CN212680879U - A mixing arrangement for tablet production - Google Patents
A mixing arrangement for tablet production Download PDFInfo
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- CN212680879U CN212680879U CN202021235136.8U CN202021235136U CN212680879U CN 212680879 U CN212680879 U CN 212680879U CN 202021235136 U CN202021235136 U CN 202021235136U CN 212680879 U CN212680879 U CN 212680879U
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Abstract
The utility model provides a mixing device for tablet production, which comprises a shell, wherein a mechanical stirring device and a spiral stirring device are sequentially arranged in the shell from top to bottom; the mechanical stirring device comprises a stirring shell and a stirring mechanism, the stirring shell is fixed at the top of the shell, the stirring mechanism comprises a mechanical stirring shaft positioned in the stirring shell and a mechanical stirring motor in transmission connection with the top end of the mechanical stirring shaft, and stirring blades are arranged on the mechanical stirring shaft; the inner wall of the stirring shell is provided with a stirring rod, and the stirring blades and the stirring rod are respectively distributed on the inner wall of the mechanical stirring shaft and the inner wall of the stirring shell in a staggered manner in the vertical direction. Provides a good mixing foundation for stirring and mixing materials, so that the raw materials and the auxiliary materials of the tablet are mixed more uniformly, the mixing efficiency is improved, and the quality of finished products is finally improved.
Description
Technical Field
The utility model belongs to the technical field of pharmaceutical equipment, a mixing arrangement is related to, especially, relate to a mixing arrangement for tablet production.
Background
The pharmaceutical technology is characterized in that the pharmaceutical technology is a product for prevention, treatment and diagnosis, which is manufactured by comprehensively utilizing the principles and methods of science such as microbiology, chemistry, biochemistry, biotechnology, pharmacy and the like from organisms, biological tissues, cells, body fluids and the like by applying the research results such as microbiology, biology, medicine, biochemistry and the like, wherein the product comprises a tablet, and the tablet is a tablet prepared from medicines, pesticides and proper auxiliary materials through preparation technology.
The tablet is developed on the basis of pill use, and is a tablet or special-shaped tablet solid preparation formed by uniformly mixing a medicament and auxiliary materials and then pressing. It was used in the 40 s of the nineteenth century, and by the end of the 19 th century, the production and application of tablets have been rapidly developed with the advent and continued improvement of tabletting machinery. In recent decades, tablet production techniques and mechanical equipment have been developed, such as fluid granulation, direct whole powder compression, semi-film coating, new excipients, new processes, and linked production. The research and production of the traditional Chinese medicine tablets only begin in 50 years, and along with the comprehensive research of the aspects of chemistry, pharmacology, preparation and clinic of traditional Chinese medicines, the varieties and the number of the traditional Chinese medicine tablets are continuously increased, the process technology is gradually improved, and the quality of the tablets is gradually improved. The types of the traditional Chinese medicine tablets include common pressed tablets, sugar-coated tablets, micro-capsule tablets, buccal tablets, external tablets, effervescent tablets and the like. A set of process conditions suitable for the production of the traditional Chinese medicine tablets are gradually explored in the aspect of the production process of the tablets, for example, for the preparation of the tablets containing the fatty oil and the volatile oil, the experience of gradually accumulating how to improve the hardness, the disintegration, the tablet coating and the like of the traditional Chinese medicine tablets is improved, and the quality is continuously improved. In addition, studies on the dissolution rate and bioavailability of drugs in the Chinese medicinal tablet have been gradually conducted. In a word, the existing tablet has become one of the dosage forms with multiple varieties, large output, wide application, convenient use, storage and transportation and stable quality, and the tablet accounts for more than 1/3 in preparations collected by pharmacopoeias in China and many other countries, thus having wide application.
Compared with pills, the tablets have the following advantages: (1) generally, the dissolution rate and the bioavailability of the tablet are better than those of pills; (2) the dosage is accurate, and the content difference of the medicine in the tablet is small; (3) the quality is stable, the tablet is a dry solid, certain medicines which are easy to oxidize and deteriorate and easy to deliquesce can be protected by coating, and the influence of light, air, moisture and the like on the medicines is small; (4) convenient to take, carry and transport; (5) mechanized production, large output, low cost and easy reaching of sanitary standard.
The preparation of the tablet needs the common matching of the raw materials and the auxiliary materials to play the real role, and a raw material and auxiliary material mixing device is needed in the preparation process of the tablet.
CN210448908U discloses raw materials mixing arrangement is used in western medicine tablet production, including the compounding jar, the top movable mounting of compounding jar has the housing, the top fixed mounting of housing has the motor cabinet, the top fixed mounting of motor cabinet has the motor, the cavity has been seted up in the housing, the output shaft department fixed mounting of motor has the puddler that runs through the housing and extend to compounding jar inside, the inside fixed mounting of housing has the first motor that is located the cavity, the inside fixed mounting of housing has the axle bed that is located the cavity, the output shaft department fixed mounting of first motor has the axostylus axostyle with axle bed swing joint.
CN208320641U discloses mixing arrangement for tablet drug manufacturing, comprising a base plate, be fixed with the support column that the symmetry set up on the top surface of bottom plate, the side top that the support column is close to each other is connected with first crossbeam, it is connected with the mixing drum to rotate on the first crossbeam, be fixed with the ring gear on the side that the mixing drum is close to first crossbeam, be connected with the second crossbeam that is located first crossbeam below on the side of support column, install first motor on the side of second crossbeam, the output of first motor is connected with the drive gear who is connected with the ring gear meshing, the top surface center of mixing drum rotates and is connected with the (mixing) shaft, be connected with the stirring rod on the side of (mixing) shaft, the top outside sliding connection of (mixing) shaft has driven gear.
CN206304679U discloses a mixing device for manufacturing tablet coating powder, which comprises a mixing box, a stirring shaft, a helical blade, a stirring shaft driving mechanism, a piston shaft, a piston and a piston shaft driving mechanism, wherein the top of the mixing box is provided with a material inlet and an additive inlet; the inner wall of the mixing box is inclined and is cylindrical with a wide upper part and a narrow lower part; a plurality of convex edges with different sizes are arranged on the inner wall of the mixing box at equal intervals; the bottom end of the stirring shaft is vertically inserted into the mixing box, and the top end of the stirring shaft penetrates through the mixing box; the helical blades are fixed on the stirring shaft; the stirring shaft driving mechanism is arranged at the top of the mixing box and drives the stirring shaft to do rotary lifting motion; the top end of the piston shaft is vertically inserted into the mixing box and connected with the piston, and the bottom end of the piston shaft penetrates through the mixing box; the piston shaft driving mechanism is arranged at the bottom of the mixing box and drives the piston shaft to do lifting motion.
The existing raw and auxiliary material mixing device has the defects that the mixing effect is poor, namely, the raw and auxiliary materials cannot be fully mixed together, and the mixing device cannot control the quantity of the raw and auxiliary materials, so that the proportion of the quantity of the raw and auxiliary materials in a tablet is influenced.
SUMMERY OF THE UTILITY MODEL
Not enough to prior art exists, the utility model aims to provide a mixing arrangement for tablet production provides good mixed basis for the stirring compounding, makes the mixture of tablet raw materials and auxiliary material more even and improve mixing efficiency, finally improves finished product quality.
To achieve the purpose, the utility model adopts the following technical proposal:
the utility model provides a mixing arrangement for tablet production, mixing arrangement include the casing, the casing inside mechanical stirring device and spiral agitating unit have set gradually from top to bottom.
The mechanical stirring device comprises a stirring shell and a stirring mechanism, wherein the stirring shell is fixed at the top of the shell, the stirring mechanism comprises a mechanical stirring shaft positioned inside the stirring shell and a mechanical stirring motor in transmission connection with the top end of the mechanical stirring shaft, and the mechanical stirring shaft is provided with stirring blades.
The inner wall of stirring shell on be provided with two-layer at least stirring rod subassembly along vertical direction equidistance, the stirring rod subassembly with stirring vane crisscross the distribution in proper order in vertical direction.
The material carries out the first mixture in mechanical stirring device, and at the mechanical stirring in-process, through puddler and stirring vane's supplementary cooperation, the dead angle appears in having avoided mechanical stirring device, causes the waste of raw materials and auxiliary material, then carries out the secondary through spiral agitating unit and stirs the mixture, for stirring the compounding and providing good mixed basis, makes the mixture of tablet raw materials and auxiliary material more even and improve mixing efficiency, finally improves finished product quality.
As an optimal technical scheme, stirring shell be the back taper structure, the stirring shell bottom of back taper structure be provided with the discharge gate, the discharge gate just right spiral agitating unit.
As an optimized technical proposal of the utility model, the top of the stirring shell is provided with a feed inlet.
As an optimized technical scheme, the stirring rod subassembly include along the at least three stirring rod that stirring shell inner wall circumference equidistance set up.
As an optimized technical scheme of the utility model, the puddler that upper and lower adjacent two-layer puddler subassembly contained distributes on the horizontal plane of difference by dislocation.
As an optimized technical proposal of the utility model, the stirring blade comprises two stirring paddles which are symmetrically arranged at the two sides of the mechanical stirring shaft.
The number of the stirring blades is the same as that of the stirring rod assemblies.
As an optimal technical scheme of the utility model, the spiral agitating unit including transversely set up in spiral stirring shaft and the spiral agitator motor who is connected rather than the transmission under the mechanical stirring device.
And helical blades are axially arranged on the helical stirring shaft.
As an optimized technical solution of the present invention, the mixing device further includes a discharging chamber connected with the outer edge of the housing.
The unloading cavity is of an inverted cone structure.
As an optimized technical scheme of the utility model, the butt joint face department of casing and unloading chamber be provided with screening plant.
As an optimal technical scheme, the intracavity of unloading be provided with at least one baffle along the direction of unloading, the baffle will be unloaded the chamber and separate for two at least discharge passage of mutual independence.
Compared with the prior art, the beneficial effects of the utility model are that:
the material carries out the first mixture in mechanical stirring device, and at the mechanical stirring in-process, through puddler and stirring vane's supplementary cooperation, the dead angle appears in having avoided mechanical stirring device, causes the waste of raw materials and auxiliary material, then carries out the secondary through spiral agitating unit and stirs the mixture, for stirring the compounding and providing good mixed basis, makes the mixture of tablet raw materials and auxiliary material more even and improve mixing efficiency, finally improves finished product quality.
Drawings
Fig. 1 is a schematic structural diagram of a mixing device according to an embodiment of the present invention;
fig. 2 is a top view of the stirring shell according to the embodiment of the present invention.
Wherein, 1-shell; 2-a mechanical stirring device; 21-a housing; 22-mechanical stirring motor; 23-mechanical stirring shaft; 24-stirring blades; 241-a first stirring blade; 242-a second stirring blade; 25-a stir bar assembly; 251-a first stirring rod assembly; 252-a second agitator bar assembly; 3-a spiral stirring device; 31-a helical stirring shaft; 32-a helical stirring motor; 33-helical blades; 4-a screening device; 5-a discharge cavity; 51-a separator.
Detailed Description
It is to be understood that in the description of the present invention, the terms "central," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in the orientation or positional relationship indicated in the drawings for the purpose of convenience and simplicity of description, and are not intended to indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and are not to be construed as limiting the present invention. Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first," "second," etc. may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless otherwise specified.
It should be noted that, unless explicitly stated or limited otherwise, the terms "disposed," "connected" and "connected" in the description of the present invention are to be construed broadly, and may for example be fixedly connected, detachably connected or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
The technical solution of the present invention is further explained by the following embodiments with reference to the accompanying drawings.
In a specific embodiment, the utility model provides a mixing arrangement for tablet production, mixing arrangement as shown in figure 1, including casing 1, casing 1 is inside to have set gradually mechanical stirring device 2 and helical stirring device 3 from top to bottom.
The mechanical stirring device 2 comprises a stirring shell 21 and a stirring mechanism, wherein the stirring shell 21 is fixed on the top of the shell 1. Stirring shell 21 is the back taper structure, and the stirring shell 21 bottom of back taper structure is provided with the discharge gate, and the discharge gate is just to spiral agitating unit 3, and the top of stirring shell 21 is provided with the feed inlet. At least two layers of stirring rod assemblies 25 are arranged on the inner wall of the stirring shell 21 along the vertical direction at equal intervals, and each stirring rod assembly 25 comprises at least three stirring rods arranged along the circumferential direction at equal intervals on the inner wall of the stirring shell 21. The stirring rods contained in the two adjacent layers of stirring rod assemblies 25 are distributed in a staggered manner on different horizontal planes.
The stirring mechanism comprises a mechanical stirring shaft 23 positioned in the stirring shell 21 and a mechanical stirring motor in transmission connection with the top end of the mechanical stirring shaft 23, and stirring blades 24 are arranged on the mechanical stirring shaft 23. The stirring blade 24 includes two stirring paddles symmetrically disposed at both sides of the mechanical stirring shaft 23. The number of the stirring blades 24 is the same as that of the stirring rod assemblies 25, and the stirring rod assemblies 25 and the stirring blades 24 are sequentially distributed in a staggered manner in the vertical direction.
The spiral stirring device 3 comprises a spiral stirring shaft 31 transversely arranged right below the mechanical stirring device 2 and a spiral stirring motor 32 in transmission connection with the spiral stirring shaft 31, and a spiral blade 33 is arranged on the spiral stirring shaft 31 along the axial direction.
The mixing device also comprises a discharging cavity 5 butted with the outer edge of the shell 1, and the discharging cavity 5 is of an inverted cone structure. The abutting surface of the shell 1 and the discharging cavity 5 is provided with a screening device 4. At least one partition plate 51 is arranged in the discharging cavity 5 along the discharging direction, and the partition plate 51 divides the discharging cavity 5 into at least two mutually independent discharging channels.
Examples
The embodiment provides a mixing device for tablet production, which is shown in fig. 1 and comprises a shell 1, wherein a mechanical stirring device 2 and a spiral stirring device 3 are sequentially arranged inside the shell 1 from top to bottom.
The mechanical stirring device 2 comprises a stirring shell 21 and a stirring mechanism, wherein the stirring shell 21 is fixed on the top of the shell 1. Stirring shell 21 is the back taper structure, and the stirring shell 21 bottom of back taper structure is provided with the discharge gate, and the discharge gate is just to spiral agitating unit 3, and the top of stirring shell 21 is provided with the feed inlet. Two layers of stirring rod assemblies 25 are arranged on the inner wall of the stirring shell 21 along the vertical direction at equal intervals, the stirring rod assemblies are sequentially marked as a first stirring rod assembly 251 and a second stirring rod assembly 252 from top to bottom, the two layers of stirring rod assemblies 25 respectively comprise four stirring rods arranged along the inner wall of the stirring shell 21 along the circumferential direction at equal intervals, and the included angle between every two adjacent stirring rods of the same layer of stirring rod assembly 25 is 90 degrees (as shown in fig. 2, different filling patterns represent different stirring rod assemblies 25). The four agitator bars included in the first agitator assembly 251 are offset by 45 from the four agitator bars included in the second agitator assembly 252 in different horizontal planes (as shown in fig. 2, different fill patterns represent different agitator bar assemblies 25).
The stirring mechanism comprises a mechanical stirring shaft 23 positioned inside the stirring shell 21 and a mechanical stirring motor in transmission connection with the top end of the mechanical stirring shaft 23, two stirring blades 24 are arranged on the mechanical stirring shaft 23 along the axial direction at equal intervals, the stirring blades are sequentially marked as a first stirring blade 241 and a second stirring blade 242 from top to bottom, and the two stirring blades 24 respectively comprise two stirring paddles symmetrically arranged at two sides of the mechanical stirring shaft 23.
The first agitating bar assembly 251, the first agitating blade 241, the second agitating bar assembly 252, and the second agitating blade 242 are alternately arranged in this order.
The spiral stirring device 3 comprises a spiral stirring shaft 31 transversely arranged right below the mechanical stirring device 2 and a spiral stirring motor 32 in transmission connection with the spiral stirring shaft 31, and a spiral blade 33 is arranged on the spiral stirring shaft 31 along the axial direction.
The mixing device also comprises a discharging cavity 5 butted with the outer edge of the shell 1, and the discharging cavity 5 is of an inverted cone structure. The abutting surface of the shell 1 and the discharging cavity 5 is provided with a screening device 4. A partition plate 51 is arranged in the discharging cavity 5 along the discharging direction, and the partition plate 51 divides the discharging cavity 5 into two mutually independent discharging channels.
The applicant states that the above description is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and those skilled in the art should understand that any changes or substitutions easily conceivable by those skilled in the art within the technical scope of the present invention are within the protection scope and the disclosure scope of the present invention.
Claims (10)
1. A mixing device for tablet production is characterized by comprising a shell, wherein a mechanical stirring device and a spiral stirring device are sequentially arranged in the shell from top to bottom;
the mechanical stirring device comprises a stirring shell and a stirring mechanism, the stirring shell is fixed at the top of the shell, the stirring mechanism comprises a mechanical stirring shaft positioned in the stirring shell and a mechanical stirring motor in transmission connection with the top end of the mechanical stirring shaft, and stirring blades are arranged on the mechanical stirring shaft;
the inner wall of stirring shell on be provided with two-layer at least stirring rod subassembly along vertical direction equidistance, the stirring rod subassembly with stirring vane crisscross the distribution in proper order in vertical direction.
2. The mixing device of claim 1, wherein the stirring shell is of an inverted conical structure, a discharge hole is formed in the bottom of the inverted conical stirring shell, and the discharge hole is opposite to the spiral stirring device.
3. The mixing device of claim 2, wherein the top of the agitator housing is provided with a feed inlet.
4. The mixing device of claim 3, wherein said agitator bar assembly comprises at least three agitator bars equally spaced circumferentially along the inner wall of the agitator housing.
5. The mixing device according to claim 4, wherein the stirring rods of the two adjacent stirring rod assemblies are staggered on different horizontal planes.
6. The mixing device according to claim 5, wherein said stirring blade comprises two stirring paddles symmetrically disposed on both sides of the mechanical stirring shaft;
the number of the stirring blades is the same as that of the stirring rod assemblies.
7. The mixing device of claim 6, wherein the helical stirring device comprises a helical stirring shaft transversely arranged right below the mechanical stirring device and a helical stirring motor in transmission connection with the helical stirring shaft;
and helical blades are axially arranged on the helical stirring shaft.
8. The mixing device of claim 7, further comprising a discharge chamber interfacing with an outer edge of said housing;
the unloading cavity is of an inverted cone structure.
9. A mixing apparatus according to claim 8, wherein a screening means is provided at the interface of the housing with the discharge chamber.
10. The mixing device according to claim 9, wherein at least one partition is provided in the discharge chamber in the discharge direction, said partition dividing the discharge chamber into at least two discharge channels independent of each other.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021235136.8U CN212680879U (en) | 2020-06-29 | 2020-06-29 | A mixing arrangement for tablet production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021235136.8U CN212680879U (en) | 2020-06-29 | 2020-06-29 | A mixing arrangement for tablet production |
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| Publication Number | Publication Date |
|---|---|
| CN212680879U true CN212680879U (en) | 2021-03-12 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202021235136.8U Active CN212680879U (en) | 2020-06-29 | 2020-06-29 | A mixing arrangement for tablet production |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115493375A (en) * | 2022-09-30 | 2022-12-20 | 湖南省中医药研究院 | Formula granule production of pharmaceuticals is with shaping desiccator |
-
2020
- 2020-06-29 CN CN202021235136.8U patent/CN212680879U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115493375A (en) * | 2022-09-30 | 2022-12-20 | 湖南省中医药研究院 | Formula granule production of pharmaceuticals is with shaping desiccator |
| CN115493375B (en) * | 2022-09-30 | 2023-08-18 | 湖南省中医药研究院 | Forming dryer for producing formula granule medicines |
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