CN212288766U

CN212288766U - High-temperature 3D biological printing nozzle

Info

Publication number: CN212288766U
Application number: CN202020420071.8U
Authority: CN
Inventors: 郭如瀚; 齐志林; 周铁兵
Original assignee: Shangpu Beijing Biotechnology Co ltd
Current assignee: Shangpu Beijing Biotechnology Co ltd
Priority date: 2020-03-27
Filing date: 2020-03-27
Publication date: 2021-01-05
Anticipated expiration: 2030-03-27

Abstract

The utility model relates to a high temperature 3D prints shower nozzle biologically, can print polymer granular material, including shower nozzle main part, shower nozzle base, radiation shield and heating element, the shower nozzle main part sets up on the shower nozzle base, the downside of shower nozzle base is connected with the radiation shield, be provided with the feed bin in the radiation shield, heating element sets up in the radiation shield or on the lower surface of radiation shield, heating element is including extruding the pipeline and right extrude the heating device of pipeline heating, the first end of feed bin in the radiation shield with heating element's the first end intercommunication of extruding the pipeline. The embodiment of the utility model provides a high temperature 3D prints shower nozzle biologically has thermal-insulated design, can reduce the scald risk that probably appears, prevents to the high temperature damage of other devices, can print graininess macromolecular material, allows to mix the material powder that improves intensity or biocompatibility in macromolecular material.

Description

High-temperature 3D biological printing nozzle

Technical Field

The utility model belongs to the technical field of 3D is biological to be printed, concretely relates to high temperature 3D prints shower nozzle biologically.

Background

The 3D biological printer can be driven by a digital three-dimensional model, and can be used for positioning and assembling biological materials or cell units according to the additive manufacturing principle to manufacture products such as medical instruments, tissue engineering scaffolds, tissue organs and the like. The 3D biological printer can include a plurality of shower nozzles of printing, has placed the syringe inside printing the shower nozzle, has held biological ink in the syringe, and the syringe extrudes biological ink on print platform through the syringe needle for print the shower nozzle and can print out human cell and/or biomaterial, the 3D biological printer prints through the motion of control printing shower nozzle.

The biological material for printing mainly comprises a high polymer material and a hydrogel material, wherein the high polymer material can provide excellent mechanical support and biocompatibility and can be degraded. However, the polymer material is often required to be melted from a solid to a liquid at a relatively high temperature (100-.

At present, there are two main 3D printing schemes for printing polymer materials.

One is a 3D printing scheme using hot melt extrusion (FDM), which is a commonly used process for common 3D printers, and is to heat and melt a polymer wire, extrude the polymer wire through a nozzle, and stack the polymer wire into a product with a certain shape on a workbench. However, the method for printing the high molecular biological material by using the hot melt extrusion technology has the defects that the degradable high molecular material which can be transplanted to a human body is granular solid, the FDM process does not support the melt extrusion of the granular solid, the FDM process needs to use wire materials, and in the process of processing the high molecular material into the wire materials from granules, the processing technology is increased, and the requirement on cleanliness cannot be met; meanwhile, the polymer materials used in 3D bioprinting often need to be mixed with inorganic powders for increasing the strength of the stent or biocompatibility, and the FDM process cannot add these powders. Therefore, the FDM process is not suitable for bioprinting of high molecular materials.

The other method is to adopt a metal injector, load a high polymer material to heat and melt for extrusion printing, and although granular high polymer materials can be printed, the metal injector cannot insulate heat and is easy to scald; moreover, the metal injector can accelerate heat conduction, so that the operation of other devices of the spray head is seriously influenced, particularly electronic components such as an electric connector, a motor and the like are seriously influenced, and the devices are damaged due to high temperature; in addition, the consumption condition of the printing material can not be observed by the metal injector, the consumption condition can only be estimated, the printing interruption can be caused, the high-temperature metal injector can not be fed in time, the feeding can only be carried out after the cooling, and the printing effect is influenced.

SUMMERY OF THE UTILITY MODEL

In order to solve the technical problem, the utility model provides a can print biological shower nozzle of printing of high temperature 3D of granular material, including shower nozzle main part, shower nozzle base, radiation shield and heating element, the shower nozzle main part sets up on the shower nozzle base, the downside of shower nozzle base is connected with the radiation shield, be provided with the feed bin in the radiation shield, heating element sets up in the radiation shield or on the lower surface of radiation shield, heating element is including extruding the pipeline and right extrude the heating device of pipeline heating, the first end of the feed bin in the radiation shield with heating element's the first end intercommunication of extruding the pipeline.

Further, a bin in the heat insulation sleeve is provided with a hollow cylindrical space, two ends of the bin are opened, and the bin penetrates from the lower surface of the heat insulation sleeve to the upper surface of the heat insulation sleeve.

Further, the middle part of feed bin with first end sets up in the radiation shield main part, the second end of feed bin is followed the upper surface of radiation shield main part and is outwards stretched out.

Furthermore, the side wall of the heat insulation sleeve is provided with a material hole which is communicated with the storage bin in a straight line and can be sealed by a transparent hole plug.

Further, the heating assembly is integrally formed by a metal material, and/or the heat insulation sleeve is integrally formed by a polyether-ether-ketone material.

Further, the extrusion pipeline is in a hollow column shape, the heating device is in a plate shape, the extrusion pipeline penetrates through the heating device, and the heating device is at least connected to the middle of the extrusion pipeline.

Further, the first end of the extrusion line extends outward from the upper surface of the heating device and is inserted into the first end of the cartridge.

Further, a convex structure is arranged on a contact surface between the heating assembly and the heat insulation sleeve.

Further, the heating assembly is embedded into the lower surface of the heat insulation sleeve, and a protruding structure is arranged on the lower surface of the position, embedded into the heating assembly, of the heat insulation sleeve.

Further, the heat insulation sleeve also comprises an air inlet hole, the air inlet hole penetrates from the lower surface of the heat insulation sleeve to the upper surface of the heat insulation sleeve, a heat dissipation fan is installed at the air inlet hole, and the heat dissipation fan introduces external air flow into the spray head; the shower nozzle comprises a shower nozzle base and is characterized in that a connecting through hole penetrating through the upper surface and the lower surface of the shower nozzle base is formed in the shower nozzle base, a shower nozzle main body is installed on the connecting through hole in the upper surface of the shower nozzle base, a heat insulation sleeve is installed on the lower side of the shower nozzle base, and the connecting through hole in the shower nozzle base is opposite to an air inlet hole of the heat insulation sleeve.

Furthermore, a transmission rod hole penetrating through the upper surface and the lower surface of the spray head base is formed in the spray head base, the transmission rod hole is aligned with the columnar space of the storage bin of the heat insulation sleeve, a transmission rod is placed in the transmission rod hole, and the lower end portion of the transmission rod can be inserted into the storage bin.

Further, the second end of the storage bin extends out of the upper surface of the heat insulation sleeve main body and is hermetically inserted into the transmission rod hole of the spray head base.

Furthermore, the transmission rod is a push rod, and the lower end part of the push rod is in a shape matched with the inner wall of the storage bin; or the transmission rod is a screw rod.

Furthermore, be provided with control chip, motor and push rod clamp plate on the shower nozzle main part, the push rod clamp plate is connected with the top of push rod, and control chip can drive motor and drive push rod clamp plate and push rod and reciprocate.

The utility model has the advantages that: the embodiment of the utility model provides a high temperature 3D prints shower nozzle biologically has thermal-insulated design, can reduce the scald risk that probably appears, prevents to the high temperature damage of other devices, can print graininess macromolecular material, allows to mix the material powder that improves intensity or biocompatibility in macromolecular material.

The utility model discloses in the further scheme that provides, can carry out the feed bin and observe and feed in real time.

Drawings

Fig. 1 is an assembly view of the components of a high temperature 3D bioprinting nozzle according to an embodiment of the present invention;

fig. 2 is a perspective view of a thermal sleeve of a high temperature 3D bioprinting nozzle in accordance with an embodiment of the present invention;

fig. 3 is a bottom side view of a thermal sleeve of a high temperature 3D bioprinting head in accordance with an embodiment of the present invention;

fig. 4 is an assembly structure diagram of a heat insulation sleeve and a heating assembly of the high-temperature 3D bio-printing nozzle according to the embodiment of the present invention;

fig. 5 is an assembly structure view of the push rod assembly of the high-temperature 3D bio-printing nozzle according to the embodiment of the present invention.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in detail with reference to the accompanying drawings. Those skilled in the art will appreciate that the present invention is not limited to the drawings and the following embodiments.

As used herein, the term "include" and its various variants are to be understood as open-ended terms, which mean "including, but not limited to. The terms "upper", "lower" and the like are used only to indicate a positional relationship between relative objects. Term(s) for

The terms "first", "second" and the like are used merely to indicate different technical features, and have no essential meaning.

The embodiment of the utility model provides a high temperature 3D prints shower nozzle biologically, can print polymer granular material as shown in fig. 1-5, including shower nozzle main part 1, shower nozzle base 3, radiation shield 4 and heating element 6, shower nozzle main part 1 sets up on the shower nozzle base 3, shower nozzle base 3's downside is connected with radiation shield 4, be provided with feed bin 41 in the radiation shield 4, heating element 6 sets up in the radiation shield 4 or on the lower surface of radiation shield 4, heating element 6 is including extruding pipeline 61 and right extrude the heating device 62 of pipeline 61 heating, the first end of feed bin 41 in the radiation shield 4 with the first end intercommunication of heating element 6's the pipeline of extruding.

The bin 41 of the heat insulating sleeve 4 has a hollow cylindrical space, preferably, a cylindrical shape, and both ends of the bin 41 are open and penetrate from the lower surface of the heat insulating sleeve 4 to the upper surface of the heat insulating sleeve 4. The middle and first ends of the bin 41 are disposed in the insulation jacket main body, and the second end of the bin 41 protrudes outward from the upper surface of the insulation jacket main body, thereby increasing the capacity of the bin.

The side wall of the heat insulation sleeve 4 is provided with a material hole 42 which is linearly communicated with the storage bin 41 and can be closed by a transparent hole plug 5. From this, at the printing process, the user can observe the material volume in feed bin 41 through material hole 42, when printing material is not enough, can in time fill granular printing material in feed bin 41 through material hole 42. Those skilled in the art will appreciate that the orifice 42 should have a height to allow a user to view the printing material in the bin 41 over a range of heights for better viewing of the amount of material.

The heat insulating sleeve 4 further comprises air inlet holes 43, and the air inlet holes 43 penetrate from the lower surface of the heat insulating sleeve 4 to the upper surface of the heat insulating sleeve 4. The air inlet 43 is provided with a heat radiation fan 10 at the opening of the lower surface of the heat insulation sleeve 4, and the heat radiation fan 10 guides external air flow inwards to cool the heat insulation sleeve 4, the nozzle body 1 and the nozzle base 3.

The insulating sheath 4 is preferably integrally formed of a high temperature resistant insulating material such as polyetheretherketone (PEEK material).

The heating assembly 6 comprises an extrusion line 61 and a heating device 62 for heating the extrusion line 61, the extrusion line 61 is preferably a metal material. The extrusion pipeline 61 is in a hollow column shape, the first end of the extrusion pipeline 61 is communicated with the first end of the storage bin 41 in the heat insulation sleeve 4, and the printing head 7 is installed on the second end of the extrusion pipeline 61 through threads. The heating device 62 is plate-shaped, in which a heating rod 9 and a temperature sensor 8 are arranged, the heating rod 9 and the temperature sensor 8 are inserted into the small hole of the side part of the heating assembly 6 for heating and measuring the temperature of the structure of the heating assembly 6. The extrusion line 61 passes through the heating device 62, the heating device 62 is connected to at least the middle part of the extrusion line 61, and the printing material in the extrusion line 61 is heated by the direct contact of the heating device 62 and the extrusion line 61.

The heating element 6 is arranged (preferably fixed by screws) on the lower surface of the heat insulating sleeve 4, and in order to reduce the contact area between the heating element 6 and the heat insulating sleeve, a convex structure is arranged on the contact surface between the heating element 6 and the heat insulating sleeve 4. In this embodiment, the heating assembly 6 is embedded in the lower surface of the heat insulating sleeve 4, the protrusion 44 is disposed on the lower surface of the embedded position of the heat insulating sleeve 4, and the first end of the extruding pipe 61 is protruded outwardly from the upper surface of the heating device 62 to be inserted into the first end of the bin 41.

The base 3 is provided with a connecting through hole 31 and a transmission rod hole 32 which penetrate through the upper surface and the lower surface of the base 3 in parallel.

The shower nozzle main part 1 is installed on the connect through hole 31 of the upper surface of shower nozzle base 3, the heat insulating sleeve 4 is installed (preferably fixed through the screw) the downside of shower nozzle base 3, connect through hole 31 on the base 3 with the fresh air inlet 43 of heat insulating sleeve 4 sets up relatively, and from this, the outside air that has the fan 10 refluence can be through connect through hole 31 and fresh air inlet 43 to shower nozzle main part 1 cool down.

The drive rod hole 32 is aligned with the cylindrical space of the bin 41 of the sleeve 4. preferably, the second end of the bin 41 projects outwardly from the upper surface of the sleeve body and is sealingly inserted into the drive rod hole 32 of the base 3. A driving rod is placed in the driving rod hole 32, and the lower end portion of the driving rod can be inserted into the bin 41. In this embodiment, the driving rod is a push rod, and the lower end portion of the push rod has a shape matched with the inner wall of the hopper 41, so that the printing material can be pressed downward in the hopper 41 to perform the extrusion printing operation. Specifically, the putter has body of rod 12, rod cover 13 and pole head 14, is equipped with spacing portion 15 on the downside surface of the body of rod 12, rod cover 13 and pole head 14 overlap in proper order and establish the lower extreme of the body of rod 12, pole head 14 is fixed on the body of rod 12 through the screw of its tip, with the centre gripping of rod cover 13 between spacing portion 15 and the body of rod 12, wherein rod cover 13 has the biggest putter diameter.

The sprayer body 1 is provided with a control chip, a motor and an actuating mechanism. In this embodiment, the actuating mechanism is a push rod pressing plate 2, the push rod pressing plate 2 is connected with the top end of the push rod, and the control chip can drive the motor to drive the push rod pressing plate 2 and the push rod to move up and down through a lead screw, for example, so as to perform extrusion operation. Those skilled in the art will appreciate that the solution of the present embodiment is also feasible by means of screw extrusion.

In addition, the control chip is electrically connected with the temperature sensor 8, the heating rod 9 and the fan 10 through a Pogo pin interface 11 arranged at the rear part of the lower surface of the head base 3 and the rear part of the upper surface of the heat insulating sleeve 4. The control chip obtains the temperature of the heating assembly 6, controls the heating assembly 6 to heat the printing material, and simultaneously controls the starting and stopping of the fan 10.

In the embodiment of the present invention, the heat insulating sleeve 4 is formed integrally by a high temperature resistant heat insulating material such as polyetheretherketone (PEEK material), and can withstand a high temperature of about 500 ℃. The heat insulation sleeve 4 is a heat insulation layer between the heating assembly 6 and the spray head main body 1 and the spray head base 3, and is made of a material which is high temperature resistant and has slow heat conduction; meanwhile, the joint of the heat insulation sleeve 4 and the heating assembly 6 is designed into a convex structure, so that the contact area after connection is reduced; in addition, the heat insulation sleeve 4 structure is actively radiated by the wind guide of the fan 10, and the heat can be effectively prevented from being conducted to the nozzle body 1 and the nozzle base 3. The embodiment of the utility model provides a with heating element 6 imbed the lower surface of radiation shield 4 can prevent effectively exposing of heating element, reduces the scald risk to the user.

The utility model discloses high temperature 3D prints shower nozzle biological when using, add granular material from the opening in the drive rod hole 32 of 3 upper surfaces of shower nozzle base earlier, wherein, can mix the inorganic substance powder when printing macromolecular material. The granular material falls into the bin 41 of the insulating sheath 4 and into the extrusion line 61 connecting the bin 41. The push rod is then fixed to the push rod platen 2 and the heating assembly 6 continues to heat up until the material melts and the material at the heating assembly 6 melts. The push rod press plate 2 is driven to move up and down by a motor and a lead screw driving belt in the spray head main body 1, so as to push the material in the storage bin 41. Under the pushing action, the material melted at the heating assembly 6 is extruded by the printing head 7 and solidified and formed, and is continuously accumulated to realize the additive manufacturing. During the printing process, the granular material in the heat insulation sleeve 4 gradually enters the heating assembly 6 and is melted and extruded through the continuous pushing of the push rod. If the user observes through material hole 42 that the material volume in feed bin 41 is not enough, can pull out stopple 5, in time fill granular printing material in feed bin 41 through material hole 42.

In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The embodiments of the present invention have been described above. However, the present invention is not limited to the above embodiment. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The utility model provides a biological shower nozzle that prints of high temperature 3D, its characterized in that, includes shower nozzle main part (1), shower nozzle base (3), radiation shield (4) and heating element (6), shower nozzle main part (1) sets up on shower nozzle base (3), the downside of shower nozzle base (3) is connected with radiation shield (4), be provided with feed bin (41) in radiation shield (4), heating element (6) set up in radiation shield (4) or on the lower surface of radiation shield (4), heating element (6) including extrude pipeline (61) and right extrude heating element (62) of pipeline (61) heating, the first end of feed bin (41) in radiation shield (4) with the first end intercommunication of extruding pipeline (61) of heating element (6).

2. The high-temperature 3D bioprinting showerhead according to claim 1, characterized in that the silo (41) in the thermal insulation sleeve (4) has a hollow cylindrical space, the silo (41) is open at both ends and penetrates from the lower surface of the thermal insulation sleeve (4) to the upper surface of the thermal insulation sleeve (4).

3. The high temperature 3D bioprinting showerhead of claim 2, wherein a middle portion and the first end of the cartridge (41) are disposed in the thermal sleeve body, and a second end of the cartridge (41) protrudes outward from an upper surface of the thermal sleeve body.

4. The high-temperature 3D bioprinting nozzle according to claim 1, characterized in that the side wall of the heat insulating sleeve (4) is provided with a material hole (42) which is linearly communicated with the stock bin (41) and can be closed by a transparent hole plug (5).

5. The high-temperature 3D bioprinting nozzle according to claim 1, wherein the heating component (6) is integrally formed of a metallic material and/or the thermal insulating sleeve (4) is integrally formed of a polyetheretherketone material.

6. The high-temperature 3D bioprinting showerhead according to claim 1, wherein the extrusion line (61) has a hollow cylindrical shape, the heating means (62) has a plate shape, the extrusion line (61) passes through the heating means (62), and the heating means (62) is connected to at least a middle portion of the extrusion line (61).

7. The high temperature 3D bioprinting showerhead of claim 6, wherein a first end of the extrusion tubing (61) extends outwardly from an upper surface of the heating device (62) to be inserted into a first end of a cartridge (41).

8. The high-temperature 3D bioprinting showerhead according to claim 1, characterized in that on the contact surface between the heating assembly (6) and the thermal insulating sleeve (4) there is provided a raised structure.

9. The high-temperature 3D bioprinting showerhead of claim 8, characterized in that the heating element (6) is embedded in the lower surface of the thermal sleeve (4), and a raised structure (44) is provided on the lower surface of the thermal sleeve (4) where the heating element (6) is embedded.

10. The high-temperature 3D bioprinting nozzle according to claim 1, wherein the heat insulating sleeve (4) further comprises an air inlet hole (43), the air inlet hole (43) penetrates from the lower surface of the heat insulating sleeve (4) to the upper surface of the heat insulating sleeve (4), a heat radiation fan (10) is installed at the air inlet hole (43), and the heat radiation fan (10) introduces external air flow into the nozzle;

the shower nozzle is characterized in that a connecting through hole (31) penetrating through the upper surface and the lower surface of the shower nozzle base (3) is formed in the shower nozzle base (3), the shower nozzle body (1) is installed on the connecting through hole (31) in the upper surface of the shower nozzle base (3), the heat insulation sleeve (4) is installed on the lower side of the shower nozzle base (3), and the connecting through hole (31) in the shower nozzle base (3) and an air inlet hole (43) in the heat insulation sleeve (4) are arranged oppositely.

11. The high-temperature 3D bioprinting nozzle according to claim 1, wherein the nozzle base (3) is provided with a driving rod hole (32) penetrating through the upper surface and the lower surface of the nozzle base (3), the driving rod hole (32) is aligned with the cylindrical space of the storage bin (41) of the thermal insulation sleeve (4), a driving rod is placed in the driving rod hole (32), and the lower end of the driving rod can be inserted into the storage bin (41).

12. The high temperature 3D bioprinting showerhead of claim 11, wherein a second end of the cartridge (41) extends outwardly from an upper surface of the thermal sleeve body and is sealingly inserted into the drive rod aperture (32) of the showerhead base (3).

13. The high temperature 3D bioprinting showerhead of claim 11 or 12, wherein the drive link is a push rod having a lower end portion with a shape matching an inner wall of the cartridge (41); or the transmission rod is a screw rod.

14. The high-temperature 3D bioprinting nozzle according to claim 13, wherein the nozzle body (1) is provided with a control chip, a motor and a push rod pressing plate (2), the push rod pressing plate (2) is connected with the top end of the push rod, and the control chip can drive the motor to drive the push rod pressing plate (2) and the push rod to move up and down.