CN212741291U - Nucleic acid in situ hybridization is with scanning support - Google Patents
Nucleic acid in situ hybridization is with scanning support Download PDFInfo
- Publication number
- CN212741291U CN212741291U CN202020772747.XU CN202020772747U CN212741291U CN 212741291 U CN212741291 U CN 212741291U CN 202020772747 U CN202020772747 U CN 202020772747U CN 212741291 U CN212741291 U CN 212741291U
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- Prior art keywords
- transparent plate
- block
- plate
- shell
- nucleic acid
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- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 18
- 238000007901 in situ hybridization Methods 0.000 title claims abstract description 17
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 17
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 17
- 238000005192 partition Methods 0.000 claims abstract description 10
- 229920003023 plastic Polymers 0.000 claims abstract description 9
- 239000004033 plastic Substances 0.000 claims abstract description 9
- 239000011521 glass Substances 0.000 claims description 28
- 230000008878 coupling Effects 0.000 claims description 2
- 238000010168 coupling process Methods 0.000 claims description 2
- 238000005859 coupling reaction Methods 0.000 claims description 2
- 238000009396 hybridization Methods 0.000 claims description 2
- 238000010415 tidying Methods 0.000 claims 3
- 230000009286 beneficial effect Effects 0.000 abstract description 6
- 230000000694 effects Effects 0.000 description 12
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 229910000639 Spring steel Inorganic materials 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
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Abstract
The utility model discloses a scanning bracket for nucleic acid in-situ hybridization, the structure of which comprises a transparent plate, a stop block, a partition plate and a slide groove, the design is provided with a dismounting device through the lower side of the transparent plate, the worker firstly places the transparent plate in a shell to ensure that the bottom end of the transparent plate is attached with a movable strip, then the worker presses the plastic blocks at the left and right ends of the transparent plate downwards, when pressing, the movable strip rotates downwards with the transparent plate through a rotating shaft, when rotating, the movable strip rotates through the rotating shaft and a movable block to ensure that the transparent plate is buckled with a buckling block through a groove, thereby fixing the transparent plate in the shell, when dismounting is needed, the worker can press the pressing plates at the two ends, the pressing plates rotate through the movable block and the rotating shaft, the movable strip jacks up the transparent plate through the rotating shaft, thereby replacing the unscanned slide, and achieving the convenient dismounting of, the beneficial effect that the workers do not need to take out one by one when needing to scan a large number of pieces is achieved.
Description
Technical Field
The utility model relates to a scanning support technical field, concretely relates to nucleic acid normal position is scanning support for hybridization.
Background
In situ hybridization refers to a process of hybridizing specifically labeled nucleic acid with a known sequence as a probe with nucleic acid in a cell or tissue section, so as to precisely and quantitatively locate the specific nucleic acid sequence, wherein in situ hybridization can be performed on a cell specimen or a tissue specimen, a slide needs to be placed in a scanning support, and then scanning analysis is performed on the in situ hybridization by using an in situ hybridization instrument.
However, the existing scanning support does not have the function of being capable of being detached more conveniently, so that the problem that workers need to take out the slide piece by piece is caused, the function of arranging and aligning the slide in the scanning support is not achieved, and the problem that the slide is disordered due to collision in the scanning support is caused.
SUMMERY OF THE UTILITY MODEL
Technical problem to be solved
In order to overcome the defects of the prior art, the scanning support for nucleic acid in-situ hybridization is provided, and the problem that an operator needs to take out a slide by taking the slide out of the scanning support due to the fact that the conventional scanning support does not have the dismounting function is solved, and the problem that the slide is disordered due to external factors in the scanning support due to the fact that the conventional scanning support does not have the function of arranging and aligning the slides in the scanning support is solved.
(II) technical scheme
The utility model discloses a following technical scheme realizes: the utility model provides a scanning bracket for nucleic acid in-situ hybridization, which comprises a transparent plate, a partition plate, a baffle, a glass sheet groove, a dismounting device and a finishing strip, wherein the middle end of the top end surface of the transparent plate is provided with a baffle, the front end of the top end surface of the transparent plate is provided with the partition plate, the glass sheet groove is arranged between the partition plates, the dismounting device is positioned at the bottom end of the transparent plate and consists of a shell, a baffle, a movable block, a pressing plate, a buckling block, a movable strip, a rotating shaft and a groove, the lower side of the inner wall of the shell is provided with the baffle, the middle ends of the left end and the right end of the shell are both provided with the movable block, the right end of the movable block is provided with the pressing plate, the middle end of the left end surface of the movable block is provided with the buckling block, the lower side of the front, the shell carries out the lock joint with the transparent plate, both ends all are provided with arrangement strip around the shell, the arrangement strip comprises arrangement board, spring, fixed block, sliding block and slider, the arrangement board carries out spring coupling through spring and shell, arrangement board rear end face middle-end is provided with the fixed block, the sliding block carries out sliding connection through slider and shell.
Furthermore, press the top of the pressure board face and be provided with the antislip strip, press the pressure board and be the arc to thickness is 3 mm.
Further, the slide groove is provided with two rows, one row the slide groove is located the dog front end, another row the slide groove is located the dog rear end to one row is provided with 7 the slide groove, both ends middle-end all is provided with the plastic block about the transparent plate.
Furthermore, the angle of the fixed block towards the top end face is 5 degrees, the angle of the bottom end face of the sliding block is 5 degrees, and the surfaces of the fixed block and the sliding block are smooth.
Furthermore, arrangement board rear end face is provided with two springs, one the spring is located arrangement board rear end face left side, another the spring is located arrangement board rear end face right side to the spring is compression state.
Furthermore, the middle part of the baffle is hollow, and the width of the baffle is 4 mm.
Further, the surface of the movable strip is at the same horizontal position as the surface of the baffle, and the width of the movable strip is 4 mm.
Furthermore, two grooves are formed in the inner side of the shell, and the springs are arranged in the grooves.
Furthermore, the transparent plate is made of glass.
Furthermore, the buckling block is made of plastic.
Furthermore, the arrangement plate is made of plastic.
(III) advantageous effects
Compared with the prior art, the utility model, following beneficial effect has:
1) in order to solve the problem that the existing scanning bracket does not have the function of more simply and conveniently detaching, which causes that a worker needs to take out the scanning bracket one by one, the dismounting device is arranged at the lower side of the transparent plate, the worker firstly places the transparent plate in the shell to enable the bottom end of the transparent plate to be attached to the movable strip, then the worker presses the plastic blocks at the left end and the right end of the transparent plate downwards, the movable strip rotates downwards with the transparent plate through the rotating shaft during pressing, the movable strip rotates with the movable block through the rotating shaft during rotating, the transparent plate is buckled with the buckling block through the groove, so that the transparent plate is fixed in the shell, if the dismounting is needed, the worker can press the pressing plates at the two ends, the pressing plates rotate with the rotating shaft through the movable block, the movable strip jacks up the transparent plate through the rotating shaft, thereby replacing the unscanned glass slides, and achieving the, the beneficial effect that the workers do not need to take out one by one when needing to scan a large number of pieces is achieved.
2) The slide glass arranging and aligning device has no function of arranging and aligning slide glass in a scanning bracket, and leads to the problem of slide glass disorder caused by collision in the scanning bracket, through arranging strips arranged at the front end and the rear end of a shell, a worker places the slide glass in a slide glass groove, when the scanning bracket is replaced and pressed, the slide glass can incline or is not arranged in order, a slide block slides leftwards, the slide block is in sliding fit with a fixed block through a slide block, an arranging plate can be pushed forwards through the angle between the slide block and the fixed block, a spring can deform due to stress during pushing, so as to generate elasticity, the arranging plate can push the protruded slide glass into the slide glass groove in order, when the fixed block and the slide block are smooth in surface, the slide block and the fixed block can slide when the elasticity is automatically contracted, so as to reset, and the slide glass arranging and aligning are achieved, and the beneficial effects of scanning are better.
Drawings
Other features, objects and advantages of the invention will become more apparent upon reading of the detailed description of non-limiting embodiments with reference to the following drawings:
fig. 1 is a schematic structural view of the present invention;
fig. 2 is a schematic front view of the structure of the present invention;
fig. 3 is a left side view structural diagram of the detaching device of the present invention;
fig. 4 is a front sectional structural schematic view of the detaching device of the present invention;
fig. 5 is a schematic view of the top cross-sectional structure of the finishing strip of the present invention.
In the figure: transparent plate-1, stop block-2, partition plate-3, glass sheet groove-4, dismounting device-5, arranging strip-6, shell-51, baffle-52, movable block-53, pressing plate-54, buckling block-55, movable strip-56, rotating shaft-57, groove-58, arranging plate-61, spring-62, fixed block-63, sliding block-64 and sliding block-65.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Referring to fig. 1, 2, 3, 4 and 5, the present invention provides a scanning support for in situ hybridization of nucleic acids: the glass slide dismounting device comprises a transparent plate 1, a stop block 2, a partition plate 3, a glass slide groove 4, a dismounting device 5 and a sorting strip 6, wherein the stop block 2 is arranged at the middle end of the top end face of the transparent plate 1, the partition plate 3 is arranged at the front end of the top end face of the transparent plate 1, the glass slide groove 4 is arranged between the partition plates 3, the dismounting device 5 is positioned at the bottom end of the transparent plate 1, the dismounting device 5 consists of a shell 51, a baffle plate 52, a movable block 53, a pressing plate 54, a buckling block 55, a movable strip 56, a rotating shaft 57 and a groove 58, the baffle plate 52 is arranged on the lower side of the inner wall of the shell 51, the movable blocks 53 are arranged at the middle ends of the left end and the right end of the shell 51, the pressing plate 54 is arranged at the right end of the left end face of the movable block 53, the movable strip 56 is arranged on the lower side of the front, the front end and the rear end of the shell 51 are provided with the arranging strips 6, each arranging strip 6 is composed of an arranging plate 61, a spring 62, a fixing block 63, a sliding block 64 and a sliding block 65, the arranging plate 61 is in spring connection with the shell 51 through the spring 62, the fixing block 63 is arranged at the middle end of the rear end face of the arranging plate 61, and the sliding block 64 is in sliding connection with the shell 51 through the sliding block 65.
The top end face of the pressing plate 54 is provided with an anti-slip strip, the pressing plate 54 is arc-shaped, the thickness of the pressing plate is 3mm, and the anti-slip effect is achieved.
Wherein, slide groove 4 is provided with two rows, one row slide groove 4 is located 2 front ends of dog, another row slide groove 4 is located 2 rear ends of dog to one row is provided with 7 slide groove 4, transparent plate 1 is controlled both ends middle-end and all is provided with the plastic block, has once only scan a plurality of slides and prevents the cracked effect of transparent plate when pressing.
The angle of the fixed block 63 to the top end face is 5 degrees, the angle of the bottom end face of the sliding block 64 is 5 degrees, the surfaces of the fixed block 63 and the sliding block 64 are smooth, and the effect of flexibility in sliding is achieved.
Wherein, arrangement board 61 rear end face is provided with two springs 62, one spring 62 is located arrangement board 61 rear end face left side, another spring 62 is located arrangement board 61 rear end face right side to spring 62 is the compression state, has better reset effect.
The middle of the baffle plate 52 is hollow, and the width of the baffle plate 52 is 4mm, so that the scanning effect is better.
Wherein, the surface of the movable strip 56 is at the same horizontal position with the surface of the baffle 52, and the width of the movable strip 56 is 4mm, which has better uplifting effect.
Wherein, the shell 51 is provided with two grooves on the inner side, and the spring 62 is arranged in the groove, so that the spring has better guiding effect.
Wherein, transparent plate 1 adopts the glass material, better scanning effect.
The buckling block 55 is made of plastic, and has a better durable effect.
Wherein, the arrangement board 61 adopts the plastics material, has better durable effect.
The spring 62 described in this patent is a mechanical part that works by using elasticity, and a part made of elastic material deforms under the action of external force, recovers to the original shape after removing the external force, and is generally made of spring steel, and the types of springs are complex and various, and mainly include a coil spring, a volute spiral spring, a plate spring, a special-shaped spring and the like according to shape division.
The working principle is as follows: the transparent plate 1 is used for placing glass slides, the stop block 2 and the baffle 3 can separately scan the glass slides, the glass slides can be placed in the glass slide grooves 4 in the transparent plate 1 in a classified manner, when a worker needs to scan the glass slides, the glass slides can be placed in the glass slide grooves 4 in the transparent plate 1, then the transparent plate 1 is placed in the shell 51, the bottom end of the transparent plate 1 is attached to the movable strip 56, then the transparent plate 1 is pressed downwards, the rotating shaft 57 rotates downwards with the transparent plate 1 through the movable strip 56, the pressing plate 54 rotates with the rotating shaft 57 through the movable block 53, the groove 58 is inserted into the buckling block 55 while the transparent plate 1 is pressed, so that the transparent plate 1 is fixed, the problem that the transparent plate 1 inclines or the glass slides out can occur when the transparent plate is pressed, the sliding block 65 can slide leftwards through the arranging strip arranged in the shell 51, the sliding block 64 is slidably attached to the fixed block 63, the sliding block 64, make spring 62 produce elasticity because of the atress, can align the slide in the transparent plate 1 and push when will putting up board 61 ejecting, elasticity can reset putting up board 61 when spring 62 loses power, reached and put up the alignment to the slide, and the beneficial effect of better scanning, scan, when scanning back staff need dismantle transparent plate 1 and take out, through pressing down the pressure board, make movable block 53 upwards rotate activity strip 56 through pivot 57, release shell 51 with transparent plate 1, recess 58 and knot piece 55 are undone and are pegged graft when transparent plate 1 upwards is released, reached and advance convenient dismantlement to the scanning support, the beneficial effect that takes out of a slice is not needed when making the staff need scan in a large number.
The basic principle and the main characteristics of the present invention and the advantages of the present invention have been shown and described above, and the present invention uses standard parts that can be purchased from the market, the special-shaped parts can be customized according to the description of the specification and the attached drawings, the specific connection mode of each part is all the conventional means such as bolt and rivet, welding, etc. mature in the prior art, and machinery, parts and equipment are all adopted in the prior art, and the conventional model is added to the conventional connection mode in the prior art, and detailed description is not given here.
It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (8)
1. The utility model provides a nucleic acid normal position hybridization is with scanning support, includes transparent plate (1), dog (2), division board (3) and slide groove (4), its characterized in that still includes: the glass plate comprises a detaching device (5) and arranging strips (6), wherein a stop block (2) is arranged at the middle end of the top end face of the transparent plate (1), a partition plate (3) is arranged at the front end of the top end face of the transparent plate (1), glass sheet grooves (4) are formed between the partition plates (3), the detaching device (5) is positioned at the bottom end of the transparent plate (1), the detaching device (5) consists of a shell (51), a baffle plate (52), a movable block (53), a pressing plate (54), a buckling block (55), a movable strip (56), a rotating shaft (57) and a groove (58), the baffle plate (52) is arranged on the lower side of the inner wall of the shell (51), the movable blocks (53) are arranged at the middle ends of the left end and the right end of the shell (51), the pressing plate (54) is arranged at the right end of the movable block (53), the buckling block (55) is arranged at the middle end of, the utility model discloses a portable electric cooker, including transparent plate (1), movable block (53), shell (51), both ends middle-end all are provided with recess (58) about transparent plate (1), shell (51) carry out the lock joint with transparent plate (1), both ends all are provided with arrangement strip (6) around shell (51), arrangement strip (6) comprise arrangement board (61), spring (62), fixed block (63), sliding block (64) and slider (65), spring coupling is carried out through spring (62) and shell (51) in arrangement board (61), arrangement board (61) rear end face middle-end is provided with fixed block (63), sliding block (64) carry out sliding connection through slider (65) and shell (51).
2. The scanning scaffold for in situ hybridization of nucleic acid according to claim 1, wherein: the anti-slip strip is arranged on the top end face of the pressing plate (54), and the pressing plate (54) is arc-shaped and 3mm thick.
3. The scanning scaffold for in situ hybridization of nucleic acid according to claim 1, wherein: slide groove (4) are provided with two rows, one row slide groove (4) are located dog (2) front end, another row slide groove (4) are located dog (2) rear end to one row is provided with 7 slide groove (4), transparent plate (1) are controlled both ends middle-end and are all provided with the plastic block.
4. The scanning scaffold for in situ hybridization of nucleic acid according to claim 1, wherein: the angle of the top end face of the fixed block (63) is 5 degrees, the angle of the bottom end face of the sliding block (64) is 5 degrees, and the surfaces of the fixed block (63) and the sliding block (64) are smooth.
5. The scanning scaffold for in situ hybridization of nucleic acid according to claim 1, wherein: the rear end face of the tidying plate (61) is provided with two springs (62), one spring (62) is located on the left side of the rear end face of the tidying plate (61), the other spring (62) is located on the right side of the rear end face of the tidying plate (61), and the springs (62) are in a compressed state.
6. The scanning scaffold for in situ hybridization of nucleic acid according to claim 1, wherein: the middle part of the baffle (52) is hollowed, and the width of the baffle (52) is 4 mm.
7. The scanning scaffold for in situ hybridization of nucleic acid according to claim 1, wherein: the surface of the movable strip (56) is in the same horizontal position with the surface of the baffle (52), and the width of the movable strip (56) is 4 mm.
8. The scanning scaffold for in situ hybridization of nucleic acid according to claim 1, wherein: two grooves are arranged on the inner side of the shell (51), and the springs (62) are arranged in the grooves.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020772747.XU CN212741291U (en) | 2020-05-11 | 2020-05-11 | Nucleic acid in situ hybridization is with scanning support |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020772747.XU CN212741291U (en) | 2020-05-11 | 2020-05-11 | Nucleic acid in situ hybridization is with scanning support |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN212741291U true CN212741291U (en) | 2021-03-19 |
Family
ID=75004166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202020772747.XU Expired - Fee Related CN212741291U (en) | 2020-05-11 | 2020-05-11 | Nucleic acid in situ hybridization is with scanning support |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN212741291U (en) |
-
2020
- 2020-05-11 CN CN202020772747.XU patent/CN212741291U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210319 |