CN212255877U

CN212255877U - Phase difference correction optical imaging system for mass spectrometer

Info

Publication number: CN212255877U
Application number: CN202021338402.XU
Authority: CN
Inventors: 宋家玉; 蔡克亚; 李向广
Original assignee: Autobio Experimental Instrument Zhengzhou Co Ltd
Current assignee: Autobio Experimental Instrument Zhengzhou Co Ltd
Priority date: 2020-07-09
Filing date: 2020-07-09
Publication date: 2020-12-29
Anticipated expiration: 2030-07-09

Abstract

The utility model discloses a phase difference correction optical imaging system for mass spectrometer, which comprises a bearing part with a target plate placing area, and an imaging unit obliquely arranged above the bearing part, wherein the imaging unit comprises an imaging circuit module and a photosensitive element which are coaxially arranged, and a lens arranged between the photosensitive element and the target plate placing area; the lens is obliquely arranged, and the included angle between the central line a of the lens and the central line B of the target plate placing area is B; the photosensitive element is obliquely arranged relative to the lens, and an included angle between a central line c of the photosensitive element and the central line a of the lens is delta B. The utility model discloses the advantage lies in that imaging unit and camera lens lay ingenious for every light that imaging unit sent is reflected the target plate through the camera lens and is placed the route in district unanimous basically, and then effectively improves the definition of image, obviously improves the deformability of image, ensures the detectable area of the sample that awaits measuring, improves user experience.

Description

Phase difference correction optical imaging system for mass spectrometer

Technical Field

The utility model relates to a mass spectrograph imaging technique especially relates to a phase difference correction optical imaging system for mass spectrograph.

Background

The time-of-flight mass spectrometer is a novel soft ionization biological mass spectrum developed in recent years, and is widely applied to separation and identification of substances such as polypeptides, proteins, oligonucleotides and oligosaccharides due to the advantages of wide mass detection range, mass accuracy, small sample amount, high analysis speed, strong molecular ion peak and the like.

The imaging system of the mass spectrometer determines a significant portion of the detection region. In the identification of a sample, the detection area is often determined using images obtained by an imaging system. The imaging system of the existing mass spectrometer comprises an imaging circuit module, a lens and a photosensitive element which are arranged in the mass spectrometer, and because of the limitation of the working principle of the mass spectrometer, three structural members are arranged coaxially and have a certain included angle with a target surface. The technical scheme has the following technical problems:

the annular light beam emitted by the photosensitive element is reflected to a target surface area of the target plate through the lens to form an annular area for identification, the photosensitive element and the lens are coaxially arranged, and an included angle exists between the photosensitive element and a central line b, so that the sum of optical paths of the light emitted by the photosensitive element and reaching the target surface placing area through the lens is unequal, and more fuzzy areas are formed in the image, and the image is particularly shown in figure 1; the image is stretched significantly (i.e. there is significant stretching at the edges of the perfect circle structure) due to the unequal optical paths of the light, as shown in fig. 2. At present, most manufacturers of time-of-flight mass spectrometers choose to fuzzify the technical problems when producing the devices, for example, the radius of an imaging detection area is about 2cm in the specification, and the radius of the imaging detection area is usually small in the range, so that the requirements of actual detection cannot be met. Therefore, how to design a mass spectrometer imaging system capable of improving definition and image deformation is still a technical problem which is desired to be solved by various manufacturers.

Disclosure of Invention

An object of the utility model is to provide an optical imaging system is corrected to phase difference for mass spectrograph can guarantee to form images clearly, avoids the image to warp.

In order to achieve the above purpose, the utility model adopts the following technical proposal:

the utility model discloses a phase difference correction optical imaging system for mass spectrograph, including the carrier that has target plate place the district, the imaging unit of slope setting above the carrier, imaging unit includes imaging circuit module and the photosensitive element of coaxial laying, still includes the camera lens that sets up between photosensitive element and target plate place the district; the lens is obliquely arranged, and the included angle between the central line a of the lens and the central line B of the target plate placing area is B; the photosensitive element is obliquely arranged relative to the lens, and an included angle between a central line c of the photosensitive element and the central line a of the lens is delta B.

The included angle B and the included angle delta B satisfy the following relational expression:

wherein the content of the first and second substances,Mis the magnification of the imaging unit.

The included angle delta B is 32 degrees +/-5 degrees.

The imaging unit is arranged in the protective cylinder, and the photosensitive element extends out of the protective cylinder.

The utility model discloses the advantage lies in that imaging unit and camera lens lay ingenious for every light that imaging unit sent is reflected the target plate through the camera lens and is placed the route in district unanimous basically, and then effectively improves the definition of image, obviously improves the deformability of image, ensures the detectable area of the sample that awaits measuring, improves user experience.

Drawings

Fig. 1 and 2 are imaging diagrams of a mass spectrometer imaging system in the prior art.

Fig. 3 is a schematic structural diagram of the present invention.

Fig. 4 and 5 are image effect diagrams of the imaging system of the present invention.

Detailed Description

The following describes embodiments of the present invention in detail with reference to the drawings, which are implemented on the premise of the technical solution of the present invention, and detailed embodiments and specific operation procedures are provided, but the scope of the present invention is not limited to the following embodiments.

As shown in fig. 1, the phase difference correction optical imaging system for mass spectrometer of the present invention comprises a carrier 2 (i.e. a carrier table) having a target plate placing area 1, and an imaging unit disposed above the carrier 2, wherein the imaging unit comprises an imaging circuit module 3 and a photosensitive element 4 (i.e. a CCD) connected together, and further comprises a lens 5 (the lens 5 is a convex lens) obliquely disposed between the photosensitive element 4 and the carrier 2;

the lens 5 is obliquely arranged, an included angle between the central line a of the lens 5 and the central line B of the target plate placing area 1 is B, an included angle between the central line c of the photosensitive element 4 and the central line a of the lens 5 is delta B, and the included angle B and the included angle delta B satisfy the following relational expression:

；

in the formula (I), the compound is shown in the specification,Mm ≈ 2.3 as the magnification of the imaging unit.

In actual installation, the imaging circuit module 3 can be installed in a protective cylinder, and is installed in the mass spectrometer through the protective cylinder, and the position of the photosensitive element is outside the protective cylinder; or the imaging circuit module and the photosensitive element are directly installed in the mass spectrometer, so that the light beams emitted by the photosensitive element can be completely projected on the target plate placing area (the target plate with the sample is placed on the target plate placing area).

The technical scheme of the utility model for each light of the circular light beam of constitution that photosensitive element 4 sent reachs the optical path that district 1 was placed to the target plate unanimously basically, effectively improves the definition, has improved the deformability of image. The following is a detailed description of the ray paths D, E and F emitted by the light sensing element 4 in fig. 3 as an example:

the light path D reaches the target plate placing area 1 through the light path D' after being reflected by the lens 5; the ray path E reaches the point O of the target plate placing area 1 through the ray path E' after being reflected by the lens 5; the light path F reaches the target plate placing area 1 through the light path F' after being reflected by the lens 5;

because the photosensitive element 4 and the lens 5 have an included angle delta B of 32 +/-5 degrees, the optical paths of the light path D, the light path E and the light path F are sequentially reduced, and the optical paths of the reflected light path D ', the light path E ' and the light path F ' are sequentially increased. Therefore, the light path D + the light path D ' is approximately equal to the light path E + the light path E ' is approximately equal to the light path F + the light path F '.

The utility model discloses a photosensitive element 4 sets up with camera lens 5 slope for the optical distance that each light that photosensitive element 4 sent reachs target plate and places district 1 is unanimous basically, and then guarantees that the circle that the light beam that the sensory element sent reflected to target plate and places district 1 through camera lens 5 approaches to the perfect circle structure, effectively improves the deformability of image, specifically as shown in figure 4; meanwhile, the image definition can be improved, and particularly as shown in fig. 5, the image definition in fig. 5 is obviously better than that in fig. 2 (i.e. an imaging image of the existing imaging system).

In the description of the present invention, it should be noted that the terms "front", "back", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.

Claims

1. A phase difference correction optical imaging system for a mass spectrometer comprises a bearing piece with a target plate placing area, an imaging unit obliquely arranged above the bearing piece, and a lens, wherein the imaging unit comprises an imaging circuit module and a photosensitive element which are coaxially arranged, and the lens is arranged between the photosensitive element and the target plate placing area; the method is characterized in that: the lens is obliquely arranged, and the included angle between the central line a of the lens and the central line B of the target plate placing area is B; the photosensitive element is obliquely arranged relative to the lens, and an included angle between a central line c of the photosensitive element and the central line a of the lens is delta B.

2. The phase difference correcting optical imaging system for a mass spectrometer according to claim 1, characterized in that: the included angle B and the included angle delta B satisfy the following relational expression:

3. The phase difference correcting optical imaging system for a mass spectrometer according to claim 2, characterized in that: the included angle delta B is 32 degrees +/-5 degrees.

4. The phase difference correcting optical imaging system for a mass spectrometer according to claim 1, characterized in that: the imaging unit is arranged in the protective cylinder, and the photosensitive element extends out of the protective cylinder.