CN212439710U

CN212439710U - Cranial nerve regulator

Info

Publication number: CN212439710U
Application number: CN202020730485.0U
Authority: CN
Inventors: 胥红来; 寇宇畅; 洪宇祥; 黄肖山; 刘涛; 窦莲莲; 李旭
Original assignee: Neuracle Technology Changzhou Co ltd
Current assignee: Neuracle Technology Changzhou Co ltd
Priority date: 2020-05-07
Filing date: 2020-05-07
Publication date: 2021-02-02
Anticipated expiration: 2030-05-07

Abstract

The disclosure relates to the technical field of electronic medical treatment, and provides a cranial nerve regulator which comprises an implant body and an extracorporeal machine. The implant includes an implant body and at least one electrode set. The electrode group is electrically connected with the implant body through the electrode wire. The implant body includes an energy receiver and an implant host. The extracorporeal machine comprises an extracorporeal main machine and an energy transmitter. The energy emitter is electrically connected with the external machine host through a connecting wire. The energy receiver is adapted to be wirelessly coupled with the energy transmitter to obtain electric energy for powering the implant host from the external machine, and the implant host is adapted to be wirelessly communicatively connected with the external machine. When the implant body is used, the implant body main body part is implanted under the cortex of the back part of the ear of a user, the electrode is penetrated and led to a lesion part under the skin, the electrode wire is short, and the receiving of interference signals is reduced. The electrode is a cortical electrode, and the electrode is arranged between the dura mater and the bone, so that brain tissue cannot be damaged. The power supply is carried out through magnetic coupling, and the signal transmission and the signal acquisition are not influenced.

Description

Cranial nerve regulator

Technical Field

The utility model relates to an electronic medical treatment technical field particularly, relates to a cranial nerve regulator.

Background

The implanted cranial nerve regulator is used for collecting and treating cranial nerve signals and is widely applied to the treatment of chronic diseases such as Parkinson, dystonia, essential tremor, epilepsy and the like. In the prior art, as shown in fig. 1, an implantable cranial nerve regulator generally includes an implant 1 and an electrode 2. The implant 1 is typically placed subcutaneously in the chest wall and the electrodes 2 are implanted in the brain. The implant 1 is connected with the electrode 2 through a subcutaneous lead 3, and the electrode 2 is used for collecting physiological electric signals and outputting stimulation electric signals at the target nucleus 4.

However, the existing cranial nerve modulation device implanted in the chest wall/abdominal wall has the following problems:

1. skin ulceration infection by implants or connecting wires: especially in elderly or patients with thin skin and poor elasticity. Furthermore, once infection has occurred, debridement, re-deep embedding, antibiotic application are often ineffective and only the implant can be removed.

2. The electrode wire is easy to break: most of the breakage occurs behind the ear, especially at the interface of the intracranial electrode and the extension wire.

3. The connecting wires introduce interference signals: for the feedback type implanted cranial nerve modulation device, a cranial nerve signal needs to be collected, and more interference signals are introduced by the overlong lead.

4. Short service life: the built-in battery is used, the service life is short, and the data transmission with large data volume and long time is not supported.

SUMMERY OF THE UTILITY MODEL

The embodiment of the utility model provides a cranial nerve regulator, which is suitable for being directly implanted into cerebral cortex and is wirelessly powered to solve the above-mentioned partial or whole technical problems in the prior art.

The brain nerve regulator provided by the embodiment of the utility model can comprise an implant and an external machine communicated with the implant in a wireless communication mode;

the implant comprises an implant body and at least one electrode group, wherein the implant body is suitable for being implanted into the cortex of the back of the ear of a user, the electrode group is suitable for being implanted into the cerebral cortex of any target part of the user, the electrode group is electrically connected with the implant body through an electrode wire, and the implant body comprises an energy receiver and an implant host;

the extracorporeal machine comprises an extracorporeal machine main machine and an energy emitter, and the energy emitter is electrically connected with the extracorporeal machine main machine through a connecting wire;

wherein the energy receiver is adapted to be wirelessly coupled with the energy transmitter to obtain electrical energy from the extracorporeal machine to power the implant host.

Wherein, the electrode group can be including the stimulation electrode that is used for exporting stimulation signal and the collection electrode that is used for gathering the physiological signal of telecommunication, the utility model discloses do not limit the quantity of electrode, can set up wantonly according to the demand.

In an embodiment of the present invention, the implant host comprises the following circuit modules:

the implant receiving power supply unit is electrically connected with the energy receiver to convert the energy received by the energy receiver from the energy transmitter into power supply voltage suitable for the implant host;

a stimulation unit electrically connected with the stimulation electrode for generating the stimulation signal;

the acquisition unit is electrically connected with the acquisition electrode and is used for receiving the physiological electric signal;

the external machine communication unit is suitable for receiving a control instruction sent by the external machine or sending data to the external machine in a wireless communication mode;

and the implant control unit is used for controlling the respective operations of the implant receiving power supply unit, the stimulation unit, the acquisition unit and the external machine communication unit.

Wherein the extracorporeal host machine may include:

the power supply unit of the external machine is used for supplying power to the external machine;

the power supply unit of the implant is electrically connected with the energy transmitter so as to transmit electric energy to the energy receiver of the implant wirelessly through the energy transmitter;

the implant communication unit is suitable for sending a control instruction to the implant or receiving data sent by the implant in a wireless communication mode;

a storage unit for storing various data and programs;

and the extracorporeal machine control unit is used for controlling respective operations of the extracorporeal machine power supply unit, the implanted body communication unit and the storage unit.

Optionally, the extracorporeal host machine may further include: and the communication unit is suitable for communicating with other equipment in a wired or wireless communication mode.

The utility model discloses in the embodiment, wireless communication mode can include bluetooth, near field communication.

In some embodiments of the invention, the energy transmitter comprises an external resonant coil and the energy receiver comprises an internal resonant coil.

In another embodiment of the present invention, the extracorporeal machine may include: the device comprises a power amplifier, an external machine modulation module, an external machine demodulation module, an external machine DC/DC module and an external machine microcontroller. The external machine modulation module converts information generated by the external machine microcontroller into a digital signal waveform and sends the digital signal waveform to the power amplifier; the DC/DC module of the external machine converts direct-current voltage provided by a power supply of the external machine into power supply voltage suitable for the implant and sends the power supply voltage to the power amplifier; the power amplifier converts the digital signal waveform and the power supply voltage suitable for the implant into a radio frequency waveform and transmits the radio frequency waveform to the implant through the coupling of the in-vitro resonance coil and the in-vivo resonance coil; the external machine demodulation module converts the radio frequency wave containing the information sent back by the implant on the external resonance coil into a digital signal and sends the digital signal to the external machine microcontroller.

Wherein the implant host may include: the implant modulation module, the implant demodulation module, the AC/DC module, the implant DC/DC module and the implant microcontroller. The AC/DC module converts a radio frequency waveform on the in-vivo resonance coil into direct current voltage, and the implant DC/DC module converts the direct current voltage into direct current supply voltage suitable for supplying power to the implant host; the implant demodulation module converts a radio frequency waveform containing information sent by the external machine on the in-vivo resonance coil into a digital signal waveform and sends the digital signal waveform to the implant control unit; the implant modulation module changes the resonance state of the in-vivo resonance coil according to the digital signal generated by the implant microcontroller to generate the radio frequency waveform containing the information sent back by the implant on the in-vitro resonance coil.

In some embodiments of the present invention, the connecting member is adapted to be fixed to an arm, a neck, or a belt of the user.

Adopt the utility model discloses the brain stimulation regulator that each embodiment provided can realize following beneficial effect:

1. the main body part of the implant is implanted under the cortex of the back part of the ear of the user, the electrode is penetrated and led to the lesion part under the skin, the length of the electrode wire is greatly shortened compared with the prior art, and the receiving of interference signals is reduced. Meanwhile, the main body part of the implant is positioned on the head of the user, relative movement caused by the movement of the neck of the user does not exist between the main body of the implant and the electrode, and the electrode wire is positioned on the upper part of the head and cannot deform and move, so that the probability of breakage is greatly reduced, and movement noise cannot be introduced.

2. Compared with the prior art, the route damage caused by arranging the electrode wires is greatly shortened, and the operation and the rehabilitation of patients are facilitated.

3. The implant body portion is implanted under the user's ear posterior cortex without making an incision in the chest. The skull at the back of the ear is smooth in shape and has a certain thickness, and the skull is suitable for grinding bones and cutting a groove for placing a part of the pulse stimulator. The main body part of the implant is flush with the outer surface of the skull without bulges after the operation, and the implant is smooth and without bulges after the skin is restored and sutured, is not stressed, and reduces the possibility of infection and rupture. The cut is covered by hair after recovery, and the beauty is not affected.

4. The battery in the implant is reduced or replaced by a wireless charging mode, and meanwhile, higher internal circuit power consumption is supported, so that more complex circuit functions and wireless communication functions are achieved. The service life of the equipment is greatly prolonged, and the failure caused by the exhaustion of the built-in battery does not exist.

5. Each electrode group comprises a plurality of collecting electrodes and stimulating electrodes, and different electrode groups are placed at different positions of the cortex, so that multi-point collection and stimulation can be realized, or multiple groups of electrodes can be used simultaneously, and a complex electroencephalogram collection and stimulating electrode configuration mode can be realized.

6. The electrode is a cortical electrode (rather than a deep electrode), and the electrode is placed between the dura mater and the bone, and does not cause damage to brain tissue.

7. The energy transmitter and the energy receiver are wirelessly coupled and only carry out energy transmission, so that the transmission efficiency is higher, and the signal transmission and the signal acquisition are not influenced.

8. The external machine and the implant adopt Bluetooth communication, the transmission distance is long, the signal transmission is stable, and the external machine and the implant are not easily interfered.

Drawings

Fig. 1 is a schematic diagram of an application of a conventional cranial nerve regulator.

Fig. 2 is a schematic diagram of an application of a cerebral nerve regulator according to an exemplary embodiment of the present invention.

Fig. 3 is a schematic view of an implant of a cerebral nerve regulator according to an exemplary embodiment of the present invention.

Fig. 4 is a partial cross-sectional view of an implant of a cerebral nerve regulator according to an exemplary embodiment of the present invention.

Fig. 5 is a schematic view of an extracorporeal machine of a cerebral nerve regulator according to an exemplary embodiment of the present invention.

Fig. 6 is a circuit block diagram of a cranial nerve regulator according to an exemplary embodiment of the present invention.

Fig. 7 is a schematic diagram of a cortical electrode implantation in accordance with an exemplary embodiment of the present invention.

Fig. 8 is a circuit block diagram of a cranial nerve regulator according to another embodiment of the present invention.

Detailed Description

Various aspects of the invention are described in detail below with reference to the figures and the detailed description. Well-known components, modules, units and their interconnections, links, communications or operations with each other are not shown or described in detail. Furthermore, the described features, structures, or functions may be combined in any suitable manner in one or more embodiments. It will be understood by those skilled in the art that the various embodiments described below are illustrative only and are not intended to limit the scope of the present invention. It will also be readily understood that the modules or units or processes of the embodiments described herein and illustrated in the figures can be combined and designed in a wide variety of different configurations.

Fig. 2 shows an exemplary application scenario of the cerebral nerve regulator provided by the present invention. In an exemplary embodiment of the present invention, the cranial nerve regulator comprises an implant 1000 and an extracorporeal machine 2000. Wherein the implant 1000 of this embodiment is adapted to be implanted in the cerebral cortex of a user, i.e. a patient, whereas the extracorporeal machine 2000 is placed outside the user's body, unlike the prior art implant 1 shown in fig. 1, which is typically placed subcutaneously in the chest wall.

In an exemplary embodiment of the present invention, as shown in fig. 3, the implant 1000 includes an implant body 1100 adapted to be implanted in the posterior cortex of the user's ear and at least one electrode assembly 1200 adapted to be implanted in the cerebral cortex of any target site of the user. In the exemplary embodiment, implant 1000 includes two electrode sets 1200. The utility model discloses do not do the restriction to this, can set up 1 electrode group according to patient's physiological conditions, also can implant the different positions of cortex with more than 3 electrode groups. The electrode set 1200 may include a stimulation electrode 1201 for outputting a stimulation signal and a collection electrode 1202 for collecting a physiological electrical signal. The electrode assembly 1200 is electrically connected to the implant body 1100, which includes an energy receiver 1120 and an implant host 1110, via an electrode wire 1300.

In an exemplary embodiment of the present invention, as shown in fig. 2 and 5, the external machine 2000 includes an external machine body 2010 and an energy emitter 2020, and the energy emitter 2020 is electrically connected to the external machine body 2010 through a connection wire 2030.

Wherein the energy receiver 1120 is wirelessly coupleable with the energy transmitter 2020 to draw electrical energy from the extracorporeal machine 2000 to power the implant host 1110, and the implant host 1110 is wirelessly communicatively connectable with the extracorporeal host 2010.

In an exemplary embodiment of the present invention, as shown in fig. 4, the implant body main unit 1110, the energy receiver 1120, the electrode wire 1300 and the electrode assembly 1200 are all covered by the silicone gel 1400 satisfying the implant body biocompatibility requirement, and each electrode end of the electrode assembly 1200 is exposed from the silicone gel 1400.

The implant host 1110 includes a bottom housing 1111, a protective cover 1112, an implant circuit board 1113, a power feeding pad 1114, and an antenna 1115 (i.e., an in-vivo antenna implanted in the body during use). Wherein the bottom case 1111 and the protective cover 1112 are combined and define a space for accommodating the implant circuit board 1113 and the feeding pad 1114 inside, the antenna 1115 is disposed outside the bottom case 1111, and the implant circuit board 1113 and the feeding pad 1114 are combined to be electrically connected with the energy receiver 1120, the electrode group 1200 and the antenna 1115 through the feeding pad 1114. The bottom housing 1111, the protective cover 1112, the implant circuit board 1113, the feeding pad 1114, and the antenna 1115 are entirely covered by the silicone 1400.

The energy receiver 1120 includes a magnet 1121 (i.e., an in-vivo magnet implanted in the body in use) and an in-vivo resonant coil 1122, wherein the magnet 1121 is located in a housing 1123 and is surrounded by the in-vivo resonant coil 1122. The housing 1123, the magnet 1121 and the in-vivo resonance coil 1122 are entirely covered with the silicone 1400 and integrally connected to the implant main unit 1110 to constitute an implant main body 1100. Accordingly, as shown in fig. 5, the energy emitter 2020 of the external machine 2000 includes a housing 2023, a magnet 2021 (i.e., a magnet located outside the body in use), and an external resonance coil 2022 surrounding the magnet 2021, the magnet 2021 and the external resonance coil 2022 being located inside the housing 2023. As shown in fig. 2, the energy emitter 2020 and the energy receiver 1120 are fixed by attracting each other by the magnet 1121 and the magnet 2021. The supply voltage is converted into electromagnetic radiation by the external resonance coil 2022 and emitted, and the internal resonance coil 1122 receives the electromagnetic radiation and converts it into a supply voltage to the implant 1000. The utility model discloses in the embodiment, energy transmitter and energy receiver wireless coupling only carry out energy transmission, and transmission efficiency is higher to do not influence signal transmission and signal acquisition.

The electrode wire 1300 is formed by wrapping a metal wire 1301 with a silica gel 1400, and is integrally connected with the implant body host 1110. The electrode wire 1300 is used to electrically connect the electrode assembly 1200 with the implant body host 1110 to transmit stimulation signals and collect data. The electrode group 1200 is a sheet-like or flat member formed by covering each electrode with silicone 1400, and is integrated with the electrode wire 1300, and the motor end is exposed from the silicone 1400 on the flat member. In an exemplary embodiment of the present invention, on the strip-shaped sheet member, i.e., the

electrode group

1200, 2 stimulating electrodes 1201 are close to both ends, and 3 collecting electrodes 1202 are located between the two stimulating electrodes 1201. In an optional embodiment of the present invention, each electrode group may or may not be provided with a collecting electrode according to the needs of the physiological condition of the patient, and the number of the stimulating electrodes and the collecting electrodes may also be set as needed. As shown in fig. 7, electrode 1200 is a cortical electrode (rather than a deep electrode), and is placed between the dura mater and the bone, as shown by wound 3000, without causing damage to the brain tissue.

In an exemplary embodiment of the present invention, the implant body 1100 and the electrode 1200 are formed as an integrated structure by the silicone 1400, so that the unreliable risk caused by the plug connection is reduced.

In an exemplary embodiment of the present invention, for the implant 1100 covered by the silicone, as shown in fig. 4, the thickness of the portion where the implant body 1110 is located is greater than the thickness of the portion where the energy receiver 1120 is located, and the portion where the energy receiver 1120 is located is bent at a predetermined angle with respect to the portion where the implant body 110 is located, the predetermined angle being set to a size that the implant body 1100 fits the shape of the skull at the back of the human ear.

In an exemplary embodiment of the present invention, for the implant 1100 covered by the silicone, the portion of the silicone 1400 where the energy receiver 1120 is located has an opening for taking out and installing the magnet in the body, so that the magnet 1121 can be embedded in the silicone 1400 and also be taken out from the silicone 1400.

The utility model discloses an in the exemplary embodiment, external host computer includes shell, external antenna (promptly, when using, is located the external antenna of user) and external machine circuit board, external machine circuit board is located in the shell, external antenna can set up the inside or the outside of shell, promptly, can be built-in antenna also can be external antenna. As shown in fig. 5, the extracorporeal host 2010 is connected to the energy transmitter 2020 through a connection lead 2030. The connection lead 2030 and the external body host 2010 are connected in a plug-in manner, that is, a jack is formed in a housing of the external body host 2010, the connection lead 2030 is provided with a plug, and the connection lead is connected with the external body host by inserting the plug into the jack. The energy emitter 2020 includes a case 2023, a magnet 2021, and an external resonance coil 2022 surrounding the magnet 2021, the magnet 2021 and the external resonance coil 2022 being located inside the case 2023. As shown in fig. 2, the magnet 2021 and the magnet 1121 attract each other to fix the energy emitter 2020 and the energy receiver 1120 in an adsorption manner. The supply voltage is converted into electromagnetic radiation by the external resonance coil 2022 and emitted, and the internal resonance coil 1122 receives the electromagnetic radiation and converts it into a supply voltage to the implant 1000. In an alternative embodiment, one of the magnet 2021 and the magnet 1121 may be a magnet, and the other may be a member capable of attracting the magnet. In an alternative embodiment, one of the magnet 2021 and the magnet 1121 is a magnet, and the other is a magnet with opposite polarity. In other alternative embodiments, one or both of the magnets 2021 and the magnets 1121 may be omitted, and soft straps may be used to secure the energy emitter in alignment with the energy receiver.

In an exemplary embodiment of the present invention, as shown in fig. 6, the circuit structure of the implant host 1110 may include the following circuit modules:

an implant receiving power supply unit 1001 electrically connected to the energy receiver 1120 to convert the energy received by the energy receiver 1120 from the energy transmitter 2020 into a power supply voltage suitable for the implant host 1110;

a stimulation unit 1002 electrically connected to the stimulation electrode 1201 for generating a stimulation signal;

an acquisition unit 1003 electrically connected to the acquisition electrode 1202 and configured to receive the physiological electrical signal sensed by the acquisition electrode 1202;

an external machine communication unit 1004 electrically connected to the antenna 1115 and adapted to receive a control command transmitted from the external machine 2000 or transmit data to the external machine 2000 via the antenna 115;

a control unit 1005 (i.e., an implant control unit) for controlling respective operations of the implant reception power supply unit 1001, the stimulation unit 1002, the acquisition unit 1003, and the external machine communication unit 1004.

In an exemplary embodiment of the present invention, the control unit 1005 of the implant is responsible for controlling the system functions of the entire implant and communicates with the extracorporeal machine 2000 by communicating with the extracorporeal machine communication unit 1004. The control unit 1005 may receive a control command of the extracorporeal unit 2000 to control the collecting unit 1003 and the stimulating unit 1002. The control unit 1005 may also analyze the collected data by an algorithm and actively initiate stimulation by the stimulation unit 1002 according to the analysis result. In an exemplary embodiment of the present invention, the control unit 1005 may be implemented by a single chip microcomputer or the like.

In an optional embodiment of the present invention, the implant host 1110 may further include a secondary battery, for example, a lithium ion battery, for accumulating the electric energy received by the energy receiver.

In an exemplary embodiment of the present invention, part or all of the implant receiving power supply unit 1001, the stimulation unit 1002, the acquisition unit 1003, the external machine communication unit 1004, and the control unit 1005 are disposed on the implant circuit board 1113.

In an exemplary embodiment of the present invention, as shown in fig. 6, the extracorporeal host 2010 may include the following circuit modules:

an extracorporeal machine power supply unit 2001 for supplying power to the extracorporeal machine, which may be powered by a battery or a USB;

an implant powering unit 2002 electrically connected to the energy transmitter 2020 to wirelessly transmit electrical energy through the energy transmitter 2020 to an energy receiver 1120 of the implant 1000;

an implant communication unit 2003 electrically connected to the external antenna and adapted to transmit control commands to the implant 1000 or receive data transmitted by the implant 1000 through the external antenna;

a storage unit 2004 for storing various data;

a control unit 2005 (i.e., an extracorporeal machine control unit) for controlling respective operations of the extracorporeal machine power supply unit 2001, the implant power supply unit 2002, the implant communication unit 2003, and the storage unit 2004.

In an optional embodiment of the present invention, the extracorporeal host further comprises an external device communication unit 2006 adapted to communicate with other devices in a wired or wireless communication manner.

In an exemplary embodiment of the present invention, the extracorporeal machine control unit is used to control the operation of the system of the whole extracorporeal machine. For example, receiving commands from an external device, sending commands to the implant, receiving and processing data sent by the implant, controlling whether to start/stop the power supply to the implant, etc. In an exemplary embodiment of the present invention, the control unit 2005 can be implemented by a single chip microcomputer or the like.

In an exemplary embodiment of the present invention, the implant 1000 communicates with the extracorporeal machine 2000 and/or the extracorporeal machine 2000 communicates with other external devices via bluetooth. The bluetooth transmission distance is long and signal transmission is stable, is difficult for receiving the interference. In an optional embodiment of the present invention, the devices may also communicate with each other using NFC (near field communication).

In an exemplary embodiment of the present invention, some or all of the extracorporeal power supply unit 2001, the implant power supply unit 2002, the implant communication unit 2003, the storage unit 2004, the control unit 2005, and the external device communication unit 2006 are disposed on the extracorporeal circuit board.

In some embodiments of the present invention, the extracorporeal machine main unit may have a connection part adapted to be fixed to the arm or neck or belt of the user, for example, a strap, a hanging rope, a clip, etc.

In some embodiments of the present invention, the extracorporeal machine may have an electric quantity indicator thereon.

In some embodiments of the present invention, the body external machine may have an alarm adapted to alarm when the body external machine is disconnected from the body internal machine. For example, the extracorporeal control unit triggers an alarm when it detects that the energy transmitter is disconnected from the energy receiver or the wireless communication connection is disconnected.

In some embodiments of the present invention, a debugging interface is disposed on the extracorporeal machine.

In some embodiments of the present invention, the extracorporeal power supply unit 2001 includes a secondary battery, for example, a lithium ion battery.

The utility model discloses the implant main part of embodiment implants user's behind the ear subcutaneous, hugs closely the skull. The skull at the back of the ear is smooth in shape and has a certain thickness, and the skull is suitable for grinding bones and cutting a groove for placing a part of the pulse stimulator. The main body part of the implant is flush with the outer surface of the skull without bulges after the operation, and the skin is smooth and without bulges after the recovery and the suture. The cut is covered by hair after recovery, and the beauty is not affected. The electrodes are placed in close proximity to the appropriate area of the intracranial cortex of the user. An energy transmitter (an external resonance coil) of the external machine is adsorbed on the head of a user through magnetic force, aligned and coupled with an energy receiver (an internal resonance coil), and the external machine supplies power for an implant through the external resonance coil.

Fig. 8 shows another embodiment of the present invention. As shown in fig. 8, in the present embodiment, the cranial nerve regulator includes an extracorporeal motor and an implant, similar to fig. 2. The difference from the previous exemplary embodiments is that the extra-corporeal unit and the implant are magnetically coupled for power supply and communication by the resonant coil. In other words, in this embodiment, the wireless communication method is a radio frequency communication method. The differences are described in detail below, and other identical or similar components and processes are not described in detail.

In this embodiment, the external machine includes an external machine main body and a resonance coil 816 (i.e., an external resonance coil), wherein the resonance coil 816 and the external resonance coil 2022 may have the same configuration. The extracorporeal host machine may include: MCU811 (i.e., an external machine microcontroller), adjustable DC/DC812 (i.e., an external machine DC/DC module), Class E (Class E) power amplifier 813, modulation module 814 (i.e., an external machine modulation module), and demodulation module 815 (i.e., an external machine demodulation module).

The implant includes an implant body main unit and a resonance coil 826 (i.e., an in-vivo resonance coil), wherein the resonance coil 826 and the in-vitro resonance coil 1122 may have the same configuration. The implant host may include: an MCU 821 (i.e., implant microcontroller), an implant AC/DC 822, an implant DC/DC 823, a modulation module 824 (i.e., implant modulation module), and a demodulation module 825 (i.e., implant demodulation module).

In one aspect, in the extracorporeal machine, the MCU811 is responsible for generating information to be transmitted (e.g., stimulation commands), the modulation module 814 converts the information to be transmitted into a corresponding digital signal waveform and transmits the digital signal waveform to the Class E power amplifier 813, the Class E power amplifier converts the digital signal waveform into a corresponding radio frequency waveform, for example, the modulation module 814 generates a driving signal of the power amplifier according to the digital signal waveform, so that the power amplifier outputs the modulated radio frequency waveform, and transmits the modulated radio frequency waveform to the implant demodulation module 825 through the wireless coupling (specifically, magnetic coupling) between the resonant coil 816 and the resonant coil 826. And the adjustable DC/DC812 can generate adjustable DC voltage according to the power supply of the external machine, the voltage is directly supplied to the Class E power amplifier 813, the Class E power amplifier 813 outputs radio frequency waveforms with different amplitudes to the resonant coil 816 by outputting different voltages, and the electric energy is sent to the implant through the magnetic coupling of the resonant coil 816 and the resonant coil 826. Thus, the power amplifier may generate a radio frequency waveform containing information sent by the extracorporeal machine to the implant and transmitted to resonant coil 826 by magnetic coupling.

In the implant, the RF waveform on the resonant coil 826 is converted to a DC voltage by the implant AC/DC 822, and converted to a DC voltage suitable for the other circuitry of the implant via the implant DC/DC 823. On the other hand, the demodulation module 825 demodulates the radio frequency waveform on the resonant coil 826 to obtain a digital signal waveform, and transmits the digital signal waveform to the MCU 821 to obtain corresponding information, such as a stimulation command, after an operation process. Thus, information transmission and power supply are realized by magnetic coupling.

On the other hand, in the implant, the modulation module 824 transmits information that the implant needs to be transmitted back to the extracorporeal machine (for example, the acquired data acquired by the acquisition electrode is transmitted to the modulation module 824 through the MCU 821) to the demodulation module 815 of the extracorporeal machine through magnetic coupling between the resonant coil 826 and the resonant coil 816 after modulation processing, for example, the modulation module 824 changes the resonance state (for example, the resonance frequency) of the resonant coil 826 according to the digital signal waveform output by the MCU 821, so that the radio frequency waveform generated on the resonant coil 816 includes the information that the implant needs to be transmitted back to the extracorporeal machine. The demodulation module 815 demodulates the radio frequency waveform to obtain a digital signal waveform that can be identified by the MCU811, and the digital signal waveform is processed by the MCU to obtain corresponding information and sent to the MCU 811.

Adopt the utility model discloses cranial nerve regulator of embodiment, its mode through the resonance coil magnetic coupling realizes energy transmission and information (including stimulation instruction and collection data) transmission in the lump for the circuit configuration of implant compares and simplifies more in extra wireless communication transmission. Further, since only magnetic coupling is performed by the resonance coil, and there is no ionization signal, transmission is more stable (less affected by the surrounding environment, particularly in human body environments such as muscle and physiological saline).

Various aspects of the present invention have been described in detail above with respect to various embodiments. It should be understood by those skilled in the art that the foregoing is only illustrative of the embodiments of the present invention, and that the scope of the invention is not limited thereto.

Claims

1. A cranial nerve regulator is characterized by comprising an implant body and an extracorporeal machine which is communicated with the implant body in a wireless communication mode;

2. The brain neuromodulator of claim 1 wherein the electrode set comprises a stimulation electrode for outputting the stimulation signal and a collection electrode for collecting the physiological electrical signal.

3. The cranial nerve regulator of claim 2, wherein the implant host comprises the following circuit modules:

4. The cranial nerve regulator of claim 3, wherein the extracorporeal host comprises:

a storage unit for storing various data;

5. The cerebral neuromodulator of claim 4 wherein the extracorporeal host further comprises: and the communication unit is suitable for communicating with the external equipment in a wired or wireless communication mode.

6. The neuroregulator of claim 1, wherein the wireless communication means comprises bluetooth, near field communication.

7. The cranial nerve modulator of claim 1, wherein the energy transmitter comprises an external resonant coil and the energy receiver comprises an internal resonant coil.

8. The cerebral neuromodulator of claim 7 wherein the extracorporeal host comprises: the system comprises a power amplifier, an external machine modulation module, an external machine demodulation module, an external machine DC/DC module and an external machine microcontroller;

the external machine modulation module converts information generated by the external machine microcontroller into a digital signal waveform and sends the digital signal waveform to the power amplifier;

the DC/DC module of the extra-corporeal machine converts the direct-current voltage provided by the power supply of the extra-corporeal machine into the power supply voltage suitable for the implant and supplies the power supply voltage to the power amplifier;

the power amplifier converts the digital signal waveform and the power supply voltage suitable for the implant into a radio frequency waveform and transmits the radio frequency waveform to the implant through the wireless coupling of the in-vitro resonance coil and the in-vivo resonance coil;

the external machine demodulation module converts the radio frequency wave containing the information sent back by the implant on the external resonance coil into a digital signal waveform and sends the digital signal waveform to the external machine microcontroller.

9. The cranial nerve regulator of claim 8, wherein the implant host comprises: the implant modulation module, the implant demodulation module, the AC/DC module, the implant DC/DC module and the implant microcontroller;

the AC/DC module converts a radio frequency waveform on the in-vivo resonance coil into direct current voltage, and the implant DC/DC module converts the direct current voltage into direct current supply voltage suitable for supplying power to the implant host;

the implant demodulation module converts a radio frequency waveform containing information sent by the external machine on the in-vivo resonance coil into a digital signal waveform and sends the digital signal waveform to the implant control unit;

and the implant modulation module changes the resonance state of the in-vivo resonance coil according to the digital signal waveform generated by the implant microcontroller to generate the radio frequency waveform containing the information sent back by the implant on the in-vitro resonance coil.

10. The cranial nerve regulator of claim 1, wherein the external host machine is provided with a connecting part adapted to be fixed to an arm or neck or a belt of the user.