CN212281371U - Electric flutter-inducing device - Google Patents

Electric flutter-inducing device Download PDF

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CN212281371U
CN212281371U CN202021436573.6U CN202021436573U CN212281371U CN 212281371 U CN212281371 U CN 212281371U CN 202021436573 U CN202021436573 U CN 202021436573U CN 212281371 U CN212281371 U CN 212281371U
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electrode
module
electrically connected
flutter
impedance
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刁孟元
朱英
胡炜
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Hangzhou First Peoples Hospital
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Hangzhou First Peoples Hospital
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Abstract

The utility model discloses an electricity is induced and is quivered device, include: the first electrode and the second electrode are used for electric induction; the impedance detection module is electrically connected with the first electrode and the second electrode and used for acquiring an impedance value between the first electrode and the second electrode; the electrocardiogram monitoring module is electrically connected with the first electrode and the second electrode and is used for acquiring a real-time electrocardiogram through the first electrode and the second electrode; and the processor is electrically connected with the impedance detection module and the electrocardio monitoring module respectively. The utility model discloses an whether electrocardio, impedance information between the electrode judge and quiver electrode position correct, provide the most direct judgement foundation, the most direct position that has reflected the electrode, and need not monitor equipment or radiography equipment and can judge the electrode position.

Description

Electric flutter-inducing device
Technical Field
The utility model belongs to animal experiment field, concretely relates to electricity lures device that quivers.
Background
In the animal experiment process of medical clinic, it is often needed to make the experimental animal subject generate abnormal heart rhythm to simulate the diseased heart rhythm condition to verify the safety and effectiveness of the medical appliance or the medicine. The most common of these is to cause laboratory animals to develop ventricular fibrillation rhythms; for example, when an animal experiment is performed on a defibrillation device such as a defibrillator or an AED, the animal must generate a defibrillatable heart rhythm (usually, ventricular fibrillation heart rhythm), and the defibrillation device such as the defibrillator or the AED has an experimental treatment object to trigger the defibrillation operation of the device. Therefore, in such animal experiments, fibrillation, i.e. induction of ventricular fibrillation, is a key operation in preparation of animal experiments.
There are various methods for inducing tremor, for example, drug-induced tremor, apnea-induced tremor, and electrical tremor. Wherein the drug induced fibrillation and the asphyxia induced fibrillation can damage tissues such as cardiac muscle of animals, and form interference factors in the animal experiment process; for example, in the animal experiment process of the defibrillation equipment, the section examination of the animal cardiac muscle at the end of defibrillation treatment is required, the examination result can be used as an important factor for analyzing the safety of the defibrillation equipment, and the influence of drug-induced fibrillation and asphyxia-induced fibrillation on myocardial tissues can interfere with the analysis.
Electrically induced fibrillation is an excellent method for inducing ventricular fibrillation in animals, and affects the animals to a lesser extent. However, current methods of electrical fibrillation for laboratory use are often extensive, not precisely controlled, and prone to fibrillation failure, requiring repeated attempts to achieve successful fibrillation, depending on the skill of the laboratory operator.
Therefore, in view of the above technical problems, it is necessary to provide an electrical fluttering device.
SUMMERY OF THE UTILITY MODEL
In view of this, the utility model aims at providing an electricity is induced and is quivered device to realize the accurate control that the electricity was induced and is quivered.
In order to achieve the above object, an embodiment of the present invention provides the following technical solutions:
an electrical shiver device, the electrical shiver device comprising:
the first electrode and the second electrode are used for electric induction;
the impedance detection module is electrically connected with the first electrode and the second electrode and used for acquiring an impedance value between the first electrode and the second electrode;
the electrocardiogram monitoring module is electrically connected with the first electrode and the second electrode and is used for acquiring a real-time electrocardiogram through the first electrode and the second electrode;
and the processor is electrically connected with the impedance detection module and the electrocardio monitoring module respectively.
In an embodiment, the first electrode and the second electrode are electrically connected to the impedance detection module and the ecg monitoring module through a first switch, and the processor is further configured to control the first switch to be turned on or off.
In an embodiment, the electrical flutter-inducing device further comprises a power processing module electrically connected with the processor and a power source electrically connected with the power processing module, and the power processing module is electrically connected with the first flutter-inducing electrode and the second flutter-inducing electrode simultaneously.
In one embodiment, the power processing module is electrically connected to the first and second electrodes, and the control output module is electrically connected to the processor.
In an embodiment, the first and second electrode are electrically connected to the control output module through a second switch, and the processor is further configured to control the second switch to be turned on or off.
In one embodiment, the electric flutter inducing device further comprises a display interface module, a voice prompt module, a storage recording module and a key operation module which are electrically connected with the processor.
Compared with the prior art, the utility model has the advantages of it is following:
the utility model discloses an whether the electrocardio, the impedance information judgement of luring between the electrode quiver lures the electrode position to quiver correctly, provide the most direct judgement foundation, the most direct reflection lures the position of quiver electrode, has normal electrocardio and impedance little with ventricular inner wall contact promptly, otherwise just does not have the contact, and is simple effective, and need not more other monitor equipment or radiography equipment and can judge the electrode position.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments described in the present application, and other drawings can be obtained by those skilled in the art without creative efforts.
Fig. 1 is a schematic circuit diagram of an electrical flutter inducing device according to an embodiment of the present invention;
FIG. 2 is a flow chart of electrical flutter induction according to an embodiment of the present invention;
fig. 3 is a voltage waveform diagram of the output of the control output module according to an embodiment of the present invention;
fig. 4 is a waveform diagram of the current outputted by the control output module according to an embodiment of the present invention.
Detailed Description
The present invention will be described in detail below with reference to embodiments shown in the drawings. However, the present invention is not limited to the embodiments, and the structural, method, or functional changes made by those skilled in the art according to the embodiments are all included in the scope of the present invention.
The utility model discloses an electricity is induced and is quivered device, include:
the first electrode and the second electrode are used for electric induction;
the impedance detection module is electrically connected with the first electrode and the second electrode and used for acquiring an impedance value between the first electrode and the second electrode;
the electrocardiogram monitoring module is electrically connected with the first electrode and the second electrode and is used for acquiring a real-time electrocardiogram through the first electrode and the second electrode;
and the processor is electrically connected with the impedance detection module and the electrocardio monitoring module respectively.
The present invention will be further described with reference to the following specific examples.
Referring to fig. 1, the present embodiment discloses an electrical defibrillation apparatus, including: a electrocardio monitoring module and treater CPU for carrying out first electrode A and the second electrode B that quivers that lures of electricity, be used for acquireing the impedance value between first electrode A and the second electrode B that quivers that lures, be used for through first electrode A and the second electrode B that quivers that lures quivers acquire real-time heart electrograph.
Specific, one of them lures the electrode of quivering and places in the nearer position of animal skin surface centrifugation, another lures the electrode of quivering and places and contact with animal ventricle inner wall through having the wound intubate, impedance detection module and first luring quiver electrode A and second lures quiver electrode B electric connection, electrocardio monitoring module with first luring quiver electrode A and second lures quiver electrode B electric connection, first luring quiver electrode A and second luring quiver electrode B respectively through first switch K1 and impedance detection module and electrocardio monitoring module electric connection.
Referring to fig. 1, a processor CPU is electrically connected to an impedance detection module and an electrocardiographic monitoring module, respectively, and is configured to determine whether an impedance value is greater than a preset impedance threshold value, and determine whether a normal electrocardiographic waveform exists in a real-time electrocardiogram; when the impedance value is larger than a preset impedance threshold value and/or normal electrocardiogram waveforms do not exist in the real-time electrocardiogram, adjusting the positions of the first electrode A and the second electrode B; when the impedance value is smaller than or equal to the preset impedance threshold value and normal electrocardio waveforms exist in the real-time electrocardiogram, the first electrode A and the second electrode B are controlled to perform electric induction and fibrillation, and the processor CPU is also used for controlling the opening or closing of the first switch K1, so that the disconnection and connection between the impedance detection module and the electrocardio monitoring module as well as the first electrode A and the first electrode B are controlled.
Referring to fig. 1, the electricity lures the device that quivers still include with treater CPU electric connection's power processing module and with power processing module electric connection's power, the power is commercial power (alternating current 220V), power processing module simultaneously with first electrode A and the second electrode B electric connection that quivers that lures quivers, power processing module and first electrode A that lures quivers, electric connection has control output module between the second electrode B that lures quivers, control output module simultaneously with treater CPU electric connection, first electrode A and the second electrode B that quivers that lures quivers are respectively through second switch K2 and control output module electric connection, treater CPU still is used for controlling opening or closing of second switch K2, thereby control output module and first disconnection and the connection of luring between quiver electrode A and the first electrode B that quivers.
In this embodiment, the chip used by the CPU of the processor is STM32F103VGT6, the chip used by the electrocardiograph monitoring module is ADS1198, and the chip used by the impedance detection module is AD 5934.
Referring to fig. 1, the electric shiver device further comprises a display interface module, a voice prompt module, a storage and recording module and a key operation module which are electrically connected with the processor CPU, wherein the chip adopted by the display module is SSD1963QL9, and the chip adopted by the voice prompt module is KT 1025A.
The power supply processing module is used for supplying power to the CPU, the display interface module, the voice prompt module, the storage recording module, the key operation module and the like after voltage reduction, rectification and the like of the power supply, and also provides a flutter-inducing power supply for the control output module.
In this embodiment, the control output module is configured to adjust the flicker inducing power provided by the power processing module to a required corresponding flicker inducing voltage or current, and directly output the adjusted voltage or current to the first flicker inducing electrode a and the first flicker inducing electrode B.
In this embodiment, the key operation module includes a constant voltage mode button, a constant current mode button, an automatic mode button, a semi-automatic mode button, a start flutter-inducing button, a voltage adjusting knob, and a current adjusting knob, and is configured to control the processor CPU to enter the constant voltage mode/constant current mode, the automatic mode/semi-automatic mode, and start flutter-inducing, and adjust the voltage and the current.
The semi-automatic mode and the automatic mode can be selected according to different proficiency levels, so that the operation efficiency is improved; and under two modes, the operation can be carried out according to the prompt of the shiver inducing result, and the operation is very convenient.
Referring to fig. 3, in the constant voltage mode, the output module is controlled under the control of the processor CPU to convert the output of the power supply processing module into a bidirectional square wave (50: 50) of constant voltage output, and during the chatter induction, the amplitude of the square wave is constant V (constant, namely, the amplitude of the voltage output is constant V no matter what the detected value of the impedance is or how the detected value changes, and no matter what the disturbance and change of the load controlling the output exist in the flutter-inducing process, the current is adjusted and changed along with the load or the impedance), the V value can be preset through a voltage adjusting knob, the adjusting range of the V value is preferably 1V to 12V, the period of the square wave is T (the frequency f is 1/T), the preferred value of the square wave frequency is an electrocardiogram heart rate value obtained by the electrocardiogram monitoring module, the square wave frequency is equal to the heart rate value, and the constant current mode button and the current adjusting knob do not work in the constant voltage mode.
Referring to fig. 4, in the constant current mode, the output module is controlled under the control of the processor CPU to convert the output of the power supply processing module into a bidirectional square wave (50: 50) of constant current output, and during the flutter induction, the amplitude of the current square wave is constant I (constant, namely, the amplitude of the current output is constant I no matter how the detected value of the impedance is or how the detected value of the impedance changes, and the voltage is adjusted and changed along with the load or the impedance no matter the load controlling the output has any disturbance and change in the flutter process), the I value can be preset through a current adjusting knob, the adjusting range of the I value is preferably 1 mA-20 mA, the period of square wave is T (frequency f is 1/T), the preferable value of the square wave frequency is an electrocardiogram heart rate value obtained by the electrocardiogram monitoring module, the square wave frequency is equal to the heart rate value, and the constant voltage mode button and the voltage adjusting knob do not work in the constant current mode.
Accurate output waveform under constant voltage mode and the constant current mode, the parameter of inducing quivering is stable, definite, in the contrast of a plurality of animal experiments, can not form interference factor.
In this embodiment, the storage recording module is used for storing parameters in the electrical induction flutter process, and includes: the current curve that quivers, voltage curve, impedance record, the duration that quivers that lures record, lures the result that quivers, lures the number of times that quivers, the multinomial record of luring the parameter that quivers when a plurality of animals of being convenient for experiment contrast, as data analysis, the basis of grouping, provide the required data of more experimental analysis.
In this embodiment, the language prompt device is used to prompt the setting mode of the key operation module, and prompt the operation steps and the operation actions in the flutter-inducing process.
In this embodiment, the display interface module is used for showing the setting mode of button operation module, shows the electrocardiogram, the demonstration of quivering duration, the demonstration of the number of times of quivering and the current result of quivering that have gone on of quivering through first quivering electrode A and the first electrode B that quivers of luring of real-time display.
And continuous prompts and guidance flutter induction operation are displayed through voice and an interface, so that the use convenience is improved.
Referring to fig. 2 in combination with fig. 1, when the first electrodes a and B are ready for use, the first switch K1 is closed to keep the second switch K2 open, and the ecg monitoring module obtains a real-time ecg and the impedance detection module obtains an impedance value between the first electrode a and the first electrode B; the processor CPU identifies electrocardiogram information and an impedance value, when the electrocardiogram belongs to one of two set conditions of abnormal electrocardiogram waveform or the impedance value is larger than 10K, the fact that no electrocardiogram information exists between the first electrode A and the first electrode B, namely the fact that the electrode A of the intracardiac catheter is not in contact with the inner wall of the ventricle is indicated, and at the moment, the position of the electrode A of the intracardiac catheter is not right through voice prompt, and the position of the electrode A of the intracardiac catheter needs to be adjusted again; through judging and adjusting repeatedly, until the two set conditions do not occur, the contact between the electrode for inducing fibrillation of the intracardiac built-in tube and the inner wall of the ventricle is good, the position of the electrode for inducing fibrillation is good through voice prompt, the position of the electrode needs to be fixed, and the electrocardiogram and the specific impedance value acquired through the first electrode for inducing fibrillation A and the first electrode for inducing fibrillation B are displayed on an interface at the same time.
After the placement of the first shiver electrode A and the first shiver electrode B is completed, if the semi-automatic mode is selected, waiting time t2 is set, time t2 is preferably 5 seconds, and after waiting time t2 is finished, voice prompt and interface display are performed: can induce tremor and please press a start tremor inducing button; when the start flutter-inducing button is detected to be pressed, the first switch K1 is opened and the second switch K2 is closed, flutter-inducing output is maintained, after the time t21, preferably 3 seconds at the time t21, after the time t21 is finished, the first switch K1 is closed and the second switch K2 is opened, then the CPU immediately monitors and identifies whether the electrocardiogram waveform is a ventricular fibrillation waveform, and if the electrocardiogram waveform is not the ventricular fibrillation waveform, the waiting time t2 and the subsequent processes are repeated; and until the CPU identifies the ventricular fibrillation waveform, displaying the ventricular fibrillation waveform on the interface, prompting successful fibrillation by voice, and recording the values of the fibrillation inducing parameters in the process.
After the placement of the shiver electrode is finished, if the automatic mode is selected, waiting for a period of time t1, wherein the time t1 is preferably 15 seconds, and after the waiting time t1 is finished, displaying a voice prompt and an interface: flutter can be induced, and flutter induction is started after waiting for 10 days; after the countdown of 10 seconds is finished, automatically opening the first switch K1 and closing the second switch K2, maintaining the output of fibrillation, after the time t11, preferably 3 seconds at the time t11, and after the time t11 is finished, closing the first switch K1 and opening the second switch K2, immediately monitoring and identifying whether the electrocardiogram waveform is the ventricular fibrillation waveform by the CPU, and if the electrocardiogram waveform is not the ventricular fibrillation waveform, repeatedly waiting for the time t1 and the subsequent processes; and until the CPU identifies the ventricular fibrillation waveform, displaying the ventricular fibrillation waveform on the interface, prompting successful fibrillation by voice, and recording the values of the fibrillation inducing parameters in the process.
The parameter record content comprises: 1. the electrocardio waveform monitored by the electrocardio monitoring module in the whole process; 2. impedance value between the induced flutter electrodes; 3. and a shiver mode: constant voltage mode/constant current mode, automatic mode/semi-automatic mode; 4. the number of shivers is induced; 5. the voltage value (the value V is under the constant voltage mode, and the product of the value I and the impedance value is under the constant current mode) and the current value (the ratio between the value V and the impedance value is under the constant voltage mode, and the value I is under the constant current mode) of each flutter induction; 6. the heart rate is the constant voltage/constant current flutter-inducing square wave frequency value.
In this embodiment, in both the automatic mode and the semi-automatic mode, the bidirectional square wave for flutter output set in the constant current mode or the constant voltage mode may be output.
Referring to fig. 2, the embodiment further discloses an electrical flutter inducing method, which includes the following steps:
acquiring an impedance value between the first electrode and the second electrode, and acquiring a real-time electrocardiogram through the first electrode and the second electrode;
judging whether the impedance value is larger than a preset impedance threshold value or not, and judging whether a normal electrocardiogram waveform exists in the real-time electrocardiogram;
when the impedance value is larger than a preset impedance threshold value and/or normal electrocardiogram waveforms do not exist in the real-time electrocardiogram, adjusting the positions of the first and second electrode;
and when the impedance value is smaller than or equal to the preset impedance threshold value and normal electrocardiogram waveforms exist in the real-time electrocardiogram, controlling the first electrode and the second electrode to perform electric induction flutter.
Wherein the preset impedance threshold is 10k omega.
In the embodiment, the first and second electrode are controlled to perform electrical flutter induction in a constant voltage or constant current mode.
In the embodiment, in an automatic mode, when the impedance value is less than or equal to 10k omega and normal electrocardio waveforms exist in a real-time electrocardiogram, the electric induction flutter is automatically started after waiting for time t1, after the electric induction flutter time t11 is maintained, the electric induction flutter is stopped, whether ventricular fibrillation heart rate waveforms exist in the real-time electrocardiogram is monitored, if not, the electric induction flutter is continued, if yes, the electric induction flutter is successful, and data parameters are recorded;
in a semi-automatic mode, when the impedance value is less than or equal to 10k omega and normal electrocardio waveforms exist in the real-time electrocardiogram, waiting for time t2, manually starting electrical induction flutter, maintaining the electrical induction flutter time t21, monitoring whether ventricular fibrillation heart rate waveforms exist in the real-time electrocardiogram, if not, continuing the electrical induction flutter, and if so, successfully inducing flutter and recording data parameters.
The data parameter record content comprises: 1. the whole process monitors the electrocardio waveform, 2, the impedance value between the first electrode and the second electrode, 3, the flutter inducing mode: the method comprises the following steps of (1) a constant voltage mode/a constant current mode, an automatic mode/a semi-automatic mode, 4. the number of chattering times, 5. the chattering voltage value (namely a V value in the constant voltage mode, and the product of I and an impedance value in the constant current mode) and the current value (namely the ratio between the V and the impedance value in the constant voltage mode, and the I value in the constant current mode) of each chattering. 6. The heart rate is the constant voltage/constant current flutter-inducing square wave frequency value.
According to the technical scheme provided by the utility model, the utility model discloses following beneficial effect has:
the utility model judges whether the position of the electrode is correct or not through the electrocardiographic waveform and the impedance information between the first shiver inducing electrode and the second shiver inducing electrode, provides the most direct judgment basis, reflects the position of the electrode most directly, namely, the electrode has normal electrocardiography and small impedance when contacting with the inner wall of the ventricle, otherwise, the electrode has no contact, and is simple and effective; and the electrode position can be judged without more other monitor equipment or radiography equipment.
It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (6)

1. An electrical shiver apparatus, comprising:
the first electrode and the second electrode are used for electric induction;
the impedance detection module is electrically connected with the first electrode and the second electrode and used for acquiring an impedance value between the first electrode and the second electrode;
the electrocardiogram monitoring module is electrically connected with the first electrode and the second electrode and is used for acquiring a real-time electrocardiogram through the first electrode and the second electrode;
and the processor is electrically connected with the impedance detection module and the electrocardio monitoring module respectively.
2. The electrical defibrillation device of claim 1, wherein the first and second electrodes are electrically connected to the impedance detection module and the ecg monitoring module through a first switch, and the processor is further configured to control the first switch to be turned on or off.
3. The electrical defibrillation device of claim 1, further comprising a power processing module electrically connected to the processor and a power source electrically connected to the power processing module, wherein the power processing module is electrically connected to the first and second electrodes.
4. The electrical flutter inducing device according to claim 3, wherein a control output module is electrically connected between the power supply processing module and the first and second flutter inducing electrodes, and the control output module is simultaneously electrically connected with the processor.
5. The electrical defibrillation apparatus according to claim 4, wherein the first and second defibrillation electrodes are electrically connected to the control output module through second switches, respectively, and the processor is further configured to control the second switches to be turned on or off.
6. The electrical shiver device of claim 1, further comprising a display interface module, a voice prompt module, a memory recording module and a key operation module electrically connected to the processor.
CN202021436573.6U 2020-07-20 2020-07-20 Electric flutter-inducing device Active CN212281371U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111657927A (en) * 2020-07-20 2020-09-15 杭州市第一人民医院 Electric flutter-inducing method and device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111657927A (en) * 2020-07-20 2020-09-15 杭州市第一人民医院 Electric flutter-inducing method and device
CN111657927B (en) * 2020-07-20 2023-12-08 杭州市第一人民医院 Electro-shock device

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