CN212383609U - Test specimen preprocessing device - Google Patents

Test specimen preprocessing device Download PDF

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Publication number
CN212383609U
CN212383609U CN202021785751.6U CN202021785751U CN212383609U CN 212383609 U CN212383609 U CN 212383609U CN 202021785751 U CN202021785751 U CN 202021785751U CN 212383609 U CN212383609 U CN 212383609U
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ball
fixedly connected
liquid
mixing
sample
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李利娟
丁利霞
贾全胜
徐永新
谷晓辉
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Zhengzhou Jinyu Clinical Testing Center Co ltd
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Zhengzhou Jinyu Clinical Testing Center Co ltd
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Abstract

The utility model discloses an inspection sample preprocessing device belongs to sample preprocessing technical field, the utility model discloses can be in batches to carrying out orderly black space to the whole sample mixture liquid that adds sample and reagent and deposit and regularly, and realize the quantitative application of sample of the same kind of reagent batch, improve and divide liquid efficiency, still assist the mixing to multiple mixture liquid after the application of liquid simultaneously, mixed liquid reaction efficiency has been improved greatly, guarantee the accuracy of inspection result, change the series operation among the traditional manual operation into mechanical parallel operation, save operating time, avoid endangering staff's personal safety simultaneously, the device not only can be applicable to the aspect of flow cytometry, use and other needs add equivalent same kind of reagent in batches. Meanwhile, the problem that the samples after being added with samples are stored in different places can be solved, personnel need to spend energy in different places to find the samples for further processing, or extra cost is increased in a laboratory to build a darkroom, and the laboratory effective space can be utilized by using the whole device.

Description

Test specimen preprocessing device
Technical Field
The utility model relates to a sample preprocessing technical field, more specifically say, relate to an inspection sample preprocessing device.
Background
Before the detection of the flow cytometry specimen, firstly, a laboratory worker adds the specimen and the corresponding monoclonal antibody according to a preset project, the specimen and the corresponding monoclonal antibody are manually shaken up, then the specimen and the antibody are fully combined for a period of time (timer setting time) in a dark space, the artificial single specimen is added with a hemolytic agent with a certain volume one by one, the specimen is fully mixed and mixed again, then the specimen is fully hemolyzed in the dark space again, and after the specimen is placed for a period of time (timer setting time), subsequent centrifugation is carried out, and the treatment and the detection are carried out. The large-scale laboratory uses the flow type workstation to have the sample processing apparatus, belongs to the part of workstation, and efficiency is higher, but the cost is too high, has restricted its use in the flow type laboratory for the sample processing in flow type laboratory still is in manual stage.
In recent years, flow cytometry is more and more widely applied to medical laboratories, the manual treatment of flow cytometry samples wastes time and labor, the efficiency is low, and the manual treatment becomes a great obstacle for improving the efficiency of flow laboratories, the time consumption means that the samples can be shaken up after being placed in a dark room every time, the number of sample tubes which can be taken by hands every time is limited, the samples need to be carried out for multiple times, and the hemolytic agent is added to each sample tube one by one, so that the efficiency is influenced; hard is when shaking at the manual sample of taking at every turn, needs personnel to tightly hold the sample, prevents that the sample from dropping and spilling hourglass, causes the sample can't continue to detect, in case the sample drops and causes biological hazard to the staff easily, and causes the sample can't continue to detect. On the other hand, the darkroom needs to be additionally built or placed in a dark space such as a drawer, the additional building of the darkroom increases the operation cost of the laboratory, increases the influence on the efficiency of the personnel walking back and forth, and the drawer and other storage methods only can solve the storage problem but cannot solve the efficiency problem. The device is specially developed based on the problems so as to quickly and simply carry out pretreatment and improve the efficiency.
SUMMERY OF THE UTILITY MODEL
1. Technical problem to be solved
Problem to exist among the prior art, an object of the utility model is to provide an inspection sample preprocessing device, it can be in batches to carrying out orderly black space to the whole sample mixture liquid that adds sample and reagent and deposit and regularly, and realize the quantitative application of sample of same kind reagent in batches, improve and divide liquid efficiency, the while still mixes liquid to the multiple after the liquid addition and assists the mixing, mixed liquid reaction efficiency has been improved greatly, guarantee the accuracy of inspection result, change the series operation among the traditional manual operation into mechanical parallel operation, save operating time, avoid endangering staff's personal safety simultaneously, the device not only can be applicable to the aspect of flow cytometry, do use and other needs add same kind of reagent of equivalent in batches. Meanwhile, the problem that the samples after being added with samples are stored in different places can be solved, personnel need to spend energy in different places to find the samples for further processing, or extra cost is increased in a laboratory to build a darkroom, and the laboratory effective space can be utilized by using the whole device.
2. Technical scheme
In order to solve the above problems, the utility model adopts the following technical proposal.
The utility model provides a test specimen preprocessing device, includes liquid distribution device, timing indicating device and vibrates mixing device, liquid distribution device includes reagent bottle and the room of keeping in, be connected with the transfer pipe between reagent bottle and the room of keeping in, the both ends of transferring the pipe extend to the inside of reagent bottle and the room of keeping in respectively, the inside sliding connection of reagent bottle has built-in pressure pad, the upper end fixedly connected with pressure bar of built-in pressure pad, the inside of reagent bottle holds hemolytic agent, the upper liquid level of hemolytic agent contacts with the lower bottom surface of built-in pressure pad, the upper end fixedly connected with control panel of the room of keeping in, the lower extreme fixedly connected with a plurality of evenly distributed's of joint pipes of the room of keeping in, the lower extreme fixedly connected with liquid separation rifle head of joint pipe, fixedly connected with test tube inductor on the joint pipe, vibrate mixing device including connecting in the processing case of the room lower extreme of keeping in, the joint pipe penetrates through the upper end of the treatment box and extends to the inside of the treatment box, a plurality of oscillators are arranged inside the treatment box, a plurality of lifting devices which are uniformly distributed are fixedly connected to the lower ends of the oscillators, a test tube rack is placed on the upper ends of the oscillators, a plurality of buckles which are connected with the test tube rack in a clamping manner are fixedly connected to the upper ends of the oscillators, and a multi-node shock-inducing and mixing string chain is arranged inside the liquid separating gun head, so that the utility model can store and time the whole sample mixed liquid added with the sample and the reagent in a orderly black space, realize the batch quantitative storage of the same reagent, improve the liquid separating efficiency, and simultaneously assist and mix the multiple mixed liquids after liquid adding, greatly improve the reaction efficiency of the mixed liquid, ensure the accuracy of the inspection result, change the series operation in the traditional manual operation into the mechanical parallel operation, and save the operation time, simultaneously, the personal safety of workers is avoided from being endangered, and the device not only can be suitable for the aspect of flow cytometry, but also can be used for adding the same reagent with the same quantity in batches as other reagents needing to be added. Meanwhile, the problem that the samples after being added with samples are stored in different places can be solved, personnel need to spend energy in different places to find the samples for further processing, or extra cost is increased in a laboratory to build a darkroom, and the laboratory effective space can be utilized by using the whole device.
Further, timing indicator includes that a plurality of rotations are connected in the darkroom door of handling the case outer end, the outer end fixedly connected with handle, timer, pilot lamp, lifting switch and the shock switch of darkroom door, test tube inductor, timer and pilot lamp all with control face screen electric connection, oscillator and lifting switch electric connection press the lifting switch and can start the oscillator, lifting device and shock switch electric connection press the shock switch and can start elevating gear, when the timer starts (the pilot lamp becomes red and sets up, daily not user state is not bright), regularly accomplish the pilot lamp and become green, the staff can in time carry out next step work according to the colour change.
Furthermore, the multi-node vibration inducing and mixing string chain comprises a connecting rope positioned in the liquid separating gun head, a pair of limiting end balls and a plurality of rebound cyclone balls are fixedly connected to the connecting rope, the plurality of rebound cyclone balls are uniformly distributed between the pair of limiting end balls, the inner top end of the temporary storage chamber is fixedly connected with a plurality of reels, the upper end of the connecting rope penetrates through the inside of the joint pipe until the upper end of the connecting rope is fixedly connected with the outer ends of the reels, the winder is electrically connected with the control panel, when in liquid separation, the multi-node vibration-inducing mixing string chain extends downwards to the corresponding test tube and enters the mixed liquid, when the test tube of the oscillator is started to vibrate, the multi-node vibration inducing and mixing chain is contacted with the inner wall of the test tube to realize the transmission of vibration, the multi-node vibration inducing and mixing string chain vibrates in the mixed liquid and collides with the mixed liquid, so that the mixing effect of the mixed liquid can be further enhanced.
Further, the rebound cyclone ball comprises an inner ball fixedly connected to the outer end of the connecting rope, an outer cyclone ball is arranged on the outer side of the inner ball, a ball groove is formed in the outer cyclone ball, wire holes are formed in the upper inner wall and the lower inner wall of the ball groove, the inner ball is rotatably connected to the inner portion of the ball groove, the connecting rope is located in the wire holes, a plurality of elastic soft rods which are uniformly distributed are fixedly connected to the outer end of the outer cyclone ball, when the multi-node induced vibration mixing and mixing chain vibrates, the rebound cyclone ball rocks back and forth in the mixed liquid, when the rebound cyclone ball is in contact collision with the inner wall of the test tube, the elastic soft rods are firstly extruded to generate bending deformation, under the elastic action of the elastic soft rods, the rebound cyclone ball rebounds to rock again, and when the rebound cyclone ball rocks, the outer cyclone ball does irregular rotary motion around the inner ball due to self-rocking and the vibration of the mixed liquid, make the soft stick of elasticity stir mixed liquid again to shake and rotary motion through the elasticity of making a round trip of resilience whirlwind ball, can realize dual stirring to mixed liquid, further accelerate mixing speed and the effect of mixed liquid.
Further, it is a pair of still be equipped with the anti-overflow ball between the spacing end ball, circular passageway has been seted up on the anti-overflow ball, even the rope is located circular passageway's inside, and the anti-overflow ball can realize the shutoff to the test tube open end, makes mixed liquid in vibrations mixing process, is difficult for following the test tube opening part spill.
Further, the diameter of spacing end ball is greater than the aperture of circular passageway for the moving range of anti-overflow ball is between a pair of spacing end ball, the biggest outer lane diameter of resilience whirlwind ball is less than the aperture of circular passageway, makes things convenient for resilience whirlwind ball and even rope to reciprocate in circular passageway is inside, thereby makes things convenient for the multinode to draw the extension of shaking the mixing string chain and withdraw, the lower extreme liquid outlet bore of dividing the liquid rifle head is between spacing end ball diameter and anti-overflow ball diameter, and spacing end ball can get into the inside of dividing the liquid rifle head, and convenient multinode draws shakes the mixing string chain and withdraws from the test tube, and, when the multinode draws the mixing string chain of shaking to withdraw completely, the anti-overflow ball stops in the liquid outlet department of dividing the liquid rifle head.
Furthermore, the elastic soft rod is made of soft rubber materials, so that the rebound cyclone ball is in contact with the inner wall of the test tube to elastically rebound, and the test tube is not easily damaged by collision.
3. Advantageous effects
Compared with the prior art, the utility model has the advantages of:
(1) this scheme can be in batches to the whole sample mixed liquid that adds sample and reagent carry out ordered black space and deposit and regularly, and realize the quantitative application of sample of same race in batches, improve and divide liquid efficiency, the while still mixes the liquid and assists the mixing to multiple mixture after the liquid feeding, mixed liquid reaction efficiency has been improved greatly, guarantee the accuracy of inspection result, change the series operation in traditional manual operation into mechanical parallel operation, save operating time, avoid endangering staff personal safety simultaneously, the device not only can be applicable to the aspect of flow cytometry, it adds same race of equivalent with other needs in batches to do the use. Meanwhile, the problem that the samples after being added with samples are stored in different places can be solved, personnel need to spend energy in different places to find the samples for further processing, or extra cost is increased in a laboratory to build a darkroom, and the laboratory effective space can be utilized by using the whole device.
(2) Timing indicating device includes that a plurality of rotations are connected in the darkroom door of handling the case outer end, the outer end fixedly connected with handle of darkroom door, the timer, the pilot lamp, lifting switch and shock switch, the test tube inductor, timer and pilot lamp all with control face screen electric connection, oscillator and lifting switch electric connection, press lifting switch startable oscillator, lifting device and shock switch electric connection, press shock switch startable elevating gear, when the timer starts (the pilot lamp becomes red and sets up, daily not in service behavior is not bright), regularly accomplish the pilot lamp and become green, the staff can in time carry out next step work according to the colour change.
(3) The multinode draws shakes mixing string chain including lieing in the inside company rope that divides liquid gun head, a pair of spacing end ball of fixedly connected with and a plurality of resilience whirlwind ball on even the rope, a plurality of resilience whirlwind ball evenly distributed are between a pair of spacing end ball, the interior top end fixedly connected with a plurality of reels of room of keeping in, the inside of even upper end run-through joint pipe of rope is until the outer end fixed connection with the reel, reel and control surface screen electric connection, during the branch liquid, the multinode draws shakes mixing string chain downwardly extending to during corresponding test tube, get into in the mixed liquid, when starting the vibrations of oscillator test tube, the multinode draws the transmission that shakes mixing string chain and test tube inner wall contact and realized vibrations, draw the mixing string chain to shake in the mixed liquid through the multinode, collide with mixed liquid, can further strengthen the mixed effect of mixed liquid.
(4) The resilience cyclone ball comprises an inner ball fixedly connected with the outer end of the connecting rope, an outer cyclone ball is arranged on the outer side of the inner ball, a ball groove is formed in the outer cyclone ball, wire holes are formed in the upper inner wall and the lower inner wall of the ball groove, the inner ball is rotatably connected in the ball groove, the connecting rope is positioned in the wire holes, a plurality of elastic soft rods which are uniformly distributed are fixedly connected with the outer end of the outer cyclone ball, when a plurality of nodes lead and shake the mixing chain to vibrate, the resilience cyclone ball shakes back and forth in the mixed liquid, when the resilience cyclone ball is in contact collision with the inner wall of the test tube, the elastic soft rods are firstly extruded to generate bending deformation, under the elastic action of the elastic soft rods, the resilience cyclone ball rebounds to shake again, and when the resilience cyclone ball shakes, due to self-shaking and the vibration of the mixed liquid, the outer cyclone ball can do irregular rotary motion around the inner ball, so that the elastic soft rods stir the mixed liquid, thereby through the elasticity of making a round trip of resilience whirlwind ball rock and rotary motion, can realize dual stirring to mixed liquid, further accelerate mixing speed and the effect of mixed liquid.
(5) Still be equipped with the anti-overflow ball between a pair of spacing end ball, seted up circular passageway on the anti-overflow ball, even the rope is located circular passageway's inside, and the anti-overflow ball can realize the shutoff to the test tube open end, makes mixed liquid in vibrations mixing process, is difficult for following the test tube opening part spill.
(6) The diameter of spacing end ball is greater than the aperture of circular passageway, make the displacement range of anti-overflow ball between a pair of spacing end ball, the biggest outer lane diameter of resilience whirlwind ball is less than the aperture of circular passageway, make things convenient for resilience whirlwind ball and even rope to reciprocate in circular passageway is inside, thereby make things convenient for the multinode to draw the extension of shaking the mixing string chain and withdraw, the lower extreme liquid outlet bore of dividing the liquid rifle head is between spacing end ball diameter and anti-overflow ball diameter, spacing end ball can get into the inside of dividing the liquid rifle head, make things convenient for the multinode to draw to shake the mixing string chain and withdraw from the test tube, and, when the multinode draws to shake the mixing string chain and withdraw completely, the anti-overflow ball stops in the liquid outlet department.
(7) The elastic soft rod is made of soft rubber materials, so that the rebound cyclone ball is in contact with the inner wall of the test tube to elastically rebound, and the test tube is not easy to be collided and damaged.
Drawings
Fig. 1 is a perspective view of the present invention;
FIG. 2 is a schematic view of a partial front structure of a multi-node vibration inducing and mixing chain of the present invention;
FIG. 3 is a schematic view of a local front structure at a multi-node vibration inducing and mixing chain of the present invention;
FIG. 4 is a schematic view of the structure at A in FIG. 3;
fig. 5 is a schematic view of a local front structure of the multi-node vibration inducing and mixing string chain of the present invention when in use.
The reference numbers in the figures illustrate:
1 pressurizing rod, 2 built-in pressure pads, 3 reagent bottles, 4 transfer tubes, 5 temporary storage chambers, 6 control panel screens, 7 test tube sensors, 8 joint tubes, 9 liquid separating gun heads, 91 connecting ropes, 92 limiting end balls, 93 rebound cyclone balls, 9301 inner balls, 9302 outer rotary balls, 9303 elastic soft rods, 94 anti-overflow balls, 9401 circular channels, 10 test tube racks, 11 oscillators, 12 lifting devices, 13 handles, 14 timers, 15 indicating lamps, 16 lifting switches, 17 oscillating switches and 18 wire reels.
Detailed Description
The drawings in the embodiments of the present invention will be combined; the technical scheme in the embodiment of the utility model is clearly and completely described; obviously; the described embodiments are only some of the embodiments of the present invention; but not all embodiments, are based on the embodiments of the invention; all other embodiments obtained by a person skilled in the art without making any inventive step; all belong to the protection scope of the utility model.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "top/bottom", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted", "provided", "sleeved/connected", "connected", and the like are to be understood in a broad sense, such as "connected", which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Example (b):
referring to fig. 1, a test specimen pretreatment device comprises a liquid separation device, a timing indicator and a vibration blending device, wherein the liquid separation device comprises a reagent bottle 3 and a temporary storage chamber 5, a transfer tube 4 is connected between the reagent bottle 3 and the temporary storage chamber 5, the upper ends of the reagent bottle 3 and the temporary storage chamber 5 are respectively provided with a socket, two ends of the transfer tube 4 are respectively inserted into a pair of sockets and extend to the inside of the reagent bottle 3 and the temporary storage chamber 5, a sealing structure is formed at the joint of the transfer tube 4 and the socket, the transfer tube 4 and the temporary storage chamber 5 are made of opaque materials, opaque resins such as polystyrene and the like or materials which do not react with reagents can be adopted, a built-in pressure pad 2 is slidably connected inside the reagent bottle 3, the upper end of the built-in pressure pad 2 is fixedly connected with a pressure rod 1, a hemolytic agent is contained inside the reagent bottle 3, the upper liquid level of the hemolytic agent is in contact with the, a seal is formed between the built-in pressure pad 2 and the inner wall of the reagent bottle 3, so that a hemolytic agent can be conveniently extruded into the transfer tube 4, the upper end of the temporary storage chamber 5 is fixedly connected with a control panel 6, the lower end of the temporary storage chamber 5 is fixedly connected with a plurality of evenly distributed joint pipes 8, the lower end of each joint pipe 8 is fixedly connected with a liquid dividing gun head 9, a test tube sensor 7 is fixedly connected onto each joint pipe 8, the vibration and uniform mixing device comprises a processing box connected to the lower end of the temporary storage chamber 5, a detachable structure is arranged between the temporary storage chamber 5 and the processing box and can be installed in a bolt connection mode, the joint pipes 8 penetrate through the upper end of the processing box and extend into the processing box, the processing box is internally divided into a plurality of dark chambers through partition plates, the whole box is made of light-tight materials, the light-tight materials are not limited, the light-tight materials of the box body, thickness is formulated according to the laboratory demand, the darkroom number is customized according to the laboratory demand, the darkroom can be used for storing the sample test tube, reduce the extra condition of building the darkroom of increasing the cost, the inside of handling the case is equipped with a plurality of oscillators 11, the number of oscillator 11 and darkroom is the same and the one-to-one, the same evenly distributed of a plurality of joint pipes 8 is inside a plurality of darkrooms, the elevating gear 12 of a plurality of evenly distributed of lower extreme fixedly connected with of oscillator 11, test-tube rack 10 has been placed to oscillator 11's upper end, the buckle of a plurality of and test-tube rack 10 joints of upper end fixedly connected with of oscillator 11, the vibration amplitude difference degree of oscillator 11 can be adjusted according to the demand, the direction of vibration can be around or about, the inside of dividing pipette head 9 is equipped with the multinode and draws the even mixing chain of shaking.
The timing indicating device comprises a plurality of darkroom doors which are rotatably connected with the outer end of the treatment box, the plurality of darkroom doors correspond to the plurality of darkroom doors one by one, the outer end of the darkroom door is fixedly connected with a handle 13, a timer 14, an indicating lamp 15, a lifting switch 16 and a vibrating switch 17, the test tube inductor 7, the timer 14 and the indicating lamp 15 are all electrically connected with the control panel 6, the oscillator 11 is electrically connected with the lifting switch 16, the oscillator 11 can be started by pressing the lifting switch 16, the lifting device 12 is electrically connected with the vibrating switch 17, the lifting device 12 can be started by pressing the vibrating switch 17, when the timer 14 starts (the indicator light 15 changes to red or other colors, the color can be set through the control panel 6, and the daily non-use state is not bright), the indicator light 15 changes to green or other colors at regular time, and the staff can timely carry out the next step according to the color change.
Referring to fig. 2 and 3, the multi-node vibration-inducing mixing string chain includes a connecting rope 91 inside the liquid-separating gun head 9, a pair of limiting end balls 92 and a plurality of resilient cyclone balls 93 are fixedly connected to the connecting rope 91, the resilient cyclone balls 93 are uniformly distributed between the limiting end balls 92, a plurality of reels 18 are fixedly connected to the inner top end of the temporary storage chamber 5, the upper end of the connecting rope 91 penetrates through the inside of the joint pipe 8 until the upper end of the reels is fixedly connected to the outer end of the reels 18, the reels 18 are electrically connected to the control panel 6, during liquid separation, the multi-node vibration-inducing mixing string chain extends downwards to the corresponding test tube and enters the mixed liquid, when the test tube of the oscillator 11 is started to vibrate, the multi-node vibration inducing and mixing chain is contacted with the inner wall of the test tube to realize the transmission of vibration, the multi-node vibration inducing and mixing string chain vibrates in the mixed liquid and collides with the mixed liquid, so that the mixing effect of the mixed liquid can be further enhanced.
Referring to fig. 4 and 5, the resilient cyclone ball 93 includes an inner ball 9301 fixedly connected to an outer end of a connecting rope 91, an outer cyclone ball 9302 is disposed outside the inner ball 9301, a ball groove is disposed inside the outer cyclone ball 9302, wire holes are disposed on upper and lower inner walls of the ball groove, the inner ball 9301 is rotatably connected to the ball groove, the connecting rope 91 is disposed inside the wire holes, a plurality of elastic soft rods 9303 are fixedly connected to an outer end of the outer cyclone ball 9302, when a multi-node vibration induced mixing chain is vibrated, the resilient cyclone ball 93 rocks back and forth in a mixed liquid, when the resilient cyclone ball 93 collides with an inner wall of a test tube, the elastic soft rods 9303 are squeezed to generate bending deformation, and the resilient cyclone ball 93 rebounds under an elastic action of the elastic soft rods 9303 to perform a secondary rocking motion, and when the resilient cyclone ball 93 rocks, the outer cyclone ball 9302 performs a random rotation motion around the inner ball 9301 due to its own rocking and the vibration of the mixed liquid, make the soft stick of elasticity 9303 stir mixed liquid again to rock and rotary motion through the elasticity of making a round trip of resilience whirlwind ball 93, can realize dual stirring to mixed liquid, further accelerate mixing speed and the effect of mixed liquid, the soft stick of elasticity 9303 adopts soft rubber materials to make, when making resilience whirlwind ball 93 and test tube inner wall contact carry out the elasticity resilience, be difficult for causing collision damage to the test tube.
An anti-overflow ball 94 is further arranged between the pair of limiting end balls 92, a circular channel 9401 is formed in the anti-overflow ball 94, the connecting rope 91 is located inside the circular channel 9401, the anti-overflow ball 94 can seal the opening end of a test tube, mixed liquid is not prone to splashing from the opening of the test tube in the vibration mixing process, the diameter of the limiting end ball 92 is larger than the aperture of the circular channel 9401, the moving range of the anti-overflow ball 94 is located between the pair of limiting end balls 92, the maximum outer ring diameter of the rebound cyclone ball 93 is smaller than the aperture of the circular channel 9401, the rebound cyclone ball 93 and the connecting rope 91 can conveniently move up and down inside the circular channel 9401, accordingly, extension and recovery of a multi-node induced-vibration mixing string chain are facilitated, the aperture of a liquid outlet at the lower end of the liquid separating gun head 9 is located between the diameter of the limiting end ball 92 and the diameter of the anti-overflow ball 94, the limiting end ball 92 can enter, and when the multi-node induced vibration mixing string chain is completely retracted, the anti-overflow ball 94 stays at the liquid outlet of the liquid separating gun head 9.
The utility model discloses can deposit and regularly in order black space to the whole sample mixed liquid that adds sample and reagent in batches, and realize the quantitative application of sample of same kind in batches, improve and divide liquid efficiency, still assist the mixing to multiple mixed liquid after the liquid feeding simultaneously, mixed liquid reaction efficiency has been improved greatly, guarantee the accuracy of inspection result, change the series operation in traditional manual operation into mechanical parallel operation, save operating time, avoid endangering staff's personal safety simultaneously, the device not only can be applicable to the aspect of flow cytometry, do use and other needs add same kind of reagent of equivalent in batches. Meanwhile, the problem that the samples after being added with samples are stored in different places can be solved, personnel need to spend energy in different places to find the samples for further processing, or extra cost is increased in a laboratory to build a darkroom, and the laboratory effective space can be utilized by using the whole device.
The above; is only a preferred embodiment of the present invention; however, the scope of protection of the present invention is not limited thereto; any person skilled in the art is within the technical scope of the present disclosure; according to the technical scheme of the utility model and the improvement conception, equivalent substitution or change is carried out; are all covered by the protection scope of the utility model.

Claims (7)

1. The utility model provides an inspection sample preprocessing device, is including dividing liquid device, timing indicating device and shaking mixing device, its characterized in that: the liquid separating device comprises a reagent bottle (3) and a temporary storage chamber (5), a transfer pipe (4) is connected between the reagent bottle (3) and the temporary storage chamber (5), two ends of the transfer pipe (4) respectively extend to the inside of the reagent bottle (3) and the temporary storage chamber (5), a built-in pressure pad (2) is connected in a sliding mode inside the reagent bottle (3), a pressure rod (1) is fixedly connected to the upper end of the built-in pressure pad (2), a hemolytic agent is contained inside the reagent bottle (3), the upper liquid level of the hemolytic agent is in contact with the lower bottom face of the built-in pressure pad (2), a control panel (6) is fixedly connected to the upper end of the temporary storage chamber (5), a plurality of uniformly distributed joint pipes (8) are fixedly connected to the lower end of the joint pipe (8), a liquid separating gun head (9) is fixedly connected to the lower end of the joint pipe (8), and a test tube inductor (7) is fixedly connected to the joint pipe (8), vibrate mixing device including connecting in the processing case of room (5) lower extreme of keeping in, joint pipe (8) run through the upper end of handling the case and extend to the inside of handling the case, the inside of handling the case is equipped with a plurality of oscillators (11), elevating gear (12) of a plurality of evenly distributed of lower extreme fixedly connected with of oscillator (11), test-tube rack (10) have been placed to the upper end of oscillator (11), the upper end fixedly connected with of oscillator (11) a plurality of buckles with test-tube rack (10) joint, the inside of dividing liquid rifle head (9) is equipped with the multinode and draws and shakes the mixing cluster chain.
2. The test specimen pretreatment device according to claim 1, characterized in that: timing indicating device includes that a plurality of rotations connect in the darkroom door of handling the case outer end, the outer end fixedly connected with handle (13), timer (14), pilot lamp (15), lifting switch (16) and shock switch (17) of darkroom door, test tube inductor (7), timer (14) and pilot lamp (15) all with control panel screen (6) electric connection, oscillator (11) and lifting switch (16) electric connection, elevating gear (12) and shock switch (17) electric connection.
3. The test specimen pretreatment device according to claim 1, characterized in that: the multinode is drawn and is shaken mixing cluster chain is including being located the inside company rope (91) of liquid separating gun head (9), it goes up a pair of spacing end ball (92) of fixedly connected with and a plurality of resilience whirlwind ball (93) to link rope (91), and is a plurality of resilience whirlwind ball (93) evenly distributed is between a pair of spacing end ball (92), the interior top end fixedly connected with a plurality of winder (18) of room (5) of keeping in, the outer end fixed connection of inside until and winder (18) of the upper end run-through joint pipe (8) of rope (91), winder (18) and control panel screen (6) electric connection.
4. The test specimen pretreatment device according to claim 3, characterized in that: resilience whirlwind ball (93) are including fixed connection in interior ball (9301) even rope (91) outer end, the outside of interior ball (9301) is equipped with outer ball (9302) of revolving, the ball groove has been seted up to the inside of outer ball (9302) of revolving, the line hole has all been seted up to the upper and lower inner wall in ball groove, interior ball (9301) rotates and connects in the inside of ball groove, even rope (91) are located the inside in line hole, the outer end fixedly connected with a plurality of evenly distributed's of ball (9302) of revolving elasticity soft stick (9303).
5. The test specimen pretreatment device according to claim 3, characterized in that: an anti-overflow ball (94) is further arranged between the pair of limiting end balls (92), a circular channel (9401) is formed in the anti-overflow ball (94), and the connecting rope (91) is located inside the circular channel (9401).
6. The test specimen pretreatment device according to claim 5, characterized in that: the diameter of the limiting end ball (92) is larger than the aperture of the circular channel (9401), the maximum outer ring diameter of the rebound cyclone ball (93) is smaller than the aperture of the circular channel (9401), and the aperture of a liquid outlet at the lower end of the liquid separation gun head (9) is between the diameter of the limiting end ball (92) and the diameter of the anti-overflow ball (94).
7. The test specimen pretreatment device according to claim 4, characterized in that: the elastic soft rod (9303) is made of soft rubber materials.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111889002A (en) * 2020-08-25 2020-11-06 郑州金域临床检验中心有限公司 Test specimen pretreatment device and use method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111889002A (en) * 2020-08-25 2020-11-06 郑州金域临床检验中心有限公司 Test specimen pretreatment device and use method thereof

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