CN212142654U

CN212142654U - Micro-fluidic chip based on photocuring printing

Info

Publication number: CN212142654U
Application number: CN201921525492.0U
Authority: CN
Inventors: 胡丛余
Original assignee: Shanghai Renjing Biological Technology Co ltd
Current assignee: Shanghai Renxin Biotechnology Co.,Ltd.
Priority date: 2019-09-12
Filing date: 2019-09-12
Publication date: 2020-12-15
Anticipated expiration: 2029-09-12

Abstract

The utility model discloses a micro-fluidic chip based on photocuring prints especially relates to micro-fluidic chip technical field, including the micro-fluidic chip body, the micro-fluidic chip body includes roof, chip main part and bottom plate, and parallel distribution about roof and bottom plate are, and the middle part of chip main part centre gripping between roof and bottom plate, roof include that the top inhales strip and top buffering frame. This kind of micro-fluidic chip based on photocuring prints, when adopting photosensitive resin to realize 3D printing technology processing, roof and bottom plate need not be fixed through bolt and nut, make and utilize the top to inhale the strip and insert the bottom and inhale the slot of strip in and realize the joint, it is not only more convenient to install, and can avoid roof and bottom plate phenomenon of breaking to appear, it is fixed with chip main part centre gripping through bolt and nut between prior art roof and the bottom plate to have overcome, it is not only troublesome between roof and the bottom plate to install the chip main part like this, and make roof and bottom plate defects such as broken by organic glass easily.

Description

Micro-fluidic chip based on photocuring printing

Technical Field

The utility model relates to a micro-fluidic chip technical field especially relates to micro-fluidic chip based on photocuring is printed.

Background

The micro-fluidic chip technology integrates basic operation units of sample preparation, reaction, separation, detection and the like in the biological, chemical and medical analysis process into a micron-scale chip to automatically complete the whole analysis process, and has been developed into a brand-new research field crossed with disciplines such as biology, chemistry, medicine, fluid, electronics, materials, machinery and the like due to the huge potential of the micro-fluidic chip in the fields such as biology, chemistry, medicine and the like, and the micro-fluidic chip comprises: platinum resistance chip, pressure sensing chip, electrochemical sensing chip, micro/nano reactor chip, micro-fluid fuel cell chip, micro/nano fluid filtering chip, etc. the micro-fluidic chip is the hotspot field of the current micro total analysis system development, the micro-fluidic chip analysis takes the chip as an operation platform, simultaneously takes the analytical chemistry as the basis, relies on the micro-electro-mechanical processing technology, takes the micro-pipeline network as the structural characteristic, takes the life science as the main application object at present, and is the key point of the current micro total analysis system field development, and the aim of the micro-fluidic chip is to integrate the functions of the whole laboratory, including sampling, dilution, reagent adding, reaction, separation, detection, etc., on the micro-chip and can be used for multiple times, wherein the micro-fluidic chip based on photocuring printing adopts photosensitive resin, can realize processing through 3D printing technology, and has the advantages of short preparation period, high yield, Low cost, less required equipment, strong customizability and the like.

However, according to the microfluidic chip printed based on photocuring according to the chinese publication No. CN208717354U, which includes a top plate, a bottom plate and a chip main body, the existing microfluidic chip printed based on photocuring is obtained, and the chip main body is clamped and fixed between the top plate and the bottom plate by bolts and nuts, so that the installation of the chip main body between the top plate and the bottom plate is not only too troublesome, but also the top plate and the bottom plate made of organic glass are easily broken.

SUMMERY OF THE UTILITY MODEL

In order to overcome between prior art roof and the bottom plate through the bolt and the nut with chip main part centre gripping fixed, install the chip main part not only troublesome between roof and the bottom plate like this, make the roof and the defects such as bottom plate breakage made by organic glass in addition easily, the utility model provides a micro-fluidic chip based on photocuring printing is not only convenient for install the chip main part between roof and the bottom plate, can avoid appearing the roof and the broken phenomenon of bottom plate made by organic glass in addition.

The utility model provides a technical scheme that its technical problem adopted is: the micro-fluidic chip based on photocuring printing comprises a micro-fluidic chip body, wherein the micro-fluidic chip body comprises a top plate, a chip main body and a bottom plate, the top plate and the bottom plate are distributed in an up-down parallel manner, the chip main body is clamped in the middle between the top plate and the bottom plate, the top plate comprises a top suction strip and a top buffering frame, the number of the top buffering frames is two, the two top buffering frames are respectively bonded on the front side and the rear side of the lower end of the top plate through adhesives, the two top suction strips are respectively bonded on the front side and the rear side of the lower end of the top plate through adhesives, the top suction strip is positioned in the opening of the top buffering frame and tightly bonded with the top buffering frame, the front end and the rear end of each top suction strip are horizontally and uniformly bonded with at least six clamping blocks, the bottom plate comprises a bottom, the two bottom absorbing strips are respectively adhered to the front side and the rear side of the upper end of the bottom plate through adhesives, the upper end of each bottom absorbing strip is provided with a slot, the top absorbing strip is inserted into the slot, the number of the bottom buffering frames is two, the two bottom buffering frames are adhered to the upper ends of the two bottom absorbing strips in a one-to-one correspondence mode through adhesives, the bottom buffering frames are located around the slots, and the front end and the rear end of the inner wall of each slot are horizontally and uniformly provided with at least six clamping grooves; the top buffering frame is in contact with the bottom buffering frame, the lower end of the top buffering frame is uniformly provided with at least eight engaging teeth, and the upper end of the bottom buffering frame is uniformly provided with at least eight engaging grooves.

Preferably, the chip body consists of a concentration gradient chip, a bonding film and a cell culture chip which are sequentially stacked.

Preferably, the frame openings of the top buffer frame and the bottom buffer frame are both rectangular structures, and the top buffer frame and the bottom buffer frame are both made of foam plastics.

Preferably, the fit teeth are inserted into the fit grooves and clamped with the fit grooves, and the number and the arrangement of the fit teeth correspond to those of the fit grooves one to one.

Preferably, the top suction strip and the bottom suction strip are both made of neodymium iron boron magnets, and the top suction strip is inserted into the slot and is attracted with the bottom suction strip.

Preferably, the clamping blocks are made of rubber magnets, the clamping blocks are inserted into the clamping grooves and attract the bottom absorbing strips, and the clamping blocks correspond to the clamping grooves one to one.

Compared with the prior art, the utility model discloses the beneficial effect who realizes: according to the micro-fluidic chip based on photocuring printing, when 3D printing technology processing is realized by adopting photosensitive resin, the top plate and the bottom plate do not need to be fixed through bolts and nuts, so that clamping is realized by inserting the top suction strip into the slot of the bottom suction strip, the micro-fluidic chip is more convenient to mount, and the phenomenon that the top plate and the bottom plate are cracked can be avoided; can inhale the strip through bottom buffering frame and top buffering frame at the concatenation top and inhale the strip with the bottom, play the cushioning effect between roof and the bottom plate, simultaneously, insert through agreeing with the tooth and agree with the inslot, can prevent that the phenomenon of skew appears in roof and bottom plate when installing the chip main part.

Drawings

The invention is described in further detail below with reference to the following figures and detailed description:

FIG. 1 is a general schematic view of the present invention;

fig. 2 is a schematic view of the lower end of the top plate of the present invention;

fig. 3 is a schematic view of the bottom plate of the present invention.

In the figure: 10-top plate, 11-top suction strip, 12-clamping block, 13-top buffer frame, 14-conjunction tooth, 20-chip body, 30-bottom plate, 31-bottom suction strip, 32-bottom buffer frame, 33-conjunction groove, 34-slot and 35-slot.

Detailed Description

The following description is provided for illustrative purposes, and other advantages and features of the present invention will become apparent to those skilled in the art from the following detailed description.

As shown in fig. 1 to 3, the micro-fluidic chip based on photo-curing printing comprises a micro-fluidic chip body, wherein the micro-fluidic chip body comprises a top plate 10, a chip main body 20 and a bottom plate 30, the top plate 10 and the bottom plate 30 are distributed in a vertical parallel manner, the chip main body 20 is clamped in the middle between the top plate 10 and the bottom plate 30, the top plate 10 comprises two top suction strips 11 and two top buffer frames 13, the two top buffer frames 13 are respectively bonded to the front side and the rear side of the lower end of the top plate 10 through adhesives, the two top suction strips 11 are respectively bonded to the front side and the rear side of the lower end of the top plate 10 through adhesives, the top suction strips 11 are located inside the frame openings of the top buffer frames 13 and tightly bonded to the top buffer frames 13, and at least six fixture blocks 12 are horizontally and uniformly bonded to the front end and the rear end of each top suction, the bottom plate 30 comprises a bottom suction strip 31 and a bottom buffering frame 32, the bottom suction strip 31 is totally two, the bottom suction strip 31 is respectively bonded on the front side and the rear side of the upper end of the bottom plate 30 through a bonding agent, each bottom suction strip 31 is provided with an upper end which is provided with a slot 34, the top suction strip 11 is spliced with the slot 34, the bottom buffering frame 32 is totally two, the bottom buffering frame 32 is bonded on the upper ends of the two bottom suction strips 31 through a bonding agent in a one-to-one correspondence manner, the bottom buffering frame 32 is positioned around the slot 34, each slot 34 is provided with at least six clamping grooves 35 at the front end and the rear end of the inner wall, the chip main body 20 is composed of a concentration gradient chip, a bonding film and a cell culture chip which are sequentially superposed, the frame mouths of the top buffering frame 13 and the bottom buffering frame 32 are both in rectangular structures, and the top buffering frame 13 and the, the top absorbing strip 11 and the bottom absorbing strip 31 are both made of neodymium iron boron magnet, the top absorbing strip 11 is inserted into the slot 34 and is absorbed with the bottom absorbing strip 31, the fixture block 12 is made of rubber magnet, the fixture block 12 is inserted into the clamping groove 35 and attracted with the bottom attraction strip 31, the clamping blocks 12 correspond to the clamping grooves 35 one by one, and by clamping the chip main body 20 between the top plate 10 and the bottom plate 30, can attract the bottom suction strip 31 along with the top suction strip 11 inserted into the slot 34 of the bottom suction strip 31, so that the top plate 10 and the bottom plate 30 are clamped, the chip body 20 is clamped and fixed between the top plate 10 and the bottom plate 30, so that the top plate 10 and the bottom plate 30 do not need to be fixed by bolts and nuts while the 3D printing technology processing is realized by adopting the photosensitive resin, this not only facilitates the installation, but also prevents the top plate 10 and the bottom plate 30 from being broken.

In addition, when the top absorbing strip 11 is inserted into the slot 34 of the bottom absorbing strip 31, the latch 12 is inserted into the slot 35 to attract the bottom absorbing strip 31 along with the corresponding of the latch 12 and the slot 35, and the latch 12 has flexibility, so that the stability between the top plate 10 and the bottom plate 30 is further enhanced.

As shown in fig. 1 to 3, according to the embodiment, the difference between the embodiment and the embodiment is that the top buffer frame 13 contacts the bottom buffer frame 32, the lower end of the top buffer frame 13 is uniformly provided with at least eight fitting teeth 14, the upper end of the bottom buffer frame 32 is uniformly provided with at least eight fitting grooves 33, the fitting teeth 14 are inserted into the fitting grooves 33 and clamped with the fitting grooves 33, the number and arrangement of the fitting teeth 14 correspond to the number and arrangement of the fitting grooves 33 one by one, the bottom buffer frame 32 and the top buffer frame 13 can play a role in buffering between the top plate 10 and the bottom plate 30 when the top suction bar 11 and the bottom suction bar 31 are spliced, and meanwhile, the fitting teeth 14 are inserted into the fitting grooves 33, so that the phenomenon that the top plate 10 and the bottom plate 30 are shifted when the chip main body 20 is mounted can be prevented.

The basic principles and the main features of the invention and the advantages of the invention have been shown and described above. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. Micro-fluidic chip based on photocuring printing, including the micro-fluidic chip body, its characterized in that:

the micro-fluidic chip body comprises a top plate (10), a chip main body (20) and a bottom plate (30), wherein the top plate (10) and the bottom plate (30) are distributed in an up-down parallel manner, the chip main body (20) is clamped in the middle between the top plate (10) and the bottom plate (30), the top plate (10) comprises two top suction strips (11) and two top buffering frames (13), the two top buffering frames (13) are respectively bonded on the front side and the rear side of the lower end of the top plate (10) through adhesives, the two top suction strips (11) are respectively bonded on the front side and the rear side of the lower end of the top plate (10) through adhesives, the top suction strips (11) are located in the frame openings of the top buffering frames (13) and tightly bonded with the top buffering frames (13), and at least six fixture blocks (12) are horizontally and uniformly bonded at the front end and the rear end of each top suction strip (11), the bottom plate (30) comprises bottom suction strips (31) and bottom buffering frames (32), the number of the bottom suction strips (31) is two, the two bottom suction strips (31) are respectively bonded to the front side and the rear side of the upper end of the bottom plate (30) through bonding agents, slots (34) are formed in the upper end of each bottom suction strip (31), the top suction strips (11) are connected with the slots (34) in an inserting mode, the number of the bottom buffering frames (32) is two, the two bottom buffering frames (32) are correspondingly bonded to the upper ends of the two bottom suction strips (31) one by one through bonding agents, the bottom buffering frames (32) are located around the slots (34), and at least six clamping grooves (35) are horizontally and uniformly formed in the front end and the rear end of the inner wall of each slot (34); the buffer frame is characterized in that the top buffer frame (13) is in contact with the bottom buffer frame (32), at least eight engaging teeth (14) are uniformly arranged at the lower end of the top buffer frame (13), and at least eight engaging grooves (33) are uniformly formed in the upper end of the bottom buffer frame (32).

2. The photocuring-printing-based microfluidic chip of claim 1, wherein: the chip main body (20) is composed of a concentration gradient chip, a bonding film and a cell culture chip which are sequentially superposed.

3. The photocuring-printing-based microfluidic chip of claim 1, wherein: the frame openings of the top buffer frame (13) and the bottom buffer frame (32) are rectangular structures, and the top buffer frame (13) and the bottom buffer frame (32) are both made of foam plastics.

4. The photocuring-printing-based microfluidic chip of claim 1, wherein: the fitting teeth (14) are inserted into the fitting grooves (33) and clamped with the fitting grooves (33), and the number and the arrangement of the fitting teeth (14) correspond to those of the fitting grooves (33) one by one.

5. The photocuring-printing-based microfluidic chip of claim 1, wherein: the top is inhaled strip (11) and bottom and is inhaled strip (31) and make by neodymium iron boron magnetism iron, the top is inhaled strip (11) and is inserted inside slot (34) and inhale strip (31) mutually with the bottom and inhale strip (31).

6. The photocuring-printing-based microfluidic chip of claim 5, wherein: the fixture blocks (12) are made of rubber magnets, the fixture blocks (12) are inserted into the clamping grooves (35) and attract the bottom absorbing strips (31), and the fixture blocks (12) correspond to the clamping grooves (35) one to one.