CN212160479U - PCR laboratory intelligent integrated control system - Google Patents

PCR laboratory intelligent integrated control system Download PDF

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Publication number
CN212160479U
CN212160479U CN202022510142.6U CN202022510142U CN212160479U CN 212160479 U CN212160479 U CN 212160479U CN 202022510142 U CN202022510142 U CN 202022510142U CN 212160479 U CN212160479 U CN 212160479U
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detection unit
pcr laboratory
air
airflow
plc
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张大军
曾亚林
舒建
匡芳
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Sichuan Dunan Electromechanical Technology Co ltd
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Sichuan Dunan Electromechanical Technology Co ltd
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Abstract

The utility model discloses a PCR laboratory intelligence integrated control system, including the PLC controller, be used for adjusting the air conditioning unit of humiture, be used for adjusting the converter of air supply pressure, be used for controlling the electronic blast gate of air discharge size, be used for detecting the air current controller and the lighting device of air supply tuber pipe interior airflow state, the PLC controller includes programmable logic controller and extension analog module, and programmable logic controller's output links to each other with the input of extension analog module; the expansion simulation module is internally provided with a temperature detection unit, a humidity detection unit, a pressure difference detection unit and an airflow detection unit. The intelligent integrated control system for the PCR laboratory realizes the control and integration of a ventilation system, pressure and pressure difference of the PCR laboratory, and is convenient to use and manage; by integrating various functions together, the aims of saving manpower and physical force without assigning a specially-assigned person for watching are achieved.

Description

PCR laboratory intelligent integrated control system
Technical Field
The utility model belongs to the technical field of the PCR laboratory, especially, relate to a PCR laboratory intelligence integrated control system.
Background
PCR is an abbreviation for Polymerase Chain Reaction (Polymerase Chain Reaction). Is a molecular biology technique used for amplifying specific DNA fragments and can be regarded as special DNA replication in vitro; the virus content in the body of a patient can be rapidly mastered by a DNA gene tracking system, and the accuracy of the system reaches the nanometer level. For example, the number of hepatitis B viruses in a patient body, whether the hepatitis B viruses are duplicated or not, whether the hepatitis B viruses are infected or not, how strong the infection exists, whether the hepatitis B viruses need to be taken or not, whether the liver functions are abnormally changed or not can be accurately detected, which antiviral drugs are most suitable for the patient to use can be judged in time, and the curative effect of the drugs can be judged, so that a reliable inspection basis is provided for clinical treatment.
The PCR laboratory is called gene amplification laboratory, the PCR laboratory usually includes reagent preparation area, sample preparation area, gene amplification area and product analysis area, the requirement of PCR laboratory for environment is very high, the PCR laboratory must establish strict laboratory management system and establish standardized operation program, the PCR laboratory in the prior art has ventilation problem, resulting in failing to reach standard, so it has invented a dual-purpose PCR laboratory system, for example Chinese patent application No. CN202010696435.X, the utility model is a dual-purpose PCR laboratory system and its operation method Chinese invention patent, it discloses a dual-purpose PCR laboratory system and its operation method, including entering area, PCR dedicated walk, reagent preparation area, sample preparation area, gene amplification area, product analysis area, reagent preparation area including reagent preparation area independent exhaust device, reagent preparation area independent air supply device, the sample preparation area comprises a sample preparation area independent air exhaust device and a sample preparation area independent air supply device, the gene amplification area comprises a gene amplification chamber airtight window, a gene amplification area independent air exhaust device and a gene amplification area independent air supply device, and the product analysis area comprises a product analysis chamber airtight window, a product analysis area independent air exhaust device and a product analysis area independent air supply device. The dual-purpose PCR laboratory system disclosed by the invention realizes relatively independent ventilation among all the zones, does not have the condition of cross contamination, is applicable to both a normal state and an epidemic situation state, and has extremely high safety performance.
Although the PCR laboratory in the invention solves the ventilation problem, in the long-term working process of the PCR laboratory, at least the following defects are found in the PCR laboratory: because each hospital PCR laboratory has individuation design difference, equipment can not be completely unanimous when chooseing for use, consequently when using, can not rely on a system to carry out effectual control, and the equipment in a plurality of regions needs a plurality of control systems, needs the special messenger to watch on moreover to parameter variation brings the influence to the experimental procedure in the prevention test process.
Therefore, how to solve the above-mentioned drawbacks of the prior art becomes the direction of efforts of those skilled in the art.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a PCR laboratory intelligence integrated control system, ventilation system is good, and system integration is in the same place, convenient management and use, effectively solve prior art, the not good and inconvenient technical problem of system of PCR laboratory ventilation effect.
The purpose of the utility model is realized through the following technical scheme: an intelligent integrated control system for a PCR laboratory comprises a PLC (programmable logic controller), an air conditioning unit, a frequency converter, an electric air valve, an airflow controller and a lighting device, wherein the air conditioning unit is used for adjusting temperature and humidity, the frequency converter is used for adjusting air supply pressure, the electric air valve is used for controlling air exhaust volume, the airflow controller is used for detecting airflow states in an air supply duct, the PLC comprises a programmable logic controller and an extension simulation module, and the output end of the programmable logic controller is connected with the input end of the extension simulation module; the extension simulation module is internally provided with a temperature detection unit, a humidity detection unit, a pressure difference detection unit and an airflow detection unit, wherein the output end of the temperature detection unit is connected with the input end of an air conditioning unit, the air conditioning unit is connected with a compressor, the output end of the humidity detection unit is connected with the air conditioning unit, the air conditioning unit is respectively connected with a humidifier and a dehumidifier which are arranged in each room of a PCR laboratory, the output end of the pressure detection unit is connected with the input end of a frequency converter, the output end of the pressure difference detection unit is connected with the input end of an electric air valve, the output end of the airflow detection unit is connected with the input end of an airflow controller, and the airflow controller is connected with an airflow.
As a preferable mode, an illumination control unit is arranged in the PLC controller, an output end of the illumination control unit is connected with an input end of an illumination control valve arranged in each room of the PCR laboratory, and the illumination control valve is connected with an illumination device.
As a preferred mode, the PLC controller is connected to the touch screen, the touch screen is provided with a display interface, and the display interface is provided with a one-key start/stop switch, an alarm indicator, a temperature control button connected to the temperature detection unit, a humidity control button connected to the humidity detection unit, a pressure control button connected to the pressure detection unit, a pressure difference control button connected to the pressure difference detection unit, an airflow control button connected to the airflow detection unit, and an illumination control button connected to the illumination control unit.
Still include the fire prevention valve, the fire prevention valve sets up on blast pipe and the exhaust pipe in PCR laboratory, and the fire prevention valve links to each other with the PLC controller.
Compared with the prior art, the beneficial effects of the utility model reside in that: an intelligent integrated control system for a PCR laboratory realizes the control integration of a ventilation system and pressure and differential pressure of the PCR laboratory, and is convenient to use and manage; by integrating various functions together, the aims of saving manpower and physical force without assigning a specially-assigned person for watching are achieved.
Drawings
FIG. 1 is a simplified diagram of an electrical control structure in the intelligent integrated control system of the PCR laboratory.
FIG. 2 is a control schematic block diagram of the intelligent integrated control system for the PCR laboratory.
FIG. 3 is a signal flow chart of temperature control in the PCR laboratory intelligent integrated control system.
FIG. 4 is a signal flow chart of humidity control in the intelligent integrated control system of the PCR laboratory.
FIG. 5 is a signal flow chart of pressure control in the intelligent integrated control system of the PCR laboratory.
FIG. 6 is a signal flow chart of the differential pressure control in the intelligent integrated control system of the PCR laboratory.
Description of reference numerals:
and 1 is a circuit for opening and closing an electric air valve in primary filtering by a PLC (programmable logic controller).
And 2, a PLC controller is used for switching on and switching off the primary filtering medium-voltage differential switch.
And 3, a PLC controller is used for opening and closing the communication of the middle-temperature-section outdoor unit in the primary filtering.
And 4, a PLC controller is used for opening and closing the humidifying section in the primary filtering.
And 5, a line for controlling the starting and stopping of the fan of the blower in the primary filtering by the PLC.
And 6, a PLC controller is used for opening and closing the air-lack pressure difference switch of the fan in the primary filtering.
And 7 is a line for opening and closing the switch of the sub-high efficiency filter by the PLC controller.
And 8, a PLC controller is used for switching on and switching off the sub-high-efficiency filtering medium-temperature humidity sensor.
And 9 is a transmission control circuit of the PLC to the pressure sensor at the air outlet in the sub-high-efficiency filtration.
And 10 is a control circuit of the PLC to the fire-proof valve.
11 is a control circuit for opening an electric air valve of a PCR system room in the sub-high efficiency filtration by a PLC controller.
And 12 is a line for controlling the temperature and humidity sensor between the PLC and the TMT.
Reference numeral 13 denotes a line for controlling the pressure sensor between the PLC controller and the PT.
And 14 is a control circuit for opening the electric air valve of the PCR system room by the PLC.
And 15 is a control circuit for the temperature and humidity sensor between the PLC and the TMT.
And 16 is a circuit for controlling the high-efficiency filter by the PLC.
And 17 is a line for controlling the start and stop of the fan of the exhaust fan in the high-efficiency filtering process by the PLC.
18 is a start-stop control circuit of the PLC controller to the wind lack pressure difference switch of the fan.
19 is a control circuit for starting and stopping the electric air valve at the exhaust pipe after the high-efficiency filtration by the PLC controller.
And 20 refers to a fan control device.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
As shown in fig. 1 and 2, an intelligent integrated control system for a PCR laboratory comprises a PLC controller, an air conditioning unit for adjusting temperature and humidity, a frequency converter for adjusting air supply pressure, an electric air valve for controlling air discharge, an airflow controller for detecting airflow state in an air supply duct, and a lighting device, wherein the PLC controller comprises a programmable logic controller and an extension analog module, and an output end of the programmable logic controller is connected with an input end of the extension analog module; the extension simulation module is internally provided with a temperature detection unit, a humidity detection unit, a pressure difference detection unit and an airflow detection unit, wherein the output end of the temperature detection unit is connected with the input end of an air conditioning unit, the air conditioning unit is connected with a compressor, the output end of the humidity detection unit is connected with the air conditioning unit, the air conditioning unit is respectively connected with a humidifier and a dehumidifier which are arranged in each room of a PCR laboratory, the output end of the pressure detection unit is connected with the input end of a frequency converter, the output end of the pressure difference detection unit is connected with the input end of an electric air valve, the output end of the airflow detection unit is connected with the input end of an airflow controller, and the airflow controller is connected with an airflow. And an illumination control unit is arranged in the PLC, the output end of the illumination control unit is connected with the input end of an illumination control valve arranged in each room of the PCR laboratory, and the illumination control valve is connected with an illumination device. The PLC controller is connected with the touch screen, a display interface is arranged on the touch screen, and a one-key start-stop switch, an alarm indicator lamp, a temperature regulation button connected with the temperature detection unit, a humidity regulation button connected with the humidity detection unit, a pressure regulation button connected with the pressure detection unit, a pressure difference regulation button connected with the pressure difference detection unit, an airflow regulation button connected with the airflow detection unit and an illumination control button connected with the illumination control unit are arranged on the display interface.
In addition, still include the fire prevention valve, the fire prevention valve sets up on blast pipe and the exhaust pipe in PCR laboratory, and the fire prevention valve links to each other with the PLC controller.
The PCR laboratory adopts an electronic box circuit plug etc. to integrate together, and the electronic box class sets up earth leakage protection air switch and switching power supply, can play electric leakage, short circuit, overload's protection, improves holistic security.
The programmable logic controller in the PLC controller is used for executing relevant instructions facing users by facing different PCR laboratories, and other modules in the PLC controller, particularly an extension simulation module, wherein a temperature detection unit, a humidity detection unit, a pressure difference detection unit and an airflow detection unit are all existing modularized products and only need to be connected with the programmable logic controller, so that the functions of detecting and controlling the temperature, the humidity, the opening, the closing and the size of an electric air valve, the operation opening, the operation closing of a fan, the pressure difference and the airflow can be achieved. Three-stage filtering is performed in a PCR laboratory, so that the corresponding information acquisition situation also relates to the information acquisition of each point.
Specifically, as shown in fig. 3, fig. 3 is a signal flow chart of temperature control in the PCR laboratory intelligent integrated control system, a set temperature of each room in the PCR laboratory is set in advance in a PLC controller, the PLC controller communicates with an air conditioning unit through an RS485 bus cable, the air conditioning unit detects the temperature in each room, a temperature difference is obtained by comparing the detected temperature with the set temperature, the operating frequency or the number of compressors is controlled through the PLC controller, the temperature difference is eliminated, and the purpose that the temperature in the PCR laboratory can be always kept at the set value is obtained.
As shown in fig. 4, fig. 4 is a signal flow chart of humidity control in the PCR laboratory intelligent integrated control system, the set humidity of each room in the PCR laboratory is set in advance in the PLC controller, the PLC controller communicates with the air conditioning unit through an RS485 bus cable, the air conditioning unit detects the humidity in each room, a humidity difference is obtained by comparing the detected humidity with the set humidity, the PLC controller controls the humidifier to humidify or reduce the humidity through a dehumidifier, so that the humidity difference is eliminated, and the purpose that the humidity in the PCR laboratory can always maintain the set value is obtained.
As shown in fig. 5, fig. 5 is a signal flow chart of pressure control in the PCR laboratory intelligent integrated control system, the set pressure of each room in the PCR laboratory is set in advance in the PLC controller, the PLC controller communicates with the frequency converter through the RS485 bus cable, the frequency converter detects the pressure in each room, the detected pressure is compared with the set pressure to obtain a pressure difference, the frequency converter outputs the frequency through the PLC controller, thereby controlling the rotating speed of the blower, and stabilizing the blowing pressure within the set value range, and the normally set range is: 4-20mA and 0-10V.
As shown in fig. 6, fig. 6 is a signal flow chart of pressure difference control in the PCR laboratory intelligent integrated control system, a set pressure difference of each room in the PCR laboratory is set in advance in a PLC controller, the PLC controller communicates with an electric air valve through an RS485 bus cable, the electric air valve detects the pressure difference in each room, the detected pressure difference is compared with the set pressure difference to obtain a pressure difference, and the PLC controller controls the opening of the electric air valve for air exhaust, thereby controlling the air volume for air exhaust and stabilizing the indoor pressure difference within a set value range.
As shown in fig. 1, a PLC controller performs integrated control on the whole PCR laboratory, and the main circuits relate to the following:
the circuit 1 is a circuit for opening and closing the electric air valve in the primary filtering by the PLC.
And the line 2 is a line for opening and closing the primary filtering medium-voltage differential switch by the PLC.
And the line 3 is a line for opening and closing the communication of the middle-cooling-section outdoor unit in the primary filtering by the PLC.
And the line 4 is a line for opening and closing the humidifying section in the primary filtering by the PLC controller.
And the line 5 is a line for controlling the starting and stopping of the fan of the blower in the primary filtering by the PLC.
And the line 6 is a line for opening and closing the air-lack differential pressure switch of the fan in the primary filtering by the PLC.
Line 7 is a line for the PLC controller to turn on and off the switch of the sub-high efficiency filter.
And the line 8 is a line for opening and closing the sub-high-efficiency filtering medium-temperature and humidity sensor by the PLC.
The line 9 is a transmission control line of the PLC controller for the pressure sensor at the air outlet of the sub-efficient filtering medium-pressure air supply.
The circuit 10 is a control circuit of the PLC to the fire-proof valve, and realizes the fire-fighting interlocking: the air conditioning system is interlocked with the fire-proof valve of the air supply pipe and the exhaust pipe, the fire-proof valve acts, and the air conditioning system stops running. In the specific implementation process, the fire damper is closed by a smoke sensing signal or is fused and closed at 70 ℃.
The line 11 is a control line for the PLC to open the electric air valve of the PCR system room in the sub-high efficiency filtration.
The line 12 is a line between the PLC controller and the TMT for controlling the temperature and humidity sensor.
Line 13 is the line between the PLC controller and the PT that controls the pressure sensor.
Line 14 is a control line for the PLC to open the electric air valve in the PCR system room.
The line 15 is a control line for the temperature and humidity sensor between the PLC controller and the TMT.
Line 16 is the line that the PLC controller controls the high efficiency filter.
The line 17 is a line for controlling the start and stop of the fan of the exhaust fan in the high-efficiency filtering process by the PLC.
The line 18 is a start-stop control line of the PLC controller for the wind lack pressure difference switch of the fan.
The line 19 is a control line for starting and stopping the electric air valve at the exhaust pipe after the high-efficiency filtration by the PLC.
Reference numeral 20 in fig. 1 denotes a fan control device for controlling the exhaust fan.
The control of the PCR laboratory through the above main lines is as follows:
displaying main operation parameters of the system: the fan, the electric humidification, the electric air valve, the air supply pressure, the return air temperature and humidity, the room pressure and the room temperature and humidity are all displayed and controlled through the touch screen.
A temperature and humidity control system is configured, indoor temperature and humidity can be set, and temperature and humidity control is carried out according to a humidity priority principle:
summer: in the conventional operation mode, the outdoor unit is opened to meet the indoor humidity requirement, and the opening of electric heating is adjusted to control the air supply temperature so as to meet the indoor temperature requirement.
In winter: in the normal mode, the temperature of the supplied air is adjusted by adjusting the opening of the outdoor unit, and the humidity of the supplied air is controlled by controlling the opening of the electric humidification.
Season change: when season changes, the outdoor unit stops working, and outdoor air is filtered and then directly sent into a room.
When the device is on duty, the air feeder runs at low frequency, and the exhaust fan is closed; and automatically operates according to the set system disinfection mode, internal circulation time and emptying time.
In addition, for the safety problem, the filter is provided with a pressure difference alarm, and the alarm pressure value of each stage of filter is as follows: primary filter: 100 Pa; an intermediate-efficiency filter: 200 Pa; a high-efficiency filter: 400 Pa.
Normal operation of the purification air-conditioning system, and a starting and shutdown program: starting up: opening the electric air valve in advance for 20S, and opening the exhaust fan in advance for 20S; shutdown: and the exhaust fan is closed after 20S delay corresponding to the delay of the electric air valve.
The air flow switch detects the air flow state in the air supply pipeline, when the fan operation is normal, the fan operation feedback signal is normal, the air flow switch is in the normally open state according to the exhaust pipe air flow, when the fan operation is abnormal, if the belt pulley breaks, when making the motor be in the idle running state, the fan operation feedback signal is normal, the air flow switch is in the normally closed state, with this judgement fan in abnormal state, linkage fan stop motion.
The above description is only exemplary of the present invention and should not be taken as limiting the scope of the present invention, as any modifications, equivalents, improvements and the like made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.

Claims (4)

1. The utility model provides a PCR laboratory intelligence integrated control system which characterized in that: the air conditioner comprises a PLC (programmable logic controller), an air conditioning unit for adjusting temperature and humidity, a frequency converter for adjusting air supply pressure, an electric air valve for controlling air exhaust volume, an air flow controller for detecting the air flow state in an air supply duct and a lighting device, wherein the PLC comprises a programmable logic controller and an extension simulation module, and the output end of the programmable logic controller is connected with the input end of the extension simulation module; the extension simulation module is internally provided with a temperature detection unit, a humidity detection unit, a pressure difference detection unit and an airflow detection unit, wherein the output end of the temperature detection unit is connected with the input end of an air conditioning unit, the air conditioning unit is connected with a compressor, the output end of the humidity detection unit is connected with the air conditioning unit, the air conditioning unit is respectively connected with a humidifier and a dehumidifier which are arranged in each room of a PCR laboratory, the output end of the pressure detection unit is connected with the input end of a frequency converter, the output end of the pressure difference detection unit is connected with the input end of an electric air valve, the output end of the airflow detection unit is connected with the input end of an airflow controller, and the airflow controller is connected with an airflow.
2. The intelligent integrated control system for the PCR laboratory according to claim 1, wherein: and an illumination control unit is arranged in the PLC, the output end of the illumination control unit is connected with the input end of an illumination control valve arranged in each room of the PCR laboratory, and the illumination control valve is connected with an illumination device.
3. The intelligent integrated control system for the PCR laboratory according to claim 2, wherein: the PLC controller is connected with the touch screen, a display interface is arranged on the touch screen, and a one-key start-stop switch, an alarm indicator lamp, a temperature regulation button connected with the temperature detection unit, a humidity regulation button connected with the humidity detection unit, a pressure regulation button connected with the pressure detection unit, a pressure difference regulation button connected with the pressure difference detection unit, an airflow regulation button connected with the airflow detection unit and an illumination control button connected with the illumination control unit are arranged on the display interface.
4. The intelligent integrated control system for the PCR laboratory according to claim 1, wherein: still include the fire prevention valve, the fire prevention valve sets up on blast pipe and the exhaust pipe in PCR laboratory, and the fire prevention valve links to each other with the PLC controller.
CN202022510142.6U 2020-11-04 2020-11-04 PCR laboratory intelligent integrated control system Active CN212160479U (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
CN202022510142.6U CN212160479U (en) 2020-11-04 2020-11-04 PCR laboratory intelligent integrated control system

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Publication Number Publication Date
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112815440A (en) * 2021-01-07 2021-05-18 广东金鑫净化科技股份有限公司 Air volume balancing system for medical PCR laboratory
CN113757917A (en) * 2021-09-06 2021-12-07 江苏苏净工程建设有限公司 Detection control method and system for faults of three-level or above biological safety laboratory blower

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112815440A (en) * 2021-01-07 2021-05-18 广东金鑫净化科技股份有限公司 Air volume balancing system for medical PCR laboratory
CN113757917A (en) * 2021-09-06 2021-12-07 江苏苏净工程建设有限公司 Detection control method and system for faults of three-level or above biological safety laboratory blower

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