CN212433040U - Removable denture - Google Patents

Abstract

The utility model belongs to the technical field of novel oral cavity artificial tooth design, especially, relate to a can pluck artificial tooth, upper jaw movable artificial tooth has the cell body including the base, opens on the plane of base, installs signal emission module and sensor group in the cell body, every sensor in the sensor group all includes in proper order: an analyte collection layer, an insulating layer, and a substrate, a compound targeting layer embedded on the insulating layer, a data transmission layer disposed between the insulating layer and the substrate; and the data transmission layer is connected with an electrode layer. The sensor has the advantages of simple structure, high sensitivity, stability, quick response and water resistance, and can improve the consciousness of people for preventing and controlling the three-high disease in daily life.

Description

Removable denture

Technical Field

The utility model belongs to the technical field of novel oral cavity artificial tooth design, especially, relate to a removable artificial tooth.

Background

With the increase of the aging population in China, the oral cavity problems of the aged population are more and more emphasized, wherein the phenomena of dentition defect or dentition deletion are common, and removable partial dentures and complete dentures become the main body of repair treatment. Meanwhile, the old people are also susceptible to hyperglycemia, hypertension and hyperlipidemia. Wherein, the intake of sodium salt is positively correlated with the prevalence rate of hypertension, the daily salt intake of normal people is preferably not more than 6g, the intake of salt is strictly controlled in the prevention and treatment of hypertension, otherwise, hypertension is easy to cause cardiovascular and cerebrovascular diseases. Glucose is a main vital characteristic compound, has an important position in the biological field, and is an important intermediate product of energy sources and metabolism of organisms, so that the detection and analysis of glucose plays an important role in the diagnosis, treatment and control of human health and diseases. Many studies have demonstrated a correlation between blood glucose and salivary glucose levels, and direct application of salivary glucose measurements to show the health status of an individual is theoretically possible and appears to be achievable. It is extremely important to reduce and control the glucose intake to avoid circulatory problems (renal failure, cardiovascular disease, retinopathy, etc.) in time, which are caused by diabetes. Hyperlipidemia has few symptoms in the early stage, and causes cardiac dysfunction in severe cases. The daily diet can control fat intake, and prevent and control hyperlipidemia in advance. Therefore, the intake of salt, glucose and fat should be controlled properly to prevent and control the development of diseases.

SUMMERY OF THE UTILITY MODEL

The technical problem to be solved by the utility model is to provide a removable denture, which has the advantages of simple structure, high sensitivity, stability, fast response and water resistance, and can not only improve the consciousness of people for preventing and controlling the diseases of three highs in daily life.

The utility model discloses a realize like this, a can pluck artificial tooth, including upper jaw movable artificial tooth and lower jaw movable artificial tooth, upper jaw movable artificial tooth is including the base, and it has the cell body to open on the plane of base, installs signal emission module and sensor group in the cell body, every sensor in the sensor group all includes in proper order: an analyte collection layer, an insulating layer, and a substrate, a compound targeting layer embedded on the insulating layer, a data transmission layer disposed between the insulating layer and the substrate; and the data transmission layer is connected with an electrode layer.

Further, a circular passivation layer is embedded on the insulating layer.

Furthermore, the data transmission layer is two layer bodies with circular structures, and the two electrode layers are matched with the data transmission layer and are provided with leading-out terminals.

Further, the sensor group includes: a salt sensor, a glucose sensor, and a fat sensor.

Further, the analyte collection layer employs a paper substrate.

Further, the insulating layer is a mold-molded thin film PDMS.

Further, the data transmission layer is a conductive silver adhesive layer.

Further, the passivation layer is an aluminum film.

Further, the substrate is a polyimide film.

Compared with the prior art, the utility model, beneficial effect lies in: the utility model comprises a maxillary denture base and three independent sensors embedded therein, namely a salt sensor, a glucose sensor and a fat sensor. The main structures of the sensing element of the biosensor are a base electrode layer, an insulating layer, a data transmission layer, a biomarker targeting layer, a passivation layer and an analyte collection layer. After food is eaten, the sensor group respectively collects concentration information of the target compounds in saliva, the mobile terminal processes and analyzes data information to calculate the intake of salt, glucose and fat, and judges whether the intake is in a recommended range, if the intake is unreasonable, an audio alarm is sent to remind a wearer of paying attention to control the intake, and the eating habit is improved. The sensor has the advantages of simple structure, high sensitivity, low working voltage, stability, quick response and water resistance, and can improve the consciousness of people for preventing and controlling three-high diseases in daily life, particularly the elderly with defective or missing dentition; and the data can be transmitted to doctors or dieticians to reasonably regulate the diet requirements.

Drawings

Fig. 1 is a horizontal section structure diagram of an upper jaw removable denture provided with salt, glucose and fat sensors according to an embodiment of the present invention;

fig. 2 is a vertical sectional structure view of an upper jaw removable denture equipped with salt, glucose and fat sensors according to an embodiment of the present invention;

fig. 3 is a perspective view of a sensor according to an embodiment of the present invention;

fig. 4 is a circuit block diagram of a sensor provided by an embodiment of the present invention;

the labels in the figures are: 1 maxillary removable denture, 2 signaling module, 3 sensor group, 31 analyte collection layer, 32 passivation layer, 33 compound targeting layer, 34 insulating layer, 35 data transmission layer, 36 electrode layer, 37 substrate.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

As shown in fig. 1 in combination with fig. 2 and 3, a removable denture comprises an upper jaw removable denture and a lower jaw removable denture, wherein the upper jaw removable denture comprises a base, a groove body is formed on the plane of the base, a signal transmitting module 2 and a sensor group 3 are arranged in the groove body, and each sensor in the sensor group sequentially comprises: an analyte collection layer 31, an insulating layer 34, and a substrate 37, with a compound targeting layer 33 embedded on the insulating layer, and a data transmission layer 35 disposed between the insulating layer and the substrate; an electrode layer 36 is connected to the data transmission layer 35.

A circular passivation layer 32 is embedded on the insulating layer.

The data transmission layer is two layer bodies with circular structures, and the two electrode layers are matched with the data transmission layer and are provided with leading-out ends.

The sensor group includes: a salt sensor, a glucose sensor, and a fat sensor.

The sensor is embedded in the base, so that the appearance and the function of the denture base are not influenced. When the complete denture is worn, the power supply and the signal emitting module 2 are turned on, the analyte collecting layers 31 of the sensor group 3 respectively collect saliva containing analytes, the compound targeting layer 33 obtains the concentration information of the targeting compound, the sensor group collects the concentration information of the targeting compound after the data transmission layer 35 transmits the data information to the sensors, and the information is sent to the mobile terminal.

The novel power supply and signal transmitting module is placed in a groove body. The signal transmitting module and the sensor group are powered and adopt waterproof and electricity-proof settings.

The circuit block diagram adopted is shown in figure 4,

this neotype use does: the method comprises the steps of wearing an upper jaw removable denture provided with salt, glucose and fat sensors, collecting concentration information of a target compound through the salt, glucose and fat sensors after food intake is finished, sending the information to a mobile terminal through a signal transmitting module, calculating and analyzing data by the mobile terminal (by adopting a mobile phone), calculating the intake of the salt, glucose and fat at this time by combining concentration and maintenance time, comparing the intake with recommended intake, displaying diet health when the intake is within a reasonable range, and sending an audio alarm when the intake exceeds the recommended intake to remind of controlling the intake of a certain substance.

The manufacturing process of the novel sensor comprises the following steps:

preparation of glucose sensor: the gold electrode (diameter 2.0mm) was polished to a mirror surface with polishing powder and then ultrasonically cleaned for 5 min. And soaking the gold electrode in the L-Cys solution for 4h, taking out the gold electrode, washing the gold electrode with secondary distilled water to prepare the L-Cys modified gold electrode, and then sequentially soaking the Au @ Ag/PPy dispersion solution for 12h and the glucose oxidase solution for 12h to obtain the enzyme modified electrode. The GOD fixed by the L-Cys/Au @ Ag/PPy has obvious electrocatalytic activity on glucose, and as the concentration of the glucose is increased, the peak current flowing on the L-Cys/Au @ Ag/PPy/GOD modified electrode under the same voltage is increased. Therefore, the glucose concentration in the environment can be effectively detected. The sensor has high sensitivity, wide linear range, high stability and good repeatability.

Preparation of a salt sensor: specifically, to form an ion-selective membrane, a Na + selective membrane mixture was drop cast onto a PEDOT: (ii) a PSS electrode. Solid silver/silver chloride (Ag/AgCl) was made as a reference electrode and coated with polyvinyl butyral to ensure reliable readings. The open circuit potential change is measured using a potentiostat to indicate the change in ion concentration. The device consists of off-the-shelf chip components (e.g., micro bluetooth ICs, rechargeable batteries and other signal processing units) and stretchable interconnects encased in a flexible elastomeric casing (0.2-0.5 mm thick silicone rubber) that can be passivated. A flexible, low-profile device is mounted on the micropore fixture to achieve breathability and low thermal load upon contact with oral tissue. An inexpensive and rapidly responding ion selective sodium electrode (ISE) consisting of a plated Pd working electrode and an Ag/AgCl reference electrode can accurately measure sodium ion uptake.

Preparing a fat sensor: chitosan, nano gold sol, GPR120 protein solution, thionine-chitosan mixture, horseradish peroxidase-nano gold sol and GPR120 protein solution are sequentially fixed on the surface of the glassy carbon electrode by a self-assembly method, and finally, the glassy carbon electrode is sealed by BSA solution. Each process of assembly was characterized using cyclic voltammetry, and the concentration of fatty acids in saliva was measured separately by time-current method. The sensor has good reproducibility and stability.

The three electrochemical sensors have different functions, namely selectivity of an electrode layer and a compound targeting layer to corresponding chemical substances, the material of an analyte collecting layer is a paper base material with good water absorption and is used for maintaining proper saliva quantity, an insulating layer is a film PDMS formed by a mold and is used for protecting an electrode and a circuit and preventing short circuit, a data transmission layer is conductive silver adhesive with low resistivity and plays a role in amplifying signals, and a passivation layer is made of an aluminum film with a surface treated by concentrated acid and is used for protecting metal materials in the sensor from being corroded. The material of the substrate is a polyimide film with good flexibility and biocompatibility.

The above description is only exemplary of the present invention and should not be taken as limiting the scope of the present invention, as any modifications, equivalents, improvements and the like made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.

Claims (9)

1. A removable denture comprises an upper jaw removable denture and a lower jaw removable denture, and is characterized in that the upper jaw removable denture comprises a base, a groove body is formed in the plane of the base, a signal transmitting module and a sensor group are installed in the groove body, and each sensor in the sensor group sequentially comprises: an analyte collection layer, an insulating layer, and a substrate, a compound targeting layer embedded on the insulating layer, a data transmission layer disposed between the insulating layer and the substrate; and the data transmission layer is connected with an electrode layer.

2. A removable denture according to claim 1, wherein a rounded passivation layer is embedded on said insulating layer.

3. A removable denture according to claim 1, wherein said data transfer layer is two layers of circular configuration, and two electrode layers are provided, cooperating with said data transfer layer and having terminals.

4. A removable denture according to claim 1, wherein said sensor set comprises: a salt sensor, a glucose sensor, and a fat sensor.

5. A removable denture according to claim 1, wherein said analyte collecting layer comprises a paper substrate.

6. A removable denture according to claim 1, wherein the insulation layer is a molded film of PDMS.

7. A removable denture according to claim 1, wherein said data transfer layer is a conductive silver paste layer.

8. A removable denture according to claim 1, wherein the passivation layer is an aluminum film.

9. A removable denture according to claim 1, wherein the substrate is a polyimide film.

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