CN212101946U - Sterile filtering and subpackaging device for micro-bottles - Google Patents

Sterile filtering and subpackaging device for micro-bottles Download PDF

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Publication number
CN212101946U
CN212101946U CN202020604799.6U CN202020604799U CN212101946U CN 212101946 U CN212101946 U CN 212101946U CN 202020604799 U CN202020604799 U CN 202020604799U CN 212101946 U CN212101946 U CN 212101946U
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China
Prior art keywords
liquid
liquid injection
micro
bottle
biological products
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CN202020604799.6U
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Chinese (zh)
Inventor
乔红霞
孙静静
周雷鸣
周伟伟
赵巧辉
李桂林
付光宇
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Zhengzhou Immuno Biotech Co Ltd
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Zhengzhou Immuno Biotech Co Ltd
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  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The utility model discloses a micro-bottle sterile filtration split charging device, which comprises a liquid injection part of a built-in liquid containing cavity for instilling liquid biological products into a split charging bottle, and a supporting part for clamping and fixing the liquid injection part; the front end liquid outlet of the liquid injection part is movably connected with a filtering part used for filtering liquid biological products, the rear end of the liquid injection part is hermetically communicated with a liquid infusion part, and the liquid inlet end of the liquid infusion part extends to a position close to the bottom of an inner cavity of a liquid containing part used for containing the liquid biological products. The utility model has the advantages of simple structure, easy disassembly and assembly, and low manufacturing cost. Automatic liquid injection is realized through a peristaltic pump, and accurate subpackage of liquid biological products is ensured; except the disposable sterile filter membrane, other parts can be sterilized and reused, so that the experimental operation cost is greatly reduced; the artificial intervention is greatly reduced, the risk of polluting liquid biological products and the risk of polluting operating personnel by microorganisms are reduced, and the experimental process is time-saving, labor-saving, safe and reliable.

Description

Sterile filtering and subpackaging device for micro-bottles
Technical Field
The utility model belongs to the technical field of the aseptic technique of filtering in laboratory and specifically relates to a sterile filtration partial shipment device of trace bottle is related to.
Background
In the existing laboratory, when liquid biological products are filtered and small bottles are subpackaged, the laboratory personnel adopt a needle cylinder to carry out manual operation, the efficiency is low, and the pollution is easy. In addition, because of the volume of cylinder is limited, and the driving force comes from operating personnel, when the volume that needs to filter and partial shipment is great, need frequently absorb liquid biological product with the cylinder and frequently filter the partial shipment, can consume a large amount of time and physical power of staff, lead to the efficiency of filtering and partial shipment very low, can't satisfy actual demand.
Disclosure of Invention
The utility model aims to provide a simple structure, easy and simple to handle's aseptic filtration partial shipment device of trace bottle.
In order to achieve the above purpose, the utility model can adopt the following technical proposal:
the sterile filtering and subpackaging device for the micro bottles comprises a liquid injection part and a supporting and fixing part, wherein the liquid injection part is used for instilling liquid biological products into the subpackaging bottles and is internally provided with a liquid containing cavity; the front end liquid outlet of the liquid injection part is movably connected with a filtering part used for filtering liquid biological products, the rear end of the liquid injection part is hermetically communicated with a liquid infusion part, and the liquid inlet end of the liquid infusion part extends to a position close to the bottom of an inner cavity of a liquid containing part used for containing the liquid biological products.
The liquid injection part is an injection needle cylinder, and a sealing rubber plug is arranged at the rear end of the injection needle cylinder.
The filtering part is a disposable sterile filter membrane which is arranged on a liquid outlet at the front end of the liquid injection needle cylinder in a matching way.
The infusion part is composed of an infusion hose and a peristaltic pump arranged on the infusion hose, and the liquid outlet end of the infusion hose penetrates through the sealing rubber plug in a sealing mode to be communicated with a liquid containing cavity in the liquid injection needle cylinder.
The supporting and fixing part comprises a horizontal base, a longitudinal supporting rod is vertically fixed on the horizontal base, the longitudinal supporting rod is connected with a horizontal supporting rod through a sliding piece, and one end of the horizontal supporting rod is provided with a pipe clamp used for clamping and fixing the liquid injection needle cylinder; the sliding piece is a longitudinal adjusting sleeve which is movably sleeved on the longitudinal supporting rod and is provided with a jacking bolt; and flexible anti-slip pads are arranged on the two opposite clamping surfaces of the pipe clamp.
The liquid containing part is a beaker with an open structure, and a volume marking line is arranged on the outer wall of the beaker along the height direction.
The utility model has the advantages of simple structure, easy disassembly and assembly, and low manufacturing cost. Automatic liquid injection is realized through a peristaltic pump, and accurate subpackage of liquid biological products is ensured; except the disposable sterile filter membrane, other parts can be sterilized and reused, so that the experimental operation cost is greatly reduced; in addition, the whole process of subpackaging and filtering greatly reduces the human intervention, reduces the risk of polluting liquid biological products and the risk of polluting operating personnel by microorganisms, and ensures that the experimental process is time-saving, labor-saving, safe and reliable.
Drawings
Fig. 1 shows a schematic view of the structure of the present invention.
Detailed Description
As shown in fig. 1, the aseptic filtration and dispensing device for micro bottles of the present invention comprises a liquid injection part for instilling a liquid biological product into a dispensing bottle 1, the liquid injection part being provided with a liquid containing chamber inside, and a supporting part for clamping and fixing the liquid injection part; the front end liquid outlet of the liquid injection part is movably connected with a filtering part used for filtering liquid biological products, the rear end of the liquid injection part is hermetically communicated with a liquid infusion part, and the liquid inlet end of the liquid infusion part extends to a position close to the bottom of an inner cavity of a liquid containing part used for containing the liquid biological products.
Specifically, the liquid injection part is a liquid injection needle cylinder 2 made of glass material, and a sealing rubber plug 3 is arranged at the rear end of the liquid injection needle cylinder 2; the filtering part is a disposable sterile filter membrane 4 which is adapted to be arranged on a liquid outlet at the front end of the liquid injection needle cylinder 2 (the disposable sterile filter membrane 4 can adopt a filter membrane with the product number of SLGP033RB produced by Millipore manufacturers, and is conveniently connected with the liquid injection needle cylinder 2); the transfusion part consists of a transfusion hose 5 and a peristaltic pump 6 arranged on the transfusion hose 5, and the liquid outlet end of the transfusion hose 5 is hermetically communicated with a liquid containing cavity in the liquid injection needle cylinder 2 by penetrating through a sealing rubber plug 3; the liquid containing part is a beaker 7 with an open structure, and the liquid biological product contained in the beaker 7 is injected into the liquid injection needle cylinder 2 through a peristaltic pump 6. In addition, in order to clearly observe the reduction amount of the liquid biological product in the beaker 7 during the whole liquid injection process, a volume marking line 8 is provided on the outer wall of the beaker 7 in the height direction.
In order to conveniently support and fix the injection needle cylinder 2, the supporting and fixing part comprises a horizontal base 9, a longitudinal supporting rod 10 is vertically fixed on the horizontal base 9, a horizontal supporting rod 11 is connected on the longitudinal supporting rod 10 through a sliding piece, the sliding piece is a longitudinal adjusting sleeve 13 movably sleeved on the longitudinal supporting rod 10 and provided with a jacking bolt 12, and the horizontal supporting rod 11 is fixed on the outer wall of the longitudinal adjusting sleeve 13; be provided with the pipe clamp 14 that is used for the centre gripping and fixes annotating liquid cylinder 2 in the one end of horizontal strut 11, for prevent with the liquid injection cylinder 2 of glass material between take place hard contact, be provided with flexible slipmat 15 on the double-phase clamping face of pipe clamp 14, this flexible slipmat 15 not only can effectually avoid annotating liquid cylinder 2 by the clamp bits of broken glass, can also improve the frictional force when the liquid cylinder 2 is annotated in the centre gripping simultaneously.
When the device is used, the device is assembled in advance, the split charging bottle 1 is placed on the horizontal base 9 after being opened, the opening of the split charging bottle 1 is right below the liquid outlet end of the disposable sterile filter membrane 4, then a liquid biological product to be filtered is poured into the beaker 7, the peristaltic pump 6 is started, the pump speed of the peristaltic pump 6 is adjusted according to actual needs, and the liquid biological product in the beaker 7 can be sucked by the peristaltic pump 6 and is conveyed into the liquid injection needle cylinder 2 through the infusion hose 5; the liquid biological product injected into the liquid injection syringe 2 flows into the disposable sterile filter membrane 4 through the liquid outlet, and flows into the split charging bottle 1 after being filtered, thereby completing the filtering and split charging operation of the liquid biological product.

Claims (8)

1. The utility model provides a sterile filtration partial shipment device of trace bottle which characterized in that: comprises a liquid injection part of a built-in liquid containing cavity for instilling liquid biological products into a split charging bottle, and a supporting part for clamping and fixing the liquid injection part; the front end liquid outlet of the liquid injection part is movably connected with a filtering part used for filtering liquid biological products, the rear end of the liquid injection part is hermetically communicated with a liquid infusion part, and the liquid inlet end of the liquid infusion part extends to a position close to the bottom of an inner cavity of a liquid containing part used for containing the liquid biological products.
2. The micro-bottle sterile filtration and dispensing device according to claim 1, wherein: the liquid injection part is an injection needle cylinder, and a sealing rubber plug is arranged at the rear end of the injection needle cylinder.
3. The micro-bottle sterile filtration and dispensing device according to claim 2, wherein: the filtering part is a disposable sterile filter membrane which is arranged on a liquid outlet at the front end of the liquid injection needle cylinder in a matching way.
4. The micro-bottle sterile filtration and dispensing device according to claim 2, wherein: the infusion part is composed of an infusion hose and a peristaltic pump arranged on the infusion hose, and the liquid outlet end of the infusion hose penetrates through the sealing rubber plug in a sealing mode to be communicated with a liquid containing cavity in the liquid injection needle cylinder.
5. The micro-bottle sterile filtration and dispensing device according to claim 2, wherein: the supporting and fixing part comprises a horizontal base, a longitudinal supporting rod is vertically fixed on the horizontal base, the longitudinal supporting rod is connected with a horizontal supporting rod through a sliding piece, and one end of the horizontal supporting rod is provided with a pipe clamp used for clamping and fixing the liquid injection needle cylinder.
6. The micro-bottle sterile filtration and dispensing device according to claim 5, wherein: the sliding piece is a longitudinal adjusting sleeve which is movably sleeved on the longitudinal supporting rod and is provided with a jacking bolt.
7. The micro-bottle sterile filtration and dispensing device according to claim 5, wherein: and flexible anti-slip pads are arranged on the two opposite clamping surfaces of the pipe clamp.
8. The micro-bottle sterile filtration and dispensing device according to claim 1, wherein: the liquid containing part is a beaker with an open structure, and a volume marking line is arranged on the outer wall of the beaker along the height direction.
CN202020604799.6U 2020-04-21 2020-04-21 Sterile filtering and subpackaging device for micro-bottles Active CN212101946U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202020604799.6U CN212101946U (en) 2020-04-21 2020-04-21 Sterile filtering and subpackaging device for micro-bottles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202020604799.6U CN212101946U (en) 2020-04-21 2020-04-21 Sterile filtering and subpackaging device for micro-bottles

Publications (1)

Publication Number Publication Date
CN212101946U true CN212101946U (en) 2020-12-08

Family

ID=73639769

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202020604799.6U Active CN212101946U (en) 2020-04-21 2020-04-21 Sterile filtering and subpackaging device for micro-bottles

Country Status (1)

Country Link
CN (1) CN212101946U (en)

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