raw materials processing, the automatic material conveying ware is used still less, mainly because the cost of automatic material conveying ware is high, can't use widely on a large scale in the laboratory. Therefore, manual control feeding is mostly adopted in small-scale tests of colleges and universities or scientific research institutions.
Scientific research teaches high-efficient accuracy nature, adopt the means of manual control feeding volume and time, need consume a large amount of time and energy and monitor and operate the interpolation of material, and manual control is difficult to ensure reinforced accuracy, seriously influenced the promotion of scientific research efficiency and be difficult to ensure the scientific research accuracy, be unfavorable for the progress development of science and technology, and high accuracy automatic material conveying ware among the prior art can't extensively use in the laboratory because of its with high costs and maintenance cost is also higher, the promotion of scientific research process has seriously been hindered.
Therefore, how to provide an automatic sample adding device with low cost, simple structure and convenient use is a problem to be solved urgently by those skilled in the art.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model provides a solvent dropwise add device for grinding method preparation medicine eutectic adopts pneumatic control and flow valve to combine, makes the automation of adding appearance in the experimentation and more accurate, and this simple structure easily operates, and the maintenance cost is low.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
a solvent dropwise add device for grinding method preparation medicine eutectic includes: the sample storage device comprises a base, a vertical column vertically arranged on one side of the base, a clamp slidably arranged on the vertical column, a sample storage tank clamped in the clamp, a pressurizing device connected with the sample storage tank through a pipeline and a control device electrically connected with the pressurizing device;
the sample storage tank is provided with a sample inlet and a pressure release port, the pressure release port is provided with an electromagnetic valve, the inner wall of the sample storage tank is provided with a liquid level sensor, and the electromagnetic valve and the liquid level sensor are both electrically connected with the control device;
the sample storage tank bottom is provided with the discharge gate, and discharge gate department is provided with the check valve.
Preferably, the device further comprises a clamp lifting device;
the fixture lifting device comprises a stepping motor fixed on the base, a shaft of the stepping motor is connected with a lead screw parallel to the stand column, the lead screw penetrates through the fixture and is connected with the fixture through a lead screw nut, and a limiting block is arranged at the top end of the lead screw.
Preferably, the sample storage tank is a transparent tank body, and scales are arranged on the surface of the tank body.
Preferably, an electromagnetic flow valve is connected below the one-way valve, and the electromagnetic flow valve is electrically connected with the control device.
Preferably, the pressurizing device is a compressed air source, and the compressed air source is connected with the sample storage tank through a flexible pipeline.
Preferably, the outer wall of the sample storage tank is provided with a groove matched with the clamp.
Via the above-mentioned technical scheme, compared with the prior art, the utility model provides a solvent dropwise add device for abrasive process preparation medicine eutectic, adopt sealed storage appearance jar as the sample carrier, use compressed air source as application of sample power device, thereby the speed time of effective control application of sample through the pressurization pressure of control compressed air source, and set up level sensor and relief port's solenoid valve in storage appearance jar and carry out feedback control, thereby can close to stop the pressurization through level sensor feedback to controlling means to control compressed air source after reaching application of sample volume demand, and open the balanced internal and external pressure of relief port, reach accurate application of sample demand, and saved the human cost input greatly, this simple structure is with low costs and easy to maintain, be fit for the laboratory and extensively use widely.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a drawing showing an overall structure of a solvent dropping device for preparing pharmaceutical co-crystals by a grinding method according to embodiment 1 of the present invention;
fig. 2 is a drawing showing a structure diagram of a sample storage tank of a solvent dripping device for preparing pharmaceutical cocrystal by a grinding method in embodiment 1 of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Example 1
As shown in fig. 1, a solvent dropping device for preparing pharmaceutical co-crystals by a grinding method comprises: the sample storage device comprises a base 1, a vertical column 2 vertically arranged on one side of the base 1, a clamp 3 slidably arranged on the vertical column, a sample storage tank 4 clamped in the clamp 3, a pressurizing device 5 connected with the sample storage tank 4 through a pipeline and a control device 6 electrically connected with the pressurizing device 5;
the sample storage tank 4 is provided with a sample inlet 41 and a pressure release port 42, the pressure release port 42 is provided with an electromagnetic valve 43, the inner wall of the sample storage tank 4 is provided with a liquid level sensor 44, and both the electromagnetic valve 43 and the liquid level sensor 44 are electrically connected with the control device 6;
the bottom end of the sample storage tank 4 is provided with a discharge hole 45, and the discharge hole 45 is provided with a one-way valve 46.
The principle of the technical scheme is as follows: when the sample is required to be added, the device is assembled and installed, a required sample is added into the sample storage tank 4 after the completion, in the sample adding process, the pressure range of the pressurizing device 5 is adjusted through the control device 6, so that the required amount of the sample is controlled to flow out of the one-way valve 46 and the outflow time and flow rate are controlled, after the liquid level sensor 44 senses that the required amount of the added sample is reached, the required amount of the sample is fed back to the control device 6, the control device 6 controls the pressurizing device 5 to stop running, and meanwhile, the electromagnetic valve 43 is opened to release pressure so as to balance the inside and the outside.
In some technical schemes, the device further comprises a clamp lifting device;
the fixture lifting device comprises a stepping motor 71 fixed on the base 1 and a screw rod 72 connected with the stepping motor 71 through a shaft and parallel to the upright post 2, the screw rod 72 penetrates through the fixture 3 and is connected with the fixture 3 through a screw rod nut 73, and the top end of the screw rod 72 is provided with a limit block 74.
The principle of the technical scheme is as follows: the lifting device can control the height of the sample storage tank 4 to meet the sample adding requirements of different containers.
In some technical schemes, the sample storage tank 4 is a transparent tank body with scales on the surface, so that the sample adding amount can be observed conveniently.
In some technical solutions, an electromagnetic flow valve 47 is connected below the check valve 46, and the electromagnetic flow valve 47 is electrically connected with the control device 6.
The principle of the technical scheme is as follows: the electromagnetic flow valve 47 also controls the flow rate and the flow velocity, and is used in conjunction with the pressurizing device 5, the level sensor 44, and the like, to more effectively and accurately control the sample addition amount, and to strictly control the sample addition amount when the pressure of the pressurizing device 5 is unstable, thereby avoiding errors.
In some embodiments, the pressurizing device 5 is a compressed air source, and the compressed air source is connected to the sample storage tank 4 through a flexible pipeline 8.
In some technical schemes, the outer wall of the sample storage tank 4 is provided with a groove 48 matched with the clamp 3, so that the sample storage tank 4 is convenient to clamp and is prevented from slipping.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (6)
1. A solvent dropwise add device for grinding method preparation medicine eutectic which characterized in that includes: the sample storage device comprises a base, a vertical column vertically arranged on one side of the base, a clamp slidably arranged on the vertical column, a sample storage tank clamped in the clamp, a pressurizing device connected with the sample storage tank through a pipeline and a control device electrically connected with the pressurizing device;
the sample storage tank is provided with a sample inlet and a pressure release port, the pressure release port is provided with an electromagnetic valve, the inner wall of the sample storage tank is provided with a liquid level sensor, and the electromagnetic valve and the liquid level sensor are both electrically connected with the control device;
the sample storage tank bottom is provided with the discharge gate, and discharge gate department is provided with the check valve.
2. The solvent dripping device for preparing pharmaceutical cocrystal by grinding method according to claim 1, further comprising a fixture lifting device;
the fixture lifting device comprises a stepping motor fixed on the base, a shaft of the stepping motor is connected with a lead screw parallel to the stand column, the lead screw penetrates through the fixture and is connected with the fixture through a lead screw nut, and a limiting block is arranged at the top end of the lead screw.
3. The solvent dripping device for preparing pharmaceutical cocrystals by a grinding method according to claim 1, wherein the sample storage tank is a transparent tank body, and the surface of the tank body is provided with scales.
4. The solvent dripping device for preparing pharmaceutical cocrystal by grinding method according to claim 1, wherein an electromagnetic flow valve is connected under the one-way valve, and the electromagnetic flow valve is electrically connected with the control device.
5. The solvent dripping device for preparing pharmaceutical cocrystal by grinding according to claim 1, wherein the pressurizing device is a compressed air source, and the compressed air source is connected with the sample storage tank through a flexible pipeline.
6. The solvent dripping device for preparing pharmaceutical cocrystal by grinding according to claim 1, wherein the outer wall of the sample storage tank is provided with a groove matched with the clamp.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021199439.9U CN212791024U (en) | 2020-06-24 | 2020-06-24 | A solvent dropwise add device for grinding method preparation medicine eutectic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021199439.9U CN212791024U (en) | 2020-06-24 | 2020-06-24 | A solvent dropwise add device for grinding method preparation medicine eutectic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN212791024U true CN212791024U (en) | 2021-03-26 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021199439.9U Expired - Fee Related CN212791024U (en) | 2020-06-24 | 2020-06-24 | A solvent dropwise add device for grinding method preparation medicine eutectic |
Country Status (1)
| Country | Link |
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| CN (1) | CN212791024U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114405422A (en) * | 2022-01-19 | 2022-04-29 | 中国工程物理研究院激光聚变研究中心 | Fluid shaping device and method for preparing large-diameter polymer microspheres |
-
2020
- 2020-06-24 CN CN202021199439.9U patent/CN212791024U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114405422A (en) * | 2022-01-19 | 2022-04-29 | 中国工程物理研究院激光聚变研究中心 | Fluid shaping device and method for preparing large-diameter polymer microspheres |
| CN114405422B (en) * | 2022-01-19 | 2023-02-28 | 中国工程物理研究院激光聚变研究中心 | Fluid shaping device and method for preparing large-diameter polymer microspheres |
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210326 |