CN212369424U - Implanted nerve stimulator with temperature measurement function and system - Google Patents
Implanted nerve stimulator with temperature measurement function and system Download PDFInfo
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- CN212369424U CN212369424U CN202020449036.9U CN202020449036U CN212369424U CN 212369424 U CN212369424 U CN 212369424U CN 202020449036 U CN202020449036 U CN 202020449036U CN 212369424 U CN212369424 U CN 212369424U
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Abstract
The utility model provides an implanted neural stimulator and system with temperature measurement function, the stimulator includes: a stimulation contact for releasing a stimulation signal to a deep brain target; the temperature measuring component is used for measuring the temperature near the brain deep target point; the temperature acquisition circuit and the pulse output circuit are arranged in the shell with biocompatibility, the pulse output circuit is used for outputting stimulation signals and is connected with the stimulation contact through a lead, and the temperature acquisition circuit is connected with the temperature measurement component through a lead and is used for receiving temperature signals measured by the temperature acquisition circuit. The embodiment of the utility model provides an implanted neural stimulator when providing the electro photoluminescence treatment function through pulse output circuit and amazing contact, can also realize the long-term measurement of amazing target point position temperature through temperature measurement part and temperature acquisition circuit, has important value to the mechanism research of deep electro photoluminescence therapy of brain and the research of other brain functions.
Description
Technical Field
The utility model relates to an electron medical equipment field, concretely relates to implanted neural stimulator and system with temperature measurement function.
Background
The brain accounts for only 2% of the body's mass, but 25% of the body's total glucose utilization and 20% of oxygen consumption, it is a metabolic organ with intense heat generation, almost all brain processes are sensitive to temperature fluctuations, its energy consumption efficiency is highly dependent on temperature, and the thermal regulation capacity of the brain may define its anatomical and physiological structure and limit its processing capacity. Measurement of deep brain temperature is of great research significance, and related research reports on brain heat genetic therapy are also reported in recent years.
The prior art proposes that the nuclear magnetic resonance technology can be used for measuring the internal temperature of the brain, but the measurement mode needs large-scale equipment, has high cost and poor convenience, and cannot realize long-term monitoring.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model provides an implanted neural stimulator with temperature measurement function, include:
a stimulation contact for releasing a stimulation signal to a deep brain target;
the temperature measuring component is used for measuring the temperature near the brain deep target point;
the temperature acquisition circuit and the pulse output circuit are arranged in the shell with biocompatibility, the pulse output circuit is used for outputting stimulation signals and is connected with the stimulation contact through a lead, and the temperature acquisition circuit is connected with the temperature measurement component through a lead and is used for receiving temperature signals measured by the temperature acquisition circuit.
Optionally, the stimulator further comprises:
a temperature control component for changing the temperature near the deep brain target;
and the temperature control circuit is arranged in the shell, is connected with the temperature control component through a lead and is used for outputting a temperature control signal so as to change the temperature of the temperature control component.
Optionally, the stimulation contacts are distributed on one side of the electrode catheter, and the temperature measuring component is arranged at the end part of the electrode catheter on the side where the stimulation contacts are located.
Optionally, a connection point for connecting the stimulation contact and a connection point for connecting the temperature measurement component are distributed on the other side of the electrode catheter, and the lead is arranged in the electrode catheter.
Optionally, the stimulation contacts are distributed on one side of the electrode catheter, and the temperature control component is arranged at the end part of the electrode catheter on the side where the stimulation contacts are located.
Optionally, a connection point for connecting the stimulation contact and a connection point for connecting the temperature control component are distributed on the other side of the electrode catheter, and the lead is arranged in the electrode catheter.
Optionally, the stimulator is further provided with a temperature storage unit, disposed in the casing, for recording the temperature value acquired by the temperature acquisition circuit.
Optionally, the stimulator is further provided with a communication unit, configured to send a temperature value corresponding to the temperature signal to an extracorporeal control device.
Optionally, the stimulator is further provided with a communication unit for receiving data sent by the extracorporeal control device for setting the temperature control circuit.
Optionally, the temperature measuring component is an NTC thermistor.
Optionally, the temperature control component comprises a heating component and/or a cooling component.
The utility model also provides an implanted neural stimulation system with temperature measurement function, including above-mentioned implanted neural stimulator and external controlgear for acquire brain deep temperature.
The embodiment of the utility model provides an implanted neural stimulator and system when providing the electro photoluminescence treatment function through pulse output circuit and amazing contact, can also realize the long-term measurement of amazing target point position temperature through temperature measurement part and temperature acquisition circuit, have important value to the mechanism research of brain deep electro photoluminescence therapy and the research of other brain functions.
The embodiment of the utility model provides an implanted neural stimulator and system can also realize the regulation to the deep temperature of brain through accuse temperature part and temperature control circuit, can further assist the influence of field technical personnel research temperature to brain function.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the technical solutions in the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a circuit diagram of an implantable neurostimulator in an embodiment of the present invention;
fig. 2 is a schematic structural diagram of an implantable neurostimulator in an embodiment of the present invention;
fig. 3 is a schematic structural view of an electrode catheter according to an embodiment of the present invention;
fig. 4 is a schematic structural view of a housing and a top cover of the stimulator in an embodiment of the present invention;
fig. 5 is a circuit diagram of another implantable neurostimulator in an embodiment of the present invention;
fig. 6 is a circuit diagram of a third implantable neurostimulator in an embodiment of the present invention;
fig. 7 is a schematic structural view of another electrode catheter in an embodiment of the present invention;
fig. 8 is a schematic structural diagram of an implantable neurostimulation system according to an embodiment of the present invention.
Detailed Description
The technical solution of the present invention will be described clearly and completely with reference to the accompanying drawings, and obviously, the described embodiments are some, but not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Furthermore, the technical features mentioned in the different embodiments of the invention described below can be combined with each other as long as they do not conflict with each other.
The implantable neurostimulator is widely applied to the treatment of various neurodegenerative diseases, such as a cerebral pacemaker, a spinal cord stimulator, a sacral neurostimulator and the like, and the working principle of the implantable neurostimulator is that an electrical stimulation signal is generated through a pulse generator implanted in a body, and the electrical stimulation signal is transmitted to a corresponding stimulation target through an extension lead and an electrode implanted in the body under the skin to stimulate the stimulation target so as to treat related diseases.
The embodiment of the utility model provides an implanted neural stimulator with temperature measurement function, this stimulator includes a plurality of stimulation contacts 11, a plurality of temperature measurement parts 12, temperature acquisition circuit 13 and pulse output circuit 14 as shown in figure 1.
The stimulation contacts 11 are used to deliver stimulation signals to deep brain targets. In actual use, the target position is determined according to requirements, for example, the position of a deep brain nucleus.
The thermometric component 12 is used to measure the temperature near the target site deep in the brain, with its sensing location close to the location of the stimulating contact 11. The Temperature measuring part 12 may be a thermocouple, an NTC (Negative Temperature Coefficient) thermistor, or the like.
As shown in fig. 2, the temperature acquisition circuit 13 and the pulse output circuit 14 are disposed in a biocompatible housing 20, and the pulse output circuit 14 is used for outputting a stimulation signal, and is connected to the stimulation contact 11 through a lead, so that the stimulation signal acts on an implantation target; the temperature acquisition circuit 13 is connected with the temperature measurement component 12 through a lead wire and is used for receiving the temperature signal measured by the temperature acquisition circuit.
For convenient and accurate implantation of the stimulating contacts 11 and the thermometric component 12, the present embodiment provides both components integrally. As shown particularly in fig. 3, the stimulator typically has a plurality of channels, each channel having a plurality of stimulation contacts, the contacts of the same channel being distributed on one side of the electrode catheter 30, in this embodiment four stimulation contacts 11 are shown, and may be eight or sixteen stimulation contacts.
The side on which the stimulation contacts are located is commonly referred to in the art as the stimulation end, and the other end of the electrode catheter 30 is used to connect to the circuitry within the housing 20, and is therefore referred to as the connection end. The thermometric component 12 may be one or more and may be located anywhere within the electrode catheter 30, such as near the stimulating end or near the connecting end, or both. In order to measure the brain deep temperature, only one thermometric member 12 is provided in the present embodiment, and is provided at the end of the electrode catheter 30 on the side where the stimulation contact 11 is located, that is, the end of the stimulation tip.
The other side of the electrode conduit 30, i.e. the connecting end, is distributed with a connecting point 31 for connecting the stimulating contact 11 and the temperature measuring component 12, the lead is arranged in the electrode conduit 30, and the stimulating contact 11 and the temperature measuring component 12 are respectively connected with the corresponding connecting point 31 through the lead.
As shown in fig. 4, the case 20 includes a top cover 201, the metal connecting member 41 is disposed in the top cover 201 for connecting with the connecting point 31, and the metal connecting member 41 in the top cover 201 is connected with the circuit inside the case 20 through the feed-through connector, thereby connecting the stimulating contact 11 and the temperature measuring part 12 with the corresponding contacts in the circuit.
As shown in fig. 5, the implantable neurostimulator may further be provided with a temperature storage unit 51 and a communication unit 52, which are also provided in the housing 20. The communication unit 52 is configured to send the temperature value corresponding to the temperature signal to the extracorporeal control apparatus, and the communication mode adopted by the communication unit may be near field coupling communication, radio frequency communication, bluetooth communication, or the like. The temperature storage unit 51 is used for recording the temperature value acquired by the temperature acquisition circuit, so that the stimulator can measure and store the temperature value for a long time without intervention of an external control device, and transmit the stored deep brain temperature value within a certain time to the external control device when needed.
The embodiment of the utility model provides an implanted neural stimulator when providing the electro photoluminescence treatment function through pulse output circuit and amazing contact, can also realize the long-term measurement of amazing target point position temperature through temperature measurement part and temperature acquisition circuit, has important value to the mechanism research of deep electro photoluminescence therapy of brain and the research of other brain functions.
The embodiment of the utility model provides an implanted neural stimulator with temperature measurement function, this stimulator includes a plurality of amazing contacts 11, a plurality of temperature measurement part 12, a plurality of accuse temperature part 15, temperature acquisition circuit 13, pulse output circuit 14 and temperature control circuit 16 as shown in fig. 6.
The stimulation contact 11 is used for releasing a stimulation signal to a deep brain target point; the temperature measuring component 12 is used for measuring the temperature near the deep brain target point; the temperature control component 15 is used for changing the temperature near the brain deep target point, the temperature control component 15 influences the temperature near the brain deep target point by changing the temperature of the temperature control component, and the position of the temperature control component 15 is close to the position of the stimulating contact 11, and the temperature control component can be a heating resistor, a semiconductor heating or refrigerating element and the like.
The temperature acquisition circuit 13, the temperature control circuit 16 and the pulse output circuit 14 are arranged in a biocompatible shell, and the pulse output circuit 14 is used for outputting a stimulation signal and is connected with the stimulation contact 11 through a lead so that the stimulation signal acts on an implantation target spot; the temperature acquisition circuit 13 is connected with the temperature measurement component 12 through a lead wire and is used for receiving a temperature signal measured by the temperature acquisition circuit; the temperature control circuit 16 is connected to the temperature control member 15 through a lead wire, and is configured to output a temperature control signal to change the temperature of the temperature control member 15. The temperature control circuit 16 can realize the electrical control of the temperature control component 15 and comprises a protection circuit to ensure that the temperature is adjusted within a safe range.
In order to implant the stimulating contact 11, the temperature measuring part 12 and the temperature controlling part 15 conveniently and accurately, the three parts are integrally provided in the present embodiment. As shown in particular in fig. 7, a plurality of stimulation contacts 11 are distributed on one side (stimulation end) of the electrode catheter 30. One or more temperature measuring parts 12 and temperature control parts 15 can be provided, respectively, and can be arranged at any position in the electrode catheter 30, such as near the stimulation end or near the connection end, or between the two. In order to measure the brain deep temperature, only one temperature measuring part 12 and one temperature control part 15 are provided in the present embodiment, and are provided at the end portion of the electrode catheter 30 on the side where the stimulation contact 11 is located, that is, the end portion of the stimulation tip.
The other side of the electrode conduit 30, namely the connecting end, is distributed with a connecting point 31 for connecting the stimulating contact 11, the temperature measuring component 12 and the temperature controlling component 15, the leading wire is arranged in the electrode conduit 30, and the stimulating contact 11, the temperature measuring component 12 and the temperature controlling component 15 are respectively connected with the corresponding connecting point 31 through the leading wire. Correspondingly, a metal connecting piece for connecting the stimulating contact, a metal connecting piece for connecting the temperature measuring part and a metal connecting piece for connecting the temperature controlling part are arranged in the top cover of the shell, and the metal connecting piece in the top cover is connected with a circuit in the shell through a feed-through connector, so that the stimulating contact 11, the temperature measuring part 12 and the temperature controlling part 15 are connected with corresponding contacts in the circuit.
The implantable neural stimulator of the present embodiment is further provided with a temperature storage unit 51 and a communication unit 52, which are also provided in the housing. The temperature storage unit 51 is used for recording the temperature value acquired by the temperature acquisition circuit, the communication unit 52 is used for sending the temperature value corresponding to the temperature signal to the external control equipment and receiving the data sent by the external control equipment and used for setting the temperature control circuit, and the user can set the temperature of the temperature control part 15 through the external control device.
The embodiment of the utility model provides an implanted neural stimulator when providing the electro photoluminescence treatment function through pulse output circuit and amazing contact, can also realize the long-term measurement of amazing target point position temperature through temperature measurement part and temperature acquisition circuit to can realize the regulation to brain deep temperature through accuse temperature part and temperature control circuit, can further study the influence of temperature to brain function, the mechanism research and other brain function's research to brain deep electro photoluminescence therapy have important value.
As shown in fig. 8, an implantable neurostimulation system with temperature measurement function according to the embodiment of the present invention includes an implantable neurostimulator 81 shown in fig. 1 or fig. 6 and an external control device 82. The extracorporeal control device 82 is a device having an interactive component and a display screen, and may be a dedicated device or a general electronic device such as a smart phone or a tablet computer, and performs data interaction with the stimulator inside the body in a wireless communication manner. For a system with only temperature measurement components, the in vitro control device 82 is used to obtain the deep brain temperature; for systems with temperature measurement and temperature control components, the in vitro control device 82 can obtain the brain core temperature and set the temperature of the temperature control component, i.e., regulate the brain core temperature.
As will be appreciated by one skilled in the art, embodiments of the present invention may be provided as a method, system, or computer program product. Accordingly, the present invention may take the form of an entirely hardware embodiment, an entirely software embodiment or an embodiment combining software and hardware aspects. Furthermore, the present invention may take the form of a computer program product embodied on one or more computer-usable storage media (including, but not limited to, disk storage, CD-ROM, optical storage, and the like) having computer-usable program code embodied therein.
The present invention has been described with reference to flowchart illustrations and/or block diagrams of methods, apparatus (systems) and computer program products according to embodiments of the invention. It will be understood that each flow and/or block of the flow diagrams and/or block diagrams, and combinations of flows and/or blocks in the flow diagrams and/or block diagrams, can be implemented by computer program instructions. These computer program instructions may be provided to a processor of a general purpose computer, special purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, create means for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including instruction means which implement the function specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications can be made without departing from the scope of the invention.
Claims (10)
1. An implantable neural stimulator with temperature measurement, comprising:
a stimulation contact for releasing a stimulation signal to a deep brain target;
the temperature measuring component is used for measuring the temperature near the brain deep target point;
the temperature acquisition circuit and the pulse output circuit are arranged in the shell with biocompatibility, the pulse output circuit is used for outputting stimulation signals and is connected with the stimulation contact through a lead, and the temperature acquisition circuit is connected with the temperature measurement component through a lead and is used for receiving temperature signals measured by the temperature acquisition circuit.
2. The implantable neural stimulator of claim 1, further comprising:
a temperature control component for changing the temperature near the deep brain target;
and the temperature control circuit is arranged in the shell, is connected with the temperature control component through a lead and is used for outputting a temperature control signal so as to change the temperature of the temperature control component.
3. The implantable neural stimulator of claim 1, wherein the stimulation contacts are distributed on one side of the electrode catheter, and the temperature measurement component is disposed at an end of the electrode catheter on the side where the stimulation contacts are located;
the other side of the electrode catheter is provided with a connecting point used for connecting the stimulating contact and a connecting point used for connecting the temperature measuring component, and the lead is arranged in the electrode catheter.
4. The implantable neural stimulator of claim 2, wherein the stimulation contacts are disposed on one side of the electrode catheter, and the temperature control member is disposed at an end portion of the electrode catheter on the side of the stimulation contacts;
the other side of the electrode catheter is provided with a connecting point used for connecting the stimulating contact and a connecting point used for connecting the temperature control component, and the lead is arranged in the electrode catheter.
5. The implantable neural stimulator of claim 1, further comprising a temperature storage unit disposed within the housing for recording temperature values collected by the temperature collection circuit.
6. The implantable neural stimulator of claim 1, further comprising a communication unit configured to send a temperature value corresponding to the temperature signal to an external control device.
7. The implantable neurostimulator of claim 2, further comprising a communication unit for receiving data sent by an external control device for setting the temperature control circuit.
8. The implantable neural stimulator of claim 1, wherein the temperature measurement component is an NTC thermistor.
9. The implantable neural stimulator of claim 2, wherein the temperature control component comprises a heating component and/or a cooling component.
10. An implantable neurostimulation system with temperature measurement capability, comprising:
an implantable neurostimulator as claimed in any one of claims 1 to 9 together with an in vitro control device for obtaining deep brain temperature.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020449036.9U CN212369424U (en) | 2020-03-31 | 2020-03-31 | Implanted nerve stimulator with temperature measurement function and system |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202020449036.9U CN212369424U (en) | 2020-03-31 | 2020-03-31 | Implanted nerve stimulator with temperature measurement function and system |
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| Publication Number | Publication Date |
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| CN212369424U true CN212369424U (en) | 2021-01-19 |
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| CN202020449036.9U Active CN212369424U (en) | 2020-03-31 | 2020-03-31 | Implanted nerve stimulator with temperature measurement function and system |
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