CN211896741U - Preparation device for apolipoprotein B - Google Patents
Preparation device for apolipoprotein B Download PDFInfo
- Publication number
- CN211896741U CN211896741U CN201922235696.7U CN201922235696U CN211896741U CN 211896741 U CN211896741 U CN 211896741U CN 201922235696 U CN201922235696 U CN 201922235696U CN 211896741 U CN211896741 U CN 211896741U
- Authority
- CN
- China
- Prior art keywords
- centrifugal
- apolipoprotein
- rotary disk
- upside
- screw rod
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 101710095342 Apolipoprotein B Proteins 0.000 title claims abstract description 16
- 102100040202 Apolipoprotein B-100 Human genes 0.000 title claims abstract description 16
- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- 239000000463 material Substances 0.000 claims description 3
- 238000009472 formulation Methods 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 238000005119 centrifugation Methods 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 3
- 102000004169 proteins and genes Human genes 0.000 abstract description 2
- 108090000623 proteins and genes Proteins 0.000 abstract description 2
- 102000018616 Apolipoproteins B Human genes 0.000 description 4
- 108010027006 Apolipoproteins B Proteins 0.000 description 4
- 108010028554 LDL Cholesterol Proteins 0.000 description 4
- 208000029078 coronary artery disease Diseases 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 238000005199 ultracentrifugation Methods 0.000 description 2
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 101710172711 Structural protein Proteins 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
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- Centrifugal Separators (AREA)
Abstract
The utility model discloses a preparation device for apolipoprotein B, relate to the protein preparation field, only be applicable to specific centrifugal test tube to current test tube centrifugal device, application scope is limited, can increase the problem of hospital's economic burden, the scheme as follows now is proposed, it includes the organism, the upside of organism articulates there is the lid, inside be equipped with centrifugal cavity, centrifugal motor is installed to the bottom of centrifugal cavity, centrifugal motor's output shaft has the rotary disk, centrifugal frame is installed to the upside of rotary disk, a plurality of centrifugal tube holes have been seted up on the centrifugal frame, the locating hole that corresponds with centrifugal tube hole is seted up to the upper surface of rotary disk, the upside of centrifugal frame is equipped with the clamp plate, the clamp plate passes through connecting device and installs on the lid, connecting device includes the handle, the screw rod, plectane and connecting piece. The utility model is suitable for a centrifugation of the centrifugal test tube in the certain diameter within range alleviates the use cost of hospital, can guarantee the safety of centrifugal test tube in centrifugal process simultaneously.
Description
Technical Field
The utility model relates to a protein preparation field especially relates to a preparation device for apolipoprotein B.
Background
ApoB is synthesized by the liver, is the main structural protein of low-density lipoprotein cholesterol (LDL-CHOL), accounts for about 97 percent of the total protein content of the LDL-CHOL, can directly reflect the level of the LDL-CHOL by measuring ApoB, and the increase of the level of the ApoB is a risk factor of coronary heart disease and is positively correlated with the incidence rate of atherosclerosis and coronary heart disease, namely the increase of the level of the ApoB has higher risk of the occurrence of the coronary heart disease.
Apolipoprotein B in the preparation process, serum needs to be subjected to ultracentrifugation treatment to extract apolipoprotein B, the existing ultracentrifugation device can only be used for centrifugation of a centrifugal test tube with a specific size, if a centrifugal test tube with a slightly smaller diameter is placed, the test tube is cracked due to shaking in the centrifugation process, the application range is limited, and hospitals need to purchase various centrifugal devices to meet different use requirements, so that the cost is high, and therefore, a preparation device for apolipoprotein B is designed to solve the problems.
SUMMERY OF THE UTILITY MODEL
The utility model provides a preparation device for apolipoprotein B has solved current test tube centrifugal device and has only been applicable to specific centrifugal test tube, and application scope is limited, can increase the problem of hospital's economic burden.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
the utility model provides a preparation device for apolipoprotein B, includes the organism, the upside of organism articulates there is the lid, and inside be equipped with centrifugal cavity, centrifugal motor is installed to the bottom of centrifugal cavity, centrifugal motor's output shaft has the rotary disk, centrifugal frame is installed to the upside of rotary disk, a plurality of centrifugal tube holes have been seted up on the centrifugal frame, and the locating hole that corresponds with centrifugal tube hole is seted up to the upper surface of rotary disk, and the upside of centrifugal frame is equipped with the clamp plate, the clamp plate passes through connecting device and installs on the lid, connecting device includes handle, screw rod, plectane and connecting piece, and the screw rod passes through the screw thread to be connected with the lid, and the one end that the lid was passed to the upper end of screw rod links to each other with the handle is fixed, and the lower extreme of screw rod links to each.
Preferably, a rubber ring is arranged in the hole of the centrifugal pipe, and the inner wall of the rubber ring is in an inverted cone shape.
Preferably, a cushion pad is arranged in the positioning hole and is made of a rubber material.
Preferably, an indication ruler is fixedly installed on the upper side of the pressing plate, and the upper end of the indication ruler penetrates through the cover body.
Preferably, the two sides of the rotating disc are provided with first retaining rings mounted on the inner wall of the machine body.
Preferably, the upper part of the centrifugal frame is provided with a second retaining ring mounted on the inner wall of the machine body.
Compared with the prior art, the beneficial effects of the utility model are that:
1. the utility model is suitable for the centrifugation of the centrifugal test tube within a certain diameter range, and simultaneously, the pressing of the centrifugal test tube is realized by controlling the height of the pressing plate, so that the centrifugal test tube can be prevented from shaking up, down, left and right in the centrifugation process, the centrifugal safety can be ensured while the application range is enlarged, and the use cost of the hospital is reduced;
2. the specific descending height of the middle pressure plate can be checked and controlled through the indicating ruler, so that the centrifugal test tube can be prevented from being pressed down or damaged, and the safety is high;
3. the utility model discloses well first retaining ring and the setting of second retaining ring can guarantee the steady rotation of rotary disk and centrifugal frame, avoid and the organism between wearing and tearing improve life.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a schematic structural diagram of the connection device of the present invention.
Fig. 3 is a schematic structural view of the rotating disk of the present invention.
Fig. 4 is a schematic structural view of the centrifugal frame of the present invention.
Reference numbers in the figures: 1 machine body, 2 centrifugal motors, 3 rotating disks, 4 centrifugal frames, 5 centrifugal pipe holes, 6 positioning holes, 7 pressing plates, 8 handles, 9 screw rods, 10 round plates, 11 connecting pieces, 12 cover bodies, 13 rubber rings, 14 rubber buffer cushions, 15 indicating rules, 16 first retaining rings and 17 second retaining rings.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.
Referring to fig. 1-4, a preparation device for apolipoprotein B, comprising a body 1, a cover 12 hinged on the upper side of the body 1, a centrifugal cavity arranged inside the body, a centrifugal motor 2 mounted at the bottom of the centrifugal cavity, a rotary disk 3 connected to the output shaft of the centrifugal motor 2, first retaining rings 16 mounted on the inner wall of the body 1 on the two sides of the rotary disk 3, a centrifugal frame 4 mounted on the upper side of the rotary disk 3, a second retaining ring 17 mounted on the inner wall of the body 1 on the upper portion of the centrifugal frame 4, a plurality of centrifugal tube holes 5 formed on the centrifugal frame 4, a rubber ring 13 arranged in the centrifugal tube holes 5, and an inner wall of the rubber ring 13 being in a reverse taper shape, a positioning hole 6 corresponding to the centrifugal tube hole 5 formed on the upper surface of the rotary disk 3, a cushion 14 arranged in the positioning hole 6, the cushion 14 made of rubber material, the pressing plate 7 is installed on the cover body 12 through a connecting device, the connecting device comprises a handle 8, a screw rod 9, a circular plate 10 and a connecting piece 11, the screw rod 9 is connected with the cover body 12 through threads, one end of the upper end of the screw rod 9, which penetrates through the cover body 12, is fixedly connected with the handle 8, the lower end of the screw rod 9 is fixedly connected with the circular plate 10, the circular plate 10 is rotatably connected with the connecting piece 11 through a bearing, the connecting piece 11 is fixedly connected with the pressing plate 7, an indicating ruler 15 is fixedly installed on the upper side of the pressing plate 7, and the upper end of the.
The working principle is as follows: when in use, the centrifuge tube with serum is sealed and put into the centrifuge tube hole 5, the rubber ring 13 is arranged, the centrifuge tube is suitable for centrifuge tubes with diameters within a certain range, the application range is expanded, after the centrifuge tube is put into the centrifuge tube, the cover body 12 is covered on the machine body 1, the handle 8 can be rotated according to actual conditions, the height of the pressing plate 7 is adjusted by utilizing the matching of the screw rod 9 and the screw thread, so that the centrifuge tubes are pressed, the specific descending height can be checked and controlled through the indicating ruler 15, the pressing plate 7 presses the centrifuge tubes to avoid shaking in the centrifugal process, then the centrifuge motor 2 is started to drive the centrifuge tube on the rotating plate 3 and the centrifuge frame 4 to rotate at high speed, the centrifugal equipment is purchased by a hospital, the centrifugal requirements of various centrifuge tubes can be met, certain economic burden is reduced, in addition, in the centrifugal process, the positioning holes 6 on the rotating plate 3 and the rubber cushion 14 in the positioning holes 6 are arranged, can further guarantee the firm of centrifugal test tube position, improve the safety of centrifugal test tube, guarantee centrifugal normal clear.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and to simplify the description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.
The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.
Claims (6)
1. The utility model provides a preparation device for apolipoprotein B, includes organism (1), its characterized in that, the upside of organism (1) articulates there is lid (12), and the inside of being equipped with centrifugal cavity, centrifugal motor (2) are installed to the bottom of centrifugal cavity, the output shaft of centrifugal motor (2) has rotary disk (3), centrifugal rack (4) are installed to the upside of rotary disk (3), a plurality of centrifugal tube hole (5) have been seted up on centrifugal rack (4), and locating hole (6) that correspond with centrifugal tube hole (5) have been seted up to the upper surface of rotary disk (3), and the upside of centrifugal rack (4) is equipped with clamp plate (7), clamp plate (7) are installed on lid (12) through connecting device, connecting device includes handle (8), screw rod (9), plectane (10) and connecting piece (11), and screw rod (9) are connected with lid (12) through the screw thread, the upper end of the screw rod (9) penetrates through one end of the cover body (12) to be fixedly connected with the handle (8), the lower end of the screw rod (9) is fixedly connected with the circular plate (10), the circular plate (10) is rotatably connected with the connecting piece (11) through a bearing, and the connecting piece (11) is fixedly connected with the pressing plate (7).
2. The preparation device for apolipoprotein B according to claim 1, wherein the rubber ring (13) is provided in the centrifuge tube hole (5), and an inner wall of the rubber ring (13) is in an inverted cone shape.
3. The formulation set for apolipoprotein B according to claim 1, wherein a cushion (14) is disposed within the positioning hole (6), the cushion (14) being made of a rubber material.
4. The formulation set for apolipoprotein B according to claim 1, wherein an indication ruler (15) is fixedly installed at an upper side of the pressing plate (7), and an upper end of the indication ruler (15) passes through the cap body (12).
5. The formulation set for apolipoprotein B according to claim 1, wherein the rotary disk (3) is provided at both sides with first retaining rings (16) mounted on the inner wall of the body (1).
6. The formulation set for apolipoprotein B according to claim 1, wherein the upper portion of the centrifuge basket (4) is provided with a second retaining ring (17) mounted on the inner wall of the body (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922235696.7U CN211896741U (en) | 2019-12-13 | 2019-12-13 | Preparation device for apolipoprotein B |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922235696.7U CN211896741U (en) | 2019-12-13 | 2019-12-13 | Preparation device for apolipoprotein B |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211896741U true CN211896741U (en) | 2020-11-10 |
Family
ID=73292931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201922235696.7U Expired - Fee Related CN211896741U (en) | 2019-12-13 | 2019-12-13 | Preparation device for apolipoprotein B |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN211896741U (en) |
-
2019
- 2019-12-13 CN CN201922235696.7U patent/CN211896741U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20201110 |