CN212466737U - Stem cell feedback device - Google Patents

Stem cell feedback device Download PDF

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Publication number
CN212466737U
CN212466737U CN202021153341.XU CN202021153341U CN212466737U CN 212466737 U CN212466737 U CN 212466737U CN 202021153341 U CN202021153341 U CN 202021153341U CN 212466737 U CN212466737 U CN 212466737U
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CN
China
Prior art keywords
bag
transfusion
cleaning
tube
stem cell
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Expired - Fee Related
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CN202021153341.XU
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Chinese (zh)
Inventor
武坤
李轶勋
马晓波
李林燕
罗珊
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First Affiliated Hospital of Kunming Medical University
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First Affiliated Hospital of Kunming Medical University
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Priority to CN202021153341.XU priority Critical patent/CN212466737U/en
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Abstract

The utility model discloses a stem cell feedback device and a use method, in particular to the technical field of medical instruments. The utility model provides a stem cell feedback device and a use method, which is suitable for a cleaning bag, a blood transfusion bag, a transfusion pipeline, a transfusion rod and an infrared remote control through design, wherein the cleaning bag is a transfusion bag filled with physiological saline; the transfusion bag is a transfusion bag provided with cryopreserved stem cells, when patient stem cells are transfused, after the cryopreserved stem cells in the transfusion bag are transfused, a transfusion tube does not need to be pulled out to replace a cleaning pipeline, the inner wall of the transfusion bag can be washed by moving the three-way valve to communicate the double-purpose tube and the cleaning tube, after the washing is finished, the three-way valve is moved to communicate the double-purpose tube and the transfusion tube, and the washed liquid can be continuously input. Namely, during flushing and transfusion, the pipeline does not need to be plugged and pulled, thereby reducing the contact probability of external germs and reducing the treatment risk of patients.

Description

Stem cell feedback device
Technical Field
The utility model relates to the technical field of medical equipment, concretely relates to stem cell feedback device and application method thereof.
Background
Stem cells refer to cells that have not been differentiated, are present in early embryonic, bone marrow, umbilical cord, placenta, and partial adult cells, and can be cultured into human tissues and organs such as muscle, bone, and nerve. Scientists believe that tissues and organs cultured using stem cells are of great importance in the treatment of cancer and other various malignant diseases, and will bring hopes to patients with diabetes, alzheimer, parkinson and spinal cord injuries.
The collection and preservation of stem cells are carried out by carrying out large-dose chemotherapy and granulocyte colony-stimulating factor (G-CSF) combined mobilization on a patient, then peripheral blood stem cells are obtained by a COCOBESPpectra blood cell separator, or (and) the bone marrow of the patient in the remission stage is collected, the volume of the bone marrow is concentrated, then 10 percent of dimethyl sulfoxide (DMSO) antifreeze solution is added, the mixture is cooled to-80 ℃ by a program-controlled cooling machine, and then the mixture is placed in 196C liquid nitrogen for freezing and preservation for later use. The thawing and returning of the hematopoietic stem cells can be carried out after a certain time interval after the pretreatment.
The problems existing at present are as follows:
1. in order to maintain the activity of stem cells, the stem cell transfusion therapy adopts multiple transfusion bags for transfusion. After a bag of stem cell solution is transfused, the plug of the infusion tube needs to be pulled out, a normal saline washing bottle is connected, and stem cells remained on the wall of the bag are washed and injected into a patient. The infusion tube is pulled out of the stem cell solution bag and inserted into the infusion tube for many times, so that the possibility of bacterial infection is increased undoubtedly, and the treatment risk of patients is increased.
2. Along with the reduction of liquid in the bag, the infusion speed cannot be controlled due to the height fixation of the infusion tube, so that the flow rate of the residual stem cell solution is low, the activity of stem cells in the bag is easy to reduce for a long time, and the treatment effect is influenced.
SUMMERY OF THE UTILITY MODEL
To the above-mentioned problem that prior art exists, the utility model provides a stem cell feedback device and application method thereof washs bag, transfusion bag, infusion pipeline, transfusion rod, infrared remote control through the design, has solved above-mentioned problem.
In order to realize the technical purpose, the technical effect is achieved, the utility model discloses a realize through following technical scheme:
a stem cell reinfusion device comprises a cleaning bag, a blood transfusion bag, a transfusion pipeline, a transfusion rod and an infrared remote control, wherein the cleaning bag is the blood transfusion bag filled with physiological saline; the blood transfusion bag is filled with cryopreserved stem cells, and the bottom end of the blood transfusion bag is provided with a liquid outlet interface and a liquid supplementing interface; the infusion tube is composed of a cleaning tube, a dual-purpose tube and an infusion tube which are connected with a three-way valve; a cleaning tube is inserted into the bottom end of the blood transfusion bag through an interface, and a dual-purpose tube is inserted into a liquid outlet interface of the blood transfusion bag; through integrative pipeline, when infusing for patient's stem cell, the cryopreserved stem cell in the blood transfusion bag is lost the back, need not to pull out the transfer line and replace the washing pipeline, transfers three-way valve intercommunication double-purpose pipe and scavenge pipe and can wash the inner wall of blood transfusion bag. After the flushing is finished, the three-way valve is transferred to communicate the dual-purpose pipe and the infusion pipe, and the flushed liquid can be continuously input. A hydraulic push rod is arranged on the transfusion rod, an infrared receiving module is arranged in the hydraulic push rod, and the hydraulic push rod is controlled by infrared remote control; the left side and the right side of the inner rod of the hydraulic push rod are respectively provided with a hook, the left side hook is hung with a cleaning bag, the right side hook is hung with a blood transfusion bag, the left side hook is 300-500mm higher than the right side hook, so that the two bag bodies are ensured to have enough space, the flushing bag has enough pressure to flush flushing fluid into the blood transfusion bag, the infusion rod can be adjusted to a higher height during communication, and the flow speed of the fluid during the input of stem cells can be ensured to be rapid.
As another preferred scheme, the cleaning bag has a volume of 500ML, a hanging opening is formed in the upper end of the cleaning bag, and volume scales are arranged on the outer portion of the cleaning bag.
As another preferred scheme, the knob at the top end of the three-way valve is a cross knob, and the cross knob is communicated with a communicating cavity channel of the valve core control valve.
As another preferred scheme, the transfusion tube is connected with a Murphy's dropper and a speed regulating valve, and the far end of the transfusion tube is provided with a connector which can be connected with a transfusion needle tube.
As another preferred scheme, a tip plug is arranged at one end of the cleaning pipe and one end of the double-purpose pipe.
As another preferred scheme, the cleaning pipe and the double-purpose pipe are sleeved with pipeline clamps, and the pipeline channel can be temporarily closed.
As another preferred scheme, a servo motor is arranged inside the hydraulic push rod base, a remote receiving module is arranged on the servo motor in the hydraulic push rod, the servo motor can be controlled to drive the hydraulic push rod to stretch, and the hydraulic push rod is inserted into a power socket through a power line to supply power.
As another preferred scheme, the hydraulic push rod is a 24V small lifting rod, and the stroke is 800 mm.
As another preferred scheme, an infrared emission module is arranged in the infrared remote control, the tail end of the infrared remote control is connected with a connecting wire, the connecting wire is an elastic contraction wire, the connecting wire is connected to a buckle, the buckle is an annular buckle and can be opened towards two sides, after the connecting wire is folded, the connecting buckle can be buckled together through the buckling buckles on the two sides of the front end, the remote control can be fixed on a handrail of a hospital bed, a key and an indicator light are arranged on the remote control, an upper direction key and a lower direction key and an on-off key are arranged on the key, and the.
The hydraulic push rod and the infrared remote control are conventional choices in the prior art, and can be obtained by conventional means, and the working principle of the hydraulic push rod and the infrared remote control can be understood by persons skilled in the relevant technical field.
The utility model discloses beneficial effect:
the utility model relates to a stem cell feedback device:
1. through the pipeline of integration through the design, when infusing for patient's stem cell, the cryopreserved stem cell in the blood transfusion bag transfuses the back, need not extract the transfer line and replace the washing pipeline, transfers three-way valve intercommunication double-purpose pipe and scavenge pipe and can wash the blood transfusion bag inner wall, washes and finishes, transfers three-way valve intercommunication double-purpose pipe, transfer line, can continue the input with the liquid after washing. Namely, during flushing and transfusion, the pipeline does not need to be plugged and pulled, thereby reducing the contact probability of external germs and reducing the treatment risk of patients.
2. Through designing electronic transfusion rod, transfusion rod passes through infrared remote controller control, and remote control stores pylon height, change transfusion bag that can be convenient, simultaneously, along with the process of stem cell infusion, compare current transfusion rod, can progressively rise transfusion rod, let the blood transfusion bag be in higher position, improve the speed of infusion. The situation that the activity of stem cells in the bag is reduced and the treatment effect is influenced due to long infusion time is prevented.
Of course, it is not necessary for any product to achieve all of the above-described advantages simultaneously in practicing the invention.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a stem cell reinfusion device according to the present invention;
FIG. 2 is a schematic structural view of the cleaning bag of the present invention;
fig. 3 is a schematic structural view of the blood transfusion bag of the present invention;
FIG. 4 is a schematic structural view of the infusion pipeline of the present invention;
in the drawings, the components represented by the respective reference numerals are listed below:
1-cleaning bag, 101-bag opening, 102-scale, 103-hanging opening, 2-transfusion bag, 3-transfusion pipeline, 301-cleaning pipe, 302-double-purpose pipe 303-transfusion pipe, 304-three-way valve, 305-pipeline clamp, 306-speed regulating valve, 307-interface, 308-Murphy's dropper, 4-transfusion rod, 401-hydraulic push rod, 402-outer rod, 403-inner rod, 404-base, 405-universal wheel, 406-power line, 407-hook, 5-infrared remote control, 501-key, 502-prompting lamp, 503-fixing line and 504-buckle.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.
As shown in fig. 1-4
A stem cell transfusion device comprises a cleaning bag 1, a blood transfusion bag 2, a transfusion pipeline 3, a transfusion rod 4 and an infrared remote control 5, wherein the cleaning bag 1 is a blood transfusion bag filled with physiological saline;
the blood transfusion bag 2 is a blood transfusion bag filled with cryopreserved stem cells, and the bottom end of the blood transfusion bag is provided with a liquid outlet port 201 and a liquid supplementing port 202;
the infusion pipeline 3 is composed of a cleaning pipe 301, a double-purpose pipe 302 and an infusion pipe 303 which are connected with a three-way valve 304;
a cleaning tube 301 is inserted into the bottom end of the blood transfusion bag 2 through a port, and a dual-purpose tube 302 is inserted into the liquid outlet port 201 of the blood transfusion bag 2;
a hydraulic push rod 401 is arranged on the transfusion rod 4, an infrared receiving module is arranged in the hydraulic push rod, and the hydraulic push rod is controlled by an infrared remote control 5; the left side and the right side of an inner rod 403 of the hydraulic push rod 401 are respectively provided with a hook 403, the left side hook is hung with a cleaning bag 1, the right side hook is hung with a blood transfusion bag, and the height of the left side hook is 300-500mm higher than that of the right side hook.
As another preferred scheme, the cleaning bag 1 has a volume of 500ML, a hanging opening 103 is arranged at the upper end of the cleaning bag 1, and volume scales 102 are arranged outside the cleaning bag.
As another preferable scheme, the pipe diameter of the cleaning pipe 301 is 1.5-2 times of the pipe diameter of the dual-purpose pipe 302.
As another preferable scheme, the knob at the top end of the three-way valve 403 is a cross knob, and the cross knob is communicated with a communicating cavity of the valve core control valve.
As another preferable scheme, the infusion tube 303 is connected with a murphy dropper 308, a speed regulating valve 306, and a port 307 is arranged at the distal end, and the port 307 can be connected with an infusion needle tube.
As another preferable scheme, a tip plug 309 is arranged at one end of the cleaning tube 301 and the double-purpose tube 302.
As another preferable scheme, a servo motor is arranged inside the base of the hydraulic push rod 401, a remote receiving module is arranged on the servo motor in the hydraulic push rod, the servo motor can be controlled to drive the hydraulic push rod 401 to extend and retract, and the hydraulic push rod 401 is inserted into a power socket through a power line 406 to supply power.
As another preferred scheme, the hydraulic push rod is a 24V small lifting rod, and the stroke is 600 mm. As another preferred scheme, an infrared emission module is arranged in the infrared remote control 5, the tail end of the infrared remote control is connected with a connecting wire 503, the connecting wire 503 is an elastic contraction wire, the connecting wire is connected to a buckle 504, the buckle is an annular buckle and can be opened towards two sides, after the buckle is closed, the connecting wire can be buckled together through a closing buckle 505 on two sides of the front end, the remote control can be fixed on a handrail of a hospital bed, a key and an indicator light are arranged on the remote control, an upper direction key and a lower direction key and an on-off key are arranged on the key, and the indicator. The hydraulic push rod and the infrared remote control are conventional choices in the prior art, and can be obtained by conventional means, and the working principle of the hydraulic push rod and the infrared remote control can be understood by persons skilled in the relevant technical field.
The technical solution of the present invention is described below with reference to the following specific embodiments:
example 1
A stem cell transfusion device comprises a cleaning bag 1, a blood transfusion bag 2, a transfusion pipeline 3, a transfusion rod 4 and an infrared remote control 5, wherein the cleaning bag 1 is a blood transfusion bag filled with physiological saline; the blood transfusion bag 2 is a blood transfusion bag filled with cryopreserved stem cells, and the bottom end of the blood transfusion bag is provided with a liquid outlet port 201 and a liquid supplementing port 202; the infusion pipeline 3 is composed of a cleaning pipe 301, a double-purpose pipe 302 and an infusion pipe 303 which are connected with a three-way valve 304; a cleaning tube 301 is inserted into the bottom end of the blood transfusion bag 2 through a port, and a dual-purpose tube 302 is inserted into the liquid outlet port 201 of the blood transfusion bag 2; a hydraulic push rod 401 is arranged on the transfusion rod 4, an infrared receiving module is arranged in the hydraulic push rod, and the hydraulic push rod is controlled by an infrared remote control 5; the left side and the right side of an inner rod 403 of the hydraulic push rod 401 are respectively provided with a hook 403, the left side hook is hung with a cleaning bag 1, the right side hook is hung with a blood transfusion bag, and the height of the left side hook is 300-500mm higher than that of the right side hook.
Example 2
Based on example 1, a stem cell reinfusion device is used for the reinfusion of cryopreserved stem cells of a patient. In specific implementation, the infrared switch 5 is pressed, the infusion rod is lowered to the lowest height position, the frozen blood transfusion bag filled with stem cells is taken out from the constant-temperature water bath tank, the infusion tube is inserted into the bag 6, the infusion needle tube is connected into the connector, the blood transfusion bag is hung on the right hook, and the flushing tube is connected into the cleaning bag filled with physiological saline. Adjust the transfusion pole through infrared switch, let wash the bag, the blood transfusion bag arrives the high position, wash the bag and hang on the left side couple, open the three-way valve, open the governing valve, after discharging into the air of transfer line, can be patient's venipuncture, after the blood transfusion bag of the first generation of transfusions, adjust the three-way valve, intercommunication wash tube and double-purpose pipe, the flush fluid in the wash bag is washed into the blood transfusion bag, treat to wash full back, adjust the three-way valve, the bag after will washing has the liquid of stem cell to pour into patient internal, can repeat above step and carry out many bags of stem cell input for patient. When the patient stem cells are transfused, after the cryopreserved stem cells in the blood transfusion bag 2 are completely transfused, the infusion tube 302 is not pulled out to replace a cleaning pipeline, and the inner wall of the blood transfusion bag can be washed by transferring the three-way valve 304 to communicate the double-purpose tube 302 with the cleaning tube 301. After the flushing is finished, the three-way valve 304 is transferred to communicate the double-purpose pipe 302 and the infusion pipe 301, and then the flushed liquid can be continuously input.
In the description herein, references to the description of "one embodiment," "an example," "a specific example," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and its practical applications, to thereby enable others skilled in the art to best understand the invention for and utilize the invention. The present invention is limited only by the claims and their full scope and equivalents.

Claims (8)

1. A stem cell reinfusion device, comprising: the device comprises a cleaning bag, a blood transfusion bag, a transfusion pipeline, a transfusion rod and an infrared remote controller, wherein the cleaning bag is a transfusion bag filled with physiological saline;
the blood transfusion bag is filled with cryopreserved stem cells, and the bottom end of the blood transfusion bag is provided with a liquid outlet interface and a liquid supplementing interface;
the infusion tube is composed of a cleaning tube, a double-way tube and an infusion tube which are connected with a three-way valve;
a cleaning tube is inserted into the bottom end of the blood transfusion bag through a port, and a dual-purpose tube is inserted into a liquid outlet port of the transfusion bag;
a hydraulic push rod is arranged on the transfusion rod, an infrared receiving module is arranged in the hydraulic push rod, and the hydraulic push rod is controlled by infrared remote control; the left side and the right side of the inner rod of the hydraulic push rod are respectively provided with a hook, the left side hook is hung with a cleaning bag, the right side hook is hung with a blood transfusion bag, and the height of the left side hook is 300-500mm higher than that of the right side hook.
2. The stem cell reinfusion device of claim 1, wherein: the cleaning bag volume is 500ML, and the cleaning belt upper end is equipped with hangs the mouth, and the outside is equipped with the volume scale.
3. The stem cell reinfusion device of claim 1, wherein: the knob at the top end of the three-way valve is a cross knob, and the cross knob is communicated with a communicating cavity channel of the valve core control valve.
4. The stem cell reinfusion device of claim 1, wherein: the transfusion tube is connected with a Murphy dropper, a speed regulating valve and a connector arranged at the far end, and the connector can be connected with a transfusion needle tube.
5. The stem cell reinfusion device of claim 1, wherein: and one end of the cleaning pipe and one end of the double-pass pipe are provided with tip plugs.
6. The stem cell reinfusion device of claim 1, wherein: the hydraulic push rod base is internally provided with a servo motor, a remote receiving module is arranged on a servo motor in the hydraulic push rod, the servo motor can be controlled to drive the hydraulic push rod to stretch, and the hydraulic push rod is inserted into a power socket through a power line to supply power.
7. The stem cell reinfusion device according to any of the claims 1 or 6, wherein: the type of the hydraulic push rod is a 24V small-sized lifting rod, and the stroke is 800 mm.
8. The stem cell reinfusion device of claim 1, wherein: the remote control device is characterized in that an infrared emission module is arranged in the infrared remote control, the tail end of the infrared remote control device is connected with a connecting wire, the connecting wire is an elastic contraction wire, the connecting wire is connected to a buckle, the buckle is an annular buckle and can be opened towards two sides, after the buckle is closed, the connecting wire can be buckled together through the buckling of the two sides of the front end, the remote control device can be fixed on a sickbed handrail, a key and an indicator lamp are arranged on the remote control device, an upper direction key and a lower direction key and an on-off key are.
CN202021153341.XU 2020-06-20 2020-06-20 Stem cell feedback device Expired - Fee Related CN212466737U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202021153341.XU CN212466737U (en) 2020-06-20 2020-06-20 Stem cell feedback device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202021153341.XU CN212466737U (en) 2020-06-20 2020-06-20 Stem cell feedback device

Publications (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111729150A (en) * 2020-06-20 2020-10-02 昆明医科大学第一附属医院 Stem cell feedback device and using method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111729150A (en) * 2020-06-20 2020-10-02 昆明医科大学第一附属医院 Stem cell feedback device and using method

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20210205

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CF01 Termination of patent right due to non-payment of annual fee