CN212090410U - Micro-control orbital vein quantitative blood taking, injection and analysis device - Google Patents
Micro-control orbital vein quantitative blood taking, injection and analysis device Download PDFInfo
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- CN212090410U CN212090410U CN202020040518.9U CN202020040518U CN212090410U CN 212090410 U CN212090410 U CN 212090410U CN 202020040518 U CN202020040518 U CN 202020040518U CN 212090410 U CN212090410 U CN 212090410U
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Abstract
The utility model discloses a micro-control orbital vein ration volume is got blood, injection and analytical equipment, including the three-way valve, the equal fixed connection connecting tube of three port of three-way valve, it is three the connecting tube keeps away from the one end of three-way valve fixed connection syringe needle, micro-injection pump and electric pump respectively, syringe needle annular side is served and is installed the centre gripping subassembly, the centre gripping subassembly includes the frame, the frame suit is in syringe needle annular outer end, syringe needle front end is equipped with the clamp plate, the clamp plate front end rotates the installation threaded rod, the threaded rod is established at frame inside and is extended to the frame front end, the utility model discloses rational in infrastructure has blood sampling and two kinds of functions of injection concurrently, has improved the injection accuracy.
Description
Technical Field
The utility model relates to a micro-control orbital vein quantitative blood taking, injection and analysis device, which belongs to the field of laboratory auxiliary appliances.
Background
At present, in rat/mouse animal experiments, blood sampling and medicine injection are most commonly performed by tail vein blood sampling or medicine injection, but on one hand, the training period is longer and the failure times are more; on the other hand, the mice have a large response to the disease and are often bitten. Meanwhile, a device capable of simultaneously realizing blood taking and injection is lacked at present. In addition, when a rat/mouse is injected with the medicine, the existing common injector is not accurate enough, the error is large, and no better solution to the problem exists.
Chinese patent publication CN106963397A discloses a high-efficiency blood collecting and collecting device for the bottoms of the eyes of big and small mice, which comprises a blood collecting part and a blood collecting part, wherein the blood collecting part and the blood collecting part are communicated through a hose; the blood sampling part comprises a blunt end metal tube part, the lower half part of the blood sampling part is fixedly provided with a handheld part, the handheld part comprises a central sheet and fins connected with one side or two sides of the central sheet, and anti-skidding convex points are arranged on the surfaces of the central sheet and the fins; the blood collecting part comprises an elastic plastic blood collecting tube, and the blood collecting tube comprises an upper end part with a blood collecting nozzle and a cylindrical lower end part; the blood collecting mouth is detachably and tightly connected with the end part of the hose; the upper end part is connected with a mouth cover matched with the blood collection mouth; the upper end part and the lower end part of the column shape form a detachable connection through a buckle; the lower end part of the cylinder is provided with a flat bottom, a conical bottom or a circular arc bottom; the blood collecting tube generates negative pressure during manual squeezing and hand loosening to collect blood. The blood collecting and collecting device can efficiently and conveniently collect blood, has good controllability, improves the success rate of primary blood collection and the blood collecting efficiency, is beneficial to reducing the risks of operation failure and repeated damage, and only focuses on the blood collecting function.
The Chinese patent publication CN109771075A discloses a mouse tail vein blood sampling and injection device, which comprises a mouse chamber and a platform, wherein the mouse chamber comprises a first arc plate, a second arc plate, a first transverse plate, a second transverse plate, a first vertical plate, a second vertical plate and a first slide rail, the first arc plate is vertically arranged, the first vertical plate is vertically arranged and is simultaneously connected with the side edges of the first arc plate and the first transverse plate, the second arc plate is arranged in a mirror image manner on the first arc plate, the second transverse plate is connected with the upper edge of the second arc plate, the second vertical plate is vertically arranged and is simultaneously connected with the side edges of the second arc plate and the second transverse plate, the second transverse plate is provided with the first slide rail, and the second transverse plate is movably connected with the first transverse plate through the first slide rail. The utility model discloses a carry out the space modulation with the mouse storehouse through pull slip mode, all can be well fixed to different size mice, set up lighting system simultaneously, adopt the yellow light illumination to assist, look for the tail vein more easily, improve the precision, use convenient science more. But the design aims at tail vein blood sampling and injection, and the functions of blood sampling and injection are not integrated.
Therefore, there is a need to design a micro-control orbital vein quantitative blood-taking, injection and analysis device to solve the problems in the prior art.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a little accuse orbit vein ration volume is got blood, injection and analytical equipment to solve the device that can realize getting blood and injection simultaneously that the lack of proposing in the above-mentioned background art, and the syringe commonly used is accurate inadequately, the great problem of error, the utility model discloses it is rational in infrastructure, have blood sampling and two kinds of functions of injection concurrently, improved the injection accuracy.
In order to achieve the above purpose, the present invention is realized by the following technical solution: the utility model provides a micro-control orbital vein ration volume blood taking, injection and analytical equipment, includes the three-way valve, the equal fixed connection connecting tube of three port of three-way valve, it is three the connecting tube is kept away from the one end of three-way valve and is fixed connection syringe needle, micro-syringe pump and electric pump respectively, the annular side of syringe needle is served and is installed the centre gripping subassembly.
Furthermore, a micro-fluidic chip is arranged between the connecting conduit and the electric pump, and the electric pump is a quantitative pump.
Further, the centre gripping subassembly includes the frame, the frame suit is in syringe needle annular outer end, the syringe needle front end is equipped with the clamp plate, the clamp plate front end rotates the installation threaded rod, the threaded rod is established inside the frame and is extended to the frame front end.
Further, a handle is fixed at the front end of the threaded rod, and an arc-shaped rubber pad is fixed at the contact position of the pressing plate and the injection needle.
Further, the centre gripping subassembly still includes two carriage, two both ends about the carriage symmetry is fixed at the frame, two inside grip block and the grip block of all being equipped with of carriage both ends are all extended from the carriage is inside, the carriage is connected with the grip block through the pivot, the equal fixed spring in both ends about the syringe needle, two the spring respectively with two grip block fixed connection, the spring is established in the carriage left side.
Further, the clamping plate comprises a clamping portion and a holding portion, the clamping portion is arranged at the right end of the holding portion, a rubber cushion is fixed to one end, close to the position of the needle head of the injection needle, of the clamping portion, and the holding portion is fixedly connected with the spring.
Further, the frame includes left frame and right frame, right frame is fixed at left frame right-hand member, the V-arrangement groove is seted up to right frame left end, left frame passes through threaded connection with the threaded rod.
The utility model has the advantages that: the utility model discloses a micro-control orbit vein ration gets blood, injection and analytical equipment, the three-way valve passes through connecting tube respectively with the micro-injection pump, electric pump and syringe needle are connected respectively, realize the injection function when micro-injection pump and syringe needle put through, realized the blood sampling function when electric pump and syringe needle put through, the convenience of use has been improved, and before syringe needle inserts the mouse internally, press two grip blocks, make the clamping part of grip block expand, after inserting the mouse internally with the syringe needle, loosen the grip block, utilize the elastic force of spring to act on, make the grip block carry out the centre gripping with the head of mouse, the realization is fixed syringe needle and mouse, avoid taking place relative movement between grip block and the mouse head in the operation process, the smooth and easy nature of experiment has been improved.
Drawings
The above advantages of the present invention will become more apparent and more readily appreciated from the detailed description taken in conjunction with the following drawings, which are given by way of illustration only and do not limit the present invention, and in which:
fig. 1 is a schematic structural view of a micro-control orbital vein quantitative blood-taking, injection and analysis device of the present invention;
FIG. 2 is a front view of a clamping assembly of the micro-control orbital vein quantitative blood-taking, injection and analysis device of the present invention;
FIG. 3 is a right side view of a clamping assembly of a micro-controlled orbital vein quantitative blood-sampling, injection and analysis device of the present invention;
fig. 4 is a schematic diagram of a frame in the micro-control orbital vein quantitative blood-taking, injection and analysis device of the present invention.
In the figure:
1-injection needle, 2-connecting conduit, 3-three-way valve, 4-micro-injection pump, 5-clamping component, 6-electric pump, 51-clamping plate, 52-rubber soft cushion, 53-supporting frame, 54-spring, 55-frame, 56-threaded rod, 57-pressing plate, 61-micro-fluidic chip, 551-left frame, 552-right frame
Detailed Description
The micro-controlled orbital vein quantitative blood-taking, injection and analysis device of the present application is described in detail with reference to the following specific embodiments and the accompanying drawings.
The embodiments described herein are specific embodiments of the present invention, and are intended to be illustrative of the concepts of the present invention, which are intended to be illustrative and exemplary, and should not be construed as limiting the scope of the embodiments of the present invention. In addition to the embodiments described herein, those skilled in the art will be able to employ other technical solutions which are obvious based on the disclosure of the claims and the specification of the present application, and these technical solutions include technical solutions which make any obvious replacement or modification for the embodiments described herein.
The drawings in the present specification are schematic views to assist in explaining the concept of the present invention, and schematically show the shapes of the respective portions and the mutual relationships thereof. Note that, in order to clearly show the structure of each component of the embodiment of the present invention, the same reference numerals are used to denote the same parts.
Referring to fig. 1-4, the present invention provides a technical solution: a micro-control orbital vein quantitative blood measuring, injection and analysis device comprises a three-way valve 3, wherein the three-way valve 3 realizes the connection function and is convenient for adjusting the connection state, three ports of the three-way valve 3 are all fixedly connected with a connecting conduit 2, the connecting conduit 2 is formed by rubber or plastics, one end of each connecting conduit 2 far away from the three-way valve 3 is respectively and fixedly connected with an injection needle 1, a micro-injection pump 4 and an electric pump 6, the injection needle 1 is formed by a glass capillary tube with the inner wall treated by heparin and injector needles of different models, a clamping component 5 is arranged on the annular side end of the injection needle 1, specifically, the three-way valve 3 is respectively connected with the micro-injection pump 4, the electric pump 6 and the injection needle 1 through the connecting conduit 2, when a valve rod of the three-way valve 3 is operated to lead the micro-injection pump 4 to be connected with the injection needle 1, the injection function is realized, wherein the, the precision injection is dosed, has improved the accuracy of injection, and operation three-way valve 3 makes electric pump 6 and syringe needle 1 switch-on, has realized the blood sampling function, has realized two kinds of functions of blood sampling and injection and can change through simple operation between two kinds of functions, has improved the convenience of use.
The micro-fluidic chip 61 is arranged between the connecting conduit 2 and the electric pump 6, the electric pump 6 is a quantitative pump, the electric pump 6 provides controllable suction through electric negative pressure, so that the sucked blood continuously, uniformly and slowly passes through the micro-fluidic chip 61 for analysis, and the micro-fluidic chip 61 is utilized to realize routine blood analysis and biochemical blood analysis.
The clamping component 5 comprises a frame 55, the frame 55 is sleeved at the annular outer end of the injection needle 1, a pressing plate 57 is arranged at the front end of the injection needle 1, a threaded rod 56 is arranged at the front end of the pressing plate 57 through a bearing, the threaded rod 56 is arranged in the frame 55 and extends to the front end of the frame 55, specifically, the injection needle 1 is arranged in the frame 55, the outer end surface of the injection needle 1 is contacted with the right side wall of the frame 55, then a worker rotates the threaded rod 56, as the threaded rod 56 is connected with the frame 55 through a thread, the threaded rod 56 rotates and moves right at the same time, the threaded rod 56 moves right to drive the pressing plate 57 to move right, when the pressing plate 57 moves right to be contacted with the outer end surface of the injection needle 1 and tightly presses the injection needle 1 in the frame 55, the threaded rod 56 stops rotating, the clamping component 5 is fixedly, thereby facilitating the clamping and fixing of 1 with different pipe diameters by 55, 56 and 57.
The handle is fixed at the front end of the threaded rod 56, the arc-shaped rubber pad is fixed at the contact position of the pressing plate 57 and the injection needle head 1, the threaded rod 56 is rotated by rotating the handle, the buffer function is realized by the design of the arc-shaped rubber pad, and the injection needle head 1 is protected conveniently.
The clamping assembly 5 further comprises two supporting frames 53, the two supporting frames 53 are symmetrically fixed at the upper end and the lower end of the frame 55, the clamping plate 51 is arranged inside the two supporting frames 53, the left end and the right end of the clamping plate 51 extend out of the supporting frames 53, the supporting frames 53 are connected with the clamping plate 51 through rotating shafts, springs 54 are fixed at the upper end and the lower end of the injection needle 1 respectively, the two springs 54 are fixedly connected with the two clamping plates 51 respectively, the springs 54 are arranged on the left side of the supporting frames 53, and the clamping plates 51 can rotate around the supporting frames 53.
The clamping plate 51 comprises a clamping portion and a holding portion, the clamping portion is arranged at the right end of the holding portion, a rubber cushion 52 is fixed at one end, close to the needle position of the injection needle 1, of the clamping portion, the holding portion is fixedly connected with a spring 54, the clamping portion is convenient for clamping the head of a mouse, and a person can press the clamping plate 51 conveniently.
The working principle is as follows: when a mouse is taken as an experimental object, a person firstly connects the micro-injection pump 4 with a pipeline filled with injection, connects the electric pump 6 with a pipeline to be loaded with blood, then a sterile sheet is laid on a laboratory table after disinfection, then the skin of the back neck of the mouse is grabbed by the left thumb and the index finger, the skin is lightly pressed on a table top, the inner canthus is disinfected by alcohol, the hand-held parts of the two clamping plates 51 are respectively pressed by the right thumb and the index finger to rotate the clamping plates 51, the two clamping parts of the clamping plates 51 respectively move outwards to proper positions, at the moment, the spring 54 is compressed and generates elasticity, meanwhile, the other fingers of the right hand grasp the far end of the needle head of the injection needle head 1, then the cutting part of the tip of the needle head is lightly inserted into the eye socket of the mouse close to the nasal bridge to pierce the inner canthus vein, then the person loosens the clamping plates 51, the clamping plates 51 rotate around the supporting frame 53 under the action of the elasticity of the, the clamping parts of the two clamping plates 51 move towards opposite directions, then the clamping parts of the two clamping plates 51 are respectively clamped at the two ends of the head of the mouse to realize clamping and fixing of the head of the mouse, the rubber cushion 52 is contacted with the head of the mouse to realize a buffer function, the design improves the connection tightness between the injection needle 1 and the mouse, avoids the needle head part of the injection needle 1 from falling off from the head of the mouse in the experimental process, when in blood taking operation, the electric pump 6 is opened to set the required blood volume, the three-way valve 3 is changed into a state that the electric pump 6 is communicated with the injection needle 1 to start the blood taking process, when in the injection state, the injection is filled in the micro-injection pump 4 in advance and the injection volume and speed are set, then the three-way valve 3 is changed into a state that the micro-injection pump 4 is communicated with the injection needle 1 to finish the injection, and the injection precision of the micro-injection pump 4 is improved, this design has blood sampling and two kinds of functions of injection concurrently, and just can change through simple operation between two kinds of functions, has improved and has used the flexibility.
The present invention is not limited to the above embodiments, and any person can obtain other products in various forms without departing from the scope of the present invention, but any change in shape or structure is included in the technical solution that is the same as or similar to the present invention.
Claims (7)
1. The utility model provides a micro-control orbital vein ration volume blood taking, injection and analytical equipment which characterized in that: including the three-way valve, the equal fixed connection connecting tube in three port of three-way valve, it is three the connecting tube is kept away from the one end of three-way valve and is fixed connection syringe needle, micro-syringe pump and electric pump respectively, the installation centre gripping subassembly is served to syringe needle annular side.
2. The micro-controlled orbital vein quantitative blood taking, injection and analysis device according to claim 1, wherein: and a micro-fluidic chip is arranged between the connecting conduit and the electric pump, and the electric pump is a quantitative pump.
3. The micro-controlled orbital vein quantitative blood taking, injection and analysis device according to claim 1, wherein: the centre gripping subassembly includes the frame, the frame suit is in syringe needle annular outer end, the syringe needle front end is equipped with the clamp plate, the clamp plate front end rotates the installation threaded rod, the threaded rod is established inside the frame and is extended to the frame front end.
4. The micro-controlled orbital vein quantitative blood taking, injection and analysis device according to claim 3, wherein: the handle is fixed at the front end of the threaded rod, and the arc-shaped rubber pad is fixed at the contact position of the pressing plate and the injection needle.
5. The micro-controlled orbital vein quantitative blood taking, injection and analysis device according to claim 1 or 4, wherein: the clamping assembly further comprises two supporting frames, the two supporting frames are symmetrically fixed at the upper end and the lower end of the frame, the two supporting frames are internally provided with clamping plates, the left end and the right end of each clamping plate extend out of the supporting frames, the supporting frames are connected with the clamping plates through rotating shafts, springs are fixed at the upper end and the lower end of the injection needle respectively and are fixedly connected with the two clamping plates, and the springs are arranged on the left side of the supporting frames.
6. The micro-controlled orbital vein quantitative blood taking, injection and analysis device according to claim 5, wherein: the grip block includes clamping part and handle, the clamping part is established at the handle right-hand member, the clamping part is close to the fixed rubber cushion of one end of syringe needle position, handle and spring fixed connection.
7. The micro-controlled orbital vein quantitative blood taking, injection and analysis device according to claim 3, wherein: the frame includes left frame and right frame, right frame is fixed at left frame right-hand member, the V-arrangement groove is seted up to right frame left end, left side frame passes through threaded connection with the threaded rod.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020040518.9U CN212090410U (en) | 2020-01-09 | 2020-01-09 | Micro-control orbital vein quantitative blood taking, injection and analysis device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202020040518.9U CN212090410U (en) | 2020-01-09 | 2020-01-09 | Micro-control orbital vein quantitative blood taking, injection and analysis device |
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| CN212090410U true CN212090410U (en) | 2020-12-08 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112618819A (en) * | 2021-01-07 | 2021-04-09 | 上海药明康德新药开发有限公司 | Novel automatic blood sampling instrument and blood sampling method design |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112618819A (en) * | 2021-01-07 | 2021-04-09 | 上海药明康德新药开发有限公司 | Novel automatic blood sampling instrument and blood sampling method design |
| CN112618819B (en) * | 2021-01-07 | 2022-02-22 | 上海药明康德新药开发有限公司 | Novel automatic blood sampling instrument and blood sampling method design |
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