CN212576096U

CN212576096U - Mixing arrangement that biomacromolecule medicine concentration detected usefulness

Info

Publication number: CN212576096U
Application number: CN202020829084.0U
Authority: CN
Inventors: 孙梦雅
Original assignee: Shanghai Xinjier Biotechnology Co ltd
Current assignee: Shanghai Xinjier Biotechnology Co ltd
Priority date: 2020-05-19
Filing date: 2020-05-19
Publication date: 2021-02-23
Anticipated expiration: 2030-05-19

Abstract

The utility model discloses a mixing arrangement that biomacromolecule medicine concentration detection used, including mixing chamber, protective cover, protecting box, driving motor, filling tube and discharging pipe, protecting box fixed mounting is at the top of protective cover, and driving motor sets up the inside at the protecting box, and driving motor's output shaft has the pivot through the coupling joint, and the bottom of pivot extends to the inside of mixing chamber, and the surface of pivot is provided with the inside protection box that is located the mixing chamber. The utility model discloses a mutually supporting of vertical stirring fan blade and horizontal stirring fan blade can make the faster misce bene of the inside mixture of mixing chamber, and pulling pull ring makes the piston be located the right side of communicating pipe right, and the inside mixture of mixing chamber is flowed by sampling tube and communicating pipe this moment to the person of facilitating the use detects the contrast to the mixture that takes out different positions in mixing process, thereby knows whether misce bene of mixture.

Description

Mixing arrangement that biomacromolecule medicine concentration detected usefulness

Technical Field

The utility model relates to a mixing arrangement specifically is a mixing arrangement that biomacromolecule drug concentration detected usefulness.

Background

The biological macromolecular medicine is medicine prepared with microbe, cell and other biological material obtained through gene engineering, cell engineering, protein engineering, fermentation engineering and other biological technology and may be used in preventing, treating and diagnosing human diseases.

The concentration of biological macromolecule medicine can study the concentration change law of macromolecule medicine in the organism, clarify the pharmacokinetic parameter of medicine, monitor the medicine half-life, guide reasonable medicine, optimize dosing scheme etc, need mix multiple drug material before the concentration to biological macromolecule medicine detects, then draw the detection to the mixed liquid, consequently the homogeneity of medicine effective substance is very important among the mixing process, and current mixing arrangement is one-way stirring mostly when stirring, and one-way stirring will make the mixture reach evenly, probably need consume a large amount of time, thereby influence the efficiency that the medicine mixes. Therefore, we improve this and propose a mixing device for detecting the concentration of biomacromolecule drugs.

Disclosure of Invention

In order to solve the technical problem, the utility model provides a following technical scheme:

the utility model relates to a mixing device for detecting the concentration of biomacromolecule drugs, which comprises a mixing chamber, a protective cover, a protective box and a driving motor, the protective box is fixedly arranged at the top of the protective cover, the driving motor is arranged in the protective box, the output shaft of the driving motor is connected with a rotating shaft through a coupler, the bottom end of the rotating shaft extends into the mixing chamber, the outer surface of the rotating shaft is provided with a protective box positioned in the mixing chamber, the outer surface of the rotating shaft is fixedly provided with a driving wheel positioned in the protective box, the both ends of action wheel all mesh and are connected with from the driving wheel, two from the equal fixedly connected with connecting axle of the one end of keeping away from mutually of driving wheel, two the one end that the connecting axle was kept away from all passes the protection box and links to each other through the inner wall of sealed bearing and mixing chamber, two the equal fixedly connected with in surface of connecting axle is located the outside vertical stirring flabellum of protection box.

The right side of mixing chamber is provided with the sampling mechanism that a plurality of is used for the sample, sampling mechanism includes sampling tube, piston, connecting rod, pull ring and communicating pipe, the sampling tube inlays the right flank of establishing at the mixing chamber, the piston sets up the inside at the sampling tube, the right flank and the connecting rod fixed connection of piston, the right-hand member of connecting rod run through the sampling tube and with pull ring fixed connection, the fixed middle part that communicates in the sampling tube bottom of communicating pipe.

As an optimized technical scheme of the utility model, pass through bolted connection between mixing chamber and the protective cover, and be provided with seal ring between mixing chamber and the protective cover.

As an optimal technical scheme of the utility model, the right side at protection cover top is provided with the filling tube, and the top threaded connection of filling tube has sealed lid.

As a preferred technical scheme of the utility model, the fixed surface of pivot is connected with two horizontal stirring fan blades that the size is the same, two horizontal stirring fan blade is located the both sides of protection box respectively.

As a preferred technical scheme of the utility model, sampling mechanism still includes powerful spring, powerful spring's both ends respectively with the inner wall fixed connection on piston and sampling tube right side.

As a preferred technical scheme of the utility model, the bottom of mixing chamber is provided with the discharging pipe, and the junction of discharging pipe and mixing chamber is equipped with the valve, the fixed intercommunication in bottom of mixing chamber right flank has the switch, switch and driving motor electric connection, driving motor is external through the switch and has the power.

The utility model has the advantages that: this kind of mixing arrangement that biological macromolecule drug concentration detected usefulness, utilize two horizontal stirring fan blades to carry out horizontal stirring to the inside mixture of mixing chamber, utilize two vertical stirring fan blades to carry out vertical stirring to the inside mixture of mixing chamber, can make the faster misce bene of the inside mixture of mixing chamber through vertical stirring fan blade and horizontal stirring fan blade's mutually supporting, pulling the pull ring right makes the piston be located the right side communicating pipe, the inside mixture of mixing chamber is flowed by sampling tube and communicating pipe this moment, thereby the person of facilitating the use detects the contrast to the mixture that different positions were taken out in mixing process, thereby know whether misce bene of mixture.

Drawings

The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention. In the drawings:

FIG. 1 is a schematic structural diagram of a mixing device for detecting the concentration of a biomacromolecule drug according to the present invention;

FIG. 2 is a schematic front view of the mixing device for detecting the concentration of biomacromolecule drugs according to the present invention;

fig. 3 is an enlarged schematic structural diagram of a position a of the mixing device for detecting the concentration of the biomacromolecule drug of the present invention.

In the figure: 1. a mixing chamber; 2. a protective cover; 3. a protective box; 4. a drive motor; 5. a feed tube; 6. a rotating shaft; 7. a protective case; 8. a driving wheel; 9. a driven wheel; 10. a connecting shaft; 11. longitudinal stirring fan blades; 12. transverse stirring fan blades; 13. a sampling tube; 14. a piston; 15. a connecting rod; 16. a pull ring; 17. a strong spring; 18. a communicating pipe; 19. a switch; 20. and (4) discharging the pipe.

Detailed Description

The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are presented herein only to illustrate and explain the present invention, and not to limit the present invention.

Example (b): as shown in fig. 1, fig. 2 and fig. 3, the mixing device for detecting the concentration of biomacromolecule drugs of the present invention comprises a mixing chamber 1, a protective cover 2, a protective box 3 and a driving motor 4, wherein the protective box 3 is fixedly installed on the top of the protective cover 2, the driving motor 4 is arranged inside the protective box 3, an output shaft of the driving motor 4 is connected with a rotating shaft 6 through a coupling, the bottom end of the rotating shaft 6 extends into the mixing chamber 1, a protective box 7 located inside the mixing chamber 1 is arranged on the outer surface of the rotating shaft 6, a driving wheel 8 located inside the protective box 7 is fixedly installed on the outer surface of the rotating shaft 6, both ends of the driving wheel 8 are engaged with driven wheels 9, both ends of the two driven wheels 9 far away from each other are fixedly connected with a connecting shaft 10, both ends of the two connecting shafts 10 far away from each other pass through the protective box, the outer surfaces of the two connecting shafts 10 are fixedly connected with longitudinal stirring fan blades 11 outside the protective box 7, the type of the driving motor 4 is a 5IK120RGN-CF type driving motor, and sealing bearings are arranged at the connecting positions of the protective box 7, the connecting shafts 10 and the rotating shaft 6.

The right side of the mixing chamber 1 is provided with a plurality of sampling mechanisms for sampling, each sampling mechanism comprises a sampling tube 13, a piston 14, a connecting rod 15, a pull ring 16 and a communicating pipe 18, the sampling tube 13 is embedded on the right side surface of the mixing chamber 1, the piston 14 is arranged inside the sampling tube 13, the right side surface of the piston 14 is fixedly connected with the connecting rod 15, the right end of the connecting rod 15 penetrates through the sampling tube 13 and is fixedly connected with the pull ring 16, the communicating pipe 18 is fixedly communicated with the middle part of the bottom end of the sampling tube 13, the mixture in the mixing chamber 1 can be mixed uniformly and quickly by the mutual matching of the longitudinal stirring fan blades 11 and the transverse stirring fan blades 12, the piston 14 is positioned at the right side of the communicating pipe 18 by pulling the pull ring 16 rightwards, the mixture in the mixing chamber 1 flows out from the sampling pipe 13 and the communicating pipe 18, so that a user can sample and detect conveniently in the mixing process, thereby facilitating the user to know the mixing uniformity of the mixture in the mixing chamber 1 more clearly.

Wherein, pass through bolted connection between mixing chamber 1 and the protective cover 2, and be provided with seal ring between mixing chamber 1 and the protective cover 2, seal ring adopts rubber to make, can increase the leakproofness of mixing chamber 1 and protective cover 2 junction.

Wherein, the right side at protective cover 2 top is provided with filling tube 5, and the top end threaded connection of filling tube 5 has sealed lid, can be to 1 inside corresponding medicine of adding of mixing chamber through filling tube 5, and sealed lid can increase mixing chamber 1's leakproofness to prevent that the in-process impurity of mixing from getting into in the mixing chamber 1.

Wherein, the outer fixed surface of pivot 6 is connected with two horizontal stirring fan blades 12 that the size is the same, and two horizontal stirring fan blades 12 are located the both sides of protection box 7 respectively, utilize two horizontal stirring fan blades 12 to carry out horizontal stirring to the mixture of mixing chamber 1 inside, utilize two vertical stirring fan blades 11 to carry out vertical stirring to the mixture of mixing chamber 1 inside, can make the faster misce bene of the mixture of mixing chamber 1 inside through mutually supporting of vertical stirring fan blade 11 and horizontal stirring fan blade 12.

Wherein, the sampling mechanism still includes powerful spring 17, powerful spring 17's both ends respectively with inner wall fixed connection on piston 14 and sampling tube 13 right side, powerful spring 17 has very strong elasticity, can realize the shutoff to sampling tube 13 to prevent that the mixture from taking place to leak.

Wherein, the bottom of mixing chamber 1 is provided with discharging pipe 20, and discharging pipe 20 is equipped with the valve with the junction of mixing chamber 1, and the fixed intercommunication in bottom of 1 right flank of mixing chamber has switch 19, switch 19 and driving motor 4 electric connection, and driving motor 4 is external through switch 19 to have the power, can control opening of driving motor 4 through switch 19 and stop.

When the device works, firstly, the sealing cover at the top of the feeding pipe 5 is unscrewed, then a proper amount of medicine is added into the mixing chamber 1 through the feeding pipe 5, then the sealing cover is screwed down, an external power supply of the device is connected, then the switch 19 is pressed to enable the driving motor 4 to work in a power-on mode, at the moment, the driving motor 4 drives the rotating shaft 6 and the driving wheel 8 to rotate, the two transverse stirring fan blades 12 are driven to rotate through the rotating shaft 6, thereby transversely stirring the mixture in the mixing chamber 1, the two driven wheels 9 and the two connecting shafts 10 are driven to rotate through the driving wheel 8, the two longitudinal stirring fan blades 11 are driven to rotate through the rotation of the two connecting shafts 10, the mixture in the mixing chamber 1 is longitudinally stirred by the two longitudinal stirring fan blades 11, the mixture in the mixing chamber 1 can be uniformly mixed more quickly through the mutual matching of the longitudinal, pulling the pull ring 16 right and making piston 14 move to the right side of communicating pipe 18, the inside mixture of mixing chamber 1 flows out by sampling tube 13 and communicating pipe 18 this moment, then loosen pull ring 16, strong spring 17's effort promotes piston 14 and removes left this moment, thereby prevent that the inside mixture of mixing chamber 1 from flowing out, detect the contrast to the mixture that the different positions were taken out, thereby know whether the mixture misce bene, wait to cut off the external power supply of the device after the completion of mixing, then open the valve on the discharging pipe 20, it can to draw forth the mixture.

In the description of the present invention, it should be noted that the terms "vertical", "upper", "lower", "horizontal", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and thus should not be construed as limiting the present invention.

In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described in the foregoing embodiments, or equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The utility model provides a mixing arrangement that biological macromolecule medicine concentration detection used, includes mixing chamber (1), protective cover (2), protective housing (3) and driving motor (4), its characterized in that, protective housing (3) fixed mounting is at the top of protective cover (2), driving motor (4) set up the inside at protective housing (3), driving motor's (4) output shaft has pivot (6) through the coupling joint, the bottom of pivot (6) extends to the inside of mixing chamber (1), the surface of pivot (6) is provided with the protection box (7) that are located mixing chamber (1) inside, the surface fixed mounting of pivot (6) has action wheel (8) that are located protection box (7) inside, the both ends of action wheel (8) all mesh and are connected with from driving wheel (9), two the equal fixedly connected with connecting axle (10) of one end of keeping away from driving wheel (9) mutually, one ends, far away from the two connecting shafts (10), of the two connecting shafts penetrate through the protective box (7) and are connected with the inner wall of the mixing chamber (1) through sealed bearings, and longitudinal stirring blades (11) located outside the protective box (7) are fixedly connected to the outer surfaces of the two connecting shafts (10);

the right side of mixing chamber (1) is provided with the sampling mechanism that a plurality of was used for the sample, sampling mechanism includes sampling tube (13), piston (14), connecting rod (15), pull ring (16) and communicating pipe (18), sampling tube (13) are inlayed and are established the right flank in mixing chamber (1), piston (14) set up the inside at sampling tube (13), the right flank and connecting rod (15) fixed connection of piston (14), the right-hand member of connecting rod (15) run through sampling tube (13) and with pull ring (16) fixed connection, communicating pipe (18) fixed intercommunication is at the middle part of sampling tube (13) bottom.

2. The mixing device for detecting the concentration of biomacromolecule drugs according to claim 1, wherein the mixing chamber (1) and the protecting cover (2) are connected by a bolt, and a sealing gasket is arranged between the mixing chamber (1) and the protecting cover (2).

3. The mixing device for detecting the concentration of biomacromolecule drugs according to claim 1, wherein a feeding tube (5) is disposed at the right side of the top of the protective cover (2), and a sealing cover is screwed on the top end of the feeding tube (5).

4. The mixing device for detecting the concentration of biomacromolecule drugs according to claim 1, wherein two transverse stirring blades (12) with the same size are fixedly connected to the outer surface of the rotating shaft (6), and the two transverse stirring blades (12) are respectively positioned at two sides of the protection box (7).

5. The mixing device for detecting the concentration of biomacromolecule drugs according to claim 1, wherein the sampling mechanism further comprises a strong spring (17), and two ends of the strong spring (17) are respectively fixedly connected with the piston (14) and the inner wall of the right side of the sampling tube (13).

6. The mixing device for detecting the concentration of the biomacromolecule drug according to claim 1, wherein a discharge pipe (20) is arranged at the bottom of the mixing chamber (1), a valve is arranged at the joint of the discharge pipe (20) and the mixing chamber (1), a switch (19) is fixedly communicated with the bottom of the right side surface of the mixing chamber (1), the switch (19) is electrically connected with the driving motor (4), and the driving motor (4) is externally connected with a power supply through the switch (19).