CN211894410U - Sodium bicarbonate injection plastic packaging system with leakage indicating function - Google Patents

Sodium bicarbonate injection plastic packaging system with leakage indicating function Download PDF

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CN211894410U
CN211894410U CN201922400226.1U CN201922400226U CN211894410U CN 211894410 U CN211894410 U CN 211894410U CN 201922400226 U CN201922400226 U CN 201922400226U CN 211894410 U CN211894410 U CN 211894410U
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ampoule
sodium bicarbonate
indicator
bicarbonate injection
plastic packaging
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周芸芸
李正艳
马敬昊
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China Otsuka Pharmaceutical Co Ltd
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China Otsuka Pharmaceutical Co Ltd
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Abstract

The utility model relates to a sodium bicarbonate injection plastic packaging system of function is leaked in area instruction, locate the outside extranal packing of ampoule including ampoule, the sealed cowling that is equipped with the sodium bicarbonate injection, be filled with protective gas between ampoule and the extranal packing, still be equipped with the indicator instruction sign that is used for instructing whether the extranal packing leaks between ampoule and the extranal packing, the indicator instruction sign outside is equipped with the protection film, the ampoule is including the handle portion, the cap portion, splashproof liquid bottle oral area, the body portion that connect gradually. The utility model discloses can give normal instruction when the concentration change of protective gas, or the leakage of extranal packing to can prevent the interference of vapor, oxygen and carbon dioxide gas in the external world.

Description

Sodium bicarbonate injection plastic packaging system with leakage indicating function
Technical Field
The utility model belongs to the technical field of pharmaceutical packaging, especially, relate to a sodium bicarbonate injection plastic packaging system of function is leaked in area instruction.
Background
For the sodium bicarbonate injection, the sodium bicarbonate injection is easy to decompose into sodium carbonate, carbon dioxide and water during the storage and use processes due to unstable chemical properties of sodium bicarbonate, so that the pH value changes, which may cause adverse reactions in human bodies, while the sodium bicarbonate injection is alkaline, which may cause glass desquamation when filled in glass ampoules, so that glass packages and plastic packages with poor gas barrier effect may generate potential risks.
Therefore, in view of these problems, it is important to provide a plastic packaging system for sodium bicarbonate injection with leakage indication function, which can give a normal indication when the concentration of the protective gas changes or the leakage of the outer package occurs, and can prevent the interference of water vapor, oxygen and carbon dioxide gas in the outside, and it is important to realize the plastic packaging system.
SUMMERY OF THE UTILITY MODEL
The utility model discloses a solve the problem that exists among the above-mentioned prior art, provide one kind can give normal instruction when the concentration change of protective gas, or the leakage of extranal packing to can prevent that the area of the interference of external vapor, oxygen and carbon dioxide gas from instructing the sodium bicarbonate injection plastic packaging system who leaks the function.
The utility model discloses a solve the technical scheme who takes of this problem and be:
the utility model provides a sodium bicarbonate injection plastic packaging system of function is leaked in area instruction, locates the outside extranal packing of ampoule including ampoule, the sealed cowling that is equipped with sodium bicarbonate injection, be filled with protective gas between ampoule and the extranal packing, still be equipped with the indicator instruction sign that is used for instructing whether the extranal packing leaks between ampoule and the extranal packing, the indicator instruction sign outside is equipped with the protection film, the ampoule is including the handle portion, the sealed cap portion, splashproof liquid bottle oral area, the body portion that connect gradually.
Preferably, the extranal packing is the outer packing bag of high resistant barrier property, and its inside closed storage cavity that supplies the ampoule to deposit that forms, the material structure of extranal packing is composite construction, and its material structure is formed for two kinds at least complex in high resistant barrier polyester film, biaxial stretching nylon film, the curtain coating polypropylene film.
Further preferably, the indicator label comprises virgin pulp, bromothymol blue and sodium bicarbonate.
More preferably, the protective gas is carbon dioxide gas, the outer package is filled with 40% to 60% of the carbon dioxide gas, and the indicator label is colored differently according to the concentration of the carbon dioxide gas in the outer package and the sealing/leakage state of the outer package.
Further preferably, the ampoule is a polypropylene ampoule, scale marks are arranged on the outer side of the ampoule, and a label is attached to the outer side of the ampoule.
Further preferably, the bottle body part and the cap sealing part are connected into a closed integrated structure through an anti-splash liquid bottle mouth part, a twisting groove is formed in the middle of the anti-splash liquid bottle mouth part in a retracted mode, and the thickness of the twisting groove is the thinnest.
Preferably, the indicator label is free and exists in the closed storage cavity, and the protective film is of a film bag structure wrapped on the outer side of the indicator label.
Further preferably, the indicator is arranged on the outer side of the label, and the label comprises a composite film layer, a paper layer, a printed paper layer and an adhesive layer which are sequentially overlapped.
Further preferably, the indicator label is welded on the outer surface of the laminating layer, and the protective film is formed on the outer side of the indicator label, so that the indicator label is hermetically wrapped between the protective film and the laminating layer.
More preferably, the protective film and the compound film layer are OPP/CPP composite films respectively.
The utility model has the advantages and positive effects that:
1. the utility model discloses in, be equipped with the indicator that is used for instructing whether extranal packing is leaked between ampoule and extranal packing and instruct the sign, can give normal instruction when the concentration change of protective gas or the leakage of extranal packing, in time feed back to people, instruct through the look state, more directly perceived, striking, simple and convenient.
2. The utility model discloses in, only need through rotatory handle portion, the groove play of twisting off of splashproof liquid bottle oral area can be twisted off by light, and rotatory twisting off still can prevent that the injection from spattering outward, and the syringe needle can insert and extract sodium bicarbonate injection in the bottleneck, need not with the help of other instruments, and the hand is twisted and can be opened, convenient operation, security height.
3. The utility model discloses in, two kinds at least complex in the extranal packing is high resistant barrier polyester film, biaxial stretching nylon film, curtain coating polypropylene film form, and intensity is high, can effectively separate vapor, oxygen and carbon dioxide gas to the guarantee seals the closed condition who deposits the cavity, prevents in the external world interference of vapor, oxygen and carbon dioxide gas.
4. The utility model discloses in, indicator instruction is signed accessible protection film and is independently packed and place in the extranal packing in, can give normal instruction when the concentration change of protective gas, or the leakage of extranal packing, in time feeds back to people, and the protection film can prevent that indicator instruction from signing interior moisture loss, give off and cause the indicator inefficacy.
5. The utility model discloses in, indicator instructs to sign still can adopt the welding form to compound to the label on, can give normal instruction when the outer packing leaks, has reduced the link of packing into of single indicator, and production speed is unanimous with labeller speed to reach the purpose that improves production efficiency.
Drawings
The technical solution of the present invention will be described in further detail with reference to the accompanying drawings and examples, but it should be understood that these drawings are designed for illustrative purposes only and thus are not intended to limit the scope of the present invention. Furthermore, unless otherwise indicated, the drawings are intended to be illustrative of the structural configurations described herein and are not necessarily drawn to scale.
FIG. 1 is a schematic structural view of example 1;
FIG. 2 is a schematic cross-sectional view of the indicator tab of FIG. 1;
FIG. 3 is a schematic structural view of example 2;
FIG. 4 is a schematic cross-sectional view of the label of FIG. 3;
fig. 5 is a schematic structural view of an ampoule bottle.
In the figure: 1. ampoule bottle, 2. external package, 3. indicator label, 4. protective film, 5. handle part, 6. cap sealing part, 7. mouth part of splash-proof bottle, 71. twist-off groove, 8. bottle body part, 9. sealed storage cavity, 10. scale mark, 11. label, 12. complex film layer, 13. paper layer and printed paper layer, 14. non-drying glue layer.
Detailed Description
First, it should be noted that the specific structures, features, advantages, etc. of the present invention will be described in detail below by way of example, but all the descriptions are only for illustrative purpose and should not be construed as forming any limitation to the present invention. Furthermore, any single feature described or implicit in any embodiment or any single feature shown or implicit in any drawing may still be combined or subtracted between any of the features (or equivalents thereof) to obtain still further embodiments of the invention that may not be directly mentioned herein. In addition, for the sake of simplicity, the same or similar features may be indicated in only one place in the same drawing.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "disposed," "connected," "fixed," "screwed" and the like are to be construed broadly, e.g., as meaning fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through an intermediate medium, and may be connected through the inside of two elements or in an interaction relationship between two elements, unless otherwise specifically defined, and the specific meaning of the above terms in the present invention will be understood by those skilled in the art according to specific situations. The present invention will be described in detail with reference to fig. 1 to 5.
Example 1:
as shown in fig. 1, 2, 5, a sodium bicarbonate injection plastic packaging system of function is leaked in area instruction, locate 1 outside extranal packing 2 of ampoule including ampoule 1, the sealed cowling that is equipped with sodium bicarbonate injection, be filled with protective gas between ampoule 1 and the extranal packing 2, still be equipped with the indicator that is used for instructing whether extranal packing 2 leaks between ampoule 1 and the extranal packing 2 and instruct signing 3, the indicator instructs 3 outsides to sign and is equipped with protection film 4, ampoule 1 is including handle portion 5, sealing cap portion 6, splashproof liquid bottle oral area portion 7, the body portion 8 that connects gradually.
The working principle is as follows: in the technical scheme, the ampoule bottle 1 is filled with the sodium bicarbonate injection, the sodium bicarbonate injection is packaged in the outer package 2 with high barrier property after being sterilized at high temperature, and the sodium bicarbonate injection is easily decomposed into sodium carbonate, carbon dioxide and water in the processes of storage and use due to unstable chemical property of the sodium bicarbonate, so that the pH value is changed, adverse reaction is possibly caused when the sodium bicarbonate injection is input into a human body, and potential risk is possibly caused, therefore, the outer package 2 is hermetically covered outside the ampoule bottle 1, and protective gas with a certain concentration is filled between the outer package 2 and the ampoule bottle 1, so that the balance state of the sodium bicarbonate injection is realized; however, in the transportation process, carbon dioxide gas may be lost due to tiny breakage of the outer package 2, and the balance function of protecting the sodium bicarbonate injection cannot be achieved, namely, when the outer package 2 leaks, the protective gas leaks along with the leakage, if the risk is found to exist in short time, an indicator indicating label 3 for indicating whether the outer package 2 leaks is arranged between the ampoule bottle 1 and the outer package 2, so that normal indication can be given when the concentration of the protective gas changes or the leakage of the outer package, the indication is timely fed back to people, and the indication is more visual, striking and simple through the color change state; the protective film 4 is arranged on the outer side of the indicator label 3, so that the indicator can be prevented from losing and diffusing water in the indicator label 3 to cause indicator failure; ampoule 1 is including the handle portion 5 that connects gradually, sealing cap portion 6, splashproof liquid bottle oral area 7, body portion 8, sodium bicarbonate injection splendid attire is in body portion 8, when needs use, only need through rotatory handle portion 5, splashproof liquid bottle oral area 7 is twisted off, rotatory twist off still can prevent that the injection from spattering outward, the syringe needle can insert and extract sodium bicarbonate injection in the bottleneck, need not with the help of other instruments, the hand is twisted and can be opened, high safety and convenient operation.
Further, still consider in this embodiment, extranal packing 2 is the outer packing bag of high separation performance, and cavity 9 is deposited to its inside closed that supplies the ampoule to deposit that forms, extranal packing 2's material structure is composite construction, and its material structure is formed for two at least kinds of complex in high separation polyester film, biaxial stretching nylon film, the curtain coating polypropylene film, and extranal packing 2 intensity is high, can effectively separate vapor, oxygen and carbon dioxide gas to the guarantee seals the closed condition of depositing cavity 9, prevents in the external interference of vapor, oxygen and carbon dioxide gas.
Still further, it is also considered in this embodiment that the indicator label 3 contains virgin pulp, bromothymol blue, and sodium bicarbonate.
Further, it is also considered in this embodiment that the protective gas is carbon dioxide gas, the outer package 2 is filled with 40% to 60% of carbon dioxide gas, and the indicator label 3 displays different colors according to the concentration of carbon dioxide gas in the outer package 2 and the sealing/leakage state of the outer package.
The principle of color change of the indicator label 3 is as follows:
Figure BDA0002341243960000051
indicator label 3 can show different colours according to the concentration of protection carbon dioxide in extranal packing 2, or the protection inefficacy/effective state of extranal packing to indicate whether extranal packing 2 has the leakage, promptly, according to indicator label 3 colour judgement, carbon dioxide concentration and whether leak in extranal packing 2, indicate through the colour change state, more directly perceived, striking, simple and convenient.
Experiments prove that in the process of filling carbon dioxide gas into the outer package 2, when the content of the carbon dioxide in the outer package 2 is 0%, the color of the indicator label 3 is blue, after the outer package is filled with the carbon dioxide gas, when the content of the carbon dioxide in the outer package is gradually increased, the color of the indicator label 3 is changed to yellow until becoming yellow, when the outer package 2 is filled with 40-60% of the carbon dioxide gas, the color of the indicator label 3 is yellow, namely, when the outer package 2 is not leaked, the color of the indicator label 3 is yellow; and when extranal packing 2 takes place to leak, the escape takes place for carbon dioxide gas in the extranal packing 2, the concentration reduces, the colour of indicator instruction label 3 is changed into green, dark green by khaki in proper order, the colour of indicator instruction label 3 is green when carbon dioxide gas is 20% in extranal packing 2, the colour of indicator instruction label 3 is dark green when carbon dioxide gas is 0% in extranal packing 2, namely, when the colour of indicator instruction label 3 is green, indicate extranal packing 2 to be in the leakage state, instruct through the colour change state, it is more directly perceived, striking, simple and convenient.
Furthermore, in this embodiment, it is also considered that the ampoule bottle 1 is a polypropylene ampoule bottle, the outer side of the ampoule bottle 1 is provided with scale lines 10, and the label 11 is attached to the outer side of the ampoule bottle 1. The sodium bicarbonate injection is alkaline, if the sodium bicarbonate injection is filled in a glass ampoule, glass desquamation is easily caused, potential risks can be caused by glass packaging and plastic packaging with poor gas barrier effect, and the problems can be solved by a polypropylene ampoule bottle and an outer packaging bag with high barrier property.
Furthermore, it can be considered in this embodiment that the bottle body part 8 and the cap sealing part 6 are connected to form a closed integrated structure through the mouth part 7 of the splash-proof liquid bottle, the middle part of the mouth part 7 of the splash-proof liquid bottle is contracted inwards to form a twist-off groove 71, and the thickness of the twist-off groove 71 is the thinnest. When the handle part 5 is rotated, the twist-off groove 71 of the mouth part 7 of the splash-proof liquid bottle is easier to twist off due to the thinnest thickness, thereby being convenient for the operation of medical personnel, and the twist-off groove 71 is in a retraction design, thereby being more helpful to prevent the sodium bicarbonate injection in the bottle body part 8 from splashing outwards.
Furthermore, it is also contemplated in this embodiment that the indicator tag 3 is freely present in the closed storage cavity 9, and the protective film 4 is a film bag structure wrapped around the outside of the indicator tag 3. Indicator sign 3 independently packs through protection film 4 and places in extranal packing 2, can give normal instruction when the concentration of protective gas changes, or the leakage of extranal packing 2, feeds back to people in time, and protection film 4 can prevent that indicator sign 3 internal water loss, diffusion from causing the indicator to become invalid.
Example 2:
as shown in fig. 3 and 4, the indicator label 3 is disposed on the outer side of the label 11, and the label 11 includes a laminating layer 12, a paper layer, a printed paper layer 13, and an adhesive layer 14, which are sequentially stacked. The paper layer and the printing paper layer 13 are printed with patterns and characters to play a role of identification, the self-adhesive layer 14 is used for providing viscosity to enable the label to be flatly attached to the ampoule bottle, and the laminating layer 12 provides certain toughness and protects the outer surface of the label.
Furthermore, it is also contemplated in this embodiment that the indicator label 3 is welded to the outer surface of the composite film layer 12, and the protective film 4 is formed on the outer side of the indicator label 3, so that the indicator label 3 is hermetically wrapped between the protective film 4 and the composite film layer 12. The welding compounding can be but not limited to the form of hot welding, gluing, electrostatic adsorption and the like, and meanwhile, the indicator label 3 is wrapped between the protective film 4 and the laminating layer 12 in a sealing mode, so that the indicator label 3 is not polluted, the indicator label 3 is compounded on the label 11 in a welding mode, normal indication can be given when the outer package leaks, the loading link of a single indicator is reduced, the production speed is consistent with that of a labeling machine, and the purpose of improving the production efficiency is achieved.
Furthermore, it is also considered in this embodiment that the protective film 4 and the composite film layer 12 are respectively an OPP/CPP composite film. Not only can be used for providing certain toughness and protecting the outer surface of the label 11 so that the label 11 is not easy to damage, but also can prevent the indicator from losing efficacy caused by the loss and the diffusion of water in the indicator label 3.
To sum up, the utility model provides a can give normal instruction when the concentration change of protective gas, or the leakage of extranal packing to can prevent that the area of the interference of vapor, oxygen and carbon dioxide gas in the external world from instructing the sodium bicarbonate injection plastic packaging system of leaking the function.
The above embodiments are described in detail, but the above description is only for the preferred embodiments of the present invention, and should not be construed as limiting the scope of the present invention. All the equivalent changes and improvements made according to the application scope of the present invention should still fall within the patent coverage of the present invention.

Claims (9)

1. The utility model provides a sodium bicarbonate injection plastic packaging system of function is leaked in area instruction, locates the outside extranal packing of ampoule, its characterized in that including ampoule, the sealed cowling that is equipped with sodium bicarbonate injection: be filled with protective gas between ampoule and the extranal packing, still be equipped with the indicator instruction sign that is used for instructing whether the extranal packing leaks between ampoule and the extranal packing, the indicator instruction signs the outside and is equipped with the protection film, the ampoule is including the handle portion, the cap portion, splashproof liquid bottle oral area, the body portion that connect gradually.
2. The sodium bicarbonate injection plastic packaging system with leakage indication function of claim 1, wherein: the extranal packing is the outer packing bag of high resistant barrier property, and the cavity is deposited in its inside closed that supplies the ampoule to deposit that forms, the material structure of extranal packing is composite construction, and its material structure is formed for two kinds at least complex in high resistant barrier polyester film, biaxial stretching nylon film, the curtain coating polypropylene film.
3. The sodium bicarbonate injection plastic packaging system with leakage indication function of claim 1, wherein: the protective gas is carbon dioxide gas, the outer package is filled with 40% -60% of the carbon dioxide gas, and the indicator label displays different colors according to the concentration of the carbon dioxide gas in the outer package and the sealing/leakage state of the outer package.
4. The sodium bicarbonate injection plastic packaging system with leakage indication function of claim 3, wherein: the ampoule is polypropylene ampoule, the ampoule outside is equipped with the scale mark, the ampoule pastes outward and is equipped with the label.
5. The sodium bicarbonate injection plastic packaging system with leakage indication function of claim 4, wherein: the bottle body part and the sealing cap part are connected into a closed integrated structure through the mouth part of the splash-proof liquid bottle, the middle part of the mouth part of the splash-proof liquid bottle is contracted inwards to form a twisting groove, and the thickness of the twisting groove is the thinnest.
6. The sodium bicarbonate injection plastic packaging system with leakage indication function according to any one of claims 1-5, characterized in that: the indicator is characterized in that the indicator is freely arranged in the closed storage cavity, and the protective film is of a film bag structure wrapped on the outer side of the indicator.
7. The sodium bicarbonate injection plastic packaging system with leakage indication function according to any one of claims 1-5, characterized in that: the indicator is characterized in that the indicator label is arranged on the outer side of the label, and the label comprises a composite film layer, a paper layer, a printing paper layer and an adhesive layer which are sequentially overlapped.
8. The sodium bicarbonate injection plastic packaging system with leakage indication function of claim 7, wherein: the indicator label is welded on the outer surface of the laminating layer, and the protective film is formed on the outer side of the indicator label, so that the indicator label is hermetically wrapped between the protective film and the laminating layer.
9. The sodium bicarbonate injection plastic packaging system with leakage indication function of claim 8, wherein: the protective film and the laminating layer are both OPP/CPP composite films.
CN201922400226.1U 2019-12-27 2019-12-27 Sodium bicarbonate injection plastic packaging system with leakage indicating function Active CN211894410U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112952536A (en) * 2021-04-16 2021-06-11 北京镭海激光科技有限公司 Seal off formula carbon dioxide laser pipe with leak gas detection surveys
CN112957254A (en) * 2021-02-04 2021-06-15 南京天华科技开发有限责任公司 Carbon dioxide indicator, applications and methods

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112957254A (en) * 2021-02-04 2021-06-15 南京天华科技开发有限责任公司 Carbon dioxide indicator, applications and methods
CN112952536A (en) * 2021-04-16 2021-06-11 北京镭海激光科技有限公司 Seal off formula carbon dioxide laser pipe with leak gas detection surveys

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